{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:23:41Z","timestamp":1778617421624,"version":"3.51.4"},"reference-count":62,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T00:00:00Z","timestamp":1642118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP 20K17150"],"award-info":[{"award-number":["JP 20K17150"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.ymthe.2022.01.008","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T11:43:04Z","timestamp":1641555784000},"page":"1239-1251","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Engineered clustered myoblast cell injection augments angiogenesis and muscle regeneration in peripheral artery disease"],"prefix":"10.1016","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0868-4422","authenticated-orcid":false,"given":"Keisuke","family":"Miyake","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Miyagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akima","family":"Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Sawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymthe.2022.01.008_bib1","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(13)61249-0","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis","volume":"382","author":"Fowkes","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.ymthe.2022.01.008_bib2","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1016\/j.jvs.2019.02.016","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischemia","volume":"69","author":"Conte","year":"2019","journal-title":"J.\u00a0Vasc. Surg."},{"issue":"Suppl S","key":"10.1016\/j.ymthe.2022.01.008_bib3","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.jvs.2006.12.037","article-title":"Inter-society consensus for the management of peripheral arterial disease (TASC II)","volume":"45","author":"Norgren","year":"2007","journal-title":"J.\u00a0Vasc. Surg."},{"key":"10.1016\/j.ymthe.2022.01.008_bib4","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1016\/S0140-6736(02)08937-7","article-title":"Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial","volume":"359","author":"Lederman","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.ymthe.2022.01.008_bib5","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.ahj.2008.06.025","article-title":"Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells (Therapeutic Angiogenesis by Cell Transplantation [TACT] trial) in patients with chronic limb ischemia","volume":"156","author":"Matoba","year":"2008","journal-title":"Am. Heart J."},{"key":"10.1016\/j.ymthe.2022.01.008_bib6","first-page":"2155","article-title":"Autologous transplantation of granulocyte colony \u2013 stimulating factor \u2013 cells improves critical limb ischemia in","volume":"28","author":"Huang","year":"2005","journal-title":"Emerg. Treat. Technol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib7","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1161\/CIRCULATIONAHA.114.012913","article-title":"Effect of repetitive intra-arterial infusion of bone marrow mononuclear cells in patients with no-option limb ischemia: the randomized, double-blind, placebo-controlled Rejuvenating Endothelial Progenitor Cells via Transcutaneous Intra-arterial Supplement","volume":"131","author":"Teraa","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.ymthe.2022.01.008_bib8","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1161\/CIRCINTERVENTIONS.112.968321","article-title":"A randomized, controlled pilot study of autologous CD34+ cell therapy for critical limb ischemia","volume":"5","author":"Losordo","year":"2012","journal-title":"Circ. Cardiovasc. Interv."},{"key":"10.1016\/j.ymthe.2022.01.008_bib9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/stem.2751","article-title":"Concise review: cell therapy for critical limb ischemia: an integrated review of preclinical and clinical studies","volume":"36","author":"Qadura","year":"2018","journal-title":"Stem Cells"},{"key":"10.1016\/j.ymthe.2022.01.008_bib10","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ejvs.2017.07.018","article-title":"Editor\u2019s choice \u2013 2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European society for vascular surgery (ESVS)","volume":"55","author":"Aboyans","year":"2018","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"10.1016\/j.ymthe.2022.01.008_bib11","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jacbts.2016.01.009","article-title":"Extracellular matrix hydrogel promotes tissue remodeling, arteriogenesis, and perfusion in a rat hindlimb ischemia model","volume":"1","author":"Ungerleider","year":"2016","journal-title":"JACC Basic Transl. Sci."},{"issue":"6S","key":"10.1016\/j.ymthe.2022.01.008_bib12","doi-asserted-by":"crossref","first-page":"137S","DOI":"10.1016\/j.jvs.2018.08.169","article-title":"Survival prediction in patients with chronic limb-threatening ischemia who undergo infrainguinal revascularization","volume":"69","author":"Simons","year":"2019","journal-title":"J.\u00a0Vasc. Surg."},{"key":"10.1016\/j.ymthe.2022.01.008_bib13","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.avsg.2020.07.033","article-title":"Predictive model for postoperative ambulatory function after lower extremity bypass in chronic limb-threatening ischemia","volume":"71","author":"Miyake","year":"2020","journal-title":"Ann. Vasc. Surg."