{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T23:56:07Z","timestamp":1776297367900,"version":"3.50.1"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004156","name":"Mahidol University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004156","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["NeuroImage: Reports"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.ynirp.2025.100314","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T06:14:07Z","timestamp":1767680047000},"page":"100314","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Volumetric brain analysis and associated retinal thinning in autosomal dominant optic atrophy patients"],"prefix":"10.1016","volume":"6","author":[{"given":"Punpath","family":"Pajareeyapong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sittaya","family":"Buathong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sasi","family":"Thammasarnsophon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanchalika","family":"Sathianvichitr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natthapon","family":"Rattanathamsakul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akarawit","family":"Eiamsamarng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niphon","family":"Chirapapaisan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5055-0711","authenticated-orcid":false,"given":"Chanon","family":"Ngamsombat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ynirp.2025.100314_bib1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1093\/brain\/awm298","article-title":"OPA1 mutations induce mitochondrial DNA instability and optic atrophy \u2018plus\u2019 phenotypes","volume":"131","author":"Amati-Bonneau","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.ynirp.2025.100314_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2014.05.034","article-title":"Early macular retinal ganglion cell loss in dominant optic atrophy: genotype-phenotype correlation","volume":"158","author":"Barboni","year":"2014","journal-title":"Am. J. Ophthalmol."},{"issue":"4","key":"10.1016\/j.ynirp.2025.100314_bib3","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00401-004-0970-8","article-title":"OPA1, associated with autosomal dominant optic atrophy, is widely expressed in the human brain","volume":"109","author":"Bette","year":"2005","journal-title":"Acta Neuropathol."},{"issue":"5","key":"10.1016\/j.ynirp.2025.100314_bib4","doi-asserted-by":"crossref","first-page":"e85","DOI":"10.1016\/j.jcjo.2015.05.019","article-title":"Retinal nerve fibre layer defect associated with MELAS syndrome","volume":"50","author":"Cho","year":"2015","journal-title":"Can. J. Ophthalmol."},{"issue":"6","key":"10.1016\/j.ynirp.2025.100314_bib5","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/ICU.0000000000000314","article-title":"Dominant optic atrophy: updates on the pathophysiology and clinical manifestations of the optic atrophy 1 mutation","volume":"27","author":"Chun","year":"2016","journal-title":"Curr. Opin. Ophthalmol."},{"issue":"12","key":"10.1016\/j.ynirp.2025.100314_bib6","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1007\/s00417-018-4153-z","article-title":"Mitochondrial pathophysiology beyond the retinal ganglion cell: occipital GABA is decreased in autosomal dominant optic neuropathy","volume":"256","author":"d'Almeida","year":"2018","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"issue":"6","key":"10.1016\/j.ynirp.2025.100314_bib7","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00401-016-1609-2","article-title":"Glaucoma: the retina and beyond","volume":"132","author":"Davis","year":"2016","journal-title":"Acta Neuropathol."},{"issue":"2","key":"10.1016\/j.ynirp.2025.100314_bib8","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/sj.ki.5002736","article-title":"Retinal atrophy associated with FSGS in a patient with MELAS syndrome","volume":"74","author":"Deva","year":"2008","journal-title":"Kidney Int."},{"issue":"2","key":"10.1016\/j.ynirp.2025.100314_bib9","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.neuroimage.2012.01.021","article-title":"FreeSurfer","volume":"62","author":"Fischl","year":"2012","journal-title":"Neuroimage"},{"issue":"2","key":"10.1016\/j.ynirp.2025.100314_bib10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s13311-012-0161-6","article-title":"Neuroimaging in mitochondrial disorders","volume":"10","author":"Gropman","year":"2013","journal-title":"Neurotherapeutics"},{"issue":"1","key":"10.1016\/j.ynirp.2025.100314_bib11","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.exer.2006.09.013","article-title":"Chronic ocular hypertension induces dendrite pathology in the lateral geniculate nucleus of the brain","volume":"84","author":"Gupta","year":"2007","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ynirp.2025.100314_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2021.630898","article-title":"Progression of visual pathway degeneration in primary open-angle glaucoma: a longitudinal study","volume":"15","author":"Haykal","year":"2021","journal-title":"Front. Hum. Neurosci."