{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T03:37:06Z","timestamp":1771472226565,"version":"3.50.1"},"reference-count":111,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T00:00:00Z","timestamp":1711756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016651","name":"Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016651","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"NIAAA","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Neurobiology of Stress"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.ynstr.2024.100634","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T01:04:22Z","timestamp":1712279062000},"page":"100634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Predator odor stress reactivity, alcohol drinking and the endocannabinoid system"],"prefix":"10.1016","volume":"30","author":[{"given":"Laura C.","family":"Ornelas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce","family":"Besheer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1964","key":"10.1016\/j.ynstr.2024.100634_bib1","article-title":"Sex-specific maternal programming of corticosteroid-binding globulin by predator odour","volume":"288","author":"Abuaish","year":"2021","journal-title":"Proc. Biol. Sci."},{"issue":"5","key":"10.1016\/j.ynstr.2024.100634_bib2","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1021\/cr0782067","article-title":"Enzymatic pathways that regulate endocannabinoid signaling in the nervous system","volume":"108","author":"Ahn","year":"2008","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ynstr.2024.100634_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2022.834880","article-title":"Sensitivity and resilience to predator stress-enhanced ethanol drinking is associated with sex-dependent differences in stress-regulating systems","volume":"16","author":"Alavi","year":"2022","journal-title":"Front. Behav. Neurosci."},{"issue":"2 and 3-Spec Issue","key":"10.1016\/j.ynstr.2024.100634_bib4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/FBP.0000000000000460","article-title":"The predator odor avoidance model of post-traumatic stress disorder in rats","volume":"30","author":"Albrechet-Souza","year":"2019","journal-title":"Behav. Pharmacol."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s13293-020-00303-w","article-title":"Sex differences in traumatic stress reactivity in rats with and without a history of alcohol drinking","volume":"11","author":"Albrechet-Souza","year":"2020","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.ynstr.2024.100634_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2021.100387","article-title":"Amygdalar endocannabinoids are affected by predator odor stress in a sex-specific manner and modulate acoustic startle reactivity in female rats","volume":"15","author":"Albrechet-Souza","year":"2021","journal-title":"Neurobiol Stress"},{"key":"10.1016\/j.ynstr.2024.100634_bib7","series-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2013"},{"key":"10.1016\/j.ynstr.2024.100634_bib8","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.bbr.2013.03.047","article-title":"Immediate early gene and neuropeptide expression following exposure to the predator odor 2,5-dihydro-2,4,5-trimethylthiazoline (TMT)","volume":"248","author":"Asok","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ynstr.2024.100634_bib9","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.pnpbp.2018.11.007","article-title":"Endocannabinoid interactions in the regulation of acquisition of contextual conditioned fear","volume":"90","author":"Balogh","year":"2019","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib10","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.biopsych.2022.12.003","article-title":"Oxytocin reduces sensitized stress-induced alcohol Relapse in a model of posttraumatic stress disorder and alcohol Use disorder Comorbidity","volume":"94","author":"Becker","year":"2023","journal-title":"Biol. Psychiatr."},{"issue":"7","key":"10.1016\/j.ynstr.2024.100634_bib11","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.biopsych.2020.01.015","article-title":"2-Arachidonoylglycerol modulation of anxiety and stress adaptation: from Grass Roots to novel Therapeutics","volume":"88","author":"Bedse","year":"2020","journal-title":"Biol. Psychiatr."},{"issue":"8","key":"10.1016\/j.ynstr.2024.100634_bib12","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.biopsych.2018.04.018","article-title":"The lateral Habenula Directs coping styles under Conditions of stress via Recruitment of the endocannabinoid system","volume":"84","author":"Berger","year":"2018","journal-title":"Biol. Psychiatr."