{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:14:58Z","timestamp":1792289698680,"version":"4.4.0"},"reference-count":169,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regulatory Toxicology and Pharmacology"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.yrtph.2018.08.007","type":"journal-article","created":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T13:14:33Z","timestamp":1534511673000},"page":"257-267","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":322,"special_numbering":"C","title":["Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review"],"prefix":"10.1016","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1188-445X","authenticated-orcid":false,"given":"Niels","family":"Hadrup","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoop K.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1741-8406","authenticated-orcid":false,"given":"Katrin","family":"Loeschner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yrtph.2018.08.007_bib1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3109\/00365518109092041","article-title":"Argyria\u2014tissue deposition of silver as selenide","volume":"41","author":"Aaseth","year":"1981","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.yrtph.2018.08.007_bib2","first-page":"74","article-title":"Occupational allergic contact dermatitis to silver and colophonium in a jeweler","volume":"13","author":"Agarwal","year":"2002","journal-title":"Am. J. Contact Dermatitis"},{"key":"10.1016\/j.yrtph.2018.08.007_bib3","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s12011-014-0224-0","article-title":"Increased DNA damage and oxidative stress among silver jewelry workers","volume":"164","author":"Aktepe","year":"2015","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.tox.2011.10.022","article-title":"Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells","volume":"291","author":"Asare","year":"2012","journal-title":"Toxicology"},{"key":"10.1016\/j.yrtph.2018.08.007_bib5","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1021\/nn800596w","article-title":"Cytotoxicity and genotoxicity of silver nanoparticles in human cells","volume":"3","author":"AshaRani","year":"2009","journal-title":"ACS Nano"},{"key":"10.1016\/j.yrtph.2018.08.007_bib6","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1097\/00006534-196606000-00012","article-title":"Organ deposition of silver following silver nitrate therapy of burns","volume":"37","author":"Bader","year":"1966","journal-title":"Plast. Reconstr. Surg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib7","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1001\/archopht.1991.01080060031013","article-title":"Pigmented episcleral mass from argyrosis following strabismus surgery","volume":"109","author":"Bartley","year":"1991","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib8","first-page":"136","article-title":"Selenium and kidney deposits in experimental argyria. Electron microscopy and microanalysis","volume":"30","author":"Berry","year":"1982","journal-title":"Pathol. Biol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib9","first-page":"21","article-title":"Interaction of selenium with copper, silver, and gold salts. Electron microprobe study","volume":"27","author":"Berry","year":"1995","journal-title":"J. Submicr. Cytol. Pathol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib10","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1080\/17435390.2016.1235739","article-title":"Characterization of silver particles in the stratum corneum of healthy subjects and atopic dermatitis patients dermally exposed to a silver-containing garment","volume":"10","author":"Bianco","year":"2016","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.yrtph.2018.08.007_bib11","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1365-2133.1981.tb01706.x","article-title":"Occupational argyria; light and electron microscopic studies and X-ray microanalysis","volume":"104","author":"Bleehen","year":"1981","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib12","first-page":"40","article-title":"Serum and urinary silver levels in thermal injury patients","volume":"101","author":"Boosalis","year":"1987","journal-title":"Surgery"},{"key":"10.1016\/j.yrtph.2018.08.007_bib13","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/0002-9610(71)90143-7","article-title":"Use of 0.5 per cent silver nitrate cream for burns","volume":"121","author":"Bouterie","year":"1971","journal-title":"Am. J. Surg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib14","doi-asserted-by":"crossref","DOI":"10.1111\/jdv.15055","article-title":"Silver absorption and toxicity evaluation of silver wound dressings in 40 patients with chronic wounds","author":"Brouillard","year":"2018","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.5070\/D34W81J7SM","article-title":"Argyria attributed to silvadene application in a patient with dystrophic epidermolysis bullosa","volume":"14","author":"Browning","year":"2008","journal-title":"Dermatol. Online J."},{"key":"10.1016\/j.yrtph.2018.08.007_bib16","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1001\/archderm.1965.01600180089018","article-title":"Localized argyria - II chemical nature of silver containing particles","volume":"92","author":"Buckley","year":"1965","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib17","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1097\/00005373-198207000-00010","article-title":"Leukopenia and silver sulfadiazine","volume":"22","author":"Caffee","year":"1982","journal-title":"J. Trauma"},{"key":"10.1016\/j.yrtph.2018.08.007_bib18","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1001\/archopht.1941.00870110091010","article-title":"Effects of some silver salts on the eye","volume":"25","author":"Calvery","year":"1941","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib19","series-title":"SciFinder","author":"CAS","year":"2018"},{"key":"10.1016\/j.yrtph.2018.08.007_bib20","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0030-4220(78)90402-4","article-title":"Allergy to silver amalgams","volume":"46","author":"Catsakis","year":"1978","journal-title":"Oral Surg. Oral Med. Oral