{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T09:42:23Z","timestamp":1771062143303,"version":"3.50.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Genetics and Metabolism"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.ymgme.2023.107607","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T21:55:41Z","timestamp":1683755741000},"page":"107607","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["COVID-19 in inherited metabolic disorders: Clinical features and risk factors for disease severity"],"prefix":"10.1016","volume":"139","author":[{"given":"Ayca Burcu","family":"Kahraman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y\u0131lmaz","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u0131smet","family":"\u00c7\u0131k\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izzet","family":"Erdal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halil Tuna","family":"Akar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Dursun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015feg\u00fcl","family":"Tokatl\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serap","family":"Sivri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymgme.2023.107607_bb0005","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1186\/s12879-021-06536-3","article-title":"Mortality-related risk factors of COVID-19: a systematic review and meta-analysis of 42 studies and 423,117 patients","volume":"21","author":"Dessie","year":"2021","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.ymgme.2023.107607_bb0010","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/jimd.12348","article-title":"An international classification of inherited metabolic disorders (ICIMD)","volume":"44","author":"Ferreira","year":"2021","journal-title":"J. Inherit. Metab. Dis."},{"issue":"5","key":"10.1016\/j.ymgme.2023.107607_bb0015","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/jpc.14994","article-title":"First paediatric COVID-19 associated death in Italy","volume":"57","author":"Mercolini","year":"2021","journal-title":"J. Paediatr. Child Health."},{"key":"10.1016\/j.ymgme.2023.107607_bb0020","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1515\/jpem-2021-0067","article-title":"Invisible burden of COVID-19: enzyme replacement therapy disruptions","volume":"34","author":"Kahraman","year":"2021","journal-title":"J. Pediatr. Endocrinol. Metab."},{"key":"10.1016\/j.ymgme.2023.107607_bb0025","series-title":"Pros and Cons of Telemedicine for Inherited Metabolic Disorders in a Developing Country during the COVID-19 Pandemic Telemedicine and e-Health","author":"Ko\u00e7 Yeked\u00fcz","year":"2022"},{"key":"10.1016\/j.ymgme.2023.107607_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13023-022-02247-3","article-title":"One year of COVID-19: infection rates and symptoms in patients with inherited metabolic diseases followed by MetabERN","volume":"17","author":"Paneghetti","year":"2022","journal-title":"Orphan. J. Rare Dis."},{"key":"10.1016\/j.ymgme.2023.107607_bb0035","first-page":"1093","article-title":"Difference in clinical patterns between COVID-19","volume":"30","author":"Hasnat","year":"2021","journal-title":"Affected Childr. Adults Mymensingh Med. J."},{"key":"10.1016\/j.ymgme.2023.107607_bb0040","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/jimd.12572","article-title":"Impact of the SARS-CoV-2 pandemic on the health of individuals with intoxication-type metabolic diseases\u2014data from the E-IMD consortium","volume":"46","author":"M\u00fctze","year":"2023","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.ymgme.2023.107607_bb0045","series-title":"Living guidance for clinical management of COVID-19","year":"2021"},{"key":"10.1016\/j.ymgme.2023.107607_bb0050","series-title":"International Guidelines for Certification and Classification (Coding) of COVID-19 as Cause of Death","year":"2020"},{"key":"10.1016\/j.ymgme.2023.107607_bb0055","series-title":"Emergency Pre- Paredness and Response: Health Alert Network","author":"Centers for Disease Control and Prevention","year":"2020"},{"key":"10.1016\/j.ymgme.2023.107607_bb0060","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/jmv.26398","article-title":"A systematic review and meta-analysis of children with coronavirus disease 2019 (COVID-19)","volume":"93","author":"Cui","year":"2021","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.ymgme.2023.107607_bb0065","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1097\/MPG.0000000000003204","article-title":"Gastrointestinal perspective of coronavirus disease 2019 in children-an updated review","volume":"73","author":"Assa","year":"2021","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.1016\/j.ymgme.2023.107607_bb0070","first-page":"1","article-title":"Lysosomal storage diseases","volume":"4","author":"Platt","year":"2018","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.ymgme.2023.107607_bb0075","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.paed.2019.01.008","article-title":"Acute presentations of inherited metabolic disorders: investigation and initial management","volume":"29","author":"Ghosh","year":"2019","journal-title":"Paediatr. Child Health"},{"key":"10.1016\/j.ymgme.2023.107607_bb0080","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10545-013-9621-3","article-title":"Usefulness of biochemical parameters in decision-making on the start of emergency treatment in patients with propionic acidemia","volume":"37","author":"Zwickler","year":"2014","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.ymgme.2023.107607_bb0085","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s10545-011-9426-1","article-title":"Metabolic decompensation in methylmalonic aciduria: which biochemical parameters are discriminative?","volume":"35","author":"Zwickler","year":"2012","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.ymgme.2023.107607_bb0090","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/jimd.12370","article-title":"Guidelines for the diagnosis and management of methylmalonic acidaemia and propionic acidaemia: first revision","volume":"44","author":"Forny","year":"2021","journal-title":"J. Inherit. Metab. Dis."