{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T22:40:12Z","timestamp":1762641612370,"version":"build-2065373602"},"reference-count":73,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-12-2-0012"],"award-info":[{"award-number":["W81XWH-12-2-0012"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AG068990","AG069265","OD025181","U01 AG024904"],"award-info":[{"award-number":["AG068990","AG069265","OD025181","U01 AG024904"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000070","name":"National Institute of Biomedical Imaging and Bioengineering","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000070","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007333","name":"Alzheimer's Disease Neuroimaging Initiative","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007333","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Reports"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.ynirp.2025.100255","type":"journal-article","created":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T10:06:57Z","timestamp":1742724417000},"page":"100255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Functional redundancy of the posterior hippocampi is selectively disrupted in non-demented older adults with \u03b2-amyloid deposition"],"prefix":"10.1016","volume":"5","author":[{"given":"Jenna K.","family":"Blujus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael W.","family":"Cole","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3700-4270","authenticated-orcid":false,"given":"Elena K.","family":"Festa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen L.","family":"Buka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen P.","family":"Salloway","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8258-5206","authenticated-orcid":false,"given":"William C.","family":"Heindel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwamee","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ynirp.2025.100255_bib1","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1212\/WNL.0000000000005303","article-title":"Resistance vs resilience to Alzheimer disease: clarifying terminology for preclinical studies","volume":"90","author":"Arenaza-Urquijo","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.ynirp.2025.100255_bib2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.media.2007.06.004","article-title":"Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain","volume":"12","author":"Avants","year":"2008","journal-title":"Med. Image Anal."},{"key":"10.1016\/j.ynirp.2025.100255_bib3","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1002\/ana.22333","article-title":"Amyloid-beta associated cortical thinning in clinically normal elderly","volume":"69","author":"Becker","year":"2011","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib4","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.neuroimage.2007.04.042","article-title":"A component based noise correction method (CompCor) for BOLD and perfusion based fMRI","volume":"37","author":"Behzadi","year":"2007","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib5","doi-asserted-by":"crossref","first-page":"E4502","DOI":"10.1073\/pnas.1317918110","article-title":"Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease","volume":"110","author":"Benzinger","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ynirp.2025.100255_bib6","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1093\/brain\/awab114","article-title":"Early stages of tau pathology and its associations with functional connectivity, atrophy and memory","volume":"144","author":"Berron","year":"2021","journal-title":"Brain"},{"volume":"vol. 792","year":"1992","author":"Billinton","key":"10.1016\/j.ynirp.2025.100255_bib7"},{"key":"10.1016\/j.ynirp.2025.100255_bib8","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.ynirp.2025.100255_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1440.011","article-title":"The brain's default network: anatomy, function, and relevance to disease","volume":"1124","author":"Buckner","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.ynirp.2025.100255_bib10","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuroimage.2017.03.020","article-title":"Benchmarking of participant-level confound regression strategies for the control of motion artifact in studies of functional connectivity","volume":"154","author":"Ciric","year":"2017","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib11","doi-asserted-by":"crossref","first-page":"8988","DOI":"10.1523\/JNEUROSCI.0536-12.2012","article-title":"Global connectivity of prefrontal cortex predicts cognitive control and intelligence","volume":"32","author":"Cole","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ynirp.2025.100255_bib12","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1038\/nn.3470","article-title":"Multi-task connectivity reveals flexible hubs for adaptive task control","volume":"16","author":"Cole","year":"2013","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ynirp.2025.100255_bib13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/(SICI)1099-1492(199706\/08)10:4\/5<171::AID-NBM453>3.0.CO;2-L","article-title":"Software tools for analysis and visualization of fMRI data","volume":"10","author":"Cox","year":"1997","journal-title":"NMR Biomed."