{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T05:32:27Z","timestamp":1775107947875,"version":"3.50.1"},"reference-count":74,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.ymthe.2025.02.038","type":"journal-article","created":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T02:51:09Z","timestamp":1740711069000},"page":"1701-1719","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["A VSV-based oral rabies vaccine was sentineled by Peyer\u2019s patches and induced a timely and durable immune response"],"prefix":"10.1016","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1978-5808","authenticated-orcid":false,"given":"Shen","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenshan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiqi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongkun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianzhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiecheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianzhu","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feihu","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymthe.2025.02.038_bib1","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/S0140-6736(13)62707-5","article-title":"Current status of rabies and prospects for elimination","volume":"384","author":"Fooks","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ymthe.2025.02.038_bib2","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2017.91","article-title":"Rabies","volume":"3","author":"Fooks","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.ymthe.2025.02.038_bib3","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.g7827","article-title":"The prevention and management of rabies","volume":"350","author":"Crowcroft","year":"2015","journal-title":"Bmj"},{"key":"10.1016\/j.ymthe.2025.02.038_bib4","article-title":"Estimating the global burden of endemic canine rabies","volume":"9","author":"Hampson","year":"2015","journal-title":"Plos Negl. Trop. Dis."},{"key":"10.1016\/j.ymthe.2025.02.038_bib5","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2012.0143","article-title":"Progress towards eliminating canine rabies: policies and perspectives from Latin America and the Caribbean","volume":"368","author":"Vigilato","year":"2013","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.ymthe.2025.02.038_bib6","doi-asserted-by":"crossref","first-page":"20837","DOI":"10.1073\/pnas.1308817110","article-title":"Resolving the roles of immunity, pathogenesis, and immigration for rabies persistence in vampire bats","volume":"110","author":"Blackwood","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymthe.2025.02.038_bib7","doi-asserted-by":"crossref","first-page":"519","DOI":"10.20506\/rst.37.2.2820","article-title":"Animal rabies in the People's Republic of China","volume":"37","author":"Tu","year":"2018","journal-title":"Rev. Sci. Tech."},{"key":"10.1016\/j.ymthe.2025.02.038_bib8","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1111\/tbed.13415","article-title":"Rabies surveillance in wild mammals in South of Brazil","volume":"67","author":"Campos","year":"2020","journal-title":"Transbound. Emerg. Dis."},{"key":"10.1016\/j.ymthe.2025.02.038_bib9","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3389\/fpubh.2020.00318","article-title":"Using Surveillance of Animal Bite Patients to Decipher Potential Risks of Rabies Exposure From Domestic Animals and Wildlife in Brazil","volume":"8","author":"Benavides","year":"2020","journal-title":"Front. Public Health"},{"key":"10.1016\/j.ymthe.2025.02.038_bib10","doi-asserted-by":"crossref","first-page":"e828","DOI":"10.1016\/S2214-109X(18)30302-4","article-title":"New global strategic plan to eliminate dog-mediated rabies by 2030","volume":"6","author":"Minghui","year":"2018","journal-title":"Lancet Glob. Health"},{"key":"10.1016\/j.ymthe.2025.02.038_bib11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/322373a0","article-title":"Oral vaccination of the fox against rabies using a live recombinant vaccinia virus","volume":"322","author":"Blancou","year":"1986","journal-title":"Nature"},{"key":"10.1016\/j.ymthe.2025.02.038_bib12","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.antiviral.2013.07.012","article-title":"Genetic strain modification of a live rabies virus vaccine widely used in Europe for wildlife oral vaccination","volume":"100","author":"Cliquet","year":"2013","journal-title":"Antivir. Res."},{"key":"10.1016\/j.ymthe.2025.02.038_bib13","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.ymthe.2006.03.027","article-title":"A chimpanzee-origin adenovirus vector expressing the rabies virus glycoprotein as an oral vaccine against inhalation infection with rabies virus","volume":"14","author":"Zhou","year":"2006","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2025.02.038_bib14","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0264-410X(94)90095-7","article-title":"Vaccination against rabies: construction and characterization of SAG2, a double avirulent derivative of SADBern","volume":"12","author":"Lafay","year":"1994","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.antiviral.2015.06.011","article-title":"Genetically modified rabies virus ERA strain is safe and induces long-lasting protective immune response in dogs after oral vaccination","volume":"121","author":"Shuai","year":"2015","journal-title":"Antivir. Res."},{"key":"10.1016\/j.ymthe.2025.02.038_bib16","unstructured":"WHO Expert Consultation on Rabies. Second report. (2013). World Health Organ Tech Rep Ser, 1-139, back cover."