Pathol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib21","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0151-9638(05)79509-0","article-title":"[Topical silver sulfadiazine-induced acute renal failure]","volume":"132","author":"Chaby","year":"2005","journal-title":"Ann. dermatologie v\u00e9n\u00e9r\u00e9ologie"},{"key":"10.1016\/j.yrtph.2018.08.007_bib22","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/00005373-197605000-00013","article-title":"Acute leukopenia as an allergic reaction to silver sulfadiazine in burn patients","volume":"16","author":"Chan","year":"1976","journal-title":"J. Trauma"},{"key":"10.1016\/j.yrtph.2018.08.007_bib23","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1136\/bmj.303.6797.276","article-title":"Serum cholesterol concentration and coronary heart disease in population with low cholesterol concentrations","volume":"303","author":"Chen","year":"1991","journal-title":"BMJ"},{"key":"10.1016\/j.yrtph.2018.08.007_bib24","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3390\/toxics1010036","article-title":"Genotoxicity of silver nanoparticles in lung cells of sprague dawley rats after 12 Weeks of inhalation exposure","volume":"1","author":"Cho","year":"2013","journal-title":"Toxics"},{"key":"10.1016\/j.yrtph.2018.08.007_bib25","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0305-4179(99)00031-5","article-title":"Methemoglobinemia secondary to topical silver nitrate therapy--a case report","volume":"25","author":"Chou","year":"1999","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib26","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/BF02519367","article-title":"Trace element intake and excretion in the Italian population","volume":"37","author":"Clemente","year":"1977","journal-title":"J. Radioanal. Chem."},{"key":"10.1016\/j.yrtph.2018.08.007_bib27","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0305-4179(92)90067-5","article-title":"Do burn patients have a silver lining?","volume":"18","author":"Coombs","year":"1992","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib28","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0022-3476(69)80046-6","article-title":"Methemoglobinemia with silver nitrate therapy of a burn; report of a case","volume":"74","author":"Cushing","year":"1969","journal-title":"J. Pediatr."},{"key":"10.1016\/j.yrtph.2018.08.007_bib29","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00418-009-0670-5","article-title":"In vivo liberation of silver ions from metallic silver surfaces","volume":"133","author":"Danscher","year":"2010","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib30","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.tox.2013.11.012","article-title":"Genotoxicity of silver and titanium dioxide nanoparticles in bone marrow cells of rats in vivo","volume":"315","author":"Dobrzy\u0144ska","year":"2014","journal-title":"Toxicology"},{"issue":"Suppl. 1","key":"10.1016\/j.yrtph.2018.08.007_bib31","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/S0305-4179(04)90000-9","article-title":"The role of Acticoat with nanocrystalline silver in the management of burns","volume":"30","author":"Dunn","year":"2004","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib32","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/(SICI)1520-6866(1998)18:6<303::AID-TCM4>3.0.CO;2-9","article-title":"Lack of genotoxicity of silver iodide in the SCE assay in vitro, in vivo, and in the Ames\/microsome test","volume":"18","author":"Eliopoulos","year":"1998","journal-title":"Teratog. Carcinog. Mutagen."},{"key":"10.1016\/j.yrtph.2018.08.007_bib33","doi-asserted-by":"crossref","first-page":"8337","DOI":"10.1021\/es1020668","article-title":"p38 MAPK activation, DNA damage, cell cycle arrest and apoptosis as mechanisms of toxicity of silver nanoparticles in Jurkat T cells","volume":"44","author":"Eom","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib34","series-title":"Strength Conversion in Drug Listing","author":"FDA","year":"2017"},{"key":"10.1016\/j.yrtph.2018.08.007_bib35","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s12105-017-0842-x","article-title":"Occupational argyria of the nasal mucosa","volume":"12","author":"Ferrara","year":"2018","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.yrtph.2018.08.007_bib36","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1001\/jama.1984.03340350057031","article-title":"Landmark article June 14, 1941: sulfadiazine. Therapeutic evaluation and toxic effects on four hundred and forty-six patients. By Maxwell Finland, Elias Strauss, and Osler L. Peterson","volume":"251","author":"Finland","year":"1984","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.yrtph.2018.08.007_bib37","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1067\/S0190-9622(02)61574-9","article-title":"Scar-localized argyria secondary to silver sulfadiazine cream","volume":"49","author":"Fisher","year":"2003","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib38","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/j.1365-2133.2008.08690.x","article-title":"Topical silver sulfadiazine-induced systemic argyria in a patient with severe generalized dystrophic epidermolysis bullosa","volume":"159","author":"Flohr","year":"2008","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib39","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1111\/j.1600-0625.2009.00943.x","article-title":"Silver-loaded seaweed-based cellulosic fiber improves epidermal skin physiology in atopic dermatitis: safety assessment, mode of action and controlled, randomized single-blinded exploratory in vivo study","volume":"19","author":"Fluhr","year":"2010","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib40","first-page":"275","article-title":"Silver sulfadiazine for control of burn wound infections","volume":"60","author":"Fox","year":"1975","journal-title":"Int. Surg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib41","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1001\/jama.1979.03290440050030","article-title":"Leukopenia secondary to sulfadiazine silver","volume":"241","author":"Fraser","year":"1979","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.yrtph.2018.08.007_bib42","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/0305-4179(92)90128-H","article-title":"Sensitivity to silver in a patient treated with silver sulphadiazine (Flamazine)","volume":"18","author":"Fraser-Moodie","year":"1992","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib43","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/bjc.1968.12","article-title":"The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesis","volume":"22","author":"Frei","year":"1968","journal-title":"Br. J. Canc."