{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:20:14Z","timestamp":1761920414068,"version":"build-2065373602"},"reference-count":11,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Lancet Infectious Diseases"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/s1473-3099(18)30055-0","type":"journal-article","created":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T02:17:58Z","timestamp":1517537878000},"page":"479-480","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Could omics unlock the secret of surviving tuberculous meningitis?"],"prefix":"10.1016","volume":"18","author":[{"given":"Sarah J","family":"Dunstan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxine","family":"Caws","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S1473-3099(18)30055-0_bib1","first-page":"5","article-title":"The pathogenesis of tuberculous meningitis","volume":"52","author":"Rich","year":"1933","journal-title":"Bull Johns Hopkins Hosp"},{"key":"10.1016\/S1473-3099(18)30055-0_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1468-1331.2006.01534.x","article-title":"Predictors of long-term neurological sequelae of tuberculous meningitis: a multivariate analysis","volume":"14","author":"Kalita","year":"2007","journal-title":"Eur J Neurol"},{"key":"10.1016\/S1473-3099(18)30055-0_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/S1473-3099(18)30053-7","article-title":"Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study","author":"van Laarhoven","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/S1473-3099(18)30055-0_bib4","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1128\/JCM.42.1.378-379.2004","article-title":"Improving the bacteriological diagnosis of tuberculous meningitis","volume":"42","author":"Thwaites","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/S1473-3099(18)30055-0_bib5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nrneurol.2017.120","article-title":"Tuberculous meningitis","volume":"13","author":"Wilkinson","year":"2017","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/S1473-3099(18)30055-0_bib6","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.cell.2011.12.023","article-title":"Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections","volume":"148","author":"Tobin","year":"2012","journal-title":"Cell"},{"key":"10.1016\/S1473-3099(18)30055-0_bib7","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1128\/iai.57.3.845-849.1989","article-title":"Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages","volume":"57","author":"Murray","year":"1989","journal-title":"Infect Immun"},{"key":"10.1016\/S1473-3099(18)30055-0_bib8","doi-asserted-by":"crossref","first-page":"5105","DOI":"10.1128\/IAI.00668-07","article-title":"Severe tryptophan starvation blocks onset of conventional persistence and reduces reactivation of Chlamydia trachomatis","volume":"75","author":"Leonhardt","year":"2007","journal-title":"Infect Immun"},{"key":"10.1016\/S1473-3099(18)30055-0_bib9","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/nchembio.2420","article-title":"A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase","volume":"13","author":"Wellington","year":"2017","journal-title":"Nat Chem Biol"},{"key":"10.1016\/S1473-3099(18)30055-0_bib10","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s13059-017-1215-1","article-title":"Multi-omics approaches to disease","volume":"18","author":"Hasin","year":"2017","journal-title":"Genome Biol"},{"key":"10.1016\/S1473-3099(18)30055-0_bib11","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbx066","article-title":"Network approaches to systems biology analysis of complex disease: integrative methods for multi-omics data","author":"Yan","year":"2017","journal-title":"Brief Bioinform"}],"container-title":["The Lancet Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473309918300550?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473309918300550?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T09:25:01Z","timestamp":1761470701000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1473309918300550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["S1473309918300550"],"URL":"https:\/\/doi.org\/10.1016\/s1473-3099(18)30055-0","relation":{},"ISSN":["1473-3099"],"issn-type":[{"type":"print","value":"1473-3099"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Could omics unlock the secret of surviving tuberculous meningitis?","name":"articletitle","label":"Article Title"},{"value":"The Lancet Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S1473-3099(18)30055-0","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/S1473-3099(18)30053-7","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}