},{"key":"10.1016\/j.ynstr.2024.100634_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2022.903100","article-title":"Trauma Disrupts reinforcement learning in rats-A novel animal model of chronic stress exposure","volume":"16","author":"Bielawski","year":"2022","journal-title":"Front. Behav. Neurosci."},{"issue":"2","key":"10.1016\/j.ynstr.2024.100634_bib14","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1037\/0735-7044.117.2.360","article-title":"Failure to produce conditioning with low-dose trimethylthiazoline or cat feces as unconditioned stimuli","volume":"117","author":"Blanchard","year":"2003","journal-title":"Behav. Neurosci."},{"issue":"2","key":"10.1016\/j.ynstr.2024.100634_bib15","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1124\/pr.112.006387","article-title":"Chemical probes of endocannabinoid metabolism","volume":"65","author":"Blankman","year":"2013","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ynstr.2024.100634_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2022.114090","article-title":"Stress resilience-associated behaviors following predator scent stress are accompanied by upregulated nucleus accumbens mGlu5 transcription in female Sprague Dawley rats","volume":"436","author":"Blount","year":"2023","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ynstr.2024.100634_bib17","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms14782","article-title":"Endocannabinoid signalling modulates susceptibility to traumatic stress exposure","volume":"8","author":"Bluett","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ynstr.2024.100634_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.yhbeh.2020.104806","article-title":"Intergenerational effects of paternal predator cue exposure on behavior, stress reactivity, and neural gene expression","volume":"124","author":"Brass","year":"2020","journal-title":"Horm. Behav."},{"key":"10.1016\/j.ynstr.2024.100634_bib19","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.neuropharm.2017.07.032","article-title":"Susceptibility to traumatic stress sensitizes the dopaminergic response to cocaine and increases motivation for cocaine","volume":"125","author":"Brodnik","year":"2017","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib20","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1038\/s41386-019-0526-1","article-title":"Accelerated development of cocaine-associated dopamine transients and cocaine use vulnerability following traumatic stress","volume":"45","author":"Brodnik","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ynstr.2024.100634_bib21","first-page":"1","article-title":"Enhancement of peripheral fatty acyl ethanolamide signaling prevents stress-induced social avoidance and anxiety-like behaviors in male rats","author":"Carnevali","year":"2023","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ynstr.2024.100634_bib22","series-title":"Trauma-Informed Care in Behavioral Health Services","article-title":"T. SAMHSA\/CSAT treatment Improvement protocols","year":"2014"},{"issue":"9","key":"10.1016\/j.ynstr.2024.100634_bib23","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1001\/jama.1992.03480090092034","article-title":"The concepts of stress and stress system disorders: overview of physical and behavioral homeostasis","volume":"267","author":"Chrousos","year":"1992","journal-title":"JAMA"},{"key":"10.1016\/j.ynstr.2024.100634_bib24","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.neuroscience.2023.11.001","article-title":"Differential c-Fos response in neurocircuits activated by repeated predator stress in male and female C57BL\/6J mice with stress sensitive or resilient alcohol intake phenotypes","volume":"535","author":"Clark","year":"2023","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/j.ynstr.2024.100634_bib25","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.neuropharm.2011.04.023","article-title":"Animal model for PTSD: from clinical concept to translational research","volume":"62","author":"Cohen","year":"2012","journal-title":"Neuropharmacology"},{"issue":"8","key":"10.1016\/j.ynstr.2024.100634_bib26","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.alcohol.2014.07.015","article-title":"Environmental stressors influence limited-access ethanol consumption by C57BL\/6J mice in a sex-dependent manner","volume":"48","author":"Cozzoli","year":"2014","journal-title":"Alcohol"},{"key":"10.1016\/j.ynstr.2024.100634_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2021.102922","article-title":"The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD","volume":"33","author":"Crombie","year":"2022","journal-title":"Neuroimage Clin"},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib28","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1038\/s41598-021-82953-3","article-title":"Early life stress during the neonatal