{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T17:29:08Z","timestamp":1792517348976,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Genetics and Metabolism"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.ymgme.2008.12.001","type":"journal-article","created":{"date-parts":[[2009,1,15]],"date-time":"2009-01-15T09:26:41Z","timestamp":1232011601000},"page":"113-120","source":"Crossref","is-referenced-by-count":21,"title":["Patients with Gaucher disease living in England show a high prevalence of vitamin D insufficiency with correlation to osteodensitometry"],"prefix":"10.1016","volume":"96","author":[{"given":"P.","family":"Mikosch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Stettner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.B.","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.A.","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymgme.2008.12.001_bib1","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1136\/bmj.327.7413.462","article-title":"Treatment of lysosomal storage disorders","volume":"327","author":"Mehta","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.ymgme.2008.12.001_bib2","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/j.1365-2141.2007.06701.x","article-title":"Recommendations for the management of the haematological and onco-haematological aspects of Gaucher disease","volume":"138","author":"Hughes","year":"2007","journal-title":"Br. J. Haematol."},{"issue":"Suppl 1","key":"10.1016\/j.ymgme.2008.12.001_bib3","first-page":"A2","article-title":"Skeletal aspects of Gaucher disease: a review","volume":"75","author":"Wenstrup","year":"2003","journal-title":"Br. J. Radiol."},{"key":"10.1016\/j.ymgme.2008.12.001_bib4","first-page":"205","article-title":"Cytokines in Gaucher\u2019s disease","volume":"10","author":"Barak","year":"1999","journal-title":"Eur. Cytokine Netw."},{"key":"10.1016\/j.ymgme.2008.12.001_bib5","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ymgme.2008.12.001_bib6","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1210\/jc.86.3.1212","article-title":"A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial","volume":"86","author":"Lips","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ymgme.2008.12.001_bib7","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1185\/030079907X219562","article-title":"Prevalence of vitamin D inadequacy in European postmenopausal women","volume":"23","author":"Bruy\u00e8re","year":"2007","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.ymgme.2008.12.001_bib8","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1093\/ajcn\/85.3.860","article-title":"Hypovitaminosis D in British adults at the age of 45y: nationwide cohort study of dietary and lifestyle predictors","volume":"85","author":"Hypp\u00f6nen","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib9","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/s00198-002-1338-3","article-title":"In a population study, can parathyroid hormone aid the definition of adequate vitamin D status? A study of people aged 65 years and over from the British National Diet and Nutrition Survey","volume":"14","author":"Bates","year":"2003","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.ymgme.2008.12.001_bib10","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1024\/0300-9831.76.5.307","article-title":"Vitamin D status in patients with osteopenia or osteoporosis\u2014an audit of an endocrine clinic","volume":"76","author":"Kocjan","year":"2006","journal-title":"Int. J. Vitam. Nutr. Res."},{"key":"10.1016\/j.ymgme.2008.12.001_bib11","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.bone.2004.02.003","article-title":"The relationship between vitamin D and parathyroid hormone: calcium homeostasis, bone turnover, and bone mineral density in postmenopausal women with established osteoporosis","volume":"35","author":"Sahota","year":"2004","journal-title":"Bone"},{"key":"10.1016\/j.ymgme.2008.12.001_bib12","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1185\/030079906X80369","article-title":"Prevalence of vitamin D inadequacy in patients attending a metabolic bone clinic in Medway","volume":"22","author":"Ryan","year":"2006","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.ymgme.2008.12.001_bib13","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1185\/030079906X80332","article-title":"Prevalence of vitamin D inadequacy in Belfast following fragility fracture","volume":"22","author":"Beringer","year":"2006","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.ymgme.2008.12.001_bib14","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1258\/000456306778904614","article-title":"Vitamin D concentrations in an UK inner-city multicultural outpatient population","volume":"43","author":"Ford","year":"2006","journal-title":"Ann. Clin. Biochem."},{"key":"10.1016\/j.ymgme.2008.12.001_bib15","first-page":"31","article-title":"Body composition and bone metabolism in young Gaucher disease type I patients treated with imiglucerase","volume":"13","author":"Parisi","year":"2008","journal-title":"Eur. J. Med. Res."