},{"key":"10.1016\/j.yrtph.2018.08.007_bib44","first-page":"51","article-title":"Inactivity of two noble metals as carcinogens","volume":"1","author":"Furst","year":"1978","journal-title":"J. Environ. Pathol. Toxicol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib45","first-page":"115","article-title":"Bone marrow toxicity by silver sulfadiazine","volume":"177","author":"Gamelli","year":"1993","journal-title":"Surg. Gynecol. Obstet."},{"key":"10.1016\/j.yrtph.2018.08.007_bib46","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1111\/bjd.14571","article-title":"In vivo reflectance confocal microscopy characterization of silver deposits in localized cutaneous argyria","volume":"175","author":"Garc\u00eda-Mart\u00ednez","year":"2016","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib47","first-page":"429","article-title":"Incidence of sensitivity to chromium, nickel, gold, silver and copper compared to reactions to their aqueous salts including cobalt sulfate","volume":"12","author":"Gaul","year":"1954","journal-title":"Ann. Allergy"},{"key":"10.1016\/j.yrtph.2018.08.007_bib48","first-page":"83","article-title":"Transient leukopenia associated with topical silver sulfadiazine in burn therapy","volume":"72","author":"Gbaanador","year":"1987","journal-title":"Nebr. Med. J."},{"key":"10.1016\/j.yrtph.2018.08.007_bib49","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1186\/1745-6215-14-403","article-title":"Comparison of three different dressings for partial thickness burns in children: study protocol for a randomised controlled trial","volume":"14","author":"Gee Kee","year":"2013","journal-title":"Trials"},{"key":"10.1016\/j.yrtph.2018.08.007_bib50","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/j.burns.2014.07.024","article-title":"Topical petrolatum gel alone versus topical silver sulfadiazine with standard gauze dressings for the treatment of superficial partial thickness burns in adults: a randomized controlled trial","volume":"40","author":"Genuino","year":"2014","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib51","first-page":"181","article-title":"Human generalized argyria","volume":"108","author":"Gherardi","year":"1984","journal-title":"Arch. Pathol. Lab Med."},{"key":"10.1016\/j.yrtph.2018.08.007_bib52","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.mrgentox.2012.08.007","article-title":"In vitro and in vivo genotoxicity of silver nanoparticles","volume":"749","author":"Ghosh","year":"2012","journal-title":"Mutat. Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib53","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/BF02916928","article-title":"Chromium, selenium, and other trace element intakes of a selected sample of Canadian premenopausal women","volume":"6","author":"Gibson","year":"1984","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib54","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1080\/09553007514550511","article-title":"Effects of x-rays on Ag-DNA complexes","volume":"27","author":"Goff","year":"1975","journal-title":"Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med."},{"key":"10.1016\/j.yrtph.2018.08.007_bib55","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1111\/j.1365-2133.2006.07463.x","article-title":"Penile argyria","volume":"155","author":"Griffiths","year":"2006","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib56","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1080\/17435390.2016.1214764","article-title":"Size- and coating-dependent cytotoxicity and genotoxicity of silver nanoparticles evaluated using in vitro standard assays","volume":"10","author":"Guo","year":"2016","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.yrtph.2018.08.007_bib57","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.toxlet.2010.12.001","article-title":"Silver nanoparticles: evaluation of DNA damage, toxicity and functional impairment in human mesenchymal stem cells","volume":"201","author":"Hackenberg","year":"2011","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.yrtph.2018.08.007_bib58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yrtph.2013.11.002","article-title":"Oral toxicity of silver ions, silver nanoparticles and colloidal silver--a review","volume":"68","author":"Hadrup","year":"2014","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib59","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.neuro.2012.04.008","article-title":"The similar neurotoxic effects of nanoparticulate and ionic silver in vivo and in vitro","volume":"33","author":"Hadrup","year":"2012","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.yrtph.2018.08.007_bib60","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0048-9697(73)90024-7","article-title":"The concentration and distribution of some stable elements in healthy human tissues from the United Kingdom an environmental study","volume":"1","author":"Hamilton","year":"1973","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.yrtph.2018.08.007_bib61","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1097\/ICO.0b013e31818f9724","article-title":"Presumed corneal argyrosis from occlusive soft contact lenses: a case report","volume":"28","author":"Hau","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.yrtph.2018.08.007_bib62","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1600-0536.1979.tb04849.x","article-title":"Contact dermatitis from silver coat","volume":"5","author":"Heyl","year":"1979","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.yrtph.2018.08.007_bib63","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1159\/000093944","article-title":"A new silver-loaded cellulosic fiber with antifungal and antibacterial properties","volume":"33","author":"Hipler","year":"2006","journal-title":"Curr. Probl. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib64","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1001\/archderm.1955.01540300057016","article-title":"Dermatitis caused by metal strands","volume":"71","author":"Hollander","year":"1955","journal-title":"AMA. Arch. Derm."},{"key":"10.1016\/j.yrtph.2018.08.007_bib65","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.jaad.2010.05.016","article-title":"Localized cutaneous argyria","volume":"65","author":"Hristov","year":"2011","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib66","first-page":"F559","article-title":"Vasopressin regulates apical targeting of aquaporin-2 but not of UT1 urea transporter in renal collecting duct","volume":"276","author":"Inoue","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib67","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1600-0536.2007.01253.x","article-title":"Contact sensitivity in patients with venous leg ulcers in Serbia: comparison with contact dermatitis patients and relationship to ulcer duration","volume":"58","author":"Janki\u0107evi\u0107","year":"2008","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.yrtph.2018.08.007_bib68","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/0002-9610(78)90173-3","article-title":"Acute leukopenia during topical burn therapy with silver sulfadiazine","volume":"135","author":"Jarrett","year":"1978","journal-title":"Am. J. Surg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib69","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1046\/j.1365-2133.2003.05188.x","article-title":"Activation of mast cells by silver particles in a patient with localized argyria due to implantation of acupuncture needles","volume":"148","author":"Kakurai","year":"2003","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib70","first-page":"6","article-title":"Localized cutaneous argyria in a silversmith","volume":"23","author":"Kamiya","year":"2011","journal-title":"Eur. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib71","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1046\/j.1365-2133.2001.03977.x","article-title":"Localized argyria in an antique restorer","volume":"144","author":"Kapur","year":"2001","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib72","first-page":"257","article-title":"Corneal argyrosis: histologic, ultrastructural and microanalytic study","volume":"20","author":"Karcioglu","year":"1985","journal-title":"Can. J. Ophthalmol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib73","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/1471-2369-14-96","article-title":"An in vitro assessment of panel of engineered nanomaterials using a human renal cell line: cytotoxicity, pro-inflammatory response, oxidative stress and genotoxicity","volume":"14","author":"Kermanizadeh","year":"2013","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib74","first-page":"835","article-title":"A controlled study of the effects of silver sulfadiazine on white blood cell counts in burned children","volume":"17","author":"Kiker","year":"1977","journal-title":"J. Trauma"},{"key":"10.1016\/j.yrtph.2018.08.007_bib75","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1080\/08958370701874663","article-title":"Twenty-eight-day oral toxicity, genotoxicity, and gender-related tissue distribution of silver nanoparticles in sprague-dawley rats","volume":"20","author":"Kim","year":"2008","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib76","doi-asserted-by":"crossref","first-page":"e2013003","DOI":"10.5620\/eht.2013.28.e2013003","article-title":"Appropriate in vitro methods for genotoxicity testing of silver nanoparticles","volume":"28","author":"Kim","year":"2013","journal-title":"Environ. Health Toxicol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib77","doi-asserted-by":"crossref","first-page":"953","DOI":"10.3109\/17435390.2012.676099","article-title":"Genotoxicity, acute oral and dermal toxicity, eye and dermal irritation and corrosion and skin sensitisation evaluation of silver nanoparticles","volume":"7","author":"Kim","year":"2013","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.yrtph.2018.08.007_bib78","first-page":"133","article-title":"The use of BAL in generalized argyria","volume":"70","author":"Kleckner","year":"1949","journal-title":"Calif. Med."},{"key":"10.1016\/j.yrtph.2018.08.007_bib79","first-page":"1","article-title":"Assessment of dermal exposure and histopathologic changes of different sized nano-silver in healthy adult rabbits","volume":"304","author":"Koohi","year":"2011","journal-title":"J. ofPhysicsConference Ser."},{"key":"10.1016\/j.yrtph.2018.08.007_bib80","first-page":"511","article-title":"Sub-chronic dermal toxicity of silver nanoparticles in Guinea pig: special emphasis to heart, bone and kidney toxicities. Iran","volume":"12","author":"Korani","year":"2013","journal-title":"J. Pharm. Res. IJPR"},{"key":"10.1016\/j.yrtph.2018.08.007_bib81","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.toxlet.2013.03.006","article-title":"Oxidative DNA damage corresponds to the long term survival of human cells treated with silver nanoparticles","volume":"219","author":"Kruszewski","year":"2013","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.yrtph.2018.08.007_bib82","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1600-0536.1997.tb00396.x","article-title":"Contact allergy to dental restorative materials in patients with oral lichenoid lesions","volume":"36","author":"Laine","year":"1997","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.yrtph.2018.08.007_bib83","first-page":"151","volume":"18","author":"Lancaster","year":"1920","journal-title":"Argyrol. Trans. Am. Ophthalmol. Soc."},{"key":"10.1016\/j.yrtph.2018.08.007_bib84","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.mrrev.2008.10.002","article-title":"Genotoxicity investigations on nanomaterials: methods, preparation and characterization of test material, potential artifacts and limitations--many questions, some answers","volume":"681","author":"Landsiedel","year":"2009","journal-title":"Mutat. Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib85","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000093928","article-title":"Silver in health care: antimicrobial effects and safety in use","volume":"33","author":"Lansdown","year":"2006","journal-title":"Curr. Probl. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib86","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0305-4179(74)90009-6","article-title":"Distribution and excretion of silver sulphadiazine applied to scalds in the pig","volume":"1","author":"Lazare","year":"1974","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib87","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1346-8138.1994.tb01410.x","article-title":"Generalized argyria after habitual use of AgNO3","volume":"21","author":"Lee","year":"1994","journal-title":"J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib88","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.mrgentox.2011.11.010","article-title":"Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay","volume":"745","author":"Li","year":"2012","journal-title":"Mutat. Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib89","article-title":"Differential genotoxicity mechanisms of silver nanoparticles and silver ions","author":"Li","year":"2016","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib90","doi-asserted-by":"crossref","first-page":"6903","DOI":"10.1021\/nn102272n","article-title":"Controlled release of biologically active silver from nanosilver surfaces","volume":"4","author":"Liu","year":"2010","journal-title":"ACS Nano"},{"key":"10.1016\/j.yrtph.2018.08.007_bib91","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0305-4179(83)90121-3","article-title":"Topical silver sulphadiazine: side effects and urinary excretion","volume":"10","author":"Lockhart","year":"1983","journal-title":"Burns. Incl. Therm. Inj."},{"key":"10.1016\/j.yrtph.2018.08.007_bib92","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/BF02160348","article-title":"Argyrosis of the lacrimal sac","volume":"225","author":"Loeffler","year":"1987","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol. = Albr. von Graefes Arch. f\u00fcr Klin. und Exp. Ophthalmol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib93","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1021\/ja00838a047","article-title":"Letter: studies of heavy metal binding with polynucleotides using optical detection of magnetic resonance. Silver(I) binding","volume":"97","author":"Luk","year":"1975","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.yrtph.2018.08.007_bib94","first-page":"217","article-title":"[Increased serum and urinary levels of silver during treatment with topical silver sulfadiazine]","volume":"129","author":"Maitre","year":"2002","journal-title":"Ann. dermatologie v\u00e9n\u00e9r\u00e9ologie"},{"key":"10.1016\/j.yrtph.2018.08.007_bib95","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1292\/jvms.11-0038","article-title":"An evaluation of acute toxicity of colloidal silver nanoparticles","volume":"73","author":"Maneewattanapinyo","year":"2011","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.yrtph.2018.08.007_bib96","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1136\/bmj.2.2381.359","article-title":"The bactericidal action of compounds of silver","volume":"2","author":"Marshall","year":"1906","journal-title":"Br. Med. J."},{"key":"10.1016\/j.yrtph.2018.08.007_bib97","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1001\/archderm.1977.01640080079013","article-title":"Systemic argyria secondary to topical silver nitrate","volume":"113","author":"Marshall","year":"1977","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib98","first-page":"390","article-title":"Fatal acute agranulocytosis following prolonged administration of small doses of sulfadiazine for urinary bacteriostasis","volume":"72","author":"Marshall","year":"1950","journal-title":"Calif. Med."},{"key":"10.1016\/j.yrtph.2018.08.007_bib99","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3109\/01913129809032257","article-title":"Human generalized argyria: a submicroscopic and X-ray spectroscopic study","volume":"22","author":"Massi","year":"1998","journal-title":"Ultrastruct. Pathol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib100","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1346-8138.1992.tb03186.x","article-title":"Detection of selenium in generalized and localized argyria: report of four cases with X-ray microanalysis","volume":"19","author":"Matsumura","year":"1992","journal-title":"J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib101","article-title":"A case of argyria and acute leukopenia associated with the use of an antimicrobial soft silicone foam dressing","author":"McCague","year":"2015","journal-title":"J. Burn Care Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib102","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/0305-4179(94)00023-Q","article-title":"Serious silver sulphadiazine and mafenide acetate dermatitis","volume":"21","author":"McKenna","year":"1995","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib103","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/00000441-195110000-00004","article-title":"Successful use of acth in the treatment of agranulocytosis due to sulfadiazine","volume":"222","author":"McMillin","year":"1951","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.yrtph.2018.08.007_bib104","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/em.21698","article-title":"Silver nanoparticle-induced mutations and oxidative stress in mouse lymphoma cells","volume":"53","author":"Mei","year":"2012","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.yrtph.2018.08.007_bib105","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1524-475X.2010.00603.x","article-title":"A randomized-controlled trial comparing cadexomer iodine and nanocrystalline silver on the healing of leg ulcers","volume":"18","author":"Miller","year":"2010","journal-title":"Wound Repair Regen."