period alters social play and Line1 during the juvenile stage of development","volume":"11","author":"Cuarenta","year":"2021","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.ynstr.2024.100634_bib29","doi-asserted-by":"crossref","first-page":"3211","DOI":"10.1007\/s00213-018-5020-7","article-title":"Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety","volume":"235","author":"Danandeh","year":"2018","journal-title":"Psychopharmacology (Berl)"},{"issue":"9","key":"10.1016\/j.ynstr.2024.100634_bib30","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1016\/j.psyneuen.2013.06.006","article-title":"Animal models in translational studies of PTSD","volume":"38","author":"Daskalakis","year":"2013","journal-title":"Psychoneuroendocrinology"},{"issue":"1\u20132","key":"10.1016\/j.ynstr.2024.100634_bib31","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.brainres.2004.07.079","article-title":"The pattern of brain c-fos mRNA induced by a component of fox odor, 2,5-dihydro-2,4,5-trimethylthiazoline (TMT), in rats, suggests both systemic and processive stress characteristics","volume":"1025","author":"Day","year":"2004","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.ynstr.2024.100634_bib32","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jpsychires.2005.08.002","article-title":"Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review","volume":"40","author":"De Kloet","year":"2006","journal-title":"J. Psychiatr. Res."},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib33","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.neuroimage.2009.05.074","article-title":"The brain and the stress axis: the neural correlates of cortisol regulation in response to stress","volume":"47","author":"Dedovic","year":"2009","journal-title":"Neuroimage"},{"issue":"10","key":"10.1016\/j.ynstr.2024.100634_bib34","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.biopsych.2017.11.019","article-title":"Current status of animal models of posttraumatic stress disorder: behavioral and biological phenotypes, and future challenges in improving translation","volume":"83","author":"Deslauriers","year":"2018","journal-title":"Biol. Psychiatr."},{"key":"10.1016\/j.ynstr.2024.100634_bib35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.alcohol.2018.12.001","article-title":"Sexually divergent changes in select brain proteins and neurosteroid levels after a history of ethanol drinking and intermittent PTSD-like stress exposure in adult C57BL\/6J mice","volume":"83","author":"Devaud","year":"2020","journal-title":"Alcohol"},{"key":"10.1016\/j.ynstr.2024.100634_bib36","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.70","article-title":"Traumatic stress reactivity promotes excessive alcohol drinking and alters the balance of prefrontal cortex-amygdala activity","volume":"3","author":"Edwards","year":"2013","journal-title":"Transl. Psychiatry"},{"issue":"Pt 15","key":"10.1016\/j.ynstr.2024.100634_bib37","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1242\/jeb.028498","article-title":"Aversion- vs fear-inducing properties of 2,4,5-trimethyl-3-thiazoline, a component of fox odor, in comparison with those of butyric acid","volume":"212","author":"Endres","year":"2009","journal-title":"J. Exp. Biol."},{"issue":"4","key":"10.1016\/j.ynstr.2024.100634_bib38","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1037\/0735-7044.119.4.1004","article-title":"Behavioral changes induced in rats by exposure to trimethylthiazoline, a component of fox odor","volume":"119","author":"Endres","year":"2005","journal-title":"Behav. Neurosci."},{"issue":"5","key":"10.1016\/j.ynstr.2024.100634_bib39","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.euroneuro.2018.02.004","article-title":"Chronic treatment with URB597 ameliorates post-stress symptoms in a rat model of PTSD","volume":"28","author":"Fidelman","year":"2018","journal-title":"Eur. Neuropsychopharmacol"},{"key":"10.1016\/j.ynstr.2024.100634_bib40","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.alcohol.2018.02.004","article-title":"Sex differences in the synergistic effect of prior binge drinking and traumatic stress on subsequent ethanol intake and neurochemical responses in adult C57BL\/6J mice","volume":"71","author":"Finn","year":"2018","journal-title":"Alcohol"},{"issue":"16","key":"10.1016\/j.ynstr.2024.100634_bib41","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1002\/cne.24704","article-title":"Ultrastructural localization of cannabinoid CB1 and mGluR5 receptors in the prefrontal cortex and amygdala","volume":"527","author":"Fitzgerald","year":"2019","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ynstr.2024.100634_bib42","first-page":"1","article-title":"Fatty acid amide hydrolase