{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:18:30Z","timestamp":1787498310219,"version":"build-2736575974"},"reference-count":40,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T00:00:00Z","timestamp":1559779200000},"content-version":"vor","delay-in-days":370,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013183","name":"Key Laboratory of Malignant Tumor Gene Regulation and Target Therapy of Guangdong Higher Education Institutes, Sun Yat-sen University","doi-asserted-by":"publisher","award":["K1809001"],"award-info":[{"award-number":["K1809001"]}],"id":[{"id":"10.13039\/501100013183","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013286","name":"Specialized Research Fund for the Doctoral Program of Higher Education of China","doi-asserted-by":"publisher","award":["20110171110068"],"award-info":[{"award-number":["20110171110068"]}],"id":[{"id":"10.13039\/501100013286","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2016M590839"],"award-info":[{"award-number":["2016M590839"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["13ykpy27"],"award-info":[{"award-number":["13ykpy27"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["2012J4100078"],"award-info":[{"award-number":["2012J4100078"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012662","name":"Guangzhou Key Laboratory of Malignant Tumor Therapy and Translational Medicine","doi-asserted-by":"publisher","award":["[2013]163"],"award-info":[{"award-number":["[2013]163"]}],"id":[{"id":"10.13039\/501100012662","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81672676"],"award-info":[{"award-number":["81672676"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81272951"],"award-info":[{"award-number":["81272951"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81602379"],"award-info":[{"award-number":["81602379"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81472521"],"award-info":[{"award-number":["81472521"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2017A030311011"],"award-info":[{"award-number":["2017A030311011"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.ymthe.2018.04.002","type":"journal-article","created":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T20:31:29Z","timestamp":1522960289000},"page":"1494-1508","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["Chemotherapy-Induced Long Non-coding RNA 1 Promotes Metastasis and Chemo-Resistance of TSCC via the Wnt\/\u03b2-Catenin Signaling Pathway"],"prefix":"10.1016","volume":"26","author":[{"given":"Zhaoyu","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shule","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanyi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qunxing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weixiong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guokai","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bodu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinsong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymthe.2018.04.002_bib1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/hed.21202","article-title":"Correlation between lymphatic vessel density and regional metastasis in squamous cell carcinoma of the tongue","volume":"32","author":"Chung","year":"2010","journal-title":"Head Neck"},{"key":"10.1016\/j.ymthe.2018.04.002_bib2","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jcms.2016.10.011","article-title":"Prognosis of oral squamous cell carcinoma patients with level IV\/V metastasis: an observational study","volume":"45","author":"Hasegawa","year":"2017","journal-title":"J.\u00a0Craniomaxillofac. Surg."},{"key":"10.1016\/j.ymthe.2018.04.002_bib3","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1007\/s10555-007-9082-y","article-title":"Metastasis of squamous cell carcinoma of the oral tongue","volume":"26","author":"Sano","year":"2007","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.ymthe.2018.04.002_bib4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.canlet.2016.04.018","article-title":"Overcoming treatment resistance in cancer: current understanding and tactics","volume":"387","author":"Wu","year":"2017","journal-title":"Cancer Lett."},{"key":"10.1016\/j.ymthe.2018.04.002_bib5","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1200\/JCO.2012.43.8820","article-title":"Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma","volume":"31","author":"Zhong","year":"2013","journal-title":"J.\u00a0Clin. Oncol."},{"key":"10.1016\/j.ymthe.2018.04.002_bib6","doi-asserted-by":"crossref","first-page":"3562","DOI":"10.1200\/JCO.2005.01.057","article-title":"Randomized phase III evaluation of cisplatin plus fluorouracil versus cisplatin plus paclitaxel in advanced head and neck cancer (E1395): an intergroup trial of the Eastern Cooperative Oncology Group","volume":"23","author":"Gibson","year":"2005","journal-title":"J.\u00a0Clin. Oncol."