},{"key":"10.1016\/j.yrtph.2018.08.007_bib106","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.burns.2010.09.006","article-title":"Acticoat dressings and major burns: systemic silver absorption","volume":"37","author":"Moiemen","year":"2011","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib107","first-page":"93","article-title":"Preventing ophthalmia neonatorum. Paediatr","volume":"20","author":"Moore","year":"2015","journal-title":"Child Health"},{"key":"10.1016\/j.yrtph.2018.08.007_bib108","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/j.1365-2133.1996.tb01522.x","article-title":"Localized argyria caused by silver earrings","volume":"135","author":"Morton","year":"1996","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib109","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1001\/archsurg.1965.01320120014002","article-title":"Treatment of large human burns with 0.5 per cent silver nitrate solution","volume":"90","author":"Moyer","year":"1965","journal-title":"Arch. Surg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib110","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1524-475X.2010.00579.x","article-title":"Does nanocrystalline silver have a transferable effect?","volume":"18","author":"Nadworny","year":"2010","journal-title":"Wound Repair Regen."},{"key":"10.1016\/j.yrtph.2018.08.007_bib111","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1111\/1346-8138.13387","article-title":"Single, blue nevus-like localized argyria","volume":"43","author":"Nagano","year":"2016","journal-title":"J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib112","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1467-2494.2006.00322.x","article-title":"New antiaxillary odour deodorant made with antimicrobial Ag-zeolite (silver-exchanged zeolite)","volume":"28","author":"Nakane","year":"2006","journal-title":"Int. J. Cosmet. Sci."},{"key":"10.1016\/j.yrtph.2018.08.007_bib113","first-page":"549","article-title":"Ber die Nichtexistenz von\u202f?Metallkrebs? im Falle der Edelmetalle","volume":"45","author":"Nothdurft","year":"1958","journal-title":"Naturwissenschaften"},{"key":"10.1016\/j.yrtph.2018.08.007_bib114","first-page":"439","article-title":"Carcinogenic effect of metals in rodents","volume":"16","author":"Oppenheimer","year":"1956","journal-title":"Can. Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib115","doi-asserted-by":"crossref","first-page":"99","DOI":"10.32607\/20758251-2009-1-3-99-101","article-title":"Genotoxic effects of silver nanoparticles on mice in vivo","volume":"1","author":"Ordzhonikidze","year":"2009","journal-title":"Acta Naturae"},{"key":"10.1016\/j.yrtph.2018.08.007_bib116","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1001\/archinte.1974.00320200142021","article-title":"Nephrotic syndrome following topically applied sulfadiazine silver therapy","volume":"134","author":"Owens","year":"1974","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.yrtph.2018.08.007_bib117","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1600-0536.2009.01566.x","article-title":"A rare case of allergic contact dermatitis from silver nitrate in a widely used special patch test marker","volume":"61","author":"Ozkaya","year":"2009","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.yrtph.2018.08.007_bib118","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1001\/archophthalmol.2010.37","article-title":"Black tears (melanodacryorrhea) from argyrosis","volume":"128","author":"Palamar","year":"2010","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib119","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1001\/archderm.1978.01640150009003","article-title":"Generalized argyria. Clinicopathologic features and histochemical studies","volume":"114","author":"Pariser","year":"1978","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib120","doi-asserted-by":"crossref","first-page":"9810","DOI":"10.1016\/j.biomaterials.2011.08.085","article-title":"The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles","volume":"32","author":"Park","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.yrtph.2018.08.007_bib121","doi-asserted-by":"crossref","first-page":"e62","DOI":"10.1111\/jdv.14526","article-title":"Localized argyria: troublesome side-effect of acupuncture","volume":"32","author":"Park","year":"2018","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib122","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/0140-6736(92)90458-F","article-title":"Argyria from excessive use of topical silver sulphadiazine","volume":"340","author":"Payne","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.yrtph.2018.08.007_bib123","series-title":"SILVADENE- Silver Sulfadiazine Cream","author":"Pfizer","year":"2016"},{"key":"10.1016\/j.yrtph.2018.08.007_bib124","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1111\/wrr.12209","article-title":"Transdermal uptake and organ distribution of silver from two different wound dressings in rats after a burn trauma","volume":"22","author":"Pfurtscheller","year":"2014","journal-title":"Wound Repair Regen."},{"key":"10.1016\/j.yrtph.2018.08.007_bib125","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1097\/00000658-196610000-00018","article-title":"Treatment of severe burns with aqueous silver nitrate (0.5 percent)","volume":"164","author":"Polk","year":"1966","journal-title":"Ann. Surg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib126","series-title":"Pubmed","author":"Pubmed","year":"2018"},{"key":"10.1016\/j.yrtph.2018.08.007_bib127","first-page":"69","article-title":"[Acute fatal poisoning with silver nitrate following an abortion attempt]","volume":"148","author":"Reinhardt","year":"1971","journal-title":"Arch. f\u00fcr Kriminologie"},{"key":"10.1016\/j.yrtph.2018.08.007_bib128","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/0002-9149(72)90075-6","article-title":"Argyria presenting as cyanotic heart-disease","volume":"30","author":"Rich","year":"1972","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib129","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1067\/mjd.2002.116227","article-title":"Localized argyria with pseudo-ochronosis","volume":"46","author":"Robinson-Bostom","year":"2002","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib130","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/S0190-9622(08)80271-X","article-title":"Blue nevi-like dotted occupational argyria","volume":"27","author":"Rongioletti","year":"1992","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib131","first-page":"509","article-title":"Argyria: report of a case associated with abnormal electroencephalographic and brain scan findings","volume":"87","author":"Rosenblatt","year":"1987","journal-title":"J. Am. Osteopath. Assoc."