{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T22:59:05Z","timestamp":1770505145268,"version":"3.49.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1984,8,1]],"date-time":"1984-08-01T00:00:00Z","timestamp":460166400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[1984,8]]},"DOI":"10.1016\/0006-291x(84)90424-8","type":"journal-article","created":{"date-parts":[[2008,9,12]],"date-time":"2008-09-12T17:01:21Z","timestamp":1221238881000},"page":"377-384","source":"Crossref","is-referenced-by-count":141,"title":["Reduction of epidermal growth factor receptor affinity by heterologous ligands: Evidence for a mechanism involving the breakdown of phosphoinositides and the activation of protein kinase C"],"prefix":"10.1016","volume":"123","author":[{"given":"Kenneth D.","family":"Brown","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Blay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin F.","family":"Irvine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Heslop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Berridge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0006-291X(84)90424-8_BIB1","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/0006-291X(83)90666-6","volume":"114","author":"Bowen-Pope","year":"1983","journal-title":"Biochem. Biophys. Res. Comm"},{"key":"10.1016\/0006-291X(84)90424-8_BIB2","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1083\/jcb.96.3.679","volume":"96","author":"Bowen-Pope","year":"1983","journal-title":"J. Cell Biol"},{"key":"10.1016\/0006-291X(84)90424-8_BIB3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/BF01172876","volume":"3","author":"Brown","year":"1983","journal-title":"Biosci. Rep"},{"key":"10.1016\/0006-291X(84)90424-8_BIB4","doi-asserted-by":"crossref","first-page":"11689","DOI":"10.1016\/S0021-9258(17)44283-9","volume":"258","author":"Collins","year":"1983","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB5","doi-asserted-by":"crossref","first-page":"3680","DOI":"10.1016\/S0021-9258(18)34834-8","volume":"257","author":"Rozengurt","year":"1982","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB6","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1042\/bj2120465","volume":"212","author":"Brown","year":"1983","journal-title":"Biochem. J"},{"key":"10.1016\/0006-291X(84)90424-8_BIB7","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1042\/bj2190609","volume":"219","author":"Brown","year":"1984","journal-title":"Biochem. J"},{"key":"10.1016\/0006-291X(84)90424-8_BIB8","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/S0021-9258(19)70033-7","volume":"256","author":"Rozengurt","year":"1981","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB9","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/0006-291X(79)90221-3","volume":"86","author":"Brown","year":"1979","journal-title":"Biochem. Biophys. Res. Comm"},{"key":"10.1016\/0006-291X(84)90424-8_BIB10","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/279387a0","volume":"279","author":"Shoyab","year":"1979","journal-title":"Nature"},{"key":"10.1016\/0006-291X(84)90424-8_BIB11","first-page":"5168","volume":"76","author":"Lee","year":"1979"},{"key":"10.1016\/0006-291X(84)90424-8_BIB12","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/jcp.1041090112","volume":"109","author":"Dicker","year":"1981","journal-title":"J. Cell Physiol"},{"key":"10.1016\/0006-291X(84)90424-8_BIB13","first-page":"1284","volume":"76","author":"Rozengurt","year":"1979"},{"key":"10.1016\/0006-291X(84)90424-8_BIB14","first-page":"2936","volume":"80","author":"Rozengurt","year":"1983"},{"key":"10.1016\/0006-291X(84)90424-8_BIB15","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0968-0004(83)90074-9","volume":"8","author":"Michell","year":"1983","journal-title":"Trends Biochem. Sci"},{"key":"10.1016\/0006-291X(84)90424-8_BIB16","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/308693a0","volume":"308","author":"Nishizuka","year":"1984","journal-title":"Nature"},{"key":"10.1016\/0006-291X(84)90424-8_BIB17","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1042\/bj2200345","volume":"220","author":"Berridge","year":"1984","journal-title":"Biochem. J"},{"key":"10.1016\/0006-291X(84)90424-8_BIB18","doi-asserted-by":"crossref","first-page":"7847","DOI":"10.1016\/S0021-9258(18)34459-4","volume":"257","author":"Castagna","year":"1982","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB19","first-page":"36","volume":"80","author":"Niedel","year":"1983"},{"key":"10.1016\/0006-291X(84)90424-8_BIB20","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/S0006-291X(83)80157-0","volume":"111","author":"Ashendel","year":"1983","journal-title":"Biochem. Biophys. Res. Comm"},{"key":"10.1016\/0006-291X(84)90424-8_BIB21","doi-asserted-by":"crossref","first-page":"11442","DOI":"10.1016\/S0021-9258(17)44245-1","volume":"258","author":"Kikkawa","year":"1983","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB22","doi-asserted-by":"crossref","first-page":"7609","DOI":"10.1016\/S0021-9258(19)44568-7","volume":"247","author":"Savage","year":"1972","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB23","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1042\/bj2120473","volume":"212","author":"Berridge","year":"1983","journal-title":"Biochem. J"},{"key":"10.1016\/0006-291X(84)90424-8_BIB24","author":"Berridge","year":"1984","journal-title":"Biochem. J"},{"key":"10.1016\/0006-291X(84)90424-8_BIB25","doi-asserted-by":"crossref","first-page":"12329","DOI":"10.1016\/S0021-9258(18)43275-9","volume":"256","author":"Habenicht","year":"1981","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB26","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1016\/S0021-9258(18)32782-0","volume":"258","author":"Rhodes","year":"1983","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB27","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1042\/bj2120733","volume":"212","author":"Creba","year":"1983","journal-title":"Biochem. J"},{"key":"10.1016\/0006-291X(84)90424-8_BIB28","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1016\/S0021-9258(17)43389-8","volume":"259","author":"Cochet","year":"1984","journal-title":"J. Biol. Chem"},{"key":"10.1016\/0006-291X(84)90424-8_BIB29","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0014-5793(83)80312-3","volume":"164","author":"Logsdon","year":"1983","journal-title":"FEBS Lett"},{"key":"10.1016\/0006-291X(84)90424-8_BIB30","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0024-3205(83)90131-5","volume":"33","author":"Korc","year":"1983","journal-title":"Life Sci"},{"key":"10.1016\/0006-291X(84)90424-8_BIB31","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1042\/bj2190655","volume":"219","author":"Rubin","year":"1984","journal-title":"Biochem. J"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0006291X84904248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0006291X84904248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T11:03:48Z","timestamp":1631790228000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0006291X84904248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,8]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1984,8]]}},"alternative-id":["0006291X84904248"],"URL":"https:\/\/doi.org\/10.1016\/0006-291x(84)90424-8","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[1984,8]]}}}