{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:51:38Z","timestamp":1792439498092,"version":"4.5.0"},"reference-count":129,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:00:00Z","timestamp":1791417600000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008672","name":"Wilhelm Sander Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008672","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Zeitschrift f\u00fcr Medizinische Physik"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.zemedi.2026.09.004","type":"journal-article","created":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T11:15:01Z","timestamp":1792322101000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Review on carbon ion minibeam radiotherapy: Dosimetry, dynamic phantoms and radiobiology"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0273-0878","authenticated-orcid":false,"given":"Christina","family":"Stengl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5510-9749","authenticated-orcid":false,"given":"Jos\u00e9","family":"Vedelago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6056-9747","authenticated-orcid":false,"given":"Oliver","family":"J\u00e4kel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3857\/roj.2018.00122","article-title":"Intensity-modulated radiation therapy: a review with a physics perspective","volume":"36","author":"Cho","year":"2018","journal-title":"Radiat Oncol J"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1102\/1470-7330.2004.0003","article-title":"Intensity-modulated radiotherapy - what is it?","volume":"4","author":"Taylor","year":"2004","journal-title":"Cancer Imaging"},{"issue":"12","key":"10.1016\/j.zemedi.2026.09.004_b3","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/nrclinonc.2012.194","article-title":"Image-guided radiotherapy: from current concept to future perspectives","volume":"9","author":"Jaffray","year":"2012","journal-title":"Nat Rev Clin Oncol"},{"issue":"5","key":"10.1016\/j.zemedi.2026.09.004_b4","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.clon.2015.01.007","article-title":"New developments in intracranial stereotactic radiotherapy for metastases","volume":"27","author":"Pinkham","year":"2015","journal-title":"Clin Oncol"},{"issue":"3","key":"10.1016\/j.zemedi.2026.09.004_b5","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1053\/j.seminoncol.2019.07.005","article-title":"Clinical applications of proton and carbon ion therapy","volume":"46","author":"Rackwitz","year":"2019","journal-title":"Semin Oncol"},{"key":"10.1016\/j.zemedi.2026.09.004_b6","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3389\/fonc.2020.00082","article-title":"Carbon ion therapy: A modern review of an emerging technology","volume":"10","author":"Malouff","year":"2020","journal-title":"Front Oncol"},{"issue":"15","key":"10.1016\/j.zemedi.2026.09.004_b7","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.3390\/cancers14153625","article-title":"Should peak dose be used to prescribe spatially fractionated radiation therapy?\u2014A review of preclinical studies","volume":"14","author":"Fernandez-Palomo","year":"2022","journal-title":"Cancers"},{"issue":"8","key":"10.1016\/j.zemedi.2026.09.004_b8","doi-asserted-by":"crossref","first-page":"5551","DOI":"10.1002\/mp.15780","article-title":"Preclinical dosimetry in proton minibeam radiation therapy: Robustness analysis and guidelines","volume":"49","author":"Ortiz","year":"2022","journal-title":"Med Phys"},{"issue":"11","key":"10.1016\/j.zemedi.2026.09.004_b9","doi-asserted-by":"crossref","first-page":"4897","DOI":"10.1118\/1.3232000","article-title":"X-ray energy optimization in minibeam radiation therapy","volume":"36","author":"Prezado","year":"2009","journal-title":"Med Phys"},{"issue":"8","key":"10.1016\/j.zemedi.2026.09.004_b10","doi-asserted-by":"crossref","first-page":"5222","DOI":"10.1002\/mp.16432","article-title":"Development and characterization of a versatile mini-beam collimator for pre-clinical photon beam irradiation","volume":"50","author":"Stengl","year":"2023","journal-title":"Med Phys"},{"key":"10.1016\/j.zemedi.2026.09.004_b11","article-title":"Mini review of spatially fractionated radiation therapy for cancer management","volume":"9","author":"Mali","year":"2024","journal-title":"Oral Oncol Rep"},{"issue":"11","key":"10.1016\/j.zemedi.2026.09.004_b12","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1158\/2326-6066.CIR-24-0902","article-title":"Evaluation of proton minibeam radiotherapy on antitumor immune responses in a rat model of glioblastoma","volume":"13","author":"Iturri","year":"2025","journal-title":"Cancer Immunol Res"},{"key":"10.1016\/j.zemedi.2026.09.004_b13","article-title":"Proton minibeam radiotherapy: a review","volume":"15","author":"Yang","year":"2025","journal-title":"Front Oncol"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b14","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.ijrobp.2024.04.011","article-title":"Thoracic proton minibeam radiation therapy: Tissue preservation and survival advantage over conventional proton therapy","volume":"120","author":"Bertho","year":"2024","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b15","article-title":"A