inhibition alleviates anxiety-like symptoms in a rat model used to study post-traumatic stress disorder","author":"Fotio","year":"2023","journal-title":"Psychopharmacology"},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib43","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1152\/physrev.00004.2003","article-title":"Role of endogenous cannabinoids in synaptic signaling","volume":"83","author":"Freund","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ynstr.2024.100634_bib44","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1007\/s00127-016-1208-5","article-title":"The epidemiology of DSM-5 posttraumatic stress disorder in the United States: results from the national epidemiologic survey on alcohol and related conditions-III","volume":"51","author":"Goldstein","year":"2016","journal-title":"Soc. Psychiatr. Psychiatr. Epidemiol."},{"issue":"2","key":"10.1016\/j.ynstr.2024.100634_bib45","doi-asserted-by":"crossref","DOI":"10.35946\/arcr.v40.2.05","article-title":"The role of stress, trauma, and negative affect in alcohol misuse and alcohol use disorder in women","volume":"40","author":"Guinle","year":"2020","journal-title":"Alcohol Res. Curr. Rev."},{"key":"10.1016\/j.ynstr.2024.100634_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2020.110116","article-title":"The endocannabinoid system in the amygdala and modulation of fear","volume":"105","author":"Gunduz-Cinar","year":"2021","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"7","key":"10.1016\/j.ynstr.2024.100634_bib47","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/mp.2012.72","article-title":"Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity","volume":"18","author":"Gunduz-Cinar","year":"2013","journal-title":"Mol. Psychiatr."},{"issue":"19","key":"10.1016\/j.ynstr.2024.100634_bib48","doi-asserted-by":"crossref","first-page":"3053","DOI":"10.1016\/j.neuron.2023.06.023","article-title":"A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction","volume":"111","author":"Gunduz-Cinar","year":"2023","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib49","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s00213-013-3161-2","article-title":"The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats","volume":"230","author":"Haller","year":"2013","journal-title":"Psychopharmacology (Berl)"},{"issue":"9","key":"10.1016\/j.ynstr.2024.100634_bib50","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1111\/j.1460-9568.2004.03704.x","article-title":"Brief exposure to predator odor and resultant anxiety enhances mesocorticolimbic activity and enkephalin expression in CD\u20101 mice","volume":"20","author":"Hebb","year":"2004","journal-title":"Eur. J. Neurosci."},{"issue":"7","key":"10.1016\/j.ynstr.2024.100634_bib51","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1111\/j.1460-9568.2006.05061.x","article-title":"Endocannabinoids modulate stress-induced suppression of hippocampal cell proliferation and activation of defensive behaviours","volume":"24","author":"Hill","year":"2006","journal-title":"Eur. J. Neurosci."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib52","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/npp.2017.162","article-title":"Integrating endocannabinoid signaling and cannabinoids into the biology and treatment of posttraumatic stress disorder","volume":"43","author":"Hill","year":"2018","journal-title":"Neuropsychopharmacology"},{"issue":"15","key":"10.1016\/j.ynstr.2024.100634_bib53","doi-asserted-by":"crossref","first-page":"7006","DOI":"10.1017\/S0033291723002465","article-title":"The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses","volume":"53","author":"Hill","year":"2023","journal-title":"Psychol. Med."},{"issue":"10","key":"10.1016\/j.ynstr.2024.100634_bib54","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1038\/s41386-023-01650-z","article-title":"CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats","volume":"48","author":"Huckleberry","year":"2023","journal-title":"Neuropsychopharmacology"},{"issue":"8","key":"10.1016\/j.ynstr.2024.100634_bib55","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1038\/s41386-020-0696-x","article-title":"Cannabinoid CB2 receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear","volume":"45","author":"Ivy","year":"2020","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ynstr.2024.100634_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2014.12.030","article-title":"TMT predator odor activated neural circuit in C57BL\/6J mice indicates TMT-stress as a suitable model for uncontrollable intense stress","volume":"1599","author":"Janitzky","year":"2015","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.ynstr.2024.100634_bib57","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1177\/1078390311420564","article-title":"Implications of hypothalamic\u2013pituitary\u2013adrenal axis functioning in posttraumatic stress disorder","volume":"17","author":"Jones","year":"2011","journal-title":"J. Am. Psychiatr. Nurses Assoc."