{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:51:05Z","timestamp":1792799465742,"version":"4.5.0"},"reference-count":234,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Methods"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.ymeth.2026.01.006","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T23:34:58Z","timestamp":1768088098000},"page":"107-131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["The clinical potential and limitations of metal-organic frameworks (MOFs) in dentistry"],"prefix":"10.1016","volume":"247","author":[{"given":"Wael Sheet","family":"Hussein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Fawzi","family":"Al-Hussainy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumya V.","family":"Menon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laxmidhar","family":"Maharana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sabarivani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunjan","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aashna","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khabilov","family":"Nigman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayder Naji","family":"Sameer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasim M.","family":"Salih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohaned","family":"Adil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saman","family":"Kalantari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0005","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.ijom.2014.10.023","article-title":"Evaluation of survival and success rates of dental implants reported in longitudinal studies with a follow-up period of at least 10 years: a systematic review","volume":"44","author":"Moraschini","year":"2015","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.ymeth.2026.01.006_b0010","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/jcpe.12957","article-title":"Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Berglundh","year":"2018","journal-title":"J. Clin. Periodontol."},{"issue":"2","key":"10.1016\/j.ymeth.2026.01.006_b0015","first-page":"249","article-title":"Management of edentulous patients","volume":"63","author":"Lee","year":"2019","journal-title":"Dental Clinics"},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0020","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/prd.12323","article-title":"Recent epidemiologic trends in periodontitis in the USA","volume":"82","author":"Eke","year":"2000","journal-title":"Periodontology"},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0025","doi-asserted-by":"crossref","first-page":"932","DOI":"10.3390\/ma8030932","article-title":"A critical review of dental implant materials with an emphasis on titanium versus zirconia","volume":"8","author":"Osman","year":"2015","journal-title":"Materials"},{"key":"10.1016\/j.ymeth.2026.01.006_b0030","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s10856-011-4246-2","article-title":"Surface modification of Ti\u20136Al\u20134V alloy for biomineralization and specific biological response: Part I, inorganic modification","volume":"22","author":"Ferraris","year":"2011","journal-title":"J. Mater. Sci. - Mater. Med."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0035","first-page":"76","article-title":"Nonsurgical treatment of periodontitis, Journal of Evidence Based","volume":"12","author":"Sanz","year":"2012","journal-title":"Dent. Pract."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0040","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12951-023-02284-5","article-title":"Spotlight on therapeutic efficiency of green synthesis metals and their oxide nanoparticles in periodontitis","volume":"22","author":"Kiarashi","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.ymeth.2026.01.006_b0045","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/978-3-030-21583-5_12","article-title":"Recent advances in nanodentistry","author":"Izadi","year":"2020","journal-title":"Applications of Biomedical Engineering in Dentistry"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0050","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.3390\/app12042008","article-title":"Emergence of Nano-dentistry as a reality of contemporary dentistry","volume":"12","author":"Kochan","year":"2022","journal-title":"Appl. Sci."},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e04890","article-title":"Prospects of nanodentistry for the diagnosis and treatment of maxillofacial pathologies and cancers","volume":"6","author":"Adeola","year":"2020","journal-title":"Heliyon"},{"issue":"11","key":"10.1016\/j.ymeth.2026.01.006_b0060","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/j.dental.2020.08.006","article-title":"Nanotechnology in dentistry: Present and future perspectives on dental nanomaterials","volume":"36","author":"Jandt","year":"2020","journal-title":"Dent. Mater."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0065","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1186\/s12951-023-02042-7","article-title":"Recent advances in metal nanoparticles to treat periodontitis","volume":"21","author":"Nasiri","year":"2023","journal-title":"J. Nanobiotechnol."},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0070","doi-asserted-by":"crossref","first-page":"4148","DOI":"10.1172\/JCI120406","article-title":"HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection","volume":"128","author":"Li","year":"2018","journal-title":"J. Clin. Invest."},{"issue":"8","key":"10.1016\/j.ymeth.2026.01.006_b0075","article-title":"Fighting Antibiotic\u2010Resistant Bacteria: Promising Strategies Orchestrated by Molecularly Imprinted Polymers","volume":"61","author":"B. Tse Sum Bui, T. Auroy, K. Haupt","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0080","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3390\/jfb13040215","article-title":"MOFs and MOF-derived materials for antibacterial application","volume":"13","author":"Zhang","year":"2022","journal-title":"Journal of Functional Biomaterials"},{"issue":"13","key":"10.1016\/j.ymeth.2026.01.006_b0085","doi-asserted-by":"crossref","first-page":"4685","DOI":"10.3390\/ma16134685","article-title":"Innovative metal-organic frameworks for targeted oral cancer therapy: A review","volume":"16","author":"Mousavi","year":"2023","journal-title":"Materials"},{"key":"10.1016\/j.ymeth.2026.01.006_b0090","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.colcom.2017.11.004","article-title":"Maintaining stable Zeolitic Imidazolate Framework (ZIF) templates during polyelectrolyte multilayer coating","volume":"22","author":"Beyer","year":"2018","journal-title":"Colloid Interface Sci. Commun."},{"issue":"6","key":"10.1016\/j.ymeth.2026.01.006_b0095","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1002\/jbm.b.32707","article-title":"Surface modification of magnesium alloys developed for bioabsorbable orthopedic implants: a general review","volume":"100","author":"Wang","year":"2012","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"37","key":"10.1016\/j.ymeth.2026.01.006_b0100","first-page":"31411","volume":"9","author":"Bhanja","year":"2017","journal-title":"Covalent organic framework material bearing phloroglucinol building units as a potent anticancer agent, ACS applied materials & interfaces"},{"issue":"20","key":"10.1016\/j.ymeth.2026.01.006_b0105","doi-asserted-by":"crossref","first-page":"12278","DOI":"10.1021\/acs.chemrev.1c00243","article-title":"Metal\u2013organic framework-based hierarchically porous materials: synthesis and applications","volume":"121","author":"Cai","year":"2021","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ymeth.2026.01.006_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.132867","article-title":"Delivery of therapeutic miRNAs using nanoscale zeolitic imidazolate framework for accelerating vascularized bone regeneration","volume":"430","author":"Feng","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0115","article-title":"Senescence-associated \u03b2-galactosidase detection in human oral cancer samples using bimetallic (Fe, Cu)-MOF-919 impedimetric immunosensor","volume":"9","author":"Vijayaraghavan","year":"2025","journal-title":"Sens. Actuators Rep."},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2022.05.041","article-title":"Applications of metal nanoparticles\/metal-organic frameworks composites in sensing field","volume":"34","author":"Xu","year":"2023","journal-title":"Chin. Chem. Lett."},{"key":"10.1016\/j.ymeth.2026.01.006_b0125","first-page":"1034","article-title":"New Materials in Oral Surgery","author":"Grassia","year":"2020","journal-title":"MDPI"},{"issue":"1\u20132","key":"10.1016\/j.ymeth.2026.01.006_b0130","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.ijpharm.2016.06.011","article-title":"Targeted chitosan-based bionanocomposites for controlled oral mucosal delivery of chlorhexidine","volume":"509","author":"Onnainty","year":"2016","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ymeth.2026.01.006_b0135","article-title":"MOF-based platforms on diabetic disease: Advanced and prospect of effective diagnosing and therapy","volume":"106520","author":"Ma","year":"2025","journal-title":"React. Funct. Polym."