{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T21:31:37Z","timestamp":1771623097379,"version":"3.50.1"},"reference-count":139,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1970,9,1]],"date-time":"1970-09-01T00:00:00Z","timestamp":20995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Research"],"published-print":{"date-parts":[[1970,9]]},"DOI":"10.1016\/0006-8993(70)90345-8","type":"journal-article","created":{"date-parts":[[2003,4,24]],"date-time":"2003-04-24T21:39:53Z","timestamp":1051220393000},"page":"1-21","source":"Crossref","is-referenced-by-count":360,"title":["What is the signal for chromatolysis?"],"prefix":"10.1016","volume":"23","author":[{"given":"B.G.","family":"Cragg","sequence":"first","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/0006-8993(70)90345-8_bib1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/cne.901350202","article-title":"Degeneration and regeneration of hypothalamic nerve fibers in the neurohypophysis after pituitary stalk section in the ferret","volume":"135","author":"Adams","year":"1969","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib2","first-page":"143","article-title":"On the presence of prelabelled cells in the hypoglossal nucleus following transection of the hypoglossal nerve","volume":"163","author":"Adrian","year":"1969","journal-title":"Anat. Rec."},{"key":"10.1016\/0006-8993(70)90345-8_bib3","first-page":"1","article-title":"Maturation of regenerating nerve fibres with various peripheral connexions","volume":"81","author":"Aitken","year":"1947","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib4","first-page":"121","article-title":"Retrograde changes in fibre size following nerve section","volume":"96","author":"Aitken","year":"1962","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib5","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1113\/jphysiol.1902.sp000931","article-title":"The nature of the lesions which hinder the development of nerve cells and their processes","volume":"28","author":"Anderson","year":"1902","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib6","first-page":"186","article-title":"On the changes in histological structure of the cochlea of the cat following section of the VIIIth nerve","volume":"122","author":"Ashcroft","year":"1937"},{"key":"10.1016\/0006-8993(70)90345-8_bib7","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1113\/jphysiol.1959.sp006233","article-title":"A study of supersensitivity in denervated mammalian skeletal muscle","volume":"147","author":"Axellson","year":"1959","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib8","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1113\/jphysiol.1969.sp008720","article-title":"The redistribution of cytochrome oxidase, noradrenaline and adenosine triphosphate in adrenergic nerves constricted at two points","volume":"200","author":"Banks","year":"1969","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib9","first-page":"538","article-title":"Sprouting and degeneration of mammalian motor axons in normal and deafferentated skeletal muscle","volume":"163","author":"Barker","year":"1966"},{"key":"10.1016\/0006-8993(70)90345-8_bib10","series-title":"Axoplasmic transport","first-page":"309","volume":"5","year":"1967"},{"key":"10.1016\/0006-8993(70)90345-8_bib11","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/cne.900890203","article-title":"A quantitative study of certain morphological changes in spinal motor neurons during axon reaction","volume":"89","author":"Barr","year":"1948","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib12","first-page":"171","article-title":"The behaviour of nuclear structures during depletion and restoration of Nissl material in motor neurons","volume":"85","author":"Barr","year":"1951","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib13","first-page":"150","article-title":"Ultrastructural observations on axon reaction in feline spinal motoneurones","volume":"163","author":"Barron","year":"1969","journal-title":"Anat. Rec."},{"key":"10.1016\/0006-8993(70)90345-8_bib14","first-page":"22","article-title":"Some changes in the hypothalamus and proximal pituitary stalk after stalk section","volume":"146","author":"Beck","year":"1959","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib15","first-page":"33","article-title":"A discussion on retrograde changes in nerve fibres","volume":"Vol. 14","author":"Beresford","year":"1965"},{"key":"10.1016\/0006-8993(70)90345-8_bib16","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1210\/endo-56-6-704","article-title":"The reorganization of the neurohypophysial stalk following hypophysectomy in the rat","volume":"56","author":"Billenstien","year":"1955","journal-title":"Endocrinology"},{"key":"10.1016\/0006-8993(70)90345-8_bib17","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BF00325030","article-title":"Displacement of synaptic terminals from regenerating motoneurons by microglial cells","volume":"85","author":"Blinzinger","year":"1968","journal-title":"Z. Zellforsch."