},{"key":"10.1016\/j.ymthe.2022.01.008_bib14","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/TP.0b013e3181e6f201","article-title":"Impaired myocardium regeneration with skeletal cell sheets-A preclinical trial for tissue-engineered regeneration therapy","volume":"90","author":"Miyagawa","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.ymthe.2022.01.008_bib15","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/(SICI)1097-4636(19990615)45:4<355::AID-JBM10>3.0.CO;2-7","article-title":"Decrease in culture temperature releases monolayer endothelial cell sheets together with deposited fibronectin matrix from temperature-responsive culture surfaces","volume":"45","author":"Kushida","year":"1999","journal-title":"J.\u00a0Biomed. Mater. Res."},{"key":"10.1016\/j.ymthe.2022.01.008_bib16","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1097\/01.tp.0000181163.69108.dd","article-title":"Tissue cardiomyoplasty using bioengineered contractile cardiomyocyte sheets to repair damaged myocardium: their integration with recipient myocardium","volume":"80","author":"Miyagawa","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.ymthe.2022.01.008_bib17","first-page":"457","article-title":"Laminin \u03b12-secreting fibroblasts enhance the therapeutic effect of skeletal myoblast sheets","volume":"51","author":"Uchinaka","year":"2017","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.ymthe.2022.01.008_bib18","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1172\/JCI25964","article-title":"Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes","volume":"116","author":"Uemura","year":"2006","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.ymthe.2022.01.008_bib19","doi-asserted-by":"crossref","first-page":"015020","DOI":"10.1088\/1758-5090\/8\/1\/015020","article-title":"Design, fabrication and perivascular implantation of bioactive scaffolds engineered with human adventitial progenitor cells for stimulation of arteriogenesis in peripheral ischemia","volume":"8","author":"Carrabba","year":"2016","journal-title":"Biofabrication"},{"key":"10.1016\/j.ymthe.2022.01.008_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2044-5040-1-21","article-title":"Aberrant repair and fibrosis development in skeletal muscle","volume":"1","author":"Mann","year":"2011","journal-title":"Skeletal Muscle"},{"key":"10.1016\/j.ymthe.2022.01.008_bib21","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.cell.2005.05.010","article-title":"Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche","volume":"122","author":"Collins","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.ymthe.2022.01.008_bib22","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1152\/physrev.00043.2011","article-title":"Satellite cells and the muscle stem cell niche","volume":"93","author":"Yin","year":"2013","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ymthe.2022.01.008_bib23","doi-asserted-by":"crossref","first-page":"6167","DOI":"10.1093\/nar\/17.15.6167","article-title":"Expression and DNA sequence analysis of a human embryonic skeletal muscle mvosin heavy chain gene","volume":"17","author":"Karsch-Mizrachi","year":"1989","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ymthe.2022.01.008_bib24","doi-asserted-by":"crossref","first-page":"9551","DOI":"10.1038\/s41598-019-45923-4","article-title":"Critical limb ischemia induces remodeling of skeletal muscle motor unit, myonuclear-, and mitochondrial-domains","volume":"9","author":"Mohiuddin","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ymthe.2022.01.008_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13287-015-0063-8","article-title":"Myoblast-conditioned media improve regeneration and revascularization of ischemic muscles in diabetic mice","volume":"6","author":"Kozakowska","year":"2015","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.ymthe.2022.01.008_bib26","doi-asserted-by":"crossref","first-page":"eaay6391","DOI":"10.1126\/sciadv.aay6391","article-title":"Macrophages of diverse phenotypes drive vascularization of engineered tissues","volume":"6","author":"Graney","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.ymthe.2022.01.008_bib27","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jnutbio.2018.08.004","article-title":"M1 macrophage subtypes activation and adipocyte dysfunction worsen during prolonged consumption of a fructose-rich diet","volume":"61","author":"Gambaro","year":"2018","journal-title":"J.\u00a0Nutr. Biochem."},{"key":"10.1016\/j.ymthe.2022.01.008_bib28","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/nature00821","article-title":"VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism","volume":"417","author":"Gerber","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.ymthe.2022.01.008_bib29","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/nm0603-653","article-title":"Angiogenesis in health and disease","volume":"9","author":"Carmeliet","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.ymthe.2022.01.008_bib30","first-page":"548","article-title":"Neuronal replacement from endogenous precursors in the adult","volume":"9","author":"Arvidsson","year":"2003","journal-title":"Nat. Med."