{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:44:25Z","timestamp":1790721865675,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T00:00:00Z","timestamp":1551916800000},"content-version":"vor","delay-in-days":371,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007393","name":"Association Fran\u00e7aise contre les Myopathies","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007393","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007391","name":"Association pour la Recherche sur le Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007391","id-type":"DOI","asserted-by":"publisher"}]},{"name":"R\u00e9gion Midi-Pyr\u00e9n\u00e9es, European funding"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.ymthe.2017.11.007","type":"journal-article","created":{"date-parts":[[2017,11,20]],"date-time":"2017-11-20T01:16:33Z","timestamp":1511140593000},"page":"902-916","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart"],"prefix":"10.1016","volume":"26","author":[{"given":"Edith","family":"Renaud-Gabardos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Tatin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fransky","family":"Hantelys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Lebas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Calise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oksana","family":"Kunduzova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Masri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Pujol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Sicard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Valet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Roncalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Chaufour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Garmy-Susini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Parini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Catherine","family":"Prats","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymthe.2017.11.007_bib1","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrcardio.2016.25","article-title":"Epidemiology and aetiology of heart failure","volume":"13","author":"Ziaeian","year":"2016","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib2","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.acvd.2010.04.006","article-title":"Update on gene therapy for myocardial ischaemia and left ventricular systolic dysfunction or heart failure","volume":"103","author":"Roncalli","year":"2010","journal-title":"Arch. Cardiovasc. Dis."},{"key":"10.1016\/j.ymthe.2017.11.007_bib3","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1161\/CIRCULATIONAHA.113.001878","article-title":"Pathological ventricular remodeling: mechanisms: part 1 of 2","volume":"128","author":"Burchfield","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.ymthe.2017.11.007_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bcp.2012.08.018","article-title":"Gene targeting in ischemic heart disease and failure: translational and clinical studies","volume":"85","author":"Eckhouse","year":"2013","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib5","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/mt.2013.13","article-title":"Mechanistic, technical, and clinical perspectives in therapeutic stimulation of coronary collateral development by angiogenic growth factors","volume":"21","author":"Rubanyi","year":"2013","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib6","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1161\/CIRCULATIONAHA.111.022889","article-title":"Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure","volume":"124","author":"Jessup","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.ymthe.2017.11.007_bib7","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1161\/CIRCRESAHA.113.302421","article-title":"Long-term effects of AAV1\/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality","volume":"114","author":"Zsebo","year":"2014","journal-title":"Circ. Res."},{"key":"10.1016\/j.ymthe.2017.11.007_bib8","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/S0140-6736(16)00082-9","article-title":"Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial","volume":"387","author":"Greenberg","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.ymthe.2017.11.007_bib9","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/gt.2015.109","article-title":"Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure","volume":"23","author":"Greenberg","year":"2016","journal-title":"Gene Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib10","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/cvr\/cvv205","article-title":"Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translation","volume":"108","author":"Rincon","year":"2015","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ymthe.2017.11.007_bib11","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1038\/mt.2015.158","article-title":"Gene therapy for heart failure: back to the bench","volume":"23","author":"Yl\u00e4-Herttuala","year":"2015","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib12","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5493\/wjem.v5.i1.11","article-title":"Internal ribosome entry site-based vectors for combined gene therapy","volume":"5","author":"Renaud-Gabardos","year":"2015","journal-title":"World J. Exp. Med."},{"key":"10.1016\/j.ymthe.2017.11.007_bib13","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1161\/01.RES.0000258873.08041.c9","article-title":"Translational induction of VEGF internal ribosome entry site elements during the early response to ischemic stress","volume":"100","author":"Bornes","year":"2007","journal-title":"Circ. Res."