},{"key":"10.1016\/j.yrtph.2018.08.007_bib132","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0014-4835(86)90021-7","article-title":"The silver nitrate prophylaxis of Cred\u00e9 causes silver deposition in the cornea of experimental animals","volume":"42","author":"Rungby","year":"1986","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.yrtph.2018.08.007_bib133","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0048-9697(77)90005-5","article-title":"Metallobiochemistry of heavy metal pollution: nuclear and radiochemical techniques for long term--low level exposure (LLE) experiments","volume":"7","author":"Sabbioni","year":"1977","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.yrtph.2018.08.007_bib134","article-title":"Studies on promoting action in skin carcinogenesis","volume":"10","author":"Saffiotti","year":"1963","journal-title":"Natl. Canc. Inst. Monogr."},{"key":"10.1016\/j.yrtph.2018.08.007_bib135","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1289\/ehp.0901398","article-title":"Evaluation of silver nanoparticle toxicity in skin in vivo and keratinocytes in vitro","volume":"118","author":"Samberg","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.yrtph.2018.08.007_bib136","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/0305-4179(82)90010-9","article-title":"Absorption, excretion and tissue distribution of silver sulphadiazine","volume":"8","author":"Sano","year":"1982","journal-title":"Burns. Incl. Therm. Inj."},{"key":"10.1016\/j.yrtph.2018.08.007_bib137","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1046\/j.1365-2133.1999.02628.x","article-title":"Two unusual cases of argyria: the application of an improved tissue processing method for X-ray microanalysis of selenium and sulphur in silver-laden granules","volume":"140","author":"Sato","year":"1999","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib138","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/00003226-200107000-00026","article-title":"Multifocal corneal argyrosis after an explosion injury","volume":"20","author":"Schl\u00f6tzer-Schrehardt","year":"2001","journal-title":"Cornea"},{"key":"10.1016\/j.yrtph.2018.08.007_bib139","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1007\/BF00525126","article-title":"Versuche zur Krebserzeugung mit kolloidalen Silber und Goldl\u00f5sungen an Ratten","volume":"63","author":"Schm\u00e3hl","year":"1960","journal-title":"Z. Krebsforsch."},{"key":"10.1016\/j.yrtph.2018.08.007_bib140","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1002\/jps.23108","article-title":"Transdermal delivery using a novel electrochemical device, part 2: in vivo study in humans","volume":"101","author":"Schr\u00f6der","year":"2012","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.yrtph.2018.08.007_bib141","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/j.1365-2133.1990.tb06302.x","article-title":"An unusual case of acquired localized argyria","volume":"123","author":"Shall","year":"1990","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib142","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1001\/jamadermatol.2013.8044","article-title":"Dystrophic calcification and accentuated localized argyria after fractionated carbon dioxide laser therapy of hypertrophic scars","volume":"150","author":"Shaub","year":"2014","journal-title":"JAMA Dermatology"},{"key":"10.1016\/j.yrtph.2018.08.007_bib143","series-title":"FLAMAZINE Cream 1 % W\/w","author":"Smith_&_Nephew_Healthcare_Ltd","year":"2011"},{"key":"10.1016\/j.yrtph.2018.08.007_bib144","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.mrgentox.2015.11.002","article-title":"Cytotoxicity and genotoxicity of silver nanoparticles of different sizes in CHO-K1 and CHO-XRS5 cell lines","volume":"795","author":"Souza","year":"2016","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen"},{"key":"10.1016\/j.yrtph.2018.08.007_bib145","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1179\/2049396714Y.0000000070","article-title":"Dermal exposure potential from textiles that contain silver nanoparticles","volume":"20","author":"Stefaniak","year":"2014","journal-title":"Int. J. Occup. Environ. Health"},{"key":"10.1016\/j.yrtph.2018.08.007_bib146","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1056\/NEJM196907312810509","article-title":"Successful treatment of methemoglobinemia secondary to silver nitrate therapy","volume":"281","author":"Strauch","year":"1969","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.yrtph.2018.08.007_bib147","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0001-2092(08)70671-9","article-title":"Methemoglobinemia: a complication of silver nitrite therapy used in burns","volume":"10","author":"Strauch","year":"1969","journal-title":"AORN J."},{"key":"10.1016\/j.yrtph.2018.08.007_bib148","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1054\/bjps.2000.3543","article-title":"Argyria caused by an earring","volume":"54","author":"Sugden","year":"2001","journal-title":"Br. J. Plast. Surg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib149","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/0190-9622(93)70249-S","article-title":"Localized argyria with chrysiasis caused by implanted acupuncture needles. Distribution and chemical forms of silver and gold in cutaneous tissue by electron microscopy and x-ray microanalysis","volume":"29","author":"Suzuki","year":"1993","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib150","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1001\/archderm.1985.01660120076024","article-title":"Blue macules of localized argyria caused by implanted acupuncture needles. Electron microscopy and roentgenographic microanalysis of deposited metal","volume":"121","author":"Tanita","year":"1985","journal-title":"Arch. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib151","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1097\/ICO.0000000000001191","article-title":"Ocular argyrosis mimicking conjunctival melanoma","volume":"36","author":"Tendler","year":"2017","journal-title":"Cornea"},{"key":"10.1016\/j.yrtph.2018.08.007_bib152","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/00004630-198909000-00008","article-title":"Leukopenia in acute thermal injury: evidence against topical silver sulfadiazine as the causative agent","volume":"10","author":"Thomson","year":"1989","journal-title":"J. Burn Care Rehabil."},{"key":"10.1016\/j.yrtph.2018.08.007_bib153","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0140-6736(04)15540-2","article-title":"A silver man","volume":"363","author":"Tomi","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.yrtph.2018.08.007_bib154","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1365-2885.2004.00576.x","article-title":"Idiosyncratic toxicity associated with potentiated sulfonamides in the dog","volume":"27","author":"Trepanier","year":"2004","journal-title":"J. Vet. Pharmacol. Therapeut."},{"key":"10.1016\/j.yrtph.2018.08.007_bib155","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1097\/01.ta.0000208126.22089.b6","article-title":"Silver-coated dressing acticoat caused raised liver enzymes and argyria-like symptoms in burn patient","volume":"60","author":"Trop","year":"2006","journal-title":"J. Trauma"},{"key":"10.1016\/j.yrtph.2018.08.007_bib156","doi-asserted-by":"crossref","first-page":"S92","DOI":"10.1016\/j.jaad.2005.10.062","article-title":"Local cutaneous argyria mimicking melanoma metastases in a patient with disseminated melanoma","volume":"55","author":"Utikal","year":"2006","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib157","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/00005373-197802000-00016","article-title":"Acute leukopenia associated with silver sulfadiazine therapy","volume":"18","author":"Valente","year":"1978","journal-title":"J. Trauma"},{"key":"10.1016\/j.yrtph.2018.08.007_bib158","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1179\/acb.2005.008","article-title":"Long-term use of silver containing nose-drops resulting in systemic argyria","volume":"60","author":"Van de Voorde","year":"2005","journal-title":"Acta Clin. Belg."},{"key":"10.1016\/j.yrtph.2018.08.007_bib159","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1159\/000248542","article-title":"Localized argyria caused by silver earrings","volume":"177","author":"van den Nieuwenhuijsen","year":"1988","journal-title":"Dermatology"},{"key":"10.1016\/j.yrtph.2018.08.007_bib160","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/S0929-693X(97)88977-4","article-title":"[Agranulocytosis after application of silver sulfadiazine in a 2-month old infant]","volume":"4","author":"Viala","year":"1997","journal-title":"Arch. p\u00e9diatrie organe Off. la Soci\u00e9te Fr. p\u00e9diatrie"},{"key":"10.1016\/j.yrtph.2018.08.007_bib161","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.burns.2007.07.014","article-title":"The safety of nanocrystalline silver dressings on burns: a study of systemic silver absorption","volume":"33","author":"Vlachou","year":"2007","journal-title":"Burns"},{"key":"10.1016\/j.yrtph.2018.08.007_bib162","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1080\/00039896.1965.10664198","article-title":"Percutaneous toxicity of metal compounds. A comparative investigation in Guinea pigs","volume":"11","author":"Wahlberg","year":"1965","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.yrtph.2018.08.007_bib163","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1093\/clinchem\/37.10.1683","article-title":"Determination of silver in blood, urine, and tissues of volunteers and burn patients","volume":"37","author":"Wan","year":"1991","journal-title":"Clin. Chem."},{"key":"10.1016\/j.yrtph.2018.08.007_bib164","series-title":"Guidelines ForDrinking-water Quality","author":"WHO, (WHO), W.H.O","year":"2008"},{"key":"10.1016\/j.yrtph.2018.08.007_bib165","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0305-4179(86)90136-1","article-title":"Topical silver sulphadiazine and profound neutropenia in a burned child","volume":"12","author":"Wilson","year":"1986","journal-title":"Burns. Incl. Therm. Inj."},{"key":"10.1016\/j.yrtph.2018.08.007_bib166","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000093926","article-title":"Skin physiology and textiles - consideration of basic interactions","volume":"33","author":"Wollina","year":"2006","journal-title":"Curr. Probl. Dermatol."},{"key":"10.1016\/j.yrtph.2018.08.007_bib167","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijpharm.2011.10.042","article-title":"In vitro and in vivo transdermal iontophoretic delivery of naloxone, an opioid antagonist","volume":"422","author":"Yamamoto","year":"2012","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.yrtph.2018.08.007_bib168","doi-asserted-by":"crossref","first-page":"722","DOI":"10.12968\/jowc.2016.25.12.722","article-title":"Outcomes of acute dermal irritation and sensitisation tests on active dressings for chronic wounds: a comparative study","volume":"25","author":"Zelga","year":"2016","journal-title":"J. Wound Care"},{"key":"10.1016\/j.yrtph.2018.08.007_bib169","first-page":"197","article-title":"Semi-permanent skin staining associated with silver-coated wound dressing Acticoat","volume":"27","author":"Zweiker","year":"2014","journal-title":"Ann. Burns Fire Disasters"}],"container-title":["Regulatory Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0273230018302174?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0273230018302174?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T05:57:57Z","timestamp":1720504677000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0273230018302174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":169,"alternative-id":["S0273230018302174"],"URL":"https:\/\/doi.org\/10.1016\/j.yrtph.2018.08.007","relation":{},"ISSN":["0273-2300"],"issn-type":[{"value":"0273-2300","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review","name":"articletitle","label":"Article Title"},{"value":"Regulatory Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yrtph.2018.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}