carbon minibeam irradiation facility concept","volume":"2420","author":"Mayerhofer","year":"2023","journal-title":"J Phys: Conf Ser"},{"key":"10.1016\/j.zemedi.2026.09.004_b16","article-title":"Dose assessment in moving targets and organs at risk during carbon ion therapy for pancreatic cancer with respiratory gating","volume":"34","author":"Stengl","year":"2025","journal-title":"Phys Imaging Radiat Oncol"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b17","doi-asserted-by":"crossref","first-page":"7305","DOI":"10.1038\/s41598-025-91872-6","article-title":"Carbon minibeam radiation therapy results in tumor growth delay in an osteosarcoma murine model","volume":"15","author":"Bertho","year":"2025","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000323476","article-title":"Preface","volume":"11","author":"Kudo","year":"2011","journal-title":"Pancreatology"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12957-021-02478-x","article-title":"Prognosis and survival analysis of patients with pancreatic cancer: retrospective experience of a single institution","volume":"20","author":"Li","year":"2022","journal-title":"World J Surg Oncol"},{"issue":"10485","key":"10.1016\/j.zemedi.2026.09.004_b20","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1016\/S0140-6736(25)00261-2","article-title":"Pancreatic cancer","volume":"405","author":"Stoop","year":"2025","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.zemedi.2026.09.004_b21","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/j.hpb.2022.02.013","article-title":"Quality of life after pancreatic surgery \u2013 A systematic review","volume":"24","author":"James","year":"2022","journal-title":"HPB"},{"issue":"9","key":"10.1016\/j.zemedi.2026.09.004_b22","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.3390\/cancers15092584","article-title":"Current approaches for the curative-intent surgical treatment of pancreatic ductal adenocarcinoma","volume":"15","author":"S\u0142 odkowski","year":"2023","journal-title":"Cancers"},{"issue":"11","key":"10.1016\/j.zemedi.2026.09.004_b23","doi-asserted-by":"crossref","first-page":"2789","DOI":"10.3390\/cancers14112789","article-title":"Proton therapy in the management of pancreatic cancer","volume":"14","author":"Kobeissi","year":"2022","journal-title":"Cancers"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b24","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ijrobp.2024.12.020","article-title":"Proton beam therapy for pancreatic tumors: A consensus statement from the particle therapy cooperative group gastrointestinal subcommittee","volume":"122","author":"Chhabra","year":"2025","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"issue":"10","key":"10.1016\/j.zemedi.2026.09.004_b25","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.3390\/cancers15102857","article-title":"Carbon-ion radiotherapy combined with concurrent chemotherapy for locally advanced pancreatic cancer: A retrospective case series analysis","volume":"15","author":"Okamoto","year":"2023","journal-title":"Cancers"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b26","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/adb89b","article-title":"Evaluation of motion mitigation strategies for carbon ion therapy of abdominal tumors based on non-periodic imaging data","volume":"70","author":"Steinsberger","year":"2025","journal-title":"Phys Med Biol"},{"issue":"24","key":"10.1016\/j.zemedi.2026.09.004_b27","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/ad0902","article-title":"A phantom to simulate organ motion and its effect on dose distribution in carbon ion therapy for pancreatic cancer","volume":"68","author":"Stengl","year":"2023","journal-title":"Phys Med Biol"},{"issue":"8","key":"10.1016\/j.zemedi.2026.09.004_b28","doi-asserted-by":"crossref","first-page":"5618","DOI":"10.1002\/mp.17077","article-title":"Dosimetric study for breathing-induced motion effects in an abdominal pancreas phantom for carbon ion mini-beam radiotherapy","volume":"51","author":"Stengl","year":"2024","journal-title":"Med Phys"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b29","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3390\/cancers9060066","article-title":"Carbon ion radiotherapy: A review of clinical experiences and preclinical research, with an emphasis on DNA damage\/repair","volume":"9","author":"Mohamad","year":"2017","journal-title":"Cancers"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b30","doi-asserted-by":"crossref","first-page":"01TR02","DOI":"10.1088\/1361-6560\/aa9102","article-title":"RBE and related modeling in carbon-ion therapy","volume":"63","author":"Karger","year":"2017","journal-title":"Phys Med Biol"},{"issue":"suppl_1","key":"10.1016\/j.zemedi.2026.09.004_b31","doi-asserted-by":"crossref","first-page":"i58","DOI":"10.1093\/jrr\/rry014","article-title":"Selection of carbon beam therapy: biophysical models of carbon beam therapy","volume":"59","author":"Matsufuji","year":"2018","journal-title":"J Radiat Res"},{"key":"10.1016\/j.zemedi.2026.09.004_b32","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.1016\/S0167-8140(04)80041-0","article-title":"RBE