},{"issue":"43","key":"10.1016\/j.ymeth.2026.01.006_b0140","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202308589","article-title":"Biomedical metal\u2013organic framework materials: perspectives and challenges","volume":"34","author":"Wang","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"16","key":"10.1016\/j.ymeth.2026.01.006_b0145","doi-asserted-by":"crossref","first-page":"5415","DOI":"10.1039\/C4CS90059F","article-title":"Metal\u2013organic frameworks (MOFs)","volume":"43","author":"Kitagawa","year":"2014","journal-title":"Chem. Soc. Rev."},{"issue":"37","key":"10.1016\/j.ymeth.2026.01.006_b0150","article-title":"Stable metal\u2013organic frameworks: design, synthesis, and applications","volume":"30","author":"Yuan","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.ymeth.2026.01.006_b0155","first-page":"673","article-title":"Introduction to metal\u2013organic frameworks","author":"Zhou","year":"2012","journal-title":"ACS Publications"},{"key":"10.1016\/j.ymeth.2026.01.006_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2021.213804","article-title":"Unconventional inorganic precursors determine the growth of metal-organic frameworks","volume":"434","author":"Zhong","year":"2021","journal-title":"Coord. Chem. Rev."},{"issue":"49","key":"10.1016\/j.ymeth.2026.01.006_b0165","doi-asserted-by":"crossref","first-page":"44507","DOI":"10.1021\/acsomega.2c05310","article-title":"Review on metal\u2013organic framework classification, synthetic approaches, and influencing factors: applications in energy, drug delivery, and wastewater treatment","volume":"7","author":"Yusuf","year":"2022","journal-title":"ACS Omega"},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0170","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1039\/C1CS15055C","article-title":"Ligand design for functional metal\u2013organic frameworks","volume":"41","author":"Paz","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.ymeth.2026.01.006_b0175","series-title":"Nanomaterials derived from metal-organic frameworks for energy storage supercapacitor application","first-page":"441","author":"Gurusamy","year":"2021"},{"issue":"13\u201314","key":"10.1016\/j.ymeth.2026.01.006_b0180","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1016\/j.addr.2013.07.011","article-title":"Nanotechnology as a therapeutic tool to combat microbial resistance","volume":"65","author":"Pelgrift","year":"2013","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0185","doi-asserted-by":"crossref","first-page":"3808","DOI":"10.1021\/acsnano.0c09617","article-title":"Metal\u2013organic-framework-based materials for antimicrobial applications","volume":"15","author":"Li","year":"2021","journal-title":"ACS Nano"},{"issue":"16","key":"10.1016\/j.ymeth.2026.01.006_b0190","doi-asserted-by":"crossref","first-page":"7138","DOI":"10.1039\/D2CS00460G","article-title":"Metal organic framework-based antibacterial agents and their underlying mechanisms","volume":"51","author":"Han","year":"2022","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.ymeth.2026.01.006_b0195","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.2147\/IDR.S177247","article-title":"Health care-associated infections\u2013an overview","author":"Haque","year":"2018","journal-title":"Infect. Drug Resist."},{"issue":"2","key":"10.1016\/j.ymeth.2026.01.006_b0200","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/NAN.0000000000000313","article-title":"Understanding the economic impact of health care-associated infections: a cost perspective analysis","volume":"42","author":"Douglas Scott","year":"2019","journal-title":"J. Infus. Nurs."},{"key":"10.1016\/j.ymeth.2026.01.006_b0205","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jinorgbio.2014.05.005","article-title":"Silver carboxylate metal\u2013organic frameworks with highly antibacterial activity and biocompatibility","volume":"138","author":"Lu","year":"2014","journal-title":"J. Inorg. Biochem."},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0210","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1021\/acs.iecr.9b05659","article-title":"Killing oral bacteria using metal\u2013organic frameworks","volume":"59","author":"Cao","year":"2020","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.ymeth.2026.01.006_b0215","first-page":"1","article-title":"Cross mechanism-of-action classification of antibiotics by global","volume":"64","author":"Rourke","year":"2020","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ymeth.2026.01.006_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.134975","article-title":"Metal organic frameworks for antibacterial applications","volume":"435","author":"Yan","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2019.109862","article-title":"Antibacterial properties of nanoporous graphene oxide\/cobalt metal organic framework","volume":"104","author":"Hatamie","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0230","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1111\/1541-4337.12515","article-title":"Antibacterial applications of metal\u2013organic frameworks and their composites","volume":"19","author":"Shen","year":"2020","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.ymeth.2026.01.006_b0235","article-title":"Regulating electron transfer between valence-variable Fe and Cu sites in bimetallic MOFs to enhance ROS generation for day-night antibacterial efficacy","volume":"111553","author":"Cheng","year":"2025","journal-title":"Chin. Chem. Lett."},{"issue":"11","key":"10.1016\/j.ymeth.2026.01.006_b0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e31788","article-title":"Gallium-based metal\u2013organic frameworks with antibacterial and anti-inflammatory properties for oral health protection","volume":"10","author":"Song","year":"2024","journal-title":"Heliyon"},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0245","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202409087","article-title":"Nanotherapies based on ROS regulation in oral diseases","volume":"12","author":"Luo","year":"2025","journal-title":"Adv. Sci."},{"issue":"27","key":"10.1016\/j.ymeth.2026.01.006_b0250","doi-asserted-by":"crossref","first-page":"10186","DOI":"10.1073\/pnas.0602439103","article-title":"Exceptional chemical and thermal stability of zeolitic imidazolate frameworks","volume":"103","author":"Park","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"37","key":"10.1016\/j.ymeth.2026.01.006_b0255","doi-asserted-by":"crossref","first-page":"12429","DOI":"10.1039\/D1SC02017J","article-title":"Multiple-mRNA-controlled and heat-driven drug release from gold nanocages in targeted chemo-photothermal therapy for tumors","volume":"12","author":"Zhang","year":"2021","journal-title":"Chem. Sci."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0260","article-title":"Porous metal-organic frameworks for gas storage and separation: Status and challenges","volume":"1","author":"Li","year":"2019","journal-title":"EnergyChem"},{"key":"10.1016\/j.ymeth.2026.01.006_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.129577","article-title":"A metal-organic-framework incorporated vascular graft for sustained nitric oxide generation and long-term vascular patency","volume":"421","author":"Zhang","year":"2021","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2021.109646","article-title":"Metal-organic frameworks-derived bimetallic nanozyme platform enhances cytotoxic effect of photodynamic therapy in hypoxic cancer cells","volume":"204","author":"Han","year":"2021","journal-title":"Mater. Des."},{"key":"10.1016\/j.ymeth.2026.01.006_b0275","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.biomaterials.2017.01.017","article-title":"A simple and powerful co-delivery system based on pH-responsive metal-organic frameworks for enhanced cancer immunotherapy","volume":"122","author":"Duan","year":"2017","journal-title":"Biomaterials"},{"issue":"33","key":"10.1016\/j.ymeth.2026.01.006_b0280","doi-asserted-by":"crossref","first-page":"11725","DOI":"10.1039\/D3DT01301D","article-title":"Metal\u2013organic framework based drug delivery systems as smart carriers for release of poorly soluble drugs hydrochlorothiazide and dapsone","volume":"52","author":"Yadav","year":"2023","journal-title":"Dalton Trans."},{"issue":"18","key":"10.1016\/j.ymeth.2026.01.006_b0285","first-page":"2487","volume":"21","author":"Karami","year":"2021","journal-title":"Recent advances in metal-organic frameworks as anticancer drug delivery systems: A review, Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents)"},{"issue":"15","key":"10.1016\/j.ymeth.2026.01.006_b0290","doi-asserted-by":"crossref","first-page":"5573","DOI":"10.1039\/D1QM00784J","article-title":"Metal\u2013organic frameworks towards bio-medical applications","volume":"5","author":"Ma","year":"2021","journal-title":"Mater. Chem. Front."},{"key":"10.1016\/j.ymeth.2026.01.006_b0295","article-title":"Covalent organic frameworks (COFs) and metal-organic frameworks (MOFs) as electrochemical sensors for the efficient detection of pharmaceutical residues","volume":"107928","author":"Mohan","year":"2023","journal-title":"Environ. Int."},{"issue":"8","key":"10.1016\/j.ymeth.2026.01.006_b0300","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1021\/acsbiomaterials.0c00564","article-title":"MOF-based erodible system for on-demand release of bioactive flavonoid at the polymer\u2013tissue interface","volume":"6","author":"Bim-J\u00fanior","year":"2020","journal-title":"ACS Biomater Sci. Eng."