},{"key":"10.1016\/j.ymgme.2008.12.001_bib16","series-title":"National Diet and Nutrition Survey: Adults Aged 19 to 64 Years","volume":"vol. 3","author":"Henderson","year":"2003"},{"key":"10.1016\/j.ymgme.2008.12.001_bib17","series-title":"National Diet and Nutrition Survey: People Aged 65 Years and Over","volume":"vol. 1","author":"Finch","year":"1998"},{"key":"10.1016\/j.ymgme.2008.12.001_bib18","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1007\/s00198-005-1867-7","article-title":"Estimates of optimal vitamin D status","volume":"10","author":"Dawson-Hughes","year":"2005","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.ymgme.2008.12.001_bib19","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/jn\/135.2.317","article-title":"Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D","volume":"135","author":"Hollis","year":"2005","journal-title":"J. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib20","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.jsbmb.2006.12.076","article-title":"Vitamin D status and nutrition in Europe and Asia","volume":"103","author":"Lips","year":"2007","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.ymgme.2008.12.001_bib21","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1365-2133.1984.tb04731.x","article-title":"Cutaneous manifestations of Gaucher disease","volume":"111","author":"Goldblatt","year":"1984","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.ymgme.2008.12.001_bib22","first-page":"301","article-title":"In vivo threshold for cutaneous synthesis of vitamin D3","volume":"114","author":"Matsuoka","year":"1989","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.ymgme.2008.12.001_bib23","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1079\/BJN2003837","article-title":"Vitamin D in preventive medicine: are we ignoring the evidence?","volume":"89","author":"Zittermann","year":"2003","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib24","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/ajcn\/85.3.649","article-title":"The urgent need to recommend an intake of vitamin D that is effective","volume":"85","author":"Vieth","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.maturitas.2007.05.002","article-title":"Vitamin D and its implications for musculoskeletal health in women: an update","volume":"58","author":"P\u00e9rez-L\u00f3pez","year":"2007","journal-title":"Maturitas"},{"key":"10.1016\/j.ymgme.2008.12.001_bib26","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1080\/07315724.2003.10719287","article-title":"Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D","volume":"22","author":"Heaney","year":"2003","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jsbmb.2005.06.020","article-title":"The vitamin D requirement in health and disease","volume":"97","author":"Heaney","year":"2005","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.ymgme.2008.12.001_bib28","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1056\/NEJM200502033520521","article-title":"Normal serum vitamin D levels","volume":"352","author":"Hollis","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ymgme.2008.12.001_bib29","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1007\/s00198-005-1910-8","article-title":"Vitamin D, parathyroid hormone levels and bone mineral density in community-dwelling older women: the Rancho Bernardo Study","volume":"16","author":"von M\u00fchlen","year":"2005","journal-title":"Osteoporos Int."},{"key":"10.1016\/j.ymgme.2008.12.001_bib30","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00198-003-1566-1","article-title":"Prevalence and seasonal variation of hypovitaminosis D and its relationship to bone metabolism in community dwelling postmenopausal Hungarian women","volume":"15","author":"Bhattoa","year":"2004","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.ymgme.2008.12.001_bib31","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1046\/j.1365-2362.2003.01127.x","article-title":"Austrian study group on normative values of bone metabolism, assessment of vitamin D and calcium status in healthy adult Austrians","volume":"33","author":"Kudlacek","year":"2003","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.ymgme.2008.12.001_bib32","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1079\/PHN2005837","article-title":"Vitamin D status of 51\u201375-year-old Irish women: its determinants and impact on biochemical indices of bone turnover","volume":"9","author":"Hill","year":"2006","journal-title":"Public Health Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib33","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1038\/sj.ejcn.1602825","article-title":"Vitamin D status and health correlates among German adults","volume":"62","author":"Hintzpeter","year":"2008","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib34","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/1471-2458-7-64","article-title":"Vitamin D inadequacy in Belgian postmenopausal osteoporotic women","volume":"7","author":"Neuprez","year":"2007","journal-title":"BMC Public Health"},{"key":"10.1016\/j.ymgme.2008.12.001_bib35","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1046\/j.1532-5415.2001.49236.x","article-title":"Seasonal