},{"key":"10.1016\/j.ymthe.2025.02.038_bib17","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.1016\/S0264-410X(01)00186-4","article-title":"Rapid clearance of SAG-2 rabies virus from dogs after oral vaccination","volume":"19","author":"Orciari","year":"2001","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib18","doi-asserted-by":"crossref","first-page":"3409","DOI":"10.1016\/j.vaccine.2006.12.054","article-title":"The safety and efficacy of the oral rabies vaccine SAG2 in Indian stray dogs","volume":"25","author":"Cliquet","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib19","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/0264-410X(95)00244-U","article-title":"Immunogenicity, efficacy and safety of an oral rabies vaccine (SAG-2) in dogs","volume":"14","author":"Fekadu","year":"1996","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib20","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/0264-410X(94)90093-0","article-title":"Assay of oral vaccination of dogs against rabies in Tunisia with the vaccinal strain SADBern","volume":"12","author":"Haddad","year":"1994","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib21","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1863-2378.2008.01215.x","article-title":"Immunogenicity and safety of recombinant rabies viruses used for oral vaccination of stray dogs and wildlife","volume":"56","author":"Faber","year":"2009","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.ymthe.2025.02.038_bib22","doi-asserted-by":"crossref","first-page":"4743","DOI":"10.1016\/j.vaccine.2017.09.096","article-title":"Evaluation of immune responses in dogs to oral rabies vaccine under field conditions","volume":"37","author":"Smith","year":"2019","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib23","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1007\/s00705-017-3499-6","article-title":"Protective immune response of oral rabies vaccine in stray dogs, corsacs and steppe wolves after a single immunization","volume":"162","author":"Zhugunissov","year":"2017","journal-title":"Arch. Virol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib24","first-page":"1204","article-title":"Human vaccinia infection after contact with a raccoon rabies vaccine bait - Pennsylvania, 2009","volume":"58","year":"2009","journal-title":"MMWR. Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.ymthe.2025.02.038_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0005547","article-title":"Mucosal immunization of cynomolgus macaques with the VSVDeltaG\/ZEBOVGP vaccine stimulates strong ebola GP-specific immune responses","volume":"4","author":"Qiu","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.ymthe.2025.02.038_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.antiviral.2023.105765","article-title":"Oral delivery of a chitosan adjuvanted COVID-19 vaccine provides long-lasting and broad-spectrum protection against SARS-CoV-2 variants of concern in golden hamsters","volume":"220","author":"Wang","year":"2023","journal-title":"Antivir. Res."},{"key":"10.1016\/j.ymthe.2025.02.038_bib27","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.virs.2022.02.008","article-title":"A single dose of recombinant VSV-RABV(G) vaccine provides full protection against RABV challenge","volume":"37","author":"Liang","year":"2022","journal-title":"Virol. Sin."},{"key":"10.1016\/j.ymthe.2025.02.038_bib28","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/s41392-023-01408-5","article-title":"Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases","volume":"8","author":"Wang","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.ymthe.2025.02.038_bib29","doi-asserted-by":"crossref","first-page":"702","DOI":"10.3201\/eid2104.142012","article-title":"Safety of recombinant VSV-Ebola virus vaccine vector in pigs","volume":"21","author":"de Wit","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ymthe.2025.02.038_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001567","article-title":"Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates","volume":"6","author":"Mire","year":"2012","journal-title":"Plos Negl. Trop. Dis."},{"key":"10.1016\/j.ymthe.2025.02.038_bib31","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/ni.2352","article-title":"The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells","volume":"13","author":"Kanaya","year":"2012","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib32","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1128\/jvi.68.2.713-719.1994","article-title":"Rescue of synthetic genomic RNA analogs of rabies virus by plasmid-encoded proteins","volume":"68","author":"Conzelmann","year":"1994","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib33","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.7589\/2013-02-035","article-title":"Oral vaccination of captive small Indian mongoose (Herpestes auropunctatus) against rabies","volume":"49","author":"Vos","year":"2013","journal-title":"J.\u00a0Wildl. Dis."},{"key":"10.1016\/j.ymthe.2025.02.038_bib34","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s13567-014-0077-8","article-title":"Twenty year experience of the oral rabies vaccine SAG2 in wildlife: a global review","volume":"45","author":"M\u00e4hl","year":"2014","journal-title":"Vet. Res."},{"key":"10.1016\/j.ymthe.2025.02.038_bib35","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1016\/j.vaccine.2008.04.007","article-title":"Genetic characterisation of attenuated SAD rabies virus strains used for oral vaccination of wildlife","volume":"26","author":"Geue","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib36","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13567-017-0459-9","article-title":"Oral vaccination of wildlife using a vaccinia-rabies-glycoprotein recombinant virus vaccine (RABORAL V-RG(\u00ae)): a global review","volume":"48","author":"Maki","year":"2017","journal-title":"Vet. Res."},{"key":"10.1016\/j.ymthe.2025.02.038_bib37","first-page":"1","article-title":"WHO Expert Committee on Rabies: eighth report","volume":"523","year":"1991","journal-title":"World Health Organ Tech. Rep. Ser."