},{"issue":"10","key":"10.1016\/j.ymeth.2026.01.006_b0305","doi-asserted-by":"crossref","first-page":"3726","DOI":"10.1039\/D3BM00191A","article-title":"Transformation of the shape and shrinking the size of acid-resistant metal\u2013organic frameworks (MOFs) for use as the vehicle of oral proteins","volume":"11","author":"Yang","year":"2023","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.ymeth.2026.01.006_b0310","doi-asserted-by":"crossref","unstructured":"J. Qin, K. Jiang, Z. Yuan, L. Zhang, B. Chen, A Multifunctional MOF Heterojunction for Combating Antibiotic Resistance and Promoting Regenerative Immunity, ACS nano (2025).","DOI":"10.1021\/acsnano.5c12462"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0315","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1021\/acsbiomaterials.5c00084","article-title":"Bacteria-Responsive Drug Delivery System Utilizing Carboxymethyl Cellulose-Functionalized Metal\u2013Organic Framework for Enhanced Antibacterial Efficacy","volume":"11","author":"Yuan","year":"2025","journal-title":"ACS Biomater Sci. Eng."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0320","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3390\/md14010002","article-title":"In vitro and in vivo anticancer activity of pardaxin against proliferation and growth of oral squamous cell carcinoma","volume":"14","author":"Han","year":"2015","journal-title":"Mar. Drugs"},{"issue":"7","key":"10.1016\/j.ymeth.2026.01.006_b0325","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1021\/jacsau.2c00376","article-title":"Metal\u2013organic frameworks and covalent organic frameworks: Emerging advances and applications","volume":"2","author":"Jones","year":"2022","journal-title":"JACS Au"},{"key":"10.1016\/j.ymeth.2026.01.006_b0330","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.trac.2019.06.007","article-title":"A review on metal-organic frameworks: Synthesis and applications","volume":"118","author":"Safaei","year":"2019","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.ymeth.2026.01.006_b0335","article-title":"Targeted delivery of Fenton reaction packages and drugs for cancer theranostics","volume":"26","author":"Fu","year":"2022","journal-title":"Appl. Mater. Today"},{"issue":"23","key":"10.1016\/j.ymeth.2026.01.006_b0340","doi-asserted-by":"crossref","first-page":"7277","DOI":"10.3390\/ma14237277","article-title":"Metal\u2013organic frameworks (MOFs) for cancer therapy","volume":"14","author":"Saeb","year":"2021","journal-title":"Materials"},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0345","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1021\/acs.accounts.0c00313","article-title":"Nanoscale metal\u2013organic frameworks for cancer immunotherapy","volume":"53","author":"Ni","year":"2020","journal-title":"Acc. Chem. Res."},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.arabjc.2024.105935","article-title":"pH-responsive berberine release from metal-organic framework based nanocarriers by regulating oxidative stress for targeted therapy of oral squamous cell carcinoma","volume":"17","author":"Li","year":"2024","journal-title":"Arab. J. Chem."},{"key":"10.1016\/j.ymeth.2026.01.006_b0355","doi-asserted-by":"crossref","DOI":"10.1021\/acsbiomaterials.5c01469","article-title":"Research Progress on MOF-Based Biomimetic Nanoplatforms for Tumor Theranostics","author":"Shao","year":"2025","journal-title":"ACS Biomater Sci. Eng."},{"key":"10.1016\/j.ymeth.2026.01.006_b0360","doi-asserted-by":"crossref","DOI":"10.1002\/bmm2.70029","article-title":"Multifunctional H2S\u2010activated metal\u2010organic framework systems for targeted colorectal cancer imaging and synergistic copper\u2010induced tumor regression","author":"Zheng","year":"2025","journal-title":"BMEMat"},{"issue":"37","key":"10.1016\/j.ymeth.2026.01.006_b0365","doi-asserted-by":"crossref","first-page":"33496","DOI":"10.1021\/acsnano.5c10754","article-title":"Nanobiocatalyst-Driven Spatiotemporal Hydrogen Delivery Induces Dormancy Potentiated Catalytic Tumor Therapy","volume":"19","author":"Cao","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.ymeth.2026.01.006_b0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2024.138461","article-title":"Construction of an anticancer system based on medi-MOF-1 and Mn ions for theranostic application","volume":"1312","author":"Hu","year":"2024","journal-title":"J. Mol. Struct."},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0375","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3390\/inorganics12090231","article-title":"Fructose-Based Metal\u2013Organic Framework as a Means to Synthesize Sr-Loaded Chitosan Nanospheres with NLO Properties for Theranostic Applications in Radiotherapy","volume":"12","author":"Cioci","year":"2024","journal-title":"Inorganics"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0380","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/apm.12688","article-title":"Dental biofilm infections\u2013an update","volume":"125","author":"Larsen","year":"2017","journal-title":"APMIS"},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0385","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/s12951-024-02472-x","article-title":"The potential use of nanozymes as an antibacterial agents in oral infection, periodontitis, and peri-implantitis","volume":"22","author":"Hosseini Hooshiar","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0390","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1039\/D1TB02174E","article-title":"A periodontal tissue regeneration strategy via biphasic release of zeolitic imidazolate framework-8 and FK506 using a uniaxial electrospun Janus nanofiber","volume":"10","author":"Sun","year":"2022","journal-title":"J. Mater. Chem. B"},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0395","doi-asserted-by":"crossref","first-page":"471","DOI":"10.4103\/jisp.jisp_555_22","article-title":"Evaluation of bioactivity and biodegradability of a biomimetic soft tissue scaffold for clinical use: An in vitro study","volume":"27","author":"Houshmand","year":"2023","journal-title":"Journal of Indian Society of Periodontology"},{"key":"10.1016\/j.ymeth.2026.01.006_b0400","doi-asserted-by":"crossref","DOI":"10.1016\/j.jddst.2022.104123","article-title":"ATP-responsive zeolitic imidazolate framework-90 for superoxide dismutase delivery to reduce reactive oxygen species in MG-63 cells","volume":"80","author":"Wang","year":"2023","journal-title":"J. Drug Delivery Sci. Technol."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0405","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S1473-3099(18)30605-4","article-title":"Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis","volume":"19","author":"Cassini","year":"2019","journal-title":"Lancet Infect. Dis."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0410","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.matlet.2008.09.010","article-title":"Ultrasonic synthesis of the microporous metal\u2013organic framework Cu3 (BTC) 2 at ambient temperature and pressure: An efficient and environmentally friendly method","volume":"63","author":"Li","year":"2009","journal-title":"Mater. Lett."},{"issue":"13","key":"10.1016\/j.ymeth.2026.01.006_b0415","doi-asserted-by":"crossref","first-page":"7360","DOI":"10.1039\/D0RA00108B","article-title":"An NIF-doped ZIF-8 hybrid membrane for continuous antimicrobial treatment","volume":"10","author":"Luo","year":"2020","journal-title":"RSC Adv."},{"issue":"7","key":"10.1016\/j.ymeth.2026.01.006_b0420","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1021\/ja512311a","article-title":"Introduction of functionality, selection of topology, and enhancement of gas adsorption in multivariate metal\u2013organic framework-177","volume":"137","author":"Zhang","year":"2015","journal-title":"J. Am. Chem. Soc."},{"issue":"12","key":"10.1016\/j.ymeth.2026.01.006_b0425","doi-asserted-by":"crossref","first-page":"4513","DOI":"10.1021\/jacs.7b00925","article-title":"Targeted drug delivery in covalent organic nanosheets (CONs) via sequential postsynthetic modification","volume":"139","author":"Mitra","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.ymeth.2026.01.006_b0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2024.114238","article-title":"Nanoscale fluconazole-constructed metal-organic frameworks with smart drug release for eradication of Candida biofilms in vulvovaginitis infection","volume":"245","author":"Wang","year":"2025","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"32","key":"10.1016\/j.ymeth.2026.01.006_b0435","doi-asserted-by":"crossref","first-page":"45413","DOI":"10.1021\/acsami.5c06407","article-title":"ZIF-8-Based Composites for Enhanced Biofilm Penetration and Synergistic Antibacterial Therapy against Periodontal Pathogens","volume":"17","author":"Weng","year":"2025","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.ymeth.2026.01.006_b0440","doi-asserted-by":"crossref","DOI":"10.1016\/j.identj.2025.104543","article-title":"MOF Nanosystem Activated By Caries Microenvironment For Caries Repair","volume":"75","author":"Cao","year":"2025","journal-title":"Int. Dent. J."