},{"issue":"4","key":"10.1016\/j.ynstr.2024.100634_bib58","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1001\/archpsyc.1997.01830160031005","article-title":"Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey","volume":"54","author":"Kessler","year":"1997","journal-title":"Arch. Gen. Psychiatr."},{"issue":"9","key":"10.1016\/j.ynstr.2024.100634_bib59","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1007\/s00213-019-05233-z","article-title":"Oxytocin attenuates stress-induced reinstatement of alcohol seeking behavior in male and female mice","volume":"236","author":"King","year":"2019","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.ynstr.2024.100634_bib60","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.neuropharm.2012.03.024","article-title":"Modulation of pyramidal cell output in the medial prefrontal cortex by mGluR5 interacting with CB1","volume":"66","author":"Kiritoshi","year":"2013","journal-title":"Neuropharmacology"},{"issue":"9","key":"10.1016\/j.ynstr.2024.100634_bib61","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.biopsych.2022.05.012","article-title":"The endocannabinoid 2-arachidonoylglycerol bidirectionally modulates acute and protracted effects of predator odor exposure","volume":"92","author":"Kondev","year":"2022","journal-title":"Biol. Psychiatr."},{"issue":"9","key":"10.1016\/j.ynstr.2024.100634_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.113027","article-title":"Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation","volume":"42","author":"Kondev","year":"2023","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib63","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1037\/a0032266","article-title":"Gender differences in relationships among PTSD severity, drinking motives, and alcohol use in a comorbid alcohol dependence and PTSD sample","volume":"28","author":"Lehavot","year":"2014","journal-title":"Psychol. Addict. Behav."},{"issue":"5","key":"10.1016\/j.ynstr.2024.100634_bib64","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1038\/npp.2015.284","article-title":"Endocannabinoid modulation of predator stress-induced long-term anxiety in rats","volume":"41","author":"Lim","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"12","key":"10.1016\/j.ynstr.2024.100634_bib65","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1038\/nrn4036","article-title":"The endocannabinoid system in guarding against fear, anxiety and stress","volume":"16","author":"Lutz","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib67","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00213-020-05659-w","article-title":"The synthetically produced predator odor 2,5-dihydro-2,4,5-trimethylthiazoline increases alcohol self-administration and alters basolateral amygdala response to alcohol in rats","volume":"238","author":"Makhijani","year":"2021","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.ynstr.2024.100634_bib68","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bbr.2016.03.009","article-title":"Predator-scent stress, ethanol consumption and the opioid system in an animal model of PTSD","volume":"306","author":"Manjoch","year":"2016","journal-title":"Behav. Brain Res."},{"issue":"6","key":"10.1016\/j.ynstr.2024.100634_bib69","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.neuron.2019.12.024","article-title":"Endocannabinoid signaling collapse mediates stress-induced amygdalo-cortical strengthening","volume":"105","author":"Marcus","year":"2020","journal-title":"Neuron"},{"issue":"6","key":"10.1016\/j.ynstr.2024.100634_bib70","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.biopsych.2019.07.034","article-title":"Elevated anandamide, enhanced recall of fear extinction, and attenuated stress responses following inhibition of fatty acid amide hydrolase: a randomized, controlled experimental medicine trial","volume":"87","author":"Mayo","year":"2020","journal-title":"Biol. Psychiatr."},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib71","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.biopsych.2021.07.019","article-title":"Targeting the endocannabinoid system in the treatment of posttraumatic stress disorder: a promising case of preclinical-clinical translation?","volume":"91","author":"Mayo","year":"2022","journal-title":"Biol. Psychiatr."