},{"key":"10.1016\/j.ymthe.2025.02.038_bib38","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.ymthe.2024.12.041","article-title":"A nucleoside-modified rabies mRNA vaccine induces long-lasting and comprehensive immune responses in mice and non-human primates","volume":"33","author":"Wang","year":"2025","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ymthe.2025.02.038_bib39","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1186\/s12985-022-01919-7","article-title":"An mRNA-based rabies vaccine induces strong protective immune responses in mice and dogs","volume":"19","author":"Li","year":"2022","journal-title":"Virol. J."},{"key":"10.1016\/j.ymthe.2025.02.038_bib40","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1038\/s41541-024-00925-w","article-title":"Safety and efficacy assessment of an mRNA rabies vaccine in dogs, rodents, and cynomolgus macaques","volume":"9","author":"Li","year":"2024","journal-title":"NPJ Vaccin."},{"key":"10.1016\/j.ymthe.2025.02.038_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/vbz.2008.0046","article-title":"Rabies in China: an update","volume":"9","author":"Hu","year":"2009","journal-title":"Vector Borne Zoonotic Dis."},{"key":"10.1016\/j.ymthe.2025.02.038_bib42","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1136\/vr.h4196","article-title":"Rabies: 100 per cent fatal, 100 per cent preventable","volume":"177","author":"Abela-Ridder","year":"2015","journal-title":"Vet. Rec."},{"key":"10.1016\/j.ymthe.2025.02.038_bib43","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.1038\/s41467-023-39421-5","article-title":"Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses","volume":"14","author":"Hellgren","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ymthe.2025.02.038_bib44","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/s41541-017-0032-6","article-title":"Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines","volume":"2","author":"Lutz","year":"2017","journal-title":"NPJ Vaccin."},{"key":"10.1016\/j.ymthe.2025.02.038_bib45","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/S0140-6736(17)31665-3","article-title":"Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial","volume":"390","author":"Alberer","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.ymthe.2025.02.038_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004746","article-title":"An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs","volume":"10","author":"Schnee","year":"2016","journal-title":"Plos Negl. Trop. Dis."},{"key":"10.1016\/j.ymthe.2025.02.038_bib47","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1080\/22221751.2021.1923341","article-title":"A novel oral rabies vaccine enhances the immunogenicity through increasing dendritic cells activation and germinal center formation by expressing U-OMP19 in a mouse model","volume":"10","author":"Zhao","year":"2021","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.ymthe.2025.02.038_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.128085","article-title":"Development of a novel multi-epitope oral DNA vaccine for rabies based on a food-borne microbial vector","volume":"255","author":"Ding","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib49","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.1080\/21645515.2019.1649532","article-title":"Recombinant vesicular stomatitis virus vector vaccines for whom blueprint priority pathogens","volume":"15","author":"Fathi","year":"2019","journal-title":"Hum. Vaccin. Immunother."},{"key":"10.1016\/j.ymthe.2025.02.038_bib50","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1053\/tvjl.1998.0303","article-title":"Vesicular stomatitis","volume":"157","author":"Letchworth","year":"1999","journal-title":"Vet. J."},{"key":"10.1016\/j.ymthe.2025.02.038_bib51","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1099\/jgv.0.001329","article-title":"Comparative evaluation of pathogenicity of three isolates of vesicular stomatitis virus (Indiana serotype) in pigs","volume":"100","author":"Morozov","year":"2019","journal-title":"J.\u00a0Gen. Virol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib52","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.cvfa.2024.01.005","article-title":"Vesicular Stomatitis Virus","volume":"40","author":"Pelzel-McCluskey","year":"2024","journal-title":"Vet. Clin. North Am. Food Anim. Pract."},{"key":"10.1016\/j.ymthe.2025.02.038_bib53","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1080\/22221751.2021.1903343","article-title":"High dose of vesicular stomatitis virus-vectored Ebola virus vaccine causes vesicular disease in swine without horizontal transmission","volume":"10","author":"Morozov","year":"2021","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.ymthe.2025.02.038_bib54","doi-asserted-by":"crossref","first-page":"3938","DOI":"10.1016\/j.vaccine.2017.06.022","article-title":"Oral vaccination of wildlife against rabies: Differences among host species in vaccine uptake efficiency","volume":"35","author":"Vos","year":"2017","journal-title":"Vaccine"},{"key":"10.1016\/j.ymthe.2025.02.038_bib55","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12917-018-1417-0","article-title":"Safety studies with the oral rabies virus vaccine strain SPBN GASGAS in the small Indian mongoose (Herpestes auropunctatus)","volume":"14","author":"Ortmann","year":"2018","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.ymthe.2025.02.038_bib56","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.chom.2022.07.014","article-title":"Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies","volume":"30","author":"Ng","year":"2022","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ymthe.2025.02.038_bib57","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.abp8632","article-title":"Regional specification of oral mucosal