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0445","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1038\/s41598-025-85123-x","article-title":"Preparation of Ag-Metal organic frameworks-loaded Sodium Alginate Hydrogel for the treatment of periodontitis","volume":"15","author":"Wang","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ymeth.2026.01.006_b0450","article-title":"Antibacterial Silver Modified Gallium Metal-Organic Frameworks for Odontogenic Infections","volume":"rs. 3","author":"Gomes","year":"2025","journal-title":"Research Square"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0455","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s11095-019-2589-4","article-title":"Metal organic framework (MOF) particles as potential bacteria-mimicking delivery systems for infectious diseases: characterization and cellular internalization in alveolar macrophages","volume":"36","author":"Guo","year":"2019","journal-title":"Pharm. Res."},{"key":"10.1016\/j.ymeth.2026.01.006_b0460","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2021.118187","article-title":"Controlled release of iodine from cross-linked cyclodextrin metal-organic frameworks for prolonged periodontal pocket therapy","volume":"267","author":"Lu","year":"2021","journal-title":"Carbohydr. Polym."},{"issue":"33","key":"10.1016\/j.ymeth.2026.01.006_b0465","doi-asserted-by":"crossref","first-page":"26647","DOI":"10.1039\/D5RA01665G","article-title":"Zirconium-based MOFs as pH-responsive drug delivery systems: encapsulation and release profiles of ciprofloxacin","volume":"15","author":"Ishfaq","year":"2025","journal-title":"RSC Adv."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0470","doi-asserted-by":"crossref","DOI":"10.1080\/10717544.2025.2522109","article-title":"Advances in pH-responsive drug delivery systems for periodontitis treatment","volume":"32","author":"Sha","year":"2025","journal-title":"Drug Deliv."},{"key":"10.1016\/j.ymeth.2026.01.006_b0475","article-title":"Metal\u2013organic frameworks (MOFs) in drug Delivery: Emerging trends, functional enhancements, and biocompatibility challenges","volume":"107284","author":"Filiz","year":"2025","journal-title":"J. Drug Delivery Sci. Technol."},{"issue":"10","key":"10.1016\/j.ymeth.2026.01.006_b0480","doi-asserted-by":"crossref","first-page":"813","DOI":"10.3390\/gels11100813","article-title":"Preparation and Characterization of an Acid-Responsive ZIF-8 Hydrogel Dressing with Sustained-Release Function for Targeted Therapy of Periodontitis","volume":"11","author":"Chen","year":"2025","journal-title":"Gels"},{"issue":"44","key":"10.1016\/j.ymeth.2026.01.006_b0485","doi-asserted-by":"crossref","first-page":"6955","DOI":"10.1039\/C9TB01743G","article-title":"Novel nanoparticles of cerium-doped zeolitic imidazolate frameworks with dual benefits of antibacterial and anti-inflammatory functions against periodontitis","volume":"7","author":"Li","year":"2019","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.ymeth.2026.01.006_b0490","article-title":"Adhesive two-dimensional bimetallic organic framework nanozymes for regulating inflammation and eradicating bacteria in periodontal disease","volume":"164263","author":"Fan","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0495","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.133279","article-title":"Theory-screened MOF-based single-atom catalysts for facile and effective therapy of biofilm-induced periodontitis","volume":"431","author":"Yu","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0500","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2024.102280","article-title":"A nano-oxygen generator for enhanced light-controlled elimination of anaerobic bacteria in periodontal infections","volume":"56","author":"Dong","year":"2024","journal-title":"Nano Today"},{"key":"10.1016\/j.ymeth.2026.01.006_b0505","doi-asserted-by":"crossref","unstructured":"Q. Luo, Y. Yang, C. Ho, Z. Li, W. Chiu, A. Li, Y. Dai, W. Li, X. Zhang, MOF-Integrated Responsive Injectable Self-healing Hydrogel System for Bone Regeneration in Periodontitis, (2024).","DOI":"10.21203\/rs.3.rs-3852307\/v1"},{"key":"10.1016\/j.ymeth.2026.01.006_b0510","article-title":"Zinc\u2010Cobalt Bimetallic Organic Frameworks with Antioxidative and Osteogenic Activities for Periodontitis Treatment","volume":"2412065","author":"Tang","year":"2025","journal-title":"Small"},{"key":"10.1016\/j.ymeth.2026.01.006_b0515","article-title":"Dexamethasone-loaded zeolitic imidazolate frameworks nanocomposite hydrogel with antibacterial and anti-inflammatory effects for periodontitis treatment","volume":"16","author":"Li","year":"2022","journal-title":"Mater. Today Bio"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0520","first-page":"379","article-title":"Application of sulfylated calcium alginate composite hydrogel loaded with zinc-based zeolite imidazole for the treatment of periodontitis","volume":"31","author":"Ming","year":"2022","journal-title":"Shanghai Journal of Stomatology"},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0525","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1186\/s12951-023-02244-z","article-title":"Reprogramming mitochondrial metabolism of macrophages by miRNA-released microporous coatings to prevent peri-implantitis","volume":"21","author":"Zhang","year":"2023","journal-title":"J. Nanobiotechnol."},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0530","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1007\/s10895-020-02575-2","article-title":"A fluorescent zn (II)-Coordination polymer: selective detection of Nitrofurantoin and Prevention of Peri-implantitis after Ultrafine-Grained Titanium Implant by reducing Inflammatory cytokines Release","volume":"30","author":"Liu","year":"2020","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.ymeth.2026.01.006_b0535","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2025.123327","article-title":"Nano Sim@ ZIF8@ PDA modified injectable temperature sensitive nanocomposite hydrogel for photothermal\/drug therapy for peri-implantitis","volume":"354","author":"Liu","year":"2025","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ymeth.2026.01.006_b0540","article-title":"Debridement of contaminated implants using air-polishing coupled with pH-responsive maximin H5-embedded metal-organic frameworks","volume":"11","author":"Zhu","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.ymeth.2026.01.006_b0545","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2022.100917","article-title":"Enzymatic bionanocatalysts for combating peri-implant biofilm infections by specific heat-amplified chemodynamic therapy and innate immunomodulation","volume":"67","author":"Su","year":"2023","journal-title":"Drug Resist. Updat."},{"issue":"14","key":"10.1016\/j.ymeth.2026.01.006_b0550","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abn1701","article-title":"Bioresponsive nano-antibacterials for H2S-sensitized hyperthermia and immunomodulation against refractory implant\u2013related infections","volume":"8","author":"Su","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.ymeth.2026.01.006_b0555","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2022.112840","article-title":"MOF-derived CuO@ ZnO modified titanium implant for synergistic antibacterial ability, osteogenesis and angiogenesis","volume":"219","author":"Si","year":"2022","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.ymeth.2026.01.006_b0560","doi-asserted-by":"crossref","first-page":"0188","DOI":"10.34133\/bmr.0188","article-title":"A pH-Responsive Polyetheretherketone Implant Modified with a Core\u2013Shell Metal\u2013Organic Framework to Promote Antibacterial and Osseointegration Abilities","volume":"29","author":"Ma","year":"2025","journal-title":"Biomaterials Research"},{"key":"10.1016\/j.ymeth.2026.01.006_b0565","first-page":"72","article-title":"Multifunctional magnesium organic framework-based photothermal and pH dual-responsive mouthguard for caries prevention and tooth self-healing promotion","volume":"29","author":"Li","year":"2023","journal-title":"Bioact. Mater."},{"issue":"44","key":"10.1016\/j.ymeth.2026.01.006_b0570","doi-asserted-by":"crossref","first-page":"16189","DOI":"10.1039\/D3DT02816J","article-title":"Oxygen-carrying acid-responsive Cu\/ZIF-8 for photodynamic antibacterial therapy against cariogenic Streptococcus mutans infection","volume":"52","author":"Wang","year":"2023","journal-title":"Dalton Trans."},{"issue":"12","key":"10.1016\/j.ymeth.2026.01.006_b0575","doi-asserted-by":"crossref","DOI":"10.1002\/aoc.70453","article-title":"Bioactive and Antibacterial Fluoride Nanoformulation of Zn\u2010MOFs Loaded With AgNPs: A Potential Substitute for SDF in Caries Management","volume":"39","author":"Sharifinejad","year":"2025","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.ymeth.2026.01.006_b0580","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.pdpdt.2018.08.004","article-title":"Antimicrobial photodynamic therapy assessment of three indocyanine green-loaded metal-organic frameworks against Enterococcus faecalis","volume":"23","author":"Golmohamadpour","year":"2018","journal-title":"Photodiagn. Photodyn. Ther."},{"key":"10.1016\/j.ymeth.2026.01.006_b0585","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2023.104413","article-title":"The pH-responsive zeolitic imidazolate framework nanoparticle as a promising immune-enhancing adjuvant for anti-caries vaccine","volume":"130","author":"Yu","year":"2023","journal-title":"J. Dent."