},{"key":"10.1016\/j.ymthe.2017.11.007_bib14","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1083\/jcb.150.1.275","article-title":"Fibroblast growth factor 2 internal ribosome entry site (IRES) activity ex\u00a0vivo and in transgenic mice reveals a stringent tissue-specific regulation","volume":"150","author":"Cr\u00e9ancier","year":"2000","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib15","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.celrep.2013.12.011","article-title":"Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1\u03b1-independent translation-mediated mechanism","volume":"6","author":"Morfoisse","year":"2014","journal-title":"Cell Rep."},{"key":"10.1016\/j.ymthe.2017.11.007_bib16","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.biochi.2006.05.019","article-title":"The use of IRES-based bicistronic vectors allows the stable expression of recombinant G-protein coupled receptors such as NPY5 and histamine 4","volume":"88","author":"Allera-Moreau","year":"2006","journal-title":"Biochimie"},{"key":"10.1016\/j.ymthe.2017.11.007_bib17","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/1472-6750-7-74","article-title":"Long term expression of bicistronic vector driven by the FGF-1 IRES in mouse muscle","volume":"7","author":"Allera-Moreau","year":"2007","journal-title":"BMC Biotechnol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib18","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1038\/gt.2008.49","article-title":"Efficient gene transfer in skeletal muscle with AAV-derived bicistronic vector using the FGF-1 IRES","volume":"15","author":"Delluc-Clavi\u00e8res","year":"2008","journal-title":"Gene Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib19","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1038\/mt.2009.211","article-title":"IRES-based vector coexpressing FGF2 and Cyr61 provides synergistic and safe therapeutics of lower limb ischemia","volume":"17","author":"Rayssac","year":"2009","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib20","first-page":"16104","article-title":"Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity","volume":"5","author":"Boal","year":"2015","journal-title":"Sci.\u00a0Rep."},{"key":"10.1016\/j.ymthe.2017.11.007_bib21","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.yjmcc.2013.07.002","article-title":"Apelin administration ameliorates high fat diet-induced cardiac hypertrophy and contractile dysfunction","volume":"63","author":"Ceylan-Isik","year":"2013","journal-title":"J.\u00a0Mol. Cell. Cardiol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib22","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1016\/j.febslet.2010.04.025","article-title":"Activation of catalase by apelin prevents oxidative stress-linked cardiac hypertrophy","volume":"584","author":"Foussal","year":"2010","journal-title":"FEBS Lett."},{"key":"10.1016\/j.ymthe.2017.11.007_bib23","doi-asserted-by":"crossref","first-page":"e71041","DOI":"10.1371\/journal.pone.0071041","article-title":"Myocardial injection of apelin-overexpressing bone marrow cells improves cardiac repair via upregulation of Sirt3 after myocardial infarction","volume":"8","author":"Li","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ymthe.2017.11.007_bib24","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1093\/eurheartj\/ehr389","article-title":"Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1","volume":"33","author":"Pchejetski","year":"2012","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ymthe.2017.11.007_bib25","doi-asserted-by":"crossref","first-page":"H585","DOI":"10.1152\/ajpheart.00821.2013","article-title":"Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3","volume":"306","author":"Zeng","year":"2014","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib26","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1038\/mt.2008.61","article-title":"Lentiviral vector-mediated SERCA2 gene transfer protects against heart failure and left ventricular remodeling after myocardial infarction in rats","volume":"16","author":"Niwano","year":"2008","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib27","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/cvr\/cvv219","article-title":"Gadd45\u03b3 regulates cardiomyocyte death and post-myocardial infarction left ventricular remodelling","volume":"108","author":"Lucas","year":"2015","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ymthe.2017.11.007_bib28","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.cardfail.2015.03.007","article-title":"The emerging potential of the Apelin-APJ system in heart failure","volume":"21","author":"Dalzell","year":"2015","journal-title":"J.\u00a0Card. Fail."},{"key":"10.1016\/j.ymthe.2017.11.007_bib29","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1161\/01.CIR.0000105723.91637.1C","article-title":"Cardiac-specific overexpression of fibroblast growth factor-2 protects against myocardial dysfunction and infarction in a murine model of low-flow ischemia","volume":"108","author":"House","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ymthe.2017.11.007_bib30","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.mvr.2013.05.005","article-title":"CXCL4L1-fibstatin cooperation inhibits tumor angiogenesis, lymphangiogenesis and metastasis","volume":"89","author":"Prats","year":"2013","journal-title":"Microvasc. Res."},{"key":"10.1016\/j.ymthe.2017.11.007_bib31","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1016\/j.bbamcr.2014.08.002","article-title":"Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis","volume":"1843","author":"Lipskaia","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ymthe.2017.11.007_bib32","doi-asserted-by":"crossref","first-page":"144","DOI":"10.2174\/156652311794940782","article-title":"Optimization of lentiviral vectors generation for biomedical and clinical research purposes: contemporary trends in technology development and applications","volume":"11","author":"Kumar","year":"2011","journal-title":"Curr. Gene Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib33","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1016\/j.jtcvs.2014.03.033","article-title":"\u201cTriplet\u201d polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors","volume":"148","author":"Mathison","year":"2014","journal-title":"J.