of carbon ions: Experimental data and the strategy of RBE calculation for treatment planning","volume":"73","author":"Weyrather","year":"2004","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.zemedi.2026.09.004_b33","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.788293","article-title":"Biological effects of monoenergetic carbon ions and their associated secondary particles","volume":"12","author":"Buglewicz","year":"2022","journal-title":"Front Oncol"},{"issue":"7","key":"10.1016\/j.zemedi.2026.09.004_b34","doi-asserted-by":"crossref","DOI":"10.1088\/1367-2630\/10\/7\/075009","article-title":"Clinical advantages of carbon-ion radiotherapy","volume":"10","author":"Tsujii","year":"2008","journal-title":"New J Phys"},{"key":"10.1016\/j.zemedi.2026.09.004_b35","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.radonc.2018.12.028","article-title":"DNA damage response of clinical carbon ion versus photon radiation in human glioblastoma cells","volume":"133","author":"Lopez Perez","year":"2019","journal-title":"Radiother Oncol"},{"issue":"18","key":"10.1016\/j.zemedi.2026.09.004_b36","doi-asserted-by":"crossref","first-page":"6602","DOI":"10.3390\/ijms21186602","article-title":"Comparison of high- and low-LET radiation-induced DNA double-strand break processing in living cells","volume":"21","author":"Roobol","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b37","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2022.2057892","article-title":"Carbon ion radiotherapy triggers immunogenic cell death and sensitizes melanoma to anti-PD-1 therapy in mice","volume":"11","author":"Zhou","year":"2022","journal-title":"OncoImmunology"},{"issue":"18","key":"10.1016\/j.zemedi.2026.09.004_b38","doi-asserted-by":"crossref","first-page":"4494","DOI":"10.3390\/cancers15184494","article-title":"Carbon ions for hypoxic tumors: Are we making the most of them?","volume":"15","author":"Sokol","year":"2023","journal-title":"Cancers"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b39","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.radonc.2010.01.015","article-title":"Proton vs carbon ion beams in the definitive radiation treatment of cancer patients","volume":"95","author":"Suit","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.zemedi.2026.09.004_b40","article-title":"Clinical white paper from the \u201cHadrontherapy for Life\u201d symposium\u2013Clinical expansion of carbon ion facilities worldwide","volume":"19","author":"Thariat","year":"2026","journal-title":"Int J Part Ther"},{"key":"10.1016\/j.zemedi.2026.09.004_b41","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.radonc.2020.05.012","article-title":"Carbon ion radiotherapy in pancreatic cancer: A review of clinical data","volume":"147","author":"Liermann","year":"2020","journal-title":"Radiother Oncol"},{"issue":"4","key":"10.1016\/j.zemedi.2026.09.004_b42","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1007\/s00066-021-01827-9","article-title":"Carbon ion radiotherapy as definitive treatment in locally recurrent pancreatic cancer","volume":"198","author":"Liermann","year":"2022","journal-title":"Strahlenther Und Onkol"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b43","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/cncr.27723","article-title":"Phase 1 trial of preoperative, short-course carbon-ion radiotherapy for patients with resectable pancreatic cancer","volume":"119","author":"Shinoto","year":"2013","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b44","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.ijrobp.2015.12.362","article-title":"Carbon ion radiation therapy with concurrent gemcitabine for patients with locally advanced pancreatic cancer","volume":"95","author":"Shinoto","year":"2016","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"issue":"5","key":"10.1016\/j.zemedi.2026.09.004_b45","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.ijrobp.2018.04.057","article-title":"Multi-institutional study of carbon-ion radiotherapy for locally advanced pancreatic cancer: Japan carbon-ion radiation oncology study group (j-CROS) study 1403 pancreas","volume":"101","author":"Kawashiro","year":"2018","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"key":"10.1016\/j.zemedi.2026.09.004_b46","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ejmp.2022.06.010","article-title":"Technical aspects of proton minibeam radiation therapy: Minibeam generation and delivery","volume":"100","author":"Schneider","year":"2022","journal-title":"Phys Medica"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b47","doi-asserted-by":"crossref","first-page":"14403","DOI":"10.1038\/s41598-017-14786-y","article-title":"Proton minibeam radiation therapy spares normal rat brain: Long-term clinical, radiological and histopathological analysis","volume":"7","author":"Prezado","year":"2017","journal-title":"Sci Rep"},{"issue":"23","key":"10.1016\/j.zemedi.2026.09.004_b48","doi-asserted-by":"crossref","first-page":"8924","DOI":"10.1088\/1361-6560\/aa926b","article-title":"Minibeam radiotherapy with small animal irradiators; in vitro and in vivo feasibility