},{"key":"10.1016\/0006-8993(70)90345-8_bib18","first-page":"79","article-title":"The rate of progression of poliomyelitis virus in nerves","volume":"69","author":"Bodian","year":"1941","journal-title":"Bull. John Hopk. Hosp."},{"key":"10.1016\/0006-8993(70)90345-8_bib19","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1084\/jem.81.5.469","article-title":"The regenerative cycle of motor neurons, with special reference to phosphatase activity","volume":"81","author":"Bodian","year":"1945","journal-title":"J. exp. Med."},{"key":"10.1016\/0006-8993(70)90345-8_bib20","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1471-4159.1957.tb12088.x","article-title":"The chemical changes in regenerating neurons","volume":"1","author":"Brattg\u00e5rd","year":"1957","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib21","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1001\/archneurpsyc.1940.02280010054003","article-title":"Modification of Gudden method for study of cerebral localization","volume":"43","author":"Brodal","year":"1940","journal-title":"Arch. Neurol. Psychiat. (Chic.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib22","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1113\/jphysiol.1954.sp005067","article-title":"The action of botulinum toxin on motor nerve filaments","volume":"123","author":"Brooks","year":"1954","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib23","first-page":"28P","article-title":"Failure of ganglionic transmission after post-ganglionic nerve section","volume":"117","author":"Brown","year":"1952","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib24","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1113\/jphysiol.1954.sp005071","article-title":"The effect of degenerative section of ganglionic axons on transmission through the ganglion","volume":"123","author":"Brown","year":"1954","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib25","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/cne.900450104","article-title":"Studies in degeneration of peripheral nerves","volume":"45","author":"Bucy","year":"1928","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib26","first-page":"402","article-title":"Trans-synaptic retrograde degeneration in the visual system in primates","volume":"26","author":"Buren","year":"1963","journal-title":"J. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib27","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/BF00686415","article-title":"Peripheral chromatolysis after transection of mouse facial nerve","volume":"2","author":"Cammermeyer","year":"1963","journal-title":"Acta neuropath. (Berl.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib28","first-page":"1","article-title":"Juxtavascular karyokinesis and microglia cell proliferation during retrograde reaction in the mouse facial nucleus","volume":"38","author":"Cammermeyer","year":"1965","journal-title":"Ergebn. Anat. Entwickl.-Gesch."},{"key":"10.1016\/0006-8993(70)90345-8_bib29","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/ar.1090880103","article-title":"The effects of retrograde degeneration upon reflex activity of ventral horn neurones","volume":"88","author":"Campbell","year":"1944","journal-title":"Anat. Rec."},{"key":"10.1016\/0006-8993(70)90345-8_bib30","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF02135957","article-title":"Regeneration of feline dorsal roots","volume":"23","author":"Carlsson","year":"1967","journal-title":"Experientia (Basel)"},{"key":"10.1016\/0006-8993(70)90345-8_bib31","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/cne.901350203","article-title":"Cell changes in sensory ganglia following proximal and distal nerve section in the monkey","volume":"135","author":"Carmel","year":"1969","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib32","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/cne.900940203","article-title":"Quantitative effects of the peripheral innervation area on nerves and spinal ganglion cells","volume":"94","author":"Cavanaugh","year":"1951","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib33","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/cne.901090205","article-title":"Retrograde reaction in motoneurone dendrites following ventral root section