},{"issue":"1\u20132","key":"10.1016\/j.ynstr.2024.100634_bib72","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0166-4328(01)00324-2","article-title":"Not all 'predator odours' are equal: cat odour but not 2,4,5 trimethylthiazoline (TMT; fox odour) elicits specific defensive behaviours in rats","volume":"129","author":"McGregor","year":"2002","journal-title":"Behav. Brain Res."},{"issue":"9","key":"10.1016\/j.ynstr.2024.100634_bib73","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.euroneuro.2012.01.004","article-title":"Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway","volume":"22","author":"McLaughlin","year":"2012","journal-title":"Eur. Neuropsychopharmacol"},{"key":"10.1016\/j.ynstr.2024.100634_bib74","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.bbr.2012.09.053","article-title":"Upregulation of CB(1) receptor binding in the ventromedial prefrontal cortex promotes proactive stress-coping strategies following chronic stress exposure","volume":"237","author":"McLaughlin","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ynstr.2024.100634_bib75","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.neubiorev.2014.02.006","article-title":"A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior","volume":"42","author":"McLaughlin","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"21","key":"10.1016\/j.ynstr.2024.100634_bib76","doi-asserted-by":"crossref","first-page":"7109","DOI":"10.1523\/JNEUROSCI.1054-12.2012","article-title":"Bimodal control of fear-coping strategies by CB(1) cannabinoid receptors","volume":"32","author":"Metna-Laurent","year":"2012","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib77","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/npp.2015.166","article-title":"Neurobiological interactions between stress and the endocannabinoid system","volume":"41","author":"Morena","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"6","key":"10.1016\/j.ynstr.2024.100634_bib78","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/npp.2017.305","article-title":"Enhancing endocannabinoid neurotransmission augments the efficacy of extinction training and ameliorates traumatic stress-induced behavioral alterations in rats","volume":"43","author":"Morena","year":"2018","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"10.1016\/j.ynstr.2024.100634_bib79","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1111\/bph.15341","article-title":"Sex-dependent effects of endocannabinoid modulation of conditioned fear extinction in rats","volume":"178","author":"Morena","year":"2021","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib80","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/syn.10109","article-title":"Fear-like biochemical and behavioral responses in rats to the predator odor, TMT, are dependent on the exposure environment","volume":"46","author":"Morrow","year":"2002","journal-title":"Synapse"},{"key":"10.1016\/j.ynstr.2024.100634_bib81","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.psyneuen.2014.10.012","article-title":"Translational evidence for a role of endocannabinoids in the etiology and treatment of posttraumatic stress disorder","volume":"51","author":"Neumeister","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.ynstr.2024.100634_bib82","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2024.01.001","article-title":"Stress-enhanced ethanol drinking does not increase sensitivity to the effects of a CRF-R1 antagonist on ethanol intake in male and female mice","author":"Nipper","year":"2024","journal-title":"Alcohol"},{"key":"10.1016\/j.ynstr.2024.100634_bib83","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2020.113068","article-title":"Increased alcohol self-administration following exposure to the predator odor TMT in active coping female rats","volume":"402","author":"Ornelas","year":"2021","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ynstr.2024.100634_bib84","doi-asserted-by":"crossref","DOI":"10.1007\/s00213-021-05957-x","article-title":"The role of the nucleus reuniens in regulating contextual conditioning with the predator odor TMT in female rats","author":"Ornelas","year":"2021","journal-title":"Psychopharmacology (Berl)"},{"issue":"Pt A","key":"10.1016\/j.ynstr.2024.100634_bib85","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.neubiorev.2016.12.033","article-title":"The endocannabinoid system as a target for novel anxiolytic drugs","volume":"76","author":"Patel","year":"2017","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.ynstr.2024.100634_bib86","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2021.100293","article-title":"Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex","volume":"14","author":"Pav\u00f3n","year":"2021","journal-title":"Neurobiol Stress"},{"issue":"12","key":"10.1016\/j.ynstr.2024.100634_bib87","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1038\/npp.2012.123","article-title":"Biphasic effects of cannabinoids in anxiety responses: CB1 and GABAB receptors in the balance of GABAergic and glutamatergic neurotransmission","volume":"37","author":"Rey","year":"2012","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib88","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/1534582304265945","article-title":"The neurobiology of conditioned and unconditioned fear: a neurobehavioral system analysis of the amygdala","volume":"3","author":"Rosen","year":"2004","journal-title":"Behav. Cognit. Neurosci. Rev."