variations in serum levels of 25-OHhydroxyvitamin D and parathyroid hormone but no detectable change in femoral neck bone density in an older population with outdoor exposure","volume":"49","author":"Melin","year":"2001","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.ymgme.2008.12.001_bib36","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1210\/jc.2006-2079","article-title":"A Hip and nonvertebral fracture prediction in nursing home patients: role of bone ultrasound and bone marker measurements","volume":"92","author":"Dobnig","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ymgme.2008.12.001_bib37","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s00198-006-0069-2","article-title":"High Prevalence of vitamin D deficiency, secondary hyperparathyroidism and generalized bone pain in Turkish immigrants in Germany: identification of risk factors","volume":"17","author":"Erkal","year":"2006","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.ymgme.2008.12.001_bib38","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/sj.ejcn.1602753","article-title":"Pakistani immigrant children and adults in Denmark have severely low vitamin D status","volume":"62","author":"Andersen","year":"2008","journal-title":"Eur. J. Clin. Nutr."},{"issue":"Suppl. 5","key":"10.1016\/j.ymgme.2008.12.001_bib39","first-page":"97","article-title":"The prevalence of hypovitaminosis D among US adults: data from the NHANES III","volume":"15","author":"Zadshir","year":"2005","journal-title":"Ethn. Dis."},{"key":"10.1016\/j.ymgme.2008.12.001_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.amjopharm.2007.03.005","article-title":"Prevalence of vitamin D insufficiency in elderly ambulatory outpatients in Denver, Colorado","volume":"5","author":"Linnebur","year":"2007","journal-title":"Am. J. Geriatr. Pharmacother."},{"key":"10.1016\/j.ymgme.2008.12.001_bib41","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1210\/jc.2006-2250","article-title":"Low vitamin D status despite abundant sun exposure","volume":"92","author":"Binkley","year":"2007","journal-title":"J. Clin. Endorinol. Metab."},{"key":"10.1016\/j.ymgme.2008.12.001_bib42","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1007\/s00774-006-0746-4","article-title":"Vitamin D deficiency in the elderly in Athens, Greece","volume":"25","author":"Papapetrou","year":"2007","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.ymgme.2008.12.001_bib43","doi-asserted-by":"crossref","first-page":"3086","DOI":"10.1210\/jc.86.7.3086","article-title":"Vitamin D status and redefining serum parathyroid hormone reference range in the elderly","volume":"86","author":"Souberbielle","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ymgme.2008.12.001_bib44","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1093\/ajcn\/84.3.616","article-title":"Low serum concentrations of 25-hydroxyvitamin D in older persons and risk of nursing home admission","volume":"84","author":"Visser","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib45","doi-asserted-by":"crossref","first-page":"4615","DOI":"10.1210\/jc.2007-1279","article-title":"Serum 25-hydroxyvitamin D measurement in a large population survey with statistical harmonization of assay variation to an international standard","volume":"92","author":"Hypp\u00f6nen","year":"2007","journal-title":"J. Clin. Endocrin. Metab."},{"key":"10.1016\/j.ymgme.2008.12.001_bib46","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1038\/sj.ejcn.1601275","article-title":"Wintertime vitamin D insufficiency is common in young Canadian women and their vitamin D intake does not prevent it","volume":"55","author":"Vieth","year":"2001","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib47","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/sj.ejcn.1602550","article-title":"Vitamin D fortification of milk products does not resolve hypovitaminosis D in young Finnish men","volume":"61","author":"V\u00e4lim\u00e4ki","year":"2007","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib48","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1079\/PHN2004605","article-title":"Vitamin D status in a rural population of northern Norway with high fish liver consumption","volume":"7","author":"Brustad","year":"2004","journal-title":"Public Health Nutr."},{"key":"10.1016\/j.ymgme.2008.12.001_bib49","first-page":"94","article-title":"Benefits and requirements of vitamin D for optimal health: a review","volume":"10","author":"Grant","year":"2005","journal-title":"Altern. Med. Rev."}],"container-title":["Molecular Genetics and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096719208004502?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096719208004502?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T09:04:35Z","timestamp":1558083875000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096719208004502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S1096719208004502"],"URL":"https:\/\/doi.org\/10.1016\/j.ymgme.2008.12.001","relation":{},"ISSN":["1096-7192"],"issn-type":[{"value":"1096-7192","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}