},{"issue":"1","key":"10.1016\/j.ymgme.2023.107607_bb0095","first-page":"e14938","volume":"64","author":"Zubarioglu","year":"2022","journal-title":"Inborn errors of metabolism and COVID-19: Evaluation of the metabolic outcome, Pediatr Int."},{"key":"10.1016\/j.ymgme.2023.107607_bb0100","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1002\/ajmg.a.62161","article-title":"Management of COVID-19 infection in organic acidemias","volume":"185","author":"Kaur","year":"2021","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.ymgme.2023.107607_bb0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13023-014-0130-8","article-title":"Proposed guidelines for the diagnosis and management of methylmalonic and propionic acidemia","volume":"9","author":"Baumgartner","year":"2014","journal-title":"Orphan. J. Rare Dis."},{"key":"10.1016\/j.ymgme.2023.107607_bb0110","doi-asserted-by":"crossref","DOI":"10.1097\/INF.0000000000003328","article-title":"How common is long COVID in children and adolescents?","volume":"40","author":"Zimmermann","year":"2021","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.ymgme.2023.107607_bb0115","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/ajmg.c.31883","article-title":"SARS-CoV-2 pandemic in the Brazilian community of rare diseases: a patient reported survey","author":"Schwartz","year":"2021","journal-title":"Am. J. Med. Genet. C: Semin. Med. Genet."},{"key":"10.1016\/j.ymgme.2023.107607_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13023-020-01619-x","article-title":"The impact of COVID-19 on rare metabolic patients and healthcare providers: results from two MetabERN surveys","volume":"15","author":"Lampe","year":"2020","journal-title":"Orphan. J. Rare Dis."},{"key":"10.1016\/j.ymgme.2023.107607_bb0125","article-title":"Risk factors for severe COVID-19 in children: a systematic review and meta-analysis","volume":"37","author":"Choi","year":"2022","journal-title":"Journal of Korean Medical Science"},{"key":"10.1016\/j.ymgme.2023.107607_bb0130","series-title":"Differences in Clinical and Imaging Presentation of Pediatric Patients with COVID-19 in Comparison with Adults Radiology: Cardiothoracic Imaging","volume":"Vol. 2","author":"Chen","year":"2020"},{"key":"10.1016\/j.ymgme.2023.107607_bb0135","series-title":"Epidemiology of COVID-19 among Children in China Pediatrics","volume":"Vol. 145","author":"Dong","year":"2020"},{"key":"10.1016\/j.ymgme.2023.107607_bb0140","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s12098-020-03322-y","article-title":"Pathophysiology of COVID-19: why children fare better than adults?","volume":"87","author":"Dhochak","year":"2020","journal-title":"Indian J. Pediatr."},{"key":"10.1016\/j.ymgme.2023.107607_bb0145","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1177\/0009922820966306","article-title":"Characteristics and Management of Children with COVID-19 in a tertiary Care Hospital in Turkey","volume":"60","author":"Yayla","year":"2021","journal-title":"Clin. Pediatr. (Phila)"},{"key":"10.1016\/j.ymgme.2023.107607_bb0150","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1093\/eurheartj\/ehac031","article-title":"Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus","volume":"43","author":"Raman","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ymgme.2023.107607_bb0155","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1111\/apa.15673","article-title":"Case report and systematic review suggest that children may experience similar long-term effects to adults after clinical COVID-19","volume":"110","author":"Ludvigsson","year":"2021","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.ymgme.2023.107607_bb0160","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.16420","article-title":"Incidence of multisystem inflammatory syndrome in children among US persons infected with SARS-CoV-2","volume":"4","author":"Payne","year":"2021","journal-title":"JAMA Netw. Open"},{"issue":"9","key":"10.1016\/j.ymgme.2023.107607_bib161","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1111\/apa.15985","article-title":"Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus 2","volume":"110","author":"Holm","year":"2021","journal-title":"Acta Paediatr"}],"container-title":["Molecular Genetics and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096719223002378?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096719223002378?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T23:53:50Z","timestamp":1761090830000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096719223002378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S1096719223002378"],"URL":"https:\/\/doi.org\/10.1016\/j.ymgme.2023.107607","relation":{},"ISSN":["1096-7192"],"issn-type":[{"value":"1096-7192","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"COVID-19 in inherited metabolic disorders: Clinical features and risk factors for disease severity","name":"articletitle","label":"Article Title"},{"value":"Molecular Genetics and Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ymgme.2023.107607","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"107607"}}