},{"key":"10.1016\/j.ynstr.2024.100634_bib89","doi-asserted-by":"crossref","first-page":"292","DOI":"10.3389\/fnins.2015.00292","article-title":"The smell of fear: innate threat of 2,5-dihydro-2,4,5-trimethylthiazoline, a single molecule component of a predator odor","volume":"9","author":"Rosen","year":"2015","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib90","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/s41398-018-0265-9","article-title":"A novel rat model of comorbid PTSD and addiction reveals intersections between stress susceptibility and enhanced cocaine seeking with a role for mGlu5 receptors","volume":"8","author":"Schwendt","year":"2018","journal-title":"Transl. Psychiatry"},{"issue":"5","key":"10.1016\/j.ynstr.2024.100634_bib91","first-page":"412","article-title":"Gender differences in individuals with comorbid alcohol dependence and post-traumatic stress disorder","volume":"12","author":"Sonne","year":"2003","journal-title":"Am. J. Addict."},{"key":"10.1016\/j.ynstr.2024.100634_bib92","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3389\/fnbeh.2015.00145","article-title":"Programming of stress-related behavior and epigenetic neural gene regulation in mice offspring through maternal exposure to predator odor","volume":"9","author":"St-Cyr","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.ynstr.2024.100634_bib93","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yhbeh.2017.06.005","article-title":"Maternal programming of sex-specific responses to predator odor stress in adult rats","volume":"94","author":"St-Cyr","year":"2017","journal-title":"Horm. Behav."},{"key":"10.1016\/j.ynstr.2024.100634_bib94","doi-asserted-by":"crossref","first-page":"136","DOI":"10.3389\/fnbeh.2018.00136","article-title":"Maternal predator odor exposure in mice programs adult offspring social behavior and increases stress-induced behaviors in semi-naturalistic and commonly-used laboratory tasks","volume":"12","author":"St-Cyr","year":"2018","journal-title":"Front. Behav. Neurosci."},{"issue":"4","key":"10.1016\/j.ynstr.2024.100634_bib95","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.nlm.2010.09.009","article-title":"Predator odor avoidance as a rodent model of anxiety: learning-mediated consequences beyond the initial exposure","volume":"94","author":"Staples","year":"2010","journal-title":"Neurobiol. Learn. Mem."},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib96","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/sj.tpj.6500466","article-title":"Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice","volume":"8","author":"Steiner","year":"2008","journal-title":"Pharmacogenomics J."},{"issue":"8","key":"10.1016\/j.ynstr.2024.100634_bib97","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.neubiorev.2005.04.008","article-title":"The smell of danger: a behavioral and neural analysis of predator odor-induced fear","volume":"29","author":"Takahashi","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.ynstr.2024.100634_bib98","article-title":"Sex differences in cocaine self-administration by Wistar rats after predator odor exposure","volume":"3","author":"Templeton","year":"2023","journal-title":"Adv Drug Alcohol Res"},{"issue":"2","key":"10.1016\/j.ynstr.2024.100634_bib99","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.expneurol.2006.04.010","article-title":"Acute exposure to predator odor elicits a robust increase in corticosterone and a decrease in activity without altering proliferation in the adult rat hippocampus","volume":"201","author":"Thomas","year":"2006","journal-title":"Exp. Neurol."},{"issue":"4","key":"10.1016\/j.ynstr.2024.100634_bib100","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1037\/adb0000564","article-title":"Bidirectional relationship of posttraumatic stress disorder (PTSD) symptom severity and alcohol use over the course of integrated treatment","volume":"34","author":"Tripp","year":"2020","journal-title":"Psychol. Addict. Behav."},{"issue":"8","key":"10.1016\/j.ynstr.2024.100634_bib101","doi-asserted-by":"crossref","DOI":"10.1111\/gbb.12684","article-title":"Exposure to the predator odor TMT induces early and late differential gene expression related to stress and excitatory synaptic function throughout the brain in male rats","volume":"19","author":"Tyler","year":"2020","journal-title":"Gene Brain Behav."