},{"key":"10.1016\/j.ymthe.2018.04.002_bib7","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/onc.2011.263","article-title":"MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1","volume":"31","author":"Sun","year":"2012","journal-title":"Oncogene"},{"key":"10.1016\/j.ymthe.2018.04.002_bib8","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.cell.2009.11.007","article-title":"Epithelial-mesenchymal transitions in development and disease","volume":"139","author":"Thiery","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.ymthe.2018.04.002_bib9","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.cell.2016.06.028","article-title":"EMT: 2016","volume":"166","author":"Nieto","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.ymthe.2018.04.002_bib10","doi-asserted-by":"crossref","first-page":"e2201","DOI":"10.1038\/cddis.2015.324","article-title":"Galectin-1 induces hepatocellular carcinoma EMT and sorafenib resistance by activating FAK\/PI3K\/AKT signaling","volume":"7","author":"Zhang","year":"2016","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ymthe.2018.04.002_bib11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/cpr.12241","article-title":"SPOCK1 is upregulated in recurrent glioblastoma and contributes to metastasis and Temozolomide resistance","volume":"49","author":"Yu","year":"2016","journal-title":"Cell Prolif."},{"key":"10.1016\/j.ymthe.2018.04.002_bib12","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1016\/j.ymthe.2017.04.016","article-title":"lncRNA HOXD-AS1 regulates proliferation and chemo-resistance of castration-resistant prostate cancer via recruiting WDR5","volume":"25","author":"Gu","year":"2017","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2018.04.002_bib13","doi-asserted-by":"crossref","first-page":"5648","DOI":"10.1038\/onc.2015.18","article-title":"SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer","volume":"34","author":"Xu","year":"2015","journal-title":"Oncogene"},{"key":"10.1016\/j.ymthe.2018.04.002_bib14","doi-asserted-by":"crossref","first-page":"5350","DOI":"10.1038\/onc.2016.75","article-title":"NF-\u03baB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer","volume":"35","author":"\u00d6ze\u015f","year":"2016","journal-title":"Oncogene"},{"key":"10.1016\/j.ymthe.2018.04.002_bib15","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.canlet.2016.07.015","article-title":"Long non-coding RNA LINC01133 inhibits epithelial-mesenchymal transition and metastasis in colorectal cancer by interacting with SRSF6","volume":"380","author":"Kong","year":"2016","journal-title":"Cancer Lett."},{"key":"10.1016\/j.ymthe.2018.04.002_bib16","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.ccell.2015.02.004","article-title":"A cytoplasmic NF-\u03baB interacting long noncoding RNA blocks I\u03baB phosphorylation and suppresses breast cancer metastasis","volume":"27","author":"Liu","year":"2015","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ymthe.2018.04.002_bib17","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1111\/cas.12499","article-title":"miR-639 regulates transforming growth factor beta-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting FOXC1","volume":"105","author":"Lin","year":"2014","journal-title":"Cancer Sci."},{"key":"10.1016\/j.ymthe.2018.04.002_bib18","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/bjc.2013.770","article-title":"Akt\/Ezrin Tyr353\/NF-\u03baB pathway regulates EGF-induced EMT and metastasis in tongue squamous cell carcinoma","volume":"110","author":"Wang","year":"2014","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.ymthe.2018.04.002_bib19","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.canlet.2016.03.024","article-title":"Epigenetic silencing of miR-490-3p promotes development of an aggressive colorectal cancer phenotype through activation of the Wnt\/\u03b2-catenin signaling pathway","volume":"376","author":"Zheng","year":"2016","journal-title":"Cancer Lett."},{"key":"10.1016\/j.ymthe.2018.04.002_bib20","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.cellsig.2006.11.001","article-title":"Multiplicity of the interactions of Wnt proteins and their receptors","volume":"19","author":"Kikuchi","year":"2007","journal-title":"Cell. Signal."},{"key":"10.1016\/j.ymthe.2018.04.002_bib21","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/labinvest.2015.144","article-title":"The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies","volume":"96","author":"Yang","year":"2016","journal-title":"Lab. Invest."},{"key":"10.1016\/j.ymthe.2018.04.002_bib22","doi-asserted-by":"crossref","first-page":"e226","DOI":"10.1038\/oncsis.2016.32","article-title":"Migration and invasion is inhibited by silencing ROR1 and ROR2 in chemoresistant ovarian cancer","volume":"5","author":"Henry","year":"2016","journal-title":"Oncogenesis"},{"key":"10.1016\/j.ymthe.2018.04.002_bib23","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12943-017-0583-1","article-title":"The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt\/\u03b2-catenin signaling","volume":"16","author":"Han","year":"2017","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.ymthe.2018.04.002_bib24","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1007\/s13277-015-3998-6","article-title":"Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt\/\u03b2-catenin pathway in human ovarian cancer","volume":"37","author":"Li","year":"2016","journal-title":"Tumour Biol."