},{"key":"10.1016\/j.ymeth.2026.01.006_b0590","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202527093","article-title":"A MOF\u2010based Core\u2013Shell System Enables Controlled Release and Ordered Assembly of Nano\u2010Hydroxyapatite for Enamel Remineralization","author":"Liang","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"2","key":"10.1016\/j.ymeth.2026.01.006_b0595","first-page":"592","volume":"90","author":"\u00c7\u0131nar","year":"2009","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0600","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/2231-0762.175418","article-title":"Enhancing the antibacterial activity of the gold standard intracanal medicament with incorporation of silver zeolite: An: in vitro: study","volume":"6","author":"Ghatole","year":"2016","journal-title":"Journal of International Society of Preventive and Community Dentistry"},{"key":"10.1016\/j.ymeth.2026.01.006_b0605","article-title":"Ultrasound-assisted synthesis of bismuth-metal organic frameworks for suppressing Porphyromonas gingivalis, 2021 IADR\/AADR\/CADR General Session & Exhibition","author":"Huang","year":"2021","journal-title":"Virtual Conference, International Association for Dental Research. The Journal's web site is \u2026"},{"key":"10.1016\/j.ymeth.2026.01.006_b0610","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.chemosphere.2014.05.029","article-title":"Antimicrobial activity of cobalt imidazolate metal\u2013organic frameworks","volume":"113","author":"Aguado","year":"2014","journal-title":"Chemosphere"},{"issue":"10","key":"10.1016\/j.ymeth.2026.01.006_b0615","doi-asserted-by":"crossref","first-page":"5731","DOI":"10.1021\/nn101390x","article-title":"Toxicity of graphene and graphene oxide nanowalls against bacteria","volume":"4","author":"Akhavan","year":"2010","journal-title":"ACS Nano"},{"issue":"25","key":"10.1016\/j.ymeth.2026.01.006_b0620","doi-asserted-by":"crossref","first-page":"12490","DOI":"10.1021\/jp0623387","article-title":"Incorporation of Co (II) in dealuminated BEA zeolite at lattice tetrahedral sites evidenced by XRD, FTIR, diffuse reflectance UV\u2212 Vis","volume":"110","author":"Dzwigaj","year":"2006","journal-title":"EPR, and TPR, The Journal of Physical Chemistry B"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0625","doi-asserted-by":"crossref","DOI":"10.1063\/5.0206476","article-title":"Application of metal\u2013organic frameworks in stomatology","volume":"14","author":"Zheng","year":"2024","journal-title":"AIP Adv."},{"key":"10.1016\/j.ymeth.2026.01.006_b0630","doi-asserted-by":"crossref","unstructured":"M. Esposito, M.G. Grusovin, H.V. Worthington, Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications, Cochrane Database of Systematic Reviews (7) (2013).","DOI":"10.1002\/14651858.CD003878.pub5"},{"key":"10.1016\/j.ymeth.2026.01.006_b0635","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.jconrel.2019.06.038","article-title":"Local drug delivery systems in the management of periodontitis: A scientific review","volume":"307","author":"Rajeshwari","year":"2019","journal-title":"J. Control. Release"},{"key":"10.1016\/j.ymeth.2026.01.006_b0640","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.2147\/IJN.S231679","article-title":"Green synthesis of zeolite\/Fe2O3 nanocomposites: toxicity & cell proliferation assays and application as a smart iron nanofertilizer","author":"Jahangirian","year":"2020","journal-title":"Int. J. Nanomed."},{"issue":"2","key":"10.1016\/j.ymeth.2026.01.006_b0645","doi-asserted-by":"crossref","DOI":"10.32394\/rpzh.2021.0161","article-title":"In vitro evaluation of antimicrobial efficacy of silver zeolite against common oral pathogens","volume":"72","author":"Panda","year":"2021","journal-title":"Roczniki Pa\u0144stwowego Zak\u0142adu Higieny"},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0650","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3892\/ol.2020.12137","article-title":"Water\u2011soluble propolis and bee pollen of Trigona spp. from South Sulawesi Indonesia induce apoptosis in the human breast cancer MCF\u20117 cell line","volume":"20","author":"Amalia","year":"2020","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.ymeth.2026.01.006_b0655","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.113662","article-title":"Chemical composition, cytotoxicity, and antibacterial activity of propolis from Africanized honeybees and three different Meliponini species","volume":"269","author":"Surek","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"41","key":"10.1016\/j.ymeth.2026.01.006_b0660","doi-asserted-by":"crossref","first-page":"8535","DOI":"10.1039\/D2TB01311H","article-title":"Surface modification of the Ti surface with nanoscale bio-MOF-1 for improving biocompatibility and osteointegration in vitro and in vivo","volume":"10","author":"Wu","year":"2022","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.ymeth.2026.01.006_b0665","article-title":"Optimized fabrication of L-Asp-Cu (II) Bio-MOF for enhanced vascularized bone regeneration","volume":"505","author":"Zhang","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0670","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.jcis.2023.02.149","article-title":"An efficient metal\u2013organic framework-based drug delivery platform for synergistic antibacterial activity and osteogenesis","volume":"640","author":"Si","year":"2023","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.ymeth.2026.01.006_b0675","article-title":"The effect of microgroove pattern modification combined with MOF coating on titanium alloy for the soft tissue integration of percutaneous implants","volume":"149278","author":"Xue","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"14","key":"10.1016\/j.ymeth.2026.01.006_b0680","doi-asserted-by":"crossref","first-page":"17543","DOI":"10.1021\/acsami.2c23107","article-title":"Drug-delivery nanoplatform with synergistic regulation of angiogenesis\u2013osteogenesis coupling for promoting vascularized bone regeneration","volume":"15","author":"Li","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0685","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202202317","article-title":"One\u2010pot facile encapsulation of dimethyloxallyl Glycine by nanoscale zeolitic imidazolate frameworks\u20108 for enhancing vascularized bone regeneration","volume":"12","author":"Zhang","year":"2023","journal-title":"Adv. Healthc. Mater."},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0690","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.3390\/ma14051193","article-title":"Antibacterial activity of propolis-embedded zeolite nanocomposites for implant application","volume":"14","author":"Son","year":"2021","journal-title":"Materials"},{"key":"10.1016\/j.ymeth.2026.01.006_b0695","article-title":"Positive regulation of osteogenesis on titanium surface by modification of nanosized Ca2+-exchanged EMT zeolites","volume":"33","author":"Chi","year":"2022","journal-title":"Mater. Today Commun."},{"key":"10.1016\/j.ymeth.2026.01.006_b0700","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.124446","article-title":"A multifunctional MOF-based nanohybrid as injectable implant platform for drug synergistic oral cancer therapy","volume":"390","author":"Tan","year":"2020","journal-title":"Chem. Eng. J."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0705","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2174\/1570163812666150602144310","article-title":"Targeted cancer therapy: the next generation of cancer treatment","volume":"12","author":"Baudino","year":"2015","journal-title":"Curr. Drug Discov. Technol."},{"key":"10.1016\/j.ymeth.2026.01.006_b0710","article-title":"Theranostic doxorubicin encapsulated FeAu alloy@ metal-organic framework nanostructures enable magnetic hyperthermia and medical imaging in oral carcinoma, Nanomedicine: Nanotechnology","volume":"48","author":"Dhawan","year":"2023","journal-title":"Biology and Medicine"},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0715","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.3390\/ph15091137","article-title":"Antiproliferative and apoptotic effects of graphene oxide@ AlFu MOF based saponin natural product on OSCC line","volume":"15","author":"Mousavi","year":"2022","journal-title":"Pharmaceuticals"},{"issue":"6","key":"10.1016\/j.ymeth.2026.01.006_b0720","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1039\/D3SD00214D","article-title":"Advancing healthcare applications: wearable sensors utilizing metal\u2013organic frameworks","volume":"2","author":"Rebecca","year":"2023","journal-title":"Sensors & Diagnostics"},{"key":"10.1016\/j.ymeth.2026.01.006_b0725","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.copbio.2013.11.005","article-title":"Pathogen-like particles: biomimetic vaccine carriers engineered at the nanoscale","volume":"28","author":"Rosenthal","year":"2014","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.ymeth.2026.01.006_b0730","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2019.110111","article-title":"Synthesis of chitosan coated metal organic frameworks (MOFs) for increasing vancomycin bactericidal potentials against resistant S. aureus strain","volume":"105","author":"Ghaffar","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0735","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1021\/acs.accounts.1c00707","article-title":"Reticular chemistry for highly porous metal\u2013organic frameworks: The chemistry and applications","volume":"55","author":"Chen","year":"2022","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.ymeth.2026.01.006_b0740","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2023.215160","article-title":"Metal\u2013organic framework detectives meet infectious pathogens: A powerful tool against pandemics","volume":"488","author":"Huang","year":"2023","journal-title":"Coord. Chem. Rev."