studies","volume":"62","author":"Bazyar","year":"2017","journal-title":"Phys Med Biol"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b49","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.ijrobp.2020.09.039","article-title":"Establishment of microbeam radiation therapy at a small-animal irradiator","volume":"109","author":"Treibel","year":"2021","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"key":"10.1016\/j.zemedi.2026.09.004_b50","article-title":"Novel unconventional radiotherapy techniques: Current status and future perspectives \u2013 Report from the 2nd international radiation oncology online seminar","volume":"40","author":"Tubin","year":"2023","journal-title":"Clin Transl Radiat Oncol"},{"issue":"11","key":"10.1016\/j.zemedi.2026.09.004_b51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0224873","article-title":"Proton pencil minibeam irradiation of an in-vivo mouse ear model spares healthy tissue dependent on beam size","volume":"14","author":"Sammer","year":"2019","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b52","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1215\/15228517-4-1-26","article-title":"Response of rat intracranial 9L gliosarcoma to microbeam radiation therapy","volume":"4","author":"Dilmanian","year":"2002","journal-title":"Neuro-Oncol"},{"issue":"3","key":"10.1016\/j.zemedi.2026.09.004_b53","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1002\/mp.12749","article-title":"Quantitative evaluation of potential irradiation geometries for carbon-ion beam grid therapy","volume":"45","author":"Tsubouchi","year":"2018","journal-title":"Med Phys"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b54","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/153303460200100207","article-title":"The impact of TNF-\u03b1 induction on therapeutic efficacy following high dose spatially fractionated (GRID) radiation","volume":"1","author":"Sathishkumar","year":"2002","journal-title":"Technol Cancer Res Treat"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b55","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.ijrobp.2022.08.011","article-title":"Evaluation of the role of the immune system response after minibeam radiation therapy","volume":"115","author":"Bertho","year":"2023","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b56","doi-asserted-by":"crossref","first-page":"8210","DOI":"10.1038\/s41598-025-87395-9","article-title":"Spatially fractionated minibeam radiation delivered at clinically feasible dose rates induces transient vascular permeability","volume":"15","author":"Fazzari","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.zemedi.2026.09.004_b57","first-page":"44","article-title":"X-rays minibeam radiation therapy at a conventional irradiator: Pilot evaluation in F98-glioma bearing rats and dose calculations in a human phantom","volume":"27","author":"Sotiropoulos","year":"2021","journal-title":"Clin Transl Radiat Oncol"},{"issue":"25","key":"10.1016\/j.zemedi.2026.09.004_b58","doi-asserted-by":"crossref","first-page":"9709","DOI":"10.1073\/pnas.0603567103","article-title":"Interlaced x-ray microplanar beams: A radiosurgery approach with clinical potential","volume":"103","author":"Dilmanian","year":"2006","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.zemedi.2026.09.004_b59","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2015.00269","article-title":"Charged particle therapy with mini-segmented beams","volume":"5","author":"Dilmanian","year":"2015","journal-title":"Front Oncol"},{"issue":"12","key":"10.1016\/j.zemedi.2026.09.004_b60","doi-asserted-by":"crossref","first-page":"7108","DOI":"10.1118\/1.4935868","article-title":"Proton minibeam radiation therapy: Experimental dosimetry evaluation","volume":"42","author":"Peucelle","year":"2015","journal-title":"Med Phys"},{"key":"10.1016\/j.zemedi.2026.09.004_b61","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.111050","article-title":"Probing the therapeutic window of proton minibeam radiotherapy using dose-response curves in a mouse model","volume":"211","author":"Reaz","year":"2025","journal-title":"Radiother Oncol"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b62","doi-asserted-by":"crossref","first-page":"11368","DOI":"10.1038\/s41598-020-68015-0","article-title":"Pilot study of neurologic toxicity in mice after proton minibeam therapy","volume":"10","author":"Eley","year":"2020","journal-title":"Sci Rep"},{"issue":"6\u20137","key":"10.1016\/j.zemedi.2026.09.004_b63","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.canrad.2019.08.001","article-title":"Spatial fractionation of the dose in proton therapy: Proton minibeam radiation therapy","volume":"23","author":"De Marzi","year":"2019","journal-title":"Cancer\/Radioth\u00e9rapie"},{"issue":"4","key":"10.1016\/j.zemedi.2026.09.004_b64","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1002\/mp.12131","article-title":"Optimization of the mechanical collimation for minibeam generation in proton minibeam radiation therapy","volume":"44","author":"Guardiola","year":"2017","journal-title":"Med Phys"},{"issue":"13","key":"10.1016\/j.zemedi.2026.09.004_b65","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/ade04b","article-title":"Commissioning