},{"issue":"3","key":"10.1016\/j.ynirp.2025.100314_bib13","doi-asserted-by":"crossref","first-page":"820","DOI":"10.2214\/AJR.05.0180","article-title":"Chronic progressive external ophthalmoplegia: MR spectroscopy and MR diffusion studies in the brain","volume":"187","author":"Heidenreich","year":"2006","journal-title":"Am. J. Roentgenol."},{"issue":"5","key":"10.1016\/j.ynirp.2025.100314_bib14","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0960-8966(94)00080-S","article-title":"Chronic progressive external ophthalmoplegia with ragged-red fibers: clinical, morphological and genetic investigations in 43 patients","volume":"5","author":"Lafor\u00eat","year":"1995","journal-title":"Neuromuscul. Disord."},{"key":"10.1016\/j.ynirp.2025.100314_bib15","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1750-1172-7-46","article-title":"Dominant optic atrophy","volume":"7","author":"Lenaers","year":"2012","journal-title":"Orphanet J. Rare Dis."},{"issue":"1","key":"10.1016\/j.ynirp.2025.100314_bib16","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1136\/bjo.69.1.63","article-title":"Retinal pathology in the Kearns-Sayre syndrome","volume":"69","author":"McKechnie","year":"1985","journal-title":"Br. J. Ophthalmol."},{"issue":"5","key":"10.1016\/j.ynirp.2025.100314_bib17","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1007\/s00415-015-7696-5","article-title":"Distributed abnormalities of brain white matter architecture in patients with dominant optic atrophy and OPA1 mutations","volume":"262","author":"Rocca","year":"2015","journal-title":"J. Neurol."},{"issue":"1","key":"10.1016\/j.ynirp.2025.100314_bib18","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jns.2015.01.008","article-title":"Neuroradiological findings expand the phenotype of <em>OPA1<\/em>-related mitochondrial dysfunction","volume":"349","author":"Roubertie","year":"2015","journal-title":"J. Neurol. Sci."},{"issue":"3","key":"10.1016\/j.ynirp.2025.100314_bib19","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1093\/brain\/awv396","article-title":"Longitudinal evidence for anterograde trans-synaptic degeneration after optic neuritis","volume":"139","author":"Tur","year":"2016","journal-title":"Brain"},{"issue":"10","key":"10.1016\/j.ynirp.2025.100314_bib20","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1097\/CM9.0000000000000262","article-title":"Optical coherence tomography findings in chronic progressive external ophthalmoplegia","volume":"132","author":"Wu","year":"2019","journal-title":"Chin Med J (Engl)."},{"issue":"15","key":"10.1016\/j.ynirp.2025.100314_bib21","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1093\/hmg\/ddq209","article-title":"OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules","volume":"19","author":"Yu-Wai-Man","year":"2010","journal-title":"Hum. Mol. Genet."},{"issue":"Pt 3","key":"10.1016\/j.ynirp.2025.100314_bib22","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1093\/brain\/awq007","article-title":"Multi-system neurological disease is common in patients with OPA1 mutations","volume":"133","author":"Yu-Wai-Man","year":"2010","journal-title":"Brain"},{"issue":"5","key":"10.1016\/j.ynirp.2025.100314_bib23","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1038\/eye.2011.2","article-title":"Pattern of retinal ganglion cell loss in dominant optic atrophy due to OPA1 mutations","volume":"25","author":"Yu-Wai-Man","year":"2011","journal-title":"Eye"}],"container-title":["NeuroImage: Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666956025000820?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666956025000820?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T23:16:53Z","timestamp":1776295013000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666956025000820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S2666956025000820"],"URL":"https:\/\/doi.org\/10.1016\/j.ynirp.2025.100314","relation":{},"ISSN":["2666-9560"],"issn-type":[{"value":"2666-9560","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Volumetric brain analysis and associated retinal thinning in autosomal dominant optic atrophy patients","name":"articletitle","label":"Article Title"},{"value":"NeuroImage: Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ynirp.2025.100314","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100314"}}