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0745","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s13036-024-00423-6","article-title":"Recent advances in nanomaterial-based biosensor for periodontitis detection","volume":"18","author":"Hooshiar","year":"2024","journal-title":"J. Biol. Eng."},{"issue":"39","key":"10.1016\/j.ymeth.2026.01.006_b0750","doi-asserted-by":"crossref","first-page":"33589","DOI":"10.1021\/acsami.7b07818","article-title":"MOF\u2013bacteriophage biosensor for highly sensitive and specific detection of Staphylococcus aureus","volume":"9","author":"Bhardwaj","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"24","key":"10.1016\/j.ymeth.2026.01.006_b0755","doi-asserted-by":"crossref","first-page":"8544","DOI":"10.1021\/acs.analchem.1c01261","article-title":"Ultrasensitive detection of bacteria using a 2D MOF nanozyme-amplified electrochemical detector","volume":"93","author":"Hu","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.ymeth.2026.01.006_b0760","series-title":"Ce-Based MOF nanozyme with oxidase-like activity for sensitive colorimetric detection of glutathione in periodontitis","author":"Dang","year":"2025"},{"key":"10.1016\/j.ymeth.2026.01.006_b0765","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2023.133955","article-title":"Flexible screen-printed electrochemical platform to detect hydrogen peroxide for the indication of periodontal disease","volume":"390","author":"Wang","year":"2023","journal-title":"Sens. Actuators B"},{"key":"10.1016\/j.ymeth.2026.01.006_b0770","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.cej.2018.10.044","article-title":"Controllable synthesis of highly monodispersed nanoscale Fe-soc-MOF and the construction of Fe-soc-MOF@ polypyrrole core-shell nanohybrids for cancer therapy","volume":"358","author":"Cai","year":"2019","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0775","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2019.122175","article-title":"Tailored synthesis of hollow MOF\/polydopamine Janus nanoparticles for synergistic multi-drug chemo-photothermal therapy","volume":"378","author":"Li","year":"2019","journal-title":"Chem. Eng. J."},{"issue":"32","key":"10.1016\/j.ymeth.2026.01.006_b0780","doi-asserted-by":"crossref","first-page":"13466","DOI":"10.1039\/D3NR02662K","article-title":"Early-stage oral cancer diagnosis by artificial intelligence-based SERS using Ag NWs@ ZIF core\u2013shell nanochains","volume":"15","author":"Xie","year":"2023","journal-title":"Nanoscale"},{"key":"10.1016\/j.ymeth.2026.01.006_b0785","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.141444","article-title":"Hierarchical ensembles of FeCo metal-organic frameworks reinforced nickel foam as an impedimetric sensor for detection of IL-1RA in human samples","volume":"458","author":"Vijayaraghavan","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0790","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3390\/nano15030209","article-title":"Use of Antimicrobial Nanoparticles for the Management of Dental Diseases","volume":"15","author":"Yin","year":"2025","journal-title":"Nanomaterials"},{"issue":"37","key":"10.1016\/j.ymeth.2026.01.006_b0795","article-title":"Nanoparticles of metal\u2010organic frameworks: on the road to in vivo efficacy in biomedicine","volume":"30","author":"Simon-Yarza","year":"2018","journal-title":"Adv. Mater."},{"issue":"6","key":"10.1016\/j.ymeth.2026.01.006_b0800","first-page":"602","article-title":"Research progress on metal-organic frameworks in dental medicine","volume":"29","author":"Jian","year":"2025","journal-title":"Chinese Journal of Oral Implantology"},{"key":"10.1016\/j.ymeth.2026.01.006_b0805","doi-asserted-by":"crossref","first-page":"6185","DOI":"10.2147\/IJN.S434917","article-title":"Nano-photosensitizer directed targeted phototherapy effective against oral cancer in animal model","author":"Yu","year":"2023","journal-title":"Int. J. Nanomed."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0810","doi-asserted-by":"crossref","first-page":"441","DOI":"10.31557\/apjcb.2024.9.3.441-443","article-title":"Targeted Oral Therapy: Utilization of Metal-Organic Frameworks","volume":"9","author":"Shaji","year":"2024","journal-title":"Asian Pacific Journal of Cancer Biology"},{"issue":"11","key":"10.1016\/j.ymeth.2026.01.006_b0815","doi-asserted-by":"crossref","first-page":"3119","DOI":"10.1039\/D4QI00523F","article-title":"Surface functionalization of metal\u2013organic framework nanoparticle for overcoming biological barrier in cancer therapy","volume":"11","author":"Oh","year":"2024","journal-title":"Inorg. Chem. Front."},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0820","first-page":"1837","article-title":"Exploring metal organic frameworks for efficient drug delivery: A bibliometric review","volume":"43","author":"Dutta","year":"2025","journal-title":"Sigma"},{"key":"10.1016\/j.ymeth.2026.01.006_b0825","article-title":"Metal-organic frameworks in sample preparation for clinical applications\u2013A review","volume":"344296","author":"Pacheco-Fern\u00e1ndez","year":"2025","journal-title":"Anal. Chim. Acta"},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0830","first-page":"368","volume":"29","author":"Shahi","year":"2019","journal-title":"A review on potential toxicity of dental material and screening their biocompatibility, Toxicology mechanisms and methods"},{"key":"10.1016\/j.ymeth.2026.01.006_b0835","first-page":"125","article-title":"Nanoparticles in dentistry, their applications, and biocompatibility","volume":"24","author":"Oyar","year":"2014","journal-title":"J Dent Fac Atat\u00fcrk Uni"},{"issue":"12","key":"10.1016\/j.ymeth.2026.01.006_b0840","doi-asserted-by":"crossref","first-page":"3167","DOI":"10.3390\/ma14123167","article-title":"Recent advances in the development of antimicrobial and antifouling biocompatible materials for dental applications","volume":"14","author":"Ramburrun","year":"2021","journal-title":"Materials"},{"issue":"8","key":"10.1016\/j.ymeth.2026.01.006_b0845","doi-asserted-by":"crossref","first-page":"3241","DOI":"10.1002\/jbm.b.34661","article-title":"Development of novel surface coating composed of MDPB and MPC with dual functionality of antibacterial activity and protein repellency","volume":"108","author":"Thongthai","year":"2020","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0850","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.sdentj.2023.08.013","article-title":"Local and systemic adverse effects of nanoparticles incorporated in dental materials-a critical review","volume":"36","author":"Karunakaran","year":"2024","journal-title":"The Saudi dental journal"},{"issue":"8","key":"10.1016\/j.ymeth.2026.01.006_b0855","doi-asserted-by":"crossref","first-page":"7064","DOI":"10.1021\/acsnano.2c12488","article-title":"Review of antimicrobial nanocoatings in medicine and dentistry: mechanisms of action, biocompatibility performance, safety, and benefits compared to antibiotics","volume":"17","author":"Butler","year":"2023","journal-title":"ACS Nano"},{"issue":"12","key":"10.1016\/j.ymeth.2026.01.006_b0860","doi-asserted-by":"crossref","first-page":"927","DOI":"10.3390\/nano15120927","article-title":"Synthesis, Characterization, and Toxicity Evaluation of Size-Dependent Iron-Based Metal\u2013Organic Frameworks","volume":"15","author":"Liu","year":"2025","journal-title":"Nanomaterials"},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0865","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s40496-023-00358-9","article-title":"A review on biocompatibility of dental restorative and reconstruction materials","volume":"11","author":"Paqu\u00e9","year":"2024","journal-title":"Curr. Oral Health Rep."},{"key":"10.1016\/j.ymeth.2026.01.006_b0870","article-title":"Advances in metal-organic framework-based drug delivery systems","volume":"125380","author":"Khulood","year":"2025","journal-title":"Int. J. Pharm."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b0875","doi-asserted-by":"crossref","DOI":"10.1016\/j.matt.2025.101958","article-title":"Guiding the rational design of biocompatible metal-organic frameworks for drug delivery","volume":"8","author":"Menon","year":"2025","journal-title":"Matter"},{"issue":"11","key":"10.1016\/j.ymeth.2026.01.006_b0880","article-title":"Identifying differing intracellular cargo release mechanisms by monitoring in vitro drug delivery from MOFs in real time","volume":"1","author":"Markopoulou","year":"2020","journal-title":"Cell Rep. Phys. Sci."},{"issue":"11","key":"10.1016\/j.ymeth.2026.01.006_b0885","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/s42256-020-00249-z","article-title":"Prediction of water stability of metal\u2013organic frameworks using machine learning","volume":"2","author":"Batra","year":"2020","journal-title":"Nat. Mach. Intell."