of a multislit collimator system for experimental pMBRT studies with uniform target dose","volume":"70","author":"Reaz","year":"2025","journal-title":"Phys Med Biol"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b66","doi-asserted-by":"crossref","first-page":"18321","DOI":"10.1038\/s41598-021-97941-w","article-title":"A scanning dynamic collimator for spot-scanning proton minibeam production","volume":"11","author":"Sotiropoulos","year":"2021","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b67","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3390\/instruments7020018","article-title":"Investigating slit-collimator-produced carbon ion minibeams with high-resolution CMOS sensors","volume":"7","author":"Volz","year":"2023","journal-title":"Instruments"},{"key":"10.1016\/j.zemedi.2026.09.004_b68","doi-asserted-by":"crossref","DOI":"10.3389\/fphy.2021.595721","article-title":"Monte Carlo comparison of proton and helium-ion minibeam generation techniques","volume":"9","author":"Schneider","year":"2021","journal-title":"Front Phys"},{"issue":"1\u20134","key":"10.1016\/j.zemedi.2026.09.004_b69","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0168-583X(01)00549-3","article-title":"The Munich microprobe SNAKE: First results using 20 MeV protons and 90 MeV sulfur ions","volume":"181","author":"Datzmann","year":"2001","journal-title":"Nucl Instruments Methods Phys Res Sect B: Beam Interactions Mater Atoms"},{"key":"10.1016\/j.zemedi.2026.09.004_b70","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ejmp.2019.12.016","article-title":"Minibeam radiation therapy at a conventional irradiator: Dose-calculation engine and first tumor-bearing animals irradiation","volume":"69","author":"Gonz\u00e1lez","year":"2020","journal-title":"Phys Medica"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b71","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ejmp.2013.02.005","article-title":"Monte Carlo-based dose calculation engine for minibeam radiation therapy","volume":"30","author":"Mart\u00ednez-Rovira","year":"2014","journal-title":"Phys Medica"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b72","doi-asserted-by":"crossref","first-page":"29926","DOI":"10.1038\/s41598-025-15281-5","article-title":"Development of a preclinical X-rays minibeam Monte Carlo treatment planning system","volume":"15","author":"Pizzardi","year":"2025","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b73","doi-asserted-by":"crossref","first-page":"7025","DOI":"10.1038\/s41598-020-63975-9","article-title":"First proton minibeam radiation therapy treatment plan evaluation","volume":"10","author":"Lansonneur","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.zemedi.2026.09.004_b74","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2024.1421869","article-title":"Comprehensive dosimetric commissioning of proton minibeam radiotherapy on a single gantry proton system","volume":"14","author":"Lin","year":"2024","journal-title":"Front Oncol"},{"issue":"4","key":"10.1016\/j.zemedi.2026.09.004_b75","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1134\/S1063779624700606","article-title":"Proton and carbon-ion minibeam therapy: From modeling to treatment","volume":"55","author":"Pshenichnov","year":"2024","journal-title":"Phys Part Nucl"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b76","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1002\/mp.17869","article-title":"A carbon ion minibeam treatment planning method with scissor beams","volume":"52","author":"Wu","year":"2025","journal-title":"Med Phys"},{"issue":"5","key":"10.1016\/j.zemedi.2026.09.004_b77","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1002\/mp.12175","article-title":"Theoretical dosimetric evaluation of carbon and oxygen minibeam radiation therapy","volume":"44","author":"Gonz\u00e1lez","year":"2017","journal-title":"Med Phys"},{"issue":"8","key":"10.1016\/j.zemedi.2026.09.004_b78","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1002\/mp.12383","article-title":"Carbon and oxygen minibeam radiation therapy: An experimental dosimetric evaluation","volume":"44","author":"Mart\u00ednez-Rovira","year":"2017","journal-title":"Med Phys"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b79","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.ijrobp.2011.12.025","article-title":"Interleaved carbon minibeams: An experimental radiosurgery method with clinical potential","volume":"84","author":"Dilmanian","year":"2012","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"issue":"8","key":"10.1016\/j.zemedi.2026.09.004_b80","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1002\/mp.13646","article-title":"Improving the dose distributions in minibeam radiation therapy: Helium ions vs protons","volume":"46","author":"Schneider","year":"2019","journal-title":"Med Phys"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b81","doi-asserted-by":"crossref","DOI":"10.1088\/2057-1976\/ada964","article-title":"Quantitative assessment of delivered dose in carbon ion spatially fractionated radiotherapy (C-SFRT) and biological response to C-SFRT","volume":"11","author":"Tsubouchi","year":"2025","journal-title":"Biomed