{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T16:24:20Z","timestamp":1779121460849,"version":"3.51.4"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T00:00:00Z","timestamp":1473811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Genetics and Metabolism Reports"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.ymgmr.2016.09.008","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T00:15:41Z","timestamp":1475540141000},"page":"31-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Alglucosidase alfa treatment alleviates liver disease in a mouse model of glycogen storage disease type IV"],"prefix":"10.1016","volume":"9","author":[{"given":"Haiqing","family":"Yi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengqin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Austin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya S","family":"Kishnani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baodong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymgmr.2016.09.008_bb0005","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1136\/adc.43.231.548","article-title":"Glycogen storage disease type IV, amylopectinosis","volume":"43","author":"Levin","year":"1968","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0010","series-title":"GeneReviews\u00ae [Internet]","first-page":"1993","article-title":"Glycogen storage disease type IV","author":"Magoulas","year":"2013"},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0015","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1212\/01.WNL.0000138429.11433.0D","article-title":"Clinical and genetic heterogeneity of branching enzyme deficiency (glycogenosis type IV)","volume":"63","author":"Bruno","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0020","doi-asserted-by":"crossref","first-page":"177","DOI":"10.2174\/1566524024605815","article-title":"The variable presentations of glycogen storage disease type IV: a review of clinical, enzymatic and molecular studies","volume":"2","author":"Moses","year":"2002","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0025","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1172\/JCI118517","article-title":"Hepatic and neuromuscular forms of glycogen storage disease type IV caused by mutations in the same glycogen-branching enzyme gene","volume":"97","author":"Bao","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0030","doi-asserted-by":"crossref","first-page":"60","DOI":"10.5009\/gnl.2009.3.1.60","article-title":"Living donor liver transplantation in a Korean child with glycogen storage disease type IV and a GBE1 mutation","volume":"3","author":"Ban","year":"2009","journal-title":"Gut Liver"},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0035","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1007\/BF02072093","article-title":"Liver-transplantation for type-I and type-IV glycogen-storage-disease","volume":"152","author":"Selby","year":"1993","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0040","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1399-3046.2007.00803.x","article-title":"Liver transplantation in children with glycogen storage disease: controversies and evaluation of the risk\/benefit of this procedure","volume":"12","author":"Davis","year":"2008","journal-title":"Pediatr. Transplant."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0045","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1042\/BJ20111416","article-title":"Glycogen and its metabolism: some new developments and old themes","volume":"441","author":"Roach","year":"2012","journal-title":"Biochem. J."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0050","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.bbacli.2016.02.001","article-title":"Glycogen metabolism in humans","volume":"5","author":"Adeva-Andany","year":"2016","journal-title":"BBA Clin."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0055","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1042\/bj1630193","article-title":"The influence of lysosomes on glycogen metabolism","volume":"163","author":"Geddes","year":"1977","journal-title":"Biochem. J."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0060","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1007\/s00401-008-0417-8","article-title":"Congenital type IV glycogenosis: the spectrum of pleomorphic polyglucosan bodies in muscle, nerve, and spinal cord with two novel mutations in the GBE1 gene","volume":"116","author":"Nolte","year":"2008","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0065","doi-asserted-by":"crossref","first-page":"6801","DOI":"10.1093\/hmg\/ddv385","article-title":"A novel mouse model that recapitulates adult-onset glycogenosis type 4","volume":"24","author":"Akman","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0070","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1002\/ana.410440604","article-title":"Adult polyglucosan body disease in Ashkenazi Jewish patients carrying the Tyr329Ser mutation in the glycogen-branching enzyme gene","volume":"44","author":"Lossos","year":"1998","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0075","doi-asserted-by":"crossref","first-page":"8861","DOI":"10.1073\/pnas.96.16.8861","article-title":"Systemic correction of the muscle disorder glycogen storage disease type II after hepatic targeting of a modified adenovirus vector encoding human acid-alpha-glucosidase","volume":"96","author":"Amalfitano","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0080","article-title":"A modified enzymatic method for measurement of glycogen content in glycogen storage disease type IV","author":"Yi","year":"2016","journal-title":"JIMD Rep."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0085","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ymgme.2003.08.022","article-title":"Enzyme replacement therapy in the mouse model of Pompe disease","volume":"80","author":"Raben","year":"2003","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0090","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ymthe.2004.09.017","article-title":"Replacing acid alpha-glucosidase in Pompe disease: recombinant and transgenic enzymes are equipotent, but neither completely clears glycogen from type II muscle fibers","volume":"11","author":"Raben","year":"2005","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0095","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0925-4439(97)00092-6","article-title":"Molecular cloning of acid alpha-glucosidase cDNA of Japanese quail (Coturnix coturnix japonica) and the lack of its mRNA in acid maltase deficient quails","volume":"1362","author":"Kunita","year":"1997","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0100","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1586\/eci.12.40","article-title":"Immune modulation in Pompe disease treated with enzyme replacement therapy","volume":"8","author":"Banugaria","year":"2012","journal-title":"Expert. Rev. Clin. Immunol."},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0105","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1002\/mus.22136","article-title":"Enzyme replacement therapy induces T-cell responses in late-onset Pompe disease","volume":"44","author":"Banati","year":"2011","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.ymgmr.2016.09.008_bb0110","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.ymgme.2012.01.019","article-title":"Persistence of high sustained antibodies to enzyme replacement therapy despite extensive immunomodulatory therapy in an infant with Pompe disease: need for agents to target antibody-secreting plasma cells","volume":"105","author":"Banugaria","year":"2012","journal-title":"Mol. Genet. Metab."}],"container-title":["Molecular Genetics and Metabolism Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214426916300829?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214426916300829?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T12:49:44Z","timestamp":1762001384000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214426916300829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":22,"alternative-id":["S2214426916300829"],"URL":"https:\/\/doi.org\/10.1016\/j.ymgmr.2016.09.008","relation":{},"ISSN":["2214-4269"],"issn-type":[{"value":"2214-4269","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alglucosidase alfa treatment alleviates liver disease in a mouse model of glycogen storage disease type IV","name":"articletitle","label":"Article Title"},{"value":"Molecular Genetics and Metabolism Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ymgmr.2016.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}