in the frog","volume":"109","author":"Cerf","year":"1958","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib34","first-page":"299","article-title":"Inquiries into the anatomical basis of olfactory discrimination","volume":"146","author":"Clarke","year":"1957"},{"key":"10.1016\/0006-8993(70)90345-8_bib35","first-page":"269","article-title":"Retrograde degeneration of axon and soma in the nervous system","volume":"Vol. 1","author":"Cole","year":"1968"},{"key":"10.1016\/0006-8993(70)90345-8_bib36","first-page":"114","article-title":"An experimental study of the relation between the medial mammillary nucleus and the cingulate cortex","volume":"143","author":"Cowan","year":"1954"},{"key":"10.1016\/0006-8993(70)90345-8_bib37","first-page":"546","article-title":"An experimental study of the avian visual system","volume":"95","author":"Cowan","year":"1961","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib38","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1113\/jphysiol.1961.sp006724","article-title":"Changes in conduction velocity and fibre size proximal peripheral nerve lesions","volume":"157","author":"Cragg","year":"1961","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib39","first-page":"677","article-title":"Obsercations on the accumulation of nor-adrenaline in the proximal and distal parts of peripheral adrenergic nerves after compression","volume":"99","author":"Dahlstr\u00f6m","year":"1965","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib40","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0014-2999(68)90165-9","article-title":"Effect of colchicine on transport of amine storage granules in sympathetic nerves of rat","volume":"5","author":"Dahlstr\u00f6m","year":"1968","journal-title":"Europ. J. Pharmacol."},{"key":"10.1016\/0006-8993(70)90345-8_bib41","first-page":"75","article-title":"Studies of the connexions of the fornix system","volume":"17","author":"Daitz","year":"1954","journal-title":"J. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib42","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1113\/jphysiol.1900.sp000788","article-title":"On some numerical comparisons of the centripetal and centrifugal medullated nerve fibres arising in the spinal ganglia of the mammal","volume":"25","author":"Dale","year":"1900","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib43","first-page":"58","article-title":"An effect of post-synaptic neurons upon presynaptic terminals","volume":"63","author":"Decima","year":"1969"},{"key":"10.1016\/0006-8993(70)90345-8_bib44","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/215657a0","article-title":"\u2018Phagocytic\u2019 lysosomes in chromatolytic neurones","volume":"215","author":"Dixon","year":"1962","journal-title":"Nature (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib45","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/cne.900980104","article-title":"Functional changes in chromatolysed motoneurones","volume":"98","author":"Downman","year":"1953","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib46","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0074-7696(08)60208-9","article-title":"Protein metabolism in nerve cells","volume":"25","author":"Droz","year":"1969","journal-title":"Int. Rev. Cytol."},{"key":"10.1016\/0006-8993(70)90345-8_bib47","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1113\/expphysiol.1968.sp001948","article-title":"The effects of botulinum toxin on the pattern of innervation of skeletal muscle in the mouse","volume":"53","author":"Duchen","year":"1968","journal-title":"Quart. J. exp. Physiol."},{"key":"10.1016\/0006-8993(70)90345-8_bib48","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/00005072-194807000-00002","article-title":"Alteration in the structure of nerves caused by restricting their growth with ligatures","volume":"71","author":"Duncan","year":"1948","journal-title":"J. Neuropath."},{"key":"10.1016\/0006-8993(70)90345-8_bib49","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1113\/jphysiol.1958.sp006041","article-title":"The behaviour of chromatolytic motoneurons studied by intracellular recording","volume":"143","author":"Eccles","year":"1958","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib50","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1152\/jn.1962.25.4.544","article-title":"An investigation into the effect of degenerating primary afferent fibers on the monosynaptic innervation of motoneurones","volume":"25","author":"Eccles","year":"1962","journal-title":"J. Neurophysiol."