immunity","volume":"7","author":"Williams","year":"2022","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib58","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/nri3738","article-title":"Regional specialization within the intestinal immune system","volume":"14","author":"Mowat","year":"2014","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib59","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.immuni.2023.04.002","article-title":"M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer's patch","volume":"56","author":"Torow","year":"2023","journal-title":"Immunity"},{"key":"10.1016\/j.ymthe.2025.02.038_bib60","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00829-21","article-title":"Toll-Like Receptor 4 Regulates Rabies Virus-Induced Humoral Immunity through Recruitment of Conventional Type 2 Dendritic Cells to Lymph Organs","volume":"95","author":"Chen","year":"2021","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib61","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.cell.2010.01.022","article-title":"Pattern recognition receptors and inflammation","volume":"140","author":"Takeuchi","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.ymthe.2025.02.038_bib62","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1146\/annurev-immunol-101819-025146","article-title":"Dendritic Cell Regulation of T Helper Cells","volume":"39","author":"Yin","year":"2021","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib63","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.4049\/jimmunol.1100853","article-title":"Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T\u00a0cell program but cannot complete ultimate effector differentiation","volume":"187","author":"Goenka","year":"2011","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib64","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.immuni.2014.10.004","article-title":"T follicular helper cell differentiation, function, and roles in disease","volume":"41","author":"Crotty","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.ymthe.2025.02.038_bib65","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1128\/MCB.00434-12","article-title":"Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured \"miniguts\"","volume":"32","author":"de Lau","year":"2012","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib66","article-title":"Single Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells","author":"Surve","year":"2023","journal-title":"bioRxiv."},{"key":"10.1016\/j.ymthe.2025.02.038_bib67","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/nature08529","article-title":"Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response","volume":"462","author":"Hase","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.ymthe.2025.02.038_bib68","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.3390\/v14061127","article-title":"Characterization of Immune Response Diversity in Rodents Vaccinated with a Vesicular Stomatitis Virus Vectored COVID-19 Vaccine","volume":"14","author":"Wang","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.ymthe.2025.02.038_bib69","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0022-1759(97)00212-3","article-title":"Development of a fluorescent antibody virus neutralisation test (FAVN test) for the quantitation of rabies-neutralising antibody","volume":"212","author":"Cliquet","year":"1998","journal-title":"J.\u00a0Immunol. Methods"},{"key":"10.1016\/j.ymthe.2025.02.038_bib70","article-title":"Clinical Characteristics of Immune Response in Asymptomatic Carriers and Symptomatic Patients With COVID-19","volume":"13","author":"Li","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib71","doi-asserted-by":"crossref","first-page":"e02154-16","DOI":"10.1128\/JVI.02154-16","article-title":"Chikungunya, Influenza, Nipah, and Semliki Forest Chimeric Viruses with Vesicular Stomatitis Virus: Actions in the Brain","volume":"91","author":"van den Pol","year":"2017","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib72","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1128\/JVI.76.3.1309-1327.2002","article-title":"Relative neurotropism of a recombinant rhabdovirus expressing a green fluorescent envelope glycoprotein","volume":"76","author":"van den Pol","year":"2002","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib73","doi-asserted-by":"crossref","first-page":"8039","DOI":"10.1128\/JVI.77.14.8039-8047.2003","article-title":"Vesicular stomatitis virus glycoprotein is a determinant of pathogenesis in swine, a natural host","volume":"77","author":"Martinez","year":"2003","journal-title":"J.\u00a0Virol."},{"key":"10.1016\/j.ymthe.2025.02.038_bib74","doi-asserted-by":"crossref","first-page":"R106","DOI":"10.1186\/gb-2010-11-10-r106","article-title":"Differential expression analysis for sequence count data","volume":"11","author":"Anders","year":"2010","journal-title":"Genome Biol."}],"container-title":["Molecular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001625001285?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525001625001285?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T04:04:20Z","timestamp":1775102660000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525001625001285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":74,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S1525001625001285"],"URL":"https:\/\/doi.org\/10.1016\/j.ymthe.2025.02.038","relation":{},"ISSN":["1525-0016"],"issn-type":[{"value":"1525-0016","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A VSV-based oral rabies vaccine was sentineled by Peyer\u2019s patches and induced a timely and durable immune response","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ymthe.2025.02.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The American Society of Gene and Cell Therapy. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}