},{"key":"10.1016\/j.ymthe.2022.01.008_bib31","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1161\/01.CIR.97.4.381","article-title":"Potentiated angiogenic effect of scatter factor\/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis","volume":"97","author":"Van Belle","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.ymthe.2022.01.008_bib32","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/72212","article-title":"Leaky vessels? Call Ang1!","volume":"6","author":"Jain","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.ymthe.2022.01.008_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12964-020-00595-w","article-title":"ERK and Akt exhibit distinct signaling responses following stimulation by pro-angiogenic factors","volume":"18","author":"Song","year":"2020","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.ymthe.2022.01.008_bib34","doi-asserted-by":"crossref","first-page":"23646","DOI":"10.1074\/jbc.M115.686519","article-title":"Lipin1 regulates skeletal muscle differentiation through extracellular signal-regulated kinase (ERK) activation and cyclin D complex-regulated cell cycle withdrawal","volume":"290","author":"Jiang","year":"2015","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.ymthe.2022.01.008_bib35","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1439-0264.1995.tb00016.x","article-title":"Capillary supply during development of individual regenerating muscle fibers","volume":"24","author":"Luque","year":"1995","journal-title":"Anat. Histol. Embryol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib36","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1091\/mbc.e06-08-0693","article-title":"Muscle satellite cells and endothelial cells: close neighbors and privileged partners","volume":"18","author":"Christov","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ymthe.2022.01.008_bib37","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.ymthe.2004.08.007","article-title":"Vascular endothelial growth factor stimulates skeletal muscle regeneration in\u00a0Vivo","volume":"10","author":"Arsic","year":"2004","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2022.01.008_bib38","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/dbio.2001.0416","article-title":"Syndecan-3 and syndecan-4 specifically mark skeletal muscle satellite cells and are implicated in satellite cell maintenance and muscle regeneration","volume":"239","author":"Cornelison","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib39","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/jcp.1041650211","article-title":"Hepatocyte growth factor activates quiescent skeletal muscle satellite cells in\u00a0vitro","volume":"165","author":"Allen","year":"1995","journal-title":"J.\u00a0Cell Physiol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib40","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.stem.2018.09.007","article-title":"Muscle satellite cell cross-talk with a vascular niche maintains quiescence via VEGF and notch signaling","volume":"23","author":"Verma","year":"2018","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.ymthe.2022.01.008_bib41","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/nature11438","article-title":"The aged niche disrupts muscle stem cell quiescence","volume":"490","author":"Chakkalakal","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.ymthe.2022.01.008_bib42","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s00441-018-2955-2","article-title":"Skeletal muscle fibrosis: an overview","volume":"375","author":"Mahdy","year":"2019","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.ymthe.2022.01.008_bib43","first-page":"341","article-title":"Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states","volume":"14","author":"Morris","year":"2011","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.ymthe.2022.01.008_bib44","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.2337\/db09-0287","article-title":"Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity","volume":"59","author":"Wentworth","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.ymthe.2022.01.008_bib45","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.2337\/db09-1402","article-title":"Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet - induced obesity in mice","volume":"59","author":"Shaul","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.ymthe.2022.01.008_bib46","doi-asserted-by":"crossref","first-page":"6425","DOI":"10.1002\/jcp.26429","article-title":"Macrophage plasticity, polarization, and function in health and disease","volume":"233","author":"Shapouri-Moghaddam","year":"2018","journal-title":"J.\u00a0Cell Physiol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib47","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1084\/jem.20070075","article-title":"Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis","volume":"204","author":"Arnold","year":"2007","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.ymthe.2022.01.008_bib48","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.cmet.2020.05.004","article-title":"Endothelial lactate controls muscle regeneration from ischemia by inducing M2-like macrophage polarization","volume":"31","author":"Zhang","year":"2020","journal-title":"Cell Metab."