},{"issue":"37","key":"10.1016\/j.ymeth.2026.01.006_b0890","doi-asserted-by":"crossref","first-page":"15427","DOI":"10.1021\/jacs.1c07875","article-title":"2D MOF periodontitis photodynamic ion therapy","volume":"143","author":"Li","year":"2021","journal-title":"J. Am. Chem. Soc."},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b0895","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1039\/D1SC04112F","article-title":"Cracking the immune fingerprint of metal\u2013organic frameworks","volume":"13","author":"Hidalgo","year":"2022","journal-title":"Chem. Sci."},{"key":"10.1016\/j.ymeth.2026.01.006_b0900","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2023.144400","article-title":"Mitigating metal-organic framework (MOF) toxicity for biomedical applications","volume":"471","author":"Wi\u015bniewska","year":"2023","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b0905","article-title":"Multiscale Profiling of Nanoscale Metal\u2010Organic Framework Biocompatibility and Immune Interactions","author":"Zhuang","year":"2025","journal-title":"Adv. Healthc. Mater."},{"issue":"12","key":"10.1016\/j.ymeth.2026.01.006_b0910","doi-asserted-by":"crossref","first-page":"4151","DOI":"10.1039\/D3BM00271C","article-title":"Immunotoxicity of metal and metal oxide nanoparticles: from toxic mechanisms to metabolism and outcomes","volume":"11","author":"Bi","year":"2023","journal-title":"Biomater. Sci."},{"issue":"11","key":"10.1016\/j.ymeth.2026.01.006_b0915","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1038\/s41577-024-01040-6","article-title":"A guide to adaptive immune memory","volume":"24","author":"Lam","year":"2024","journal-title":"Nat. Rev. Immunol."},{"issue":"29","key":"10.1016\/j.ymeth.2026.01.006_b0920","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202501809","article-title":"Multiscale Profiling of Nanoscale Metal\u2010Organic Framework Biocompatibility and Immune Interactions","volume":"14","author":"Zhuang","year":"2025","journal-title":"Adv. Healthc. Mater."},{"issue":"9","key":"10.1016\/j.ymeth.2026.01.006_b0925","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.dental.2023.06.007","article-title":"Evaluation of physical\/mechanical properties of an experimental dental composite modified with a zirconium-based metal-organic framework (MOF) as an innovative dental filler","volume":"39","author":"Shekofteh","year":"2023","journal-title":"Dent. Mater."},{"key":"10.1016\/j.ymeth.2026.01.006_b0930","article-title":"Evaluation of Antibacterial, Physicochemical, and Mechanical Properties of a Pit and Fissure Material Containing Silver Nanoparticles Attached to Metal-organic Framework","author":"Mokhtari","year":"2025","journal-title":"Journal of Dentistry (Articles in Press)"},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b0935","article-title":"Metal-organic frameworks in oral drug delivery","volume":"19","author":"Raza","year":"2024","journal-title":"Asian J. Pharm. Sci."},{"key":"10.1016\/j.ymeth.2026.01.006_b0940","article-title":"Sustainable metal-organic frameworks (MOFs) for drug delivery systems","volume":"35","author":"Rabiee","year":"2023","journal-title":"Mater. Today Commun."},{"issue":"2","key":"10.1016\/j.ymeth.2026.01.006_b0945","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.gce.2023.07.004","article-title":"The stability of MOFs in aqueous solutions\u2014research progress and prospects","volume":"5","author":"An","year":"2024","journal-title":"Green Chem. Eng."},{"issue":"19","key":"10.1016\/j.ymeth.2026.01.006_b0950","doi-asserted-by":"crossref","first-page":"10611","DOI":"10.3390\/app131910611","article-title":"Biodegradable polymer composites of metal organic framework-5 (MOF-5) for the efficient and sustained delivery of cephalexin and metronidazole","volume":"13","author":"Anim","year":"2023","journal-title":"Appl. Sci."},{"issue":"6","key":"10.1016\/j.ymeth.2026.01.006_b0955","doi-asserted-by":"crossref","first-page":"3189","DOI":"10.3390\/app15063189","article-title":"Enhancement of EPR effect for passive tumor targeting: current status and future perspectives","volume":"15","author":"Vagena","year":"2025","journal-title":"Appl. Sci."},{"issue":"7","key":"10.1016\/j.ymeth.2026.01.006_b0960","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1002\/jso.22102","article-title":"Targeting integrins and enhanced permeability and retention (EPR) effect for optical imaging of oral cancer","volume":"105","author":"Keereweer","year":"2012","journal-title":"J. Surg. Oncol."},{"key":"10.1016\/j.ymeth.2026.01.006_b0965","doi-asserted-by":"crossref","DOI":"10.1021\/acs.jpcc.5c06713","article-title":"Guest Molecules Release from MOF-808 and MOF-Based Hydrogel: An EPR Study","author":"Yazikova","year":"2025","journal-title":"J. Phys. Chem. C"},{"issue":"1","key":"10.1016\/j.ymeth.2026.01.006_b0970","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1186\/s12951-024-02555-9","article-title":"Dynamic hydrogel\u2013metal\u2013organic framework system promotes bone regeneration in periodontitis through controlled drug delivery","volume":"22","author":"Luo","year":"2024","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.ymeth.2026.01.006_b0975","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.ijbiomac.2018.07.181","article-title":"Carboxymethylcellulose capsulated Cu-based metal-organic framework-drug nanohybrid as a pH-sensitive nanocomposite for ibuprofen oral delivery","volume":"119","author":"Javanbakht","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"issue":"8","key":"10.1016\/j.ymeth.2026.01.006_b0980","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1002\/cnma.202000221","article-title":"Zn\u2010MOF\u201074 as pH\u2010responsive drug\u2010delivery system of arsenic trioxide","volume":"6","author":"Schnabel","year":"2020","journal-title":"ChemNanoMat"},{"key":"10.1016\/j.ymeth.2026.01.006_b0985","doi-asserted-by":"crossref","first-page":"628","DOI":"10.3389\/fbioe.2020.00628","article-title":"Microporous frameworks as promising platforms for antibacterial strategies against oral diseases","volume":"8","author":"Wan","year":"2020","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"14","key":"10.1016\/j.ymeth.2026.01.006_b0990","article-title":"Multi\u2010Mechanism Antibacterial Strategies Enabled by Synergistic Activity of Metal\u2013Organic Framework\u2010Based Nanosystem for Infected Tissue Regeneration","volume":"19","author":"Xie","year":"2023","journal-title":"Small"},{"issue":"43","key":"10.1016\/j.ymeth.2026.01.006_b0995","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.201904828","article-title":"Engineering a nanoscale Al\u2010MOF\u2010armored antigen carried by a \u201ctrojan horse\u201d\u2010like platform for oral vaccination to induce potent and long\u2010lasting immunity","volume":"29","author":"Miao","year":"2019","journal-title":"Adv. Funct. Mater."},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b1000","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1002\/nano.202100258","article-title":"Applications of metal\u2013organic frameworks for oral delivery systems","volume":"3","author":"Jiao","year":"2022","journal-title":"Nano Select"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b1005","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1039\/C6RE00107F","article-title":"Towards scalable and controlled synthesis of metal\u2013organic framework materials using continuous flow reactors","volume":"1","author":"Dunne","year":"2016","journal-title":"React. Chem. Eng."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b1010","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3390\/nano15030205","article-title":"Applications of MOF-Based Nanocomposites in Heat Exchangers: Innovations, Challenges, and Future Directions","volume":"15","author":"Nadeem","year":"2025","journal-title":"Nanomaterials"},{"key":"10.1016\/j.ymeth.2026.01.006_b1015","article-title":"Metal Oxide Functionalized Nanoparticles for the Treatment of Bacterial Infection: Synthesis","author":"Prasad","year":"2025","journal-title":"Characterization, and Therapeutic Applications"},{"key":"10.1016\/j.ymeth.2026.01.006_b1020","doi-asserted-by":"crossref","DOI":"10.1016\/j.jddst.2020.101879","article-title":"Carbosilane dendrimers: Drug and gene delivery applications","volume":"59","author":"Rabiee","year":"2020","journal-title":"J. Drug Delivery Sci. Technol."