},{"key":"10.1016\/j.ynstr.2024.100634_bib102","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2022.108943","article-title":"The effects of predator odor (TMT) exposure and mGlu(3) NAM pretreatment on behavioral and NMDA receptor adaptations in the brain","volume":"207","author":"Tyler","year":"2022","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.ynstr.2024.100634_bib103","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.neulet.2006.07.026","article-title":"Genetic influences on behavioral and neuroendocrine responses to predator-odor stress in rats","volume":"409","author":"Vendruscolo","year":"2006","journal-title":"Neurosci. Lett."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib104","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1471-4159.2005.03549.x","article-title":"Transient changes in nucleus accumbens amino acid concentrations correlate with individual responsivity to the predator fox odor 2,5-dihydro-2,4,5-trimethylthiazoline","volume":"96","author":"Venton","year":"2006","journal-title":"J. Neurochem."},{"issue":"1","key":"10.1016\/j.ynstr.2024.100634_bib105","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/s41398-020-0806-x","article-title":"Rodent models of post-traumatic stress disorder: behavioral assessment","volume":"10","author":"Verbitsky","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.ynstr.2024.100634_bib106","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/BF00987509","article-title":"Structure-activity relationship of stress-inducing odorants in the rat","volume":"10","author":"Vernet-Maury","year":"1984","journal-title":"J. Chem. Ecol."},{"key":"10.1016\/j.ynstr.2024.100634_bib107","series-title":"Chemical Signals in Vertebrates 6","first-page":"305","article-title":"Repellent effect of trimethyl thiazoline in the wild rat Rattus norvegicus Berkenhout","author":"Vernet-Maury","year":"1992"},{"issue":"5","key":"10.1016\/j.ynstr.2024.100634_bib108","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1037\/0735-7044.114.5.912","article-title":"Predator odor as an unconditioned fear stimulus in rats: elicitation of freezing by trimethylthiazoline, a component of fox feces","volume":"114","author":"Wallace","year":"2000","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.ynstr.2024.100634_bib109","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2020.107979","article-title":"The role of central amygdala corticotropin-releasing factor in predator odor stress-induced avoidance behavior and escalated alcohol drinking in rats","volume":"166","author":"Weera","year":"2020","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.ynstr.2024.100634_bib110","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.janxdis.2012.01.007","article-title":"Impulsive behaviors as an emotion regulation strategy: examining associations between PTSD, emotion dysregulation, and impulsive behaviors among substance dependent inpatients","volume":"26","author":"Weiss","year":"2012","journal-title":"J. Anxiety Disord."},{"key":"10.1016\/j.ynstr.2024.100634_bib111","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1097\/FBP.0000000000000069","article-title":"Animal models of post-traumatic stress disorder and recent neurobiological insights","volume":"25","author":"Whitaker","year":"2014","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.ynstr.2024.100634_bib112","doi-asserted-by":"crossref","DOI":"10.1016\/j.nlm.2023.107758","article-title":"Cannabinoid modulation of corticolimbic activation during extinction learning and fear renewal in adults with posttraumatic stress disorder","volume":"201","author":"Zabik","year":"2023","journal-title":"Neurobiol. Learn. Mem."}],"container-title":["Neurobiology of Stress"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352289524000304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352289524000304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T21:55:29Z","timestamp":1717365329000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352289524000304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":111,"alternative-id":["S2352289524000304"],"URL":"https:\/\/doi.org\/10.1016\/j.ynstr.2024.100634","relation":{},"ISSN":["2352-2895"],"issn-type":[{"value":"2352-2895","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predator odor stress reactivity, alcohol drinking and the endocannabinoid system","name":"articletitle","label":"Article Title"},{"value":"Neurobiology of Stress","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ynstr.2024.100634","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100634"}}