Phys Eng Express"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b82","doi-asserted-by":"crossref","DOI":"10.1002\/mp.70516","article-title":"Cell survival comparison of proton, helium, and carbon ion interlaced minibeams in water phantom simulations","volume":"53","author":"Rousseti","year":"2026","journal-title":"Med Phys"},{"key":"10.1016\/j.zemedi.2026.09.004_b83","article-title":"From pre-clinical studies to human treatment with proton-minibeam radiation therapy: adapted Idea, Development, Exploration, Assessment and Long-term evaluation (IDEAL) framework for innovation in radiotherapy","volume":"52","author":"Jouglar","year":"2025","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.zemedi.2026.09.004_b84","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.110980","article-title":"Proton minibeam radiation therapy: A promising alternative for brain re-irradiations","volume":"209","author":"Prezado","year":"2025","journal-title":"Radiother Oncol"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b85","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.3390\/cancers13061356","article-title":"A potential renewed use of very heavy ions for therapy: Neon minibeam radiation therapy","volume":"13","author":"Prezado","year":"2021","journal-title":"Cancers"},{"key":"10.1016\/j.zemedi.2026.09.004_b86","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmp.2025.104894","article-title":"Real-time dose measurement in minibeam radiotherapy using radioluminescence imaging","volume":"130","author":"Marson","year":"2025","journal-title":"Phys Medica"},{"issue":"7","key":"10.1016\/j.zemedi.2026.09.004_b87","doi-asserted-by":"crossref","DOI":"10.1002\/mp.17893","article-title":"Characterizing diamond detectors for various dose and dose rate measurements in scanned carbon and oxygen beams","volume":"52","author":"Karle","year":"2025","journal-title":"Med Phys"},{"issue":"12","key":"10.1016\/j.zemedi.2026.09.004_b88","doi-asserted-by":"crossref","first-page":"9230","DOI":"10.1002\/mp.17370","article-title":"A review of diamond dosimeters in advanced radiotherapy techniques","volume":"51","author":"Angelou","year":"2024","journal-title":"Med Phys"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b89","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.zemedi.2015.08.003","article-title":"The role of a microDiamond detector in the dosimetry of proton pencil beams","volume":"26","author":"Gom\u00e0","year":"2016","journal-title":"Z Med Phys"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b90","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3390\/instruments7010009","article-title":"A beam monitor for ion beam therapy based on HV-CMOS pixel detectors","volume":"7","author":"Dierlamm","year":"2023","journal-title":"Instruments"},{"issue":"5","key":"10.1016\/j.zemedi.2026.09.004_b91","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1088\/1361-6560\/aa5bc9","article-title":"Real-time detection of fast and thermal neutrons in radiotherapy with CMOS sensors","volume":"62","author":"Arbor","year":"2017","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.zemedi.2026.09.004_b92","series-title":"International conference on signal processing and communication","first-page":"392","article-title":"Effect of temperature dependence on performance of Digital CMOS circuit technologies","author":"Kalra","year":"2023"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b93","doi-asserted-by":"crossref","DOI":"10.1016\/j.net.2026.104210","article-title":"Investigation of \u03b1 particle induced damage and annealing behavior in CMOS active pixel sensors for radiation detection applications","volume":"58","author":"Li","year":"2026","journal-title":"Nucl Eng Technol"},{"issue":"24","key":"10.1016\/j.zemedi.2026.09.004_b94","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/aaf34a","article-title":"LET dependent response of GafChromic films investigated with MeV ion beams","volume":"63","author":"Grilj","year":"2018","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.zemedi.2026.09.004_b95","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.phro.2022.08.001","article-title":"Linear energy transfer-independent calibration of radiochromic film for carbon-ion beams","volume":"23","author":"Tashiro","year":"2022","journal-title":"Phys Imaging Radiat Oncol"},{"key":"10.1016\/j.zemedi.2026.09.004_b96","doi-asserted-by":"crossref","DOI":"10.1016\/j.radmeas.2022.106844","article-title":"A review on reference dosimetry in radiation therapy with proton and light ion beams: status and impact of new developments","volume":"157","author":"Vedelago","year":"2022","journal-title":"Radiat Meas"},{"key":"10.1016\/j.zemedi.2026.09.004_b97","series-title":"Absorbed dose determination in external beam radiotherapy","isbn-type":"print","author":"IAEA","year":"2024","ISBN":"https:\/\/id.crossref.org\/isbn\/9789201460226"},{"key":"10.1016\/j.zemedi.2026.09.004_b98","doi-asserted-by":"crossref","DOI":"10.3389\/fphy.2020.598257","article-title":"Secondary radiation in ion therapy and theranostics: A review","volume":"8","author":"Nandy","year":"2021","journal-title":"Front