},{"key":"10.1016\/j.ymthe.2022.01.008_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13287-018-0821-5","article-title":"Mesenchymal stem cells and extracellular matrix scaffold promote muscle regeneration by synergistically regulating macrophage polarization toward the M2 phenotype","volume":"9","author":"Qiu","year":"2018","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.ymthe.2022.01.008_bib50","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/jbm.a.35894","article-title":"Solubilized extracellular matrix bioscaffolds derived from diverse source tissues differentially influence macrophage phenotype","volume":"105","author":"Dziki","year":"2017","journal-title":"J.\u00a0Biomed. Mater. Res. A"},{"key":"10.1016\/j.ymthe.2022.01.008_bib51","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.1038\/s41467-019-12545-3","article-title":"In\u00a0vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration","volume":"10","author":"Zhu","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ymthe.2022.01.008_bib52","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1039\/C4BM00189C","article-title":"Fractionation of an ECM hydrogel into structural and soluble components reveals distinctive roles in regulating macrophage behavior","volume":"2","author":"Slivka","year":"2014","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.ymthe.2022.01.008_bib53","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41467-017-00522-7","article-title":"Macrophage-released ADAMTS1 promotes muscle stem cell activation","volume":"8","author":"Du","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ymthe.2022.01.008_bib54","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1161\/ATVBAHA.116.307743","article-title":"AMP-Activated protein kinase \u03b11 in macrophages promotes collateral remodeling and arteriogenesis in mice in\u00a0vivo","volume":"36","author":"Zhu","year":"2016","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib55","doi-asserted-by":"crossref","first-page":"C383","DOI":"10.1152\/ajpcell.00322.2001","article-title":"ECM is required for skeletal muscle differentiation independently of muscle regulatory factor expression","volume":"282","author":"Osses","year":"2002","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib56","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1002\/cbin.10725","article-title":"The role of TGF-\u03b21 during skeletal muscle regeneration","volume":"41","author":"Delaney","year":"2017","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.ymthe.2022.01.008_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13287-020-01682-y","article-title":"A novel role of vitronectin in promoting survival of mesenchymal stem cells under serum deprivation stress","volume":"11","author":"Goyal","year":"2020","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.ymthe.2022.01.008_bib58","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1073\/pnas.87.9.3264","article-title":"Merosin, a tissue-specific basement membrane protein, is a laminin-like protein","volume":"87","author":"Ehrig","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.ymthe.2022.01.008_bib59","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S1357-2725(99)00005-9","article-title":"Vitronectin","volume":"31","author":"Schvartz","year":"1999","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib60","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.semcdb.2018.08.007","article-title":"Extracellular matrix scaffolding in angiogenesis and capillary homeostasis","volume":"89","author":"Marchand","year":"2019","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ymthe.2022.01.008_bib61","doi-asserted-by":"crossref","first-page":"4451","DOI":"10.1242\/dev.071381","article-title":"Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis","volume":"138","author":"Stenzel","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.ymthe.2022.01.008_bib62","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.jtcvs.2009.02.004","article-title":"Layered implantation of myoblast sheets attenuates adverse cardiac remodeling of the infarcted heart","volume":"138","author":"Sekiya","year":"2009","journal-title":"J.\u00a0Thorac. Cardiovasc. Surg."}],"container-title":["Molecular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001622000089?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001622000089?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:06:06Z","timestamp":1778616366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525001622000089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":62,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["S1525001622000089"],"URL":"https:\/\/doi.org\/10.1016\/j.ymthe.2022.01.008","relation":{},"ISSN":["1525-0016"],"issn-type":[{"value":"1525-0016","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Engineered clustered myoblast cell injection augments angiogenesis and muscle regeneration in peripheral artery disease","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ymthe.2022.01.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors.","name":"copyright","label":"Copyright"}]}}