},{"key":"10.1016\/j.ynirp.2025.100255_bib14","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s11682-012-9186-z","article-title":"Development and assessment of a composite score for memory in the Alzheimer's Disease Neuroimaging Initiative (ADNI)","volume":"6","author":"Crane","year":"2012","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.ynirp.2025.100255_bib15","doi-asserted-by":"crossref","DOI":"10.1002\/hbm.26634","article-title":"Small vessel disease and cognitive reserve oppositely modulate global network redundancy and cognitive function: a study in middle-to-old aged community participants","volume":"45","author":"Cui","year":"2024","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.ynirp.2025.100255_bib16","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1006\/nimg.1998.0395","article-title":"Cortical surface-based analysis. I. Segmentation and surface reconstruction","volume":"9","author":"Dale","year":"1999","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib17","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/ana.26168","article-title":"Longitudinal changes in hippocampal network connectivity in alzheimer's disease","volume":"90","author":"Dautricourt","year":"2021","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib18","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/207305","article-title":"Redundancy as a graph-based index of frequency specific MEG functional connectivity","volume":"2012","author":"Di Lanzo","year":"2012","journal-title":"Comput. Math. Methods Med."},{"key":"10.1016\/j.ynirp.2025.100255_bib19","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41592-018-0235-4","article-title":"fMRIPrep: a robust preprocessing pipeline for functional MRI","volume":"16","author":"Esteban","year":"2019","journal-title":"Nat. Methods"},{"key":"10.1016\/j.ynirp.2025.100255_bib20","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1212\/WNL.0000000000003711","article-title":"Left frontal cortex connectivity underlies cognitive reserve in prodromal Alzheimer disease","volume":"88","author":"Franzmeier","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.ynirp.2025.100255_bib21","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1093\/brain\/awy008","article-title":"Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease","volume":"141","author":"Franzmeier","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.ynirp.2025.100255_bib22","doi-asserted-by":"crossref","first-page":"457","DOI":"10.3233\/JAD-142547","article-title":"Increased functional connectivity in the default mode network in mild cognitive impairment: a maladaptive compensatory mechanism associated with poor semantic memory performance","volume":"45","author":"Gardini","year":"2015","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.ynirp.2025.100255_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2021.102917","article-title":"Alterations of dynamic redundancy of functional brain subnetworks in Alzheimer's disease and major depression disorders","volume":"33","author":"Ghanbari","year":"2022","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.ynirp.2025.100255_bib24","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.1002\/hbm.26257","article-title":"Accumulation of network redundancy marks the early stage of Alzheimer's disease","volume":"44","author":"Ghanbari","year":"2023","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.ynirp.2025.100255_bib25","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s11682-012-9176-1","article-title":"A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment","volume":"6","author":"Gibbons","year":"2012","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.ynirp.2025.100255_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3389\/fninf.2011.00013","article-title":"Nipype: a flexible, lightweight and extensible neuroimaging data processing framework in python","volume":"5","author":"Gorgolewski","year":"2011","journal-title":"Front. Neuroinf."},{"key":"10.1016\/j.ynirp.2025.100255_bib27","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuroimage.2009.06.060","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"Greve","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib28","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/(SICI)1099-1166(199906)14:6<481::AID-GPS959>3.0.CO;2-5","article-title":"Rates of dementia in three ethnoracial groups","volume":"14","author":"Gurland","year":"1999","journal-title":"Int. J. Geriatr. Psychiatr."},{"key":"10.1016\/j.ynirp.2025.100255_bib29","doi-asserted-by":"crossref","first-page":"12686","DOI":"10.1523\/JNEUROSCI.3189-09.2009","article-title":"Disruption of functional connectivity in clinically normal older adults harboring amyloid burden","volume":"29","author":"Hedden","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ynirp.2025.100255_bib30","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.neuron.2013.01.002","article-title":"Vulnerable neural systems and the borderland of brain aging and neurodegeneration","volume":"77","author":"Jagust","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.ynirp.2025.100255_bib31","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1006\/nimg.2002.1132","article-title":"Improved optimization for the robust and accurate linear registration and motion correction of brain images","volume":"17","author":"Jenkinson","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib32","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1093\/brain\/awv338","article-title":"Cascading network failure across the Alzheimer's disease spectrum","volume":"139","author":"Jones","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.ynirp.2025.100255_bib33","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/ana.410230206","article-title":"Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques","volume":"23","author":"Katzman","year":"1988","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib34","first-page":"76","article-title":"Evaluation of noisy data","volume":"1","author":"Lanczos","year":"1964","journal-title":"J. Soc. Ind. Appl. Math. B Numer. Anal."},{"key":"10.1016\/j.ynirp.2025.100255_bib35","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.neurobiolaging.2021.09.002","article-title":"& for the Alzheimer's Disease Neuroimaging, I. The association between hippocampal volume and memory in pathological aging is mediated by functional redundancy","volume":"108","author":"Langella","year":"2021","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.ynirp.2025.100255_bib36","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/s41398-020-01166-w","article-title":"Lower functional hippocampal redundancy in mild cognitive impairment","volume":"11","author":"Langella","year":"2021","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.ynirp.2025.100255_bib37","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1148\/radiol.15141700","article-title":"Disrupted functional brain connectome in patients with posttraumatic stress disorder","volume":"276","author":"Lei","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.ynirp.2025.100255_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.knosys.2022.109466","article-title":"Longitudinal study of early mild cognitive impairment via similarity-constrained group learning and self-attention based SBi-LSTM","volume":"254","author":"Lei","year":"2022","journal-title":"Knowl. Base Syst."