\u00a0Thorac. Cardiovasc. Surg."},{"key":"10.1016\/j.ymthe.2017.11.007_bib34","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/gt.2015.114","article-title":"Efficacy and safety of myocardial gene transfer of adenovirus, adeno-associated virus and lentivirus vectors in the mouse heart","volume":"23","author":"Merentie","year":"2016","journal-title":"Gene Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib35","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1093\/nar\/20.6.1293","article-title":"Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy","volume":"20","author":"Morgan","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ymthe.2017.11.007_bib36","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.tibtech.2005.12.006","article-title":"E unum pluribus: multiple proteins from a self-processing polyprotein","volume":"24","author":"de Felipe","year":"2006","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib37","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1089\/hum.2013.238","article-title":"Intracerebral administration of adeno-associated viral vector serotype rh.10 carrying human SGSH and SUMF1 cDNAs in children with mucopolysaccharidosis type IIIA disease: results of a phase I\/II trial","volume":"25","author":"Tardieu","year":"2014","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.ymthe.2017.11.007_bib38","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/S0140-6736(13)61939-X","article-title":"Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson\u2019s disease: a dose escalation, open-label, phase 1\/2 trial","volume":"383","author":"Palfi","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ymthe.2017.11.007_bib39","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.ahj.2010.11.023","article-title":"Intramyocardial plasmid-encoding human vascular endothelial growth factor A165\/basic fibroblast growth factor therapy using percutaneous transcatheter approach in patients with refractory coronary artery disease (VIF-CAD)","volume":"161","author":"Kuku\u0142a","year":"2011","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ymthe.2017.11.007_bib40","doi-asserted-by":"crossref","first-page":"e3078","DOI":"10.1371\/journal.pone.0003078","article-title":"FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha","volume":"3","author":"Conte","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ymthe.2017.11.007_bib41","doi-asserted-by":"crossref","first-page":"e32","DOI":"10.1161\/CIRCRESAHA.107.158659","article-title":"Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload","volume":"101","author":"Kuba","year":"2007","journal-title":"Circ. Res."},{"key":"10.1016\/j.ymthe.2017.11.007_bib42","doi-asserted-by":"crossref","first-page":"93887","DOI":"10.1172\/jci.insight.93887","article-title":"Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction","volume":"2","author":"Tatin","year":"2017","journal-title":"JCI Insight"},{"key":"10.1016\/j.ymthe.2017.11.007_bib43","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2478\/s11658-006-0058-7","article-title":"Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression","volume":"12","author":"Atluri","year":"2007","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.ymthe.2017.11.007_bib44","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1161\/CIRCGENETICS.113.000063","article-title":"Gene network and proteomic analyses of cardiac responses to pathological and physiological stress","volume":"6","author":"Drozdov","year":"2013","journal-title":"Circ Cardiovasc Genet"},{"key":"10.1016\/j.ymthe.2017.11.007_bib45","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12920-015-0088-y","article-title":"Gene expression network analysis reveals new transcriptional regulators as novel factors in human ischemic cardiomyopathy","volume":"8","author":"Herrer","year":"2015","journal-title":"BMC Med. Genomics"},{"key":"10.1016\/j.ymthe.2017.11.007_bib46","doi-asserted-by":"crossref","first-page":"7622","DOI":"10.1128\/MCB.24.17.7622-7635.2004","article-title":"Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs","volume":"24","author":"Martineau","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ymthe.2017.11.007_bib47","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1073\/pnas.95.6.2979","article-title":"HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte","volume":"95","author":"Claycomb","year":"1998","journal-title":"Proc.\u00a0Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymthe.2017.11.007_bib48","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.ejca.2013.11.017","article-title":"Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas","volume":"50","author":"Picault","year":"2014","journal-title":"Eur. J. Cancer"}],"container-title":["Molecular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152500161730566X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152500161730566X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T17:51:43Z","timestamp":1761501103000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152500161730566X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":48,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S152500161730566X"],"URL":"https:\/\/doi.org\/10.1016\/j.ymthe.2017.11.007","relation":{},"ISSN":["1525-0016"],"issn-type":[{"value":"1525-0016","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ymthe.2017.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The American Society of Gene and Cell Therapy.","name":"copyright","label":"Copyright"}]}}