},{"key":"10.1016\/j.ymthe.2018.04.002_bib25","first-page":"2385","article-title":"Overexpression of long non-coding RNA HOTTIP increases chemoresistance of osteosarcoma cell by activating the Wnt\/\u03b2-catenin pathway","volume":"8","author":"Li","year":"2016","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.ymthe.2018.04.002_bib26","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.stem.2015.03.003","article-title":"The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling","volume":"16","author":"Wang","year":"2015","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.ymthe.2018.04.002_bib27","doi-asserted-by":"crossref","first-page":"16654","DOI":"10.1073\/pnas.1205822109","article-title":"Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression","volume":"109","author":"Wu","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymthe.2018.04.002_bib28","doi-asserted-by":"crossref","first-page":"3364","DOI":"10.1158\/0008-5472.CAN-15-2302","article-title":"c-Myb enhances breast cancer invasion and metastasis through the Wnt\/\u03b2-catenin\/Axin2 pathway","volume":"76","author":"Li","year":"2016","journal-title":"Cancer Res."},{"key":"10.1016\/j.ymthe.2018.04.002_bib29","first-page":"3503","article-title":"Upregulation of lncRNA HNF1A-AS1 promotes cell proliferation and metastasis in osteosarcoma through activation of the Wnt\/\u03b2-catenin signaling pathway","volume":"8","author":"Zhao","year":"2016","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.ymthe.2018.04.002_bib30","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1038\/onc.2016.339","article-title":"FERMT1 mediates epithelial-mesenchymal transition to promote colon cancer metastasis via modulation of \u03b2-catenin transcriptional activity","volume":"36","author":"Liu","year":"2017","journal-title":"Oncogene"},{"key":"10.1016\/j.ymthe.2018.04.002_bib31","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.canlet.2013.05.005","article-title":"Inhibition of cytoplasmic GSK-3\u03b2 increases cisplatin resistance through activation of Wnt\/\u03b2-catenin signaling in A549\/DDP cells","volume":"336","author":"Gao","year":"2013","journal-title":"Cancer Lett."},{"key":"10.1016\/j.ymthe.2018.04.002_bib32","doi-asserted-by":"crossref","first-page":"11652","DOI":"10.18632\/oncotarget.3457","article-title":"LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer","volume":"6","author":"Shi","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.ymthe.2018.04.002_bib33","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1186\/1471-2407-14-932","article-title":"LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition","volume":"14","author":"Han","year":"2014","journal-title":"BMC Cancer"},{"key":"10.1016\/j.ymthe.2018.04.002_bib34","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.gendis.2015.12.004","article-title":"Wnt\/\u03b2-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance","volume":"3","author":"Mohammed","year":"2016","journal-title":"Genes Dis."},{"key":"10.1016\/j.ymthe.2018.04.002_bib35","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1097\/IGC.0b013e31820aaadb","article-title":"Wnt5a as a predictor in poor clinical outcome of patients and a mediator in chemoresistance of ovarian cancer","volume":"21","author":"Peng","year":"2011","journal-title":"Int. J. Gynecol. Cancer"},{"key":"10.1016\/j.ymthe.2018.04.002_bib36","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1172\/JCI70156","article-title":"WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors","volume":"124","author":"Anastas","year":"2014","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.ymthe.2018.04.002_bib37","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jhep.2012.10.033","article-title":"Are Hedgehog and Wnt\/\u03b2-catenin pathways involved in hepatitis C virus-mediated EMT?","volume":"58","author":"Conti","year":"2013","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.ymthe.2018.04.002_bib38","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s12943-017-0700-1","article-title":"FOXP3 promotes tumor growth and metastasis by activating Wnt\/\u03b2-catenin signaling pathway and EMT in non-small cell lung cancer","volume":"16","author":"Yang","year":"2017","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.ymthe.2018.04.002_bib39","doi-asserted-by":"crossref","first-page":"81727","DOI":"10.18632\/oncotarget.13172","article-title":"KY1022, a small molecule destabilizing Ras via targeting the Wnt\/\u03b2-catenin pathway, inhibits development of metastatic colorectal cancer","volume":"7","author":"Cho","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.ymthe.2018.04.002_bib40","doi-asserted-by":"crossref","first-page":"38010","DOI":"10.18632\/oncotarget.9380","article-title":"CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical\u00a0Wnt signaling","volume":"7","author":"Tseng","year":"2016","journal-title":"Oncotarget"}],"container-title":["Molecular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152500161830159X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152500161830159X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T17:52:23Z","timestamp":1761501143000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152500161830159X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S152500161830159X"],"URL":"https:\/\/doi.org\/10.1016\/j.ymthe.2018.04.002","relation":{},"ISSN":["1525-0016"],"issn-type":[{"value":"1525-0016","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chemotherapy-Induced Long Non-coding RNA 1 Promotes Metastasis and Chemo-Resistance of TSCC via the Wnt\/\u03b2-Catenin Signaling Pathway","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ymthe.2018.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The American Society of Gene and Cell Therapy.","name":"copyright","label":"Copyright"}]}}