Phys"},{"key":"10.1016\/j.zemedi.2026.09.004_b99","doi-asserted-by":"crossref","DOI":"10.1016\/j.radmeas.2024.107214","article-title":"Secondary neutrons in proton and light ion beam therapy: a review of current status, needs and potential solutions","volume":"176","author":"Vedelago","year":"2024","journal-title":"Radiat Meas"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b100","doi-asserted-by":"crossref","DOI":"10.1002\/mp.70303","article-title":"Fluorescent nuclear track detectors for out-of-field neutron dosimetry in proton therapy","volume":"53","author":"Schmidt","year":"2026","journal-title":"Med Phys"},{"issue":"21","key":"10.1016\/j.zemedi.2026.09.004_b101","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/ae128f","article-title":"Achieving high-resolution spatial mapping of dose and linear energy transfer in ion-beam therapy","volume":"70","author":"Jensen","year":"2025","journal-title":"Phys Med Biol"},{"issue":"23","key":"10.1016\/j.zemedi.2026.09.004_b102","doi-asserted-by":"crossref","first-page":"4013","DOI":"10.3390\/cancers16234013","article-title":"Challenges for the implementation of primary standard dosimetry in proton minibeam radiation therapy","volume":"16","author":"Cotterill","year":"2024","journal-title":"Cancers"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b103","doi-asserted-by":"crossref","first-page":"06TR01","DOI":"10.1088\/1361-6560\/ad278f","article-title":"Validation of complex radiotherapy techniques using polymer gel dosimetry","volume":"69","author":"Karger","year":"2024","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.zemedi.2026.09.004_b104","doi-asserted-by":"crossref","DOI":"10.1016\/j.radmeas.2024.107175","article-title":"Carbon ion mono-energetic and spread-out Bragg peak measurements using nanocomposite Fricke gel dosimeters with LET-independent response","volume":"176","author":"Bayer","year":"2024","journal-title":"Radiat Meas"},{"key":"10.1016\/j.zemedi.2026.09.004_b105","doi-asserted-by":"crossref","DOI":"10.1177\/1533033819870208","article-title":"A systematic review on 3D-printed imaging and dosimetry phantoms in radiation therapy","volume":"18","author":"Tino","year":"2019","journal-title":"Technol Cancer Res Treat"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b106","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00411-021-00895-w","article-title":"Modelling and measurements of distributions in an adult human phantom undergoing proton scanning beam radiotherapy: lung- and prostate-located tumours","volume":"60","author":"Puchalska","year":"2021","journal-title":"Radiat Environ Biophys"},{"key":"10.1016\/j.zemedi.2026.09.004_b107","series-title":"Tissue equivalence of some phantom materials for proton beams","author":"Vasiliev","year":"2010"},{"key":"10.1016\/j.zemedi.2026.09.004_b108","series-title":"IPEM-IOP series in Physics and Engineering in Medicine and Biology series","isbn-type":"print","doi-asserted-by":"crossref","DOI":"10.1088\/2053-2563\/aae197","article-title":"Anthropomorphic phantoms in image quality and patient dose optimization: A EUTEMPE network book","author":"Bliznakova","year":"2018","ISBN":"https:\/\/id.crossref.org\/isbn\/9780750313230"},{"key":"10.1016\/j.zemedi.2026.09.004_b109","series-title":"Alderson radiation therapy phantom","author":"phantoms","year":"2026"},{"key":"10.1016\/j.zemedi.2026.09.004_b110","series-title":"Motion managment phantoms","author":"Sunnuclear","year":"2026"},{"key":"10.1016\/j.zemedi.2026.09.004_b111","series-title":"Repiratory motion phantom","author":"ModusQA","year":"2026"},{"issue":"20","key":"10.1016\/j.zemedi.2026.09.004_b112","doi-asserted-by":"crossref","first-page":"8136","DOI":"10.1088\/1361-6560\/aa86ea","article-title":"Advanced Radiation DOSimetry phantom (ARDOS): a versatile breathing phantom for 4D radiation therapy and medical imaging","volume":"62","author":"Kostiukhina","year":"2017","journal-title":"Phys Med Biol"},{"issue":"7","key":"10.1016\/j.zemedi.2026.09.004_b113","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.3390\/cancers14071788","article-title":"The influence of motion on the delivery accuracy when comparing actively scanned carbon ions versus protons at a synchrotron-based radiotherapy facility","volume":"14","author":"Lebbink","year":"2022","journal-title":"Cancers"},{"issue":"20","key":"10.1016\/j.zemedi.2026.09.004_b114","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6560\/ad7d59","article-title":"Real-time delivered dose assessment in carbon ion therapy of moving targets","volume":"69","author":"Galeone","year":"2024","journal-title":"Phys Med Biol"},{"issue":"5","key":"10.1016\/j.zemedi.2026.09.004_b115","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.ijrobp.2024.06.035","article-title":"Minibeam radiation therapy treatment (MBRT): Commissioning and first clinical implementation","volume":"120","author":"Grams","year":"2024","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"key":"10.1016\/j.zemedi.2026.09.004_b116","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.767832","article-title":"Study on motion management of pancreatic cancer treated by CyberKnife","volume":"11","author":"Jing","year":"2021","journal-title":"Front