},{"key":"10.1016\/j.ynirp.2025.100255_bib39","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/7839536","article-title":"Functional evolving patterns of cortical networks in progression of alzheimer's disease: a graph-based resting-state fMRI study","volume":"2020","author":"Li","year":"2020","journal-title":"Neural Plast."},{"key":"10.1016\/j.ynirp.2025.100255_bib40","doi-asserted-by":"crossref","first-page":"6550","DOI":"10.1523\/JNEUROSCI.3711-11.2012","article-title":"Differential connectivity of perirhinal and parahippocampal cortices within human hippocampal subregions revealed by high-resolution functional imaging","volume":"32","author":"Libby","year":"2012","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ynirp.2025.100255_bib41","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","article-title":"Dementia prevention, intervention, and care: 2020 report of the Lancet Commission","volume":"396","author":"Livingston","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.ynirp.2025.100255_bib42","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s00415-015-7750-3","article-title":"Functional connectome assessed using graph theory in drug-naive Parkinson's disease","volume":"262","author":"Luo","year":"2015","journal-title":"J. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib43","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1093\/brain\/awz154","article-title":"Alzheimer's pathology targets distinct memory networks in the ageing brain","volume":"142","author":"Maass","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.ynirp.2025.100255_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropsychologia.2021.108138","article-title":"Individual differences in the relationship between episodic detail generation and resting state functional connectivity vary with age","volume":"166","author":"Matijevic","year":"2022","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.ynirp.2025.100255_bib45","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1093\/cercor\/bhr025","article-title":"Relationships between beta-amyloid and functional connectivity in different components of the default mode network in aging","volume":"21","author":"Mormino","year":"2011","journal-title":"Cerebr. Cortex"},{"key":"10.1016\/j.ynirp.2025.100255_bib46","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0140-6736(00)03589-3","article-title":"Pathological correlates of late-onset dementia in a multicentre, community-based population in england and wales. Neuropathology group of the medical research council cognitive function and ageing study (MRC CFAS)","volume":"357","author":"Aging","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.ynirp.2025.100255_bib47","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1016\/j.neuroimage.2010.10.027","article-title":"beta-Amyloid affects frontal and posterior brain networks in normal aging","volume":"54","author":"Oh","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib48","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1093\/cercor\/bht017","article-title":"Association of gray matter atrophy with age, beta-amyloid, and cognition in aging","volume":"24","author":"Oh","year":"2014","journal-title":"Cerebr. Cortex"},{"key":"10.1016\/j.ynirp.2025.100255_bib49","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/hbm.22173","article-title":"Covarying alterations in Abeta deposition, glucose metabolism, and gray matter volume in cognitively normal elderly","volume":"35","author":"Oh","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.ynirp.2025.100255_bib50","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1093\/brain\/aww108","article-title":"Dynamic relationships between age, amyloid-beta deposition, and glucose metabolism link to the regional vulnerability to Alzheimer's disease","volume":"139","author":"Oh","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.ynirp.2025.100255_bib51","doi-asserted-by":"crossref","first-page":"e197","DOI":"10.1212\/WNL.0000000000004829","article-title":"Multiple pathways of reserve simultaneously present in cognitively normal older adults","volume":"90","author":"Oh","year":"2018","journal-title":"Neurology"},{"key":"10.1016\/j.ynirp.2025.100255_bib52","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1093\/cercor\/bht076","article-title":"Is verbal episodic memory in elderly with amyloid deposits preserved through altered neuronal function?","volume":"24","author":"Ossenkoppele","year":"2014","journal-title":"Cerebr. Cortex"},{"key":"10.1016\/j.ynirp.2025.100255_bib53","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1038\/s41467-017-01150-x","article-title":"Earliest accumulation of beta-amyloid occurs within the default-mode network and concurrently affects brain connectivity","volume":"8","author":"Palmqvist","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ynirp.2025.100255_bib54","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","article-title":"Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion","volume":"59","author":"Power","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib55","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.neuroimage.2013.08.048","article-title":"Methods to detect, characterize, and remove motion artifact in resting state fMRI","volume":"84","author":"Power","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib56","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/1531-8249(199903)45:3<358::AID-ANA12>3.0.CO;2-X","article-title":"Tangles