},{"key":"10.1016\/j.ymeth.2026.01.006_b1025","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.cej.2015.02.094","article-title":"ZIF-8: A comparison of synthesis methods","volume":"271","author":"Lee","year":"2015","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.ymeth.2026.01.006_b1030","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.biortech.2019.02.041","article-title":"Zirconium based metal-organic framework in-situ assisted hydrothermal pretreatment and enzymatic hydrolysis of Platanus X acerifolia exfoliating bark for bioethanol production","volume":"280","author":"Ahmed","year":"2019","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ymeth.2026.01.006_b1035","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.biomaterials.2015.12.018","article-title":"Folate-targeted pH-responsive calcium zoledronate nanoscale metal-organic frameworks: turning a bone antiresorptive agent into an anticancer therapeutic","volume":"82","author":"Au","year":"2016","journal-title":"Biomaterials"},{"issue":"7","key":"10.1016\/j.ymeth.2026.01.006_b1040","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.3390\/molecules24071211","article-title":"In vitro toxicity study of a porous iron (III) metal\u2012organic framework","volume":"24","author":"Chen","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.ymeth.2026.01.006_b1045","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.dyepig.2016.07.007","article-title":"Diketopyrrolopyrrole-based oligomers accessed via sequential CH activated coupling for fullerene-free organic photovoltaics","volume":"134","author":"Liu","year":"2016","journal-title":"Dyes Pigm."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b1050","doi-asserted-by":"crossref","DOI":"10.1149\/1945-7111\/abec97","article-title":"Metal organic framework based nanomaterials for electrochemical sensing of toxic heavy metal ions: progress and their prospects","volume":"168","author":"Devaraj","year":"2021","journal-title":"J. Electrochem. Soc."},{"issue":"91","key":"10.1016\/j.ymeth.2026.01.006_b1055","doi-asserted-by":"crossref","first-page":"12098","DOI":"10.1039\/D1CC05157A","article-title":"Metal\u2013organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics","volume":"57","author":"Tong","year":"2021","journal-title":"Chem. Commun."},{"key":"10.1016\/j.ymeth.2026.01.006_b1060","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.msec.2017.03.114","article-title":"Iodine-loaded metal organic framework as growth-triggered antimicrobial agent","volume":"76","author":"Au-Duong","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.ymeth.2026.01.006_b1065","first-page":"1","article-title":"Cu-BTC metal\u2013organic framework as a biocompatible nanoporous carrier for chlorhexidine antibacterial agent","author":"Soltani","year":"2022","journal-title":"J. Biol. Inorg. Chem."},{"issue":"7","key":"10.1016\/j.ymeth.2026.01.006_b1070","first-page":"734","article-title":"Preparation of a novel Ti-metal organic framework porous nanofiber polymer as an efficient dental nano-coating: physicochemical and mechanical properties","volume":"60","author":"Azizabadi","year":"2021","journal-title":"Polym.-Plast. Technol. Mater."},{"key":"10.1016\/j.ymeth.2026.01.006_b1075","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.134184","article-title":"Synthesis of various dimensional metal organic frameworks (MOFs) and their hybrid composites for emerging applications\u2013a review","volume":"298","author":"Annamalai","year":"2022","journal-title":"Chemosphere"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b1080","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1021\/acs.langmuir.1c03073","article-title":"Biomimetic Growth of Metal\u2013Organic Frameworks for the Stabilization of the Dentin Matrix and Control of Collagenolysis","volume":"38","author":"Bim-Junior","year":"2022","journal-title":"Langmuir"},{"key":"10.1016\/j.ymeth.2026.01.006_b1085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40064-016-1735-2","article-title":"Management of peri-implantitis: A systematic review, 2010\u20132015","volume":"5","author":"Mahato","year":"2016","journal-title":"Springerplus"},{"issue":"7","key":"10.1016\/j.ymeth.2026.01.006_b1090","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.3390\/nano13071247","article-title":"Nanotechnology-Based Diagnostics for Diseases Prevalent in Developing Countries: Current Advances in Point-of-Care Tests","volume":"13","author":"Thwala","year":"2023","journal-title":"Nanomaterials"},{"key":"10.1016\/j.ymeth.2026.01.006_b1095","doi-asserted-by":"crossref","DOI":"10.1002\/tcr.202500146","article-title":"Carbon Quantum Dot\u2010Encapsulated Metal\u2013Organic Framework Hybrids as Multifunctional Fluorescent Sensors for Oral Disease Biomarker Detection","author":"Ghahramani","year":"2025","journal-title":"Chem. Rec."},{"key":"10.1016\/j.ymeth.2026.01.006_b1100","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/978-3-030-06115-9_24","article-title":"Application of nanoparticles in treating periodontitis: Preclinical and clinical overview","author":"Mercado","year":"2019","journal-title":"Surface Modification of Nanoparticles for Targeted Drug Delivery"},{"key":"10.1016\/j.ymeth.2026.01.006_b1105","doi-asserted-by":"crossref","unstructured":"L.X. Kong, Z. Peng, S.D. Li, P.M. Bartold, Nanotechnology and its role in the management of periodontal diseases, PERIODONTOLOGY 2000 40(1) (2006) 184.","DOI":"10.1111\/j.1600-0757.2005.00143.x"},{"issue":"4","key":"10.1016\/j.ymeth.2026.01.006_b1110","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1080\/10408347.2024.2315112","article-title":"Advances in electrochemical biosensors for the detection of common oral diseases","volume":"55","author":"Liu","year":"2025","journal-title":"Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.ymeth.2026.01.006_b1115","doi-asserted-by":"crossref","first-page":"802","DOI":"10.3389\/fphar.2018.00802","article-title":"Advantages and Limitations of Current Techniques for Analyzing the Biodistribution of Nanoparticles","volume":"9","author":"Arms","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"5","key":"10.1016\/j.ymeth.2026.01.006_b1120","doi-asserted-by":"crossref","first-page":"864","DOI":"10.3390\/polym14050864","article-title":"Polymeric dental nanomaterials: Antimicrobial action","volume":"14","author":"Yudaev","year":"2022","journal-title":"Polymers"},{"key":"10.1016\/j.ymeth.2026.01.006_b1125","series-title":"Comprehensive preventive dentistry","author":"Limeback","year":"2012"},{"issue":"8","key":"10.1016\/j.ymeth.2026.01.006_b1130","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1016\/j.apsb.2021.03.019","article-title":"Metal-organic frameworks for advanced drug delivery","volume":"11","author":"He","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.ymeth.2026.01.006_b1135","doi-asserted-by":"crossref","DOI":"10.1016\/j.rechem.2024.101414","article-title":"Metal organic frameworks in biomedicine: Innovations in drug delivery","volume":"7","author":"Benny","year":"2024","journal-title":"Results Chem."},{"issue":"3","key":"10.1016\/j.ymeth.2026.01.006_b1140","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3390\/jfb16030083","article-title":"Cu-MOF-Decorated 3D-Printed Scaffolds for Infection Control and Bone Regeneration","volume":"16","author":"Zhu","year":"2025","journal-title":"Journal of Functional Biomaterials"},{"issue":"12","key":"10.1016\/j.ymeth.2026.01.006_b1145","doi-asserted-by":"crossref","DOI":"10.1002\/slct.202404898","article-title":"Advances in Metal\u2010Organic Frameworks for Use in 3D Printing Techniques","volume":"10","author":"Bhosale","year":"2025","journal-title":"ChemistrySelect"},{"key":"10.1016\/j.ymeth.2026.01.006_b1150","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2025.1645657","article-title":"Functionalized Metal-Organic Framework (MOF) and MOF-Derived Materials for Bone Regeneration Application","volume":"13","author":"Fan","year":"2025","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"2","key":"10.1016\/j.ymeth.2026.01.006_b1155","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1177\/09506608241299174","article-title":"3D Engineered scaffolds of conjugated polymers\/metal organic frameworks for biomedical applications","volume":"70","author":"Sharifabad","year":"2025","journal-title":"Int. Mater. Rev."},{"key":"10.1016\/j.ymeth.2026.01.006_b1160","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2021.101182","article-title":"Bioinspired adhesive and tumor microenvironment responsive nanoMOFs assembled 3D-printed scaffold for anti-tumor therapy and bone regeneration","volume":"39","author":"Jiang","year":"2021","journal-title":"Nano Today"},{"issue":"2","key":"10.1016\/j.ymeth.2026.01.006_b1165","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/ab5ae3","article-title":"3D printing of metal-organic framework nanosheets-structured scaffolds with tumor therapy and bone construction","volume":"12","author":"Dang","year":"2020","journal-title":"Biofabrication"},{"key":"10.1016\/j.ymeth.2026.01.006_b1170","article-title":"Nanoparticle-based drug delivery system for Oral Cancer: Mechanism, challenges, and therapeutic potential","volume":"102068","author":"Hasan","year":"2025","journal-title":"Results Chem."}],"container-title":["Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104620232600006X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104620232600006X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T21:12:51Z","timestamp":1770671571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S104620232600006X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":234,"alternative-id":["S104620232600006X"],"URL":"https:\/\/doi.org\/10.1016\/j.ymeth.2026.01.006","relation":{},"ISSN":["1046-2023"],"issn-type":[{"value":"1046-2023","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The clinical potential and limitations of metal-organic frameworks (MOFs) in dentistry","name":"articletitle","label":"Article Title"},{"value":"Methods","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ymeth.2026.01.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}