Oncol"},{"issue":"6","key":"10.1016\/j.zemedi.2026.09.004_b117","doi-asserted-by":"crossref","DOI":"10.1002\/acm2.13930","article-title":"Evaluating motion of pancreatic tumors and anatomical surrogates using cine MRI in 0.35T MRgRT under free breathing conditions","volume":"24","author":"Lewis","year":"2023","journal-title":"J Appl Clin Med Phys"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b118","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijrobp.2024.07.402","article-title":"Clinical commissioning of orthovoltage-based minibeam radiation therapy (MBRT)","volume":"120","author":"Mateus","year":"2024","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"issue":"5","key":"10.1016\/j.zemedi.2026.09.004_b119","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1002\/mp.14786","article-title":"Gastrointestinal 4D MRI with respiratory motion correction","volume":"48","author":"Johansson","year":"2021","journal-title":"Med Phys"},{"issue":"4","key":"10.1016\/j.zemedi.2026.09.004_b120","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.ijrobp.2008.10.055","article-title":"Impact of intrafractional bowel gas movement on carbon ion beam dose distribution in pancreatic radiotherapy","volume":"73","author":"Kumagai","year":"2009","journal-title":"Int J Radiat Oncology*Biology*Physics"},{"key":"10.1016\/j.zemedi.2026.09.004_b121","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/519602","article-title":"Respiratory gating for radiotherapy: Main technical aspects and clinical benefits","volume":"2013","author":"Giraud","year":"2013","journal-title":"ISRN Pulmonol"},{"issue":"2","key":"10.1016\/j.zemedi.2026.09.004_b122","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s12194-013-0208-3","article-title":"Technical approach to individualized respiratory-gated carbon-ion therapy for mobile organs","volume":"6","author":"Tashiro","year":"2013","journal-title":"Radiol Phys Technol"},{"issue":"9161","key":"10.1016\/j.zemedi.2026.09.004_b123","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/S0140-6736(99)00700-X","article-title":"Real-time tumour-tracking radiotherapy","volume":"353","author":"Shirato","year":"1999","journal-title":"Lancet"},{"issue":"19","key":"10.1016\/j.zemedi.2026.09.004_b124","doi-asserted-by":"crossref","first-page":"5707","DOI":"10.1088\/0031-9155\/59\/19\/5707","article-title":"First experimental results of motion mitigation by continuous line scanning of protons","volume":"59","author":"Sch\u00e4tti","year":"2014","journal-title":"Phys Med Biol"},{"issue":"5","key":"10.1016\/j.zemedi.2026.09.004_b125","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1118\/1.4916662","article-title":"Motion mitigation for lung cancer patients treated with active scanning proton therapy","volume":"42","author":"Grassberger","year":"2015","journal-title":"Med Phys"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b126","first-page":"14","article-title":"pMB FLASH - Status and perspectives of combining proton minibeam with FLASH radiotherapy","author":"Reindl","year":"2019","journal-title":"J Cancer Immunol"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b127","doi-asserted-by":"crossref","first-page":"7803","DOI":"10.1038\/s41598-026-36739-0","article-title":"Experimental characterization of proton minibeam therapy delivery under FLASH dose-rate conditions","volume":"16","author":"Lin","year":"2026","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.zemedi.2026.09.004_b128","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3390\/radiation5010003","article-title":"Minibeam spatially-fractionated radiation therapy is superior to uniform dose radiation therapy for abscopal effect when combined with PD-L1 checkpoint inhibitor immunotherapy in a dual tumor murine mammary carcinoma model","volume":"5","author":"Rivera","year":"2025","journal-title":"Radiation"},{"issue":"4","key":"10.1016\/j.zemedi.2026.09.004_b129","article-title":"Minibeam radiation therapy for recurrent mucosal melanoma: An eye-opening response","volume":"9","author":"Jacobson","year":"2025","journal-title":"Mayo Clin Proc: Innov Qual & Outcomes"}],"container-title":["Zeitschrift f\u00fcr Medizinische Physik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939388926000978?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939388926000978?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:33:15Z","timestamp":1792438395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939388926000978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":129,"alternative-id":["S0939388926000978"],"URL":"https:\/\/doi.org\/10.1016\/j.zemedi.2026.09.004","relation":{},"ISSN":["0939-3889"],"issn-type":[{"value":"0939-3889","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Review on carbon ion minibeam radiotherapy: Dosimetry, dynamic phantoms and radiobiology","name":"articletitle","label":"Article Title"},{"value":"Zeitschrift f\u00fcr Medizinische Physik","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.zemedi.2026.09.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier GmbH on behalf of DGMP, \u00d6GMP and SSRMP.","name":"copyright","label":"Copyright"}]}}