and plaques in nondemented aging and \"preclinical\" Alzheimer's disease","volume":"45","author":"Price","year":"1999","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib57","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.neuroimage.2009.12.025","article-title":"Impairment and compensation coexist in amnestic MCI default mode network","volume":"50","author":"Qi","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib58","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1038\/nrn3338","article-title":"Two cortical systems for memory-guided behaviour","volume":"13","author":"Ranganath","year":"2012","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ynirp.2025.100255_bib59","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1038\/s41593-019-0510-4","article-title":"Advancing functional connectivity research from association to causation","volume":"22","author":"Reid","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ynirp.2025.100255_bib60","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.neurobiolaging.2016.03.016","article-title":"Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease","volume":"42","author":"Rieckmann","year":"2016","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.ynirp.2025.100255_bib61","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","article-title":"Complex network measures of brain connectivity: uses and interpretations","volume":"52","author":"Rubinov","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2021.117737","article-title":"Accrual of functional redundancy along the lifespan and its effects on cognition","volume":"229","author":"Sadiq","year":"2021","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib63","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1162\/jocn_a_01580","article-title":"Combining multiple functional connectivity methods to improve causal inferences","volume":"33","author":"Sanchez-Romero","year":"2021","journal-title":"J. Cognit. Neurosci."},{"key":"10.1016\/j.ynirp.2025.100255_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116290","article-title":"A set of functionally-defined brain regions with improved representation of the subcortex and cerebellum","volume":"206","author":"Seitzman","year":"2020","journal-title":"Neuroimage"},{"key":"10.1016\/j.ynirp.2025.100255_bib65","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/geronb\/gbt133","article-title":"The role of early-life educational quality and literacy in explaining racial disparities in cognition in late life","volume":"70","author":"Sisco","year":"2015","journal-title":"J. Gerontol. B Psychol. Sci. Soc. Sci."},{"key":"10.1016\/j.ynirp.2025.100255_bib66","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/nrneurol.2012.241","article-title":"Preclinical Alzheimer disease-the challenges ahead","volume":"9","author":"Sperling","year":"2013","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib67","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/s42003-024-06392-2","article-title":"Age-related differences in network controllability are mitigated by redundancy in large-scale brain networks","volume":"7","author":"Stanford","year":"2024","journal-title":"Commun. Biol."},{"key":"10.1016\/j.ynirp.2025.100255_bib68","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3233\/JAD-150778","article-title":"A meta-analysis of alzheimer's disease incidence and prevalence comparing african-Americans and caucasians","volume":"50","author":"Steenland","year":"2016","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.ynirp.2025.100255_bib69","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1017\/S1355617702813248","article-title":"What is cognitive reserve? Theory and research application of the reserve concept","volume":"8","author":"Stern","year":"2002","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"10.1016\/j.ynirp.2025.100255_bib70","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/ana.410320311","article-title":"Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease","volume":"32","author":"Stern","year":"1992","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib71","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1001\/archneurol.2009.272","article-title":"Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: cognitive decline associated with Abeta deposition","volume":"66","author":"Storandt","year":"2009","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.ynirp.2025.100255_bib72","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s11357-023-00943-x","article-title":"Sex difference in brain functional connectivity of hippocampus in Alzheimer's disease","volume":"46","author":"Williamson","year":"2024","journal-title":"Geroscience"},{"key":"10.1016\/j.ynirp.2025.100255_bib73","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.f7051","article-title":"Effect of socioeconomic disparities on incidence of dementia among biracial older adults: prospective study","volume":"347","author":"Yaffe","year":"2013","journal-title":"BMJ"}],"container-title":["NeuroImage: Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666956025000236?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666956025000236?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T22:27:23Z","timestamp":1762640843000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666956025000236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":73,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S2666956025000236"],"URL":"https:\/\/doi.org\/10.1016\/j.ynirp.2025.100255","relation":{},"ISSN":["2666-9560"],"issn-type":[{"type":"print","value":"2666-9560"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional redundancy of the posterior hippocampi is selectively disrupted in non-demented older adults with \u03b2-amyloid deposition","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ynirp.2025.100255","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100255"}}