},{"key":"10.1016\/0006-8993(70)90345-8_bib51","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1086\/399699","article-title":"Collateral nerve regeneration","volume":"28","author":"Edds","year":"1953","journal-title":"Quart. Rev. Biol."},{"key":"10.1016\/0006-8993(70)90345-8_bib52","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1471-4159.1959.tb13331.x","article-title":"Ribonucleic acid changes in the motoneurons of the frog during axon regeneration","volume":"5","author":"Edstr\u00f6m","year":"1959","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib53","first-page":"325","article-title":"The structure and composition of motor, sensory and autonomic nerves and nerve fibers","volume":"Vol. 1","author":"Elfvin","year":"1969"},{"key":"10.1016\/0006-8993(70)90345-8_bib54","first-page":"193","article-title":"A study of silver degeneration methods in the central nervous system","volume":"90","author":"Evans","year":"1956","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib55","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/0024-3205(67)90100-2","article-title":"The time required for innervation of denervated muscles by nerve implants","volume":"6","author":"Fex","year":"1967","journal-title":"Life Sci."},{"key":"10.1016\/0006-8993(70)90345-8_bib56","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1471-4159.1969.tb06845.x","article-title":"Is there a bidirectional transport of noradrenaline in sympathetic nerves?","volume":"16","author":"Geffen","year":"1969","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib57","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1001\/archneurpsyc.1933.02240070094005","article-title":"Chromatolysis of efferent neurons","volume":"29","author":"Geist","year":"1933","journal-title":"Arch. Neurol. (Chic.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib58","first-page":"315","article-title":"L'anatomie fine de la cellule nerveuse","volume":"13","author":"Gehuchten","year":"1897","journal-title":"Cellule"},{"key":"10.1016\/0006-8993(70)90345-8_bib59","first-page":"437","article-title":"Retrograde trans-synaptic degeneration of the inner nuclear layer of the retina","volume":"6","author":"Gills","year":"1967","journal-title":"Invest. Ophthal."},{"key":"10.1016\/0006-8993(70)90345-8_bib60","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1126\/science.148.3667.242","article-title":"Histone regulation of lactic dehydrogenase in embryonic chick brain tissue","volume":"148","author":"Goodwin","year":"1965","journal-title":"Science"},{"key":"10.1016\/0006-8993(70)90345-8_bib61","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BF00236107","article-title":"The lateral cervical nucleus in the cat. IV. A light and electron microscopical study after midbrain lesions with demonstration of indirect Wallerian degeneration at the ultrastructural level","volume":"7","author":"Grant","year":"1969","journal-title":"Exp. Brain Res."},{"key":"10.1016\/0006-8993(70)90345-8_bib62","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/cne.900230503","article-title":"Studies on the regeneration of the peroneal nerve of the albino rat: number and sectional area of fibers: area relation of axis to sheath","volume":"23","author":"Greenman","year":"1913","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib63","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1152\/physrev.1956.36.4.441","article-title":"Regeneration in the mammalian peripheral nervous system","volume":"36","author":"Guth","year":"1956","journal-title":"Physiol. Rev."},{"key":"10.1016\/0006-8993(70)90345-8_bib64","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1152\/physrev.1968.48.4.645","article-title":"\u2018Trophic\u2019 influences of nerve on muscle","volume":"48","author":"Guth","year":"1968","journal-title":"Physiol. Rev."},{"key":"10.1016\/0006-8993(70)90345-8_bib65","first-page":"72","article-title":"Neurotrophic relations in the regeneration process","volume":"Vol. 13","author":"Gutmann","year":"1964"},{"key":"10.1016\/0006-8993(70)90345-8_bib66","first-page":"493","article-title":"Nervous regulation of nucleic acid level in cross-striated muscle. Changes in denervated muscle","volume":"10","author":"Gutmann","year":"1961","journal-title":"Physiol. bohemoslov."},{"key":"10.1016\/0006-8993(70)90345-8_bib67","first-page":"437","article-title":"Effect of age on proteosynthesis in spinal motoneurones following nerve interruption as shown by histoautoradiography of35S labelled methionine","volume":"11","author":"Gutmann","year":"1962","journal-title":"Physiol. bohemoslov."},{"key":"10.1016\/0006-8993(70)90345-8_bib68","first-page":"192","article-title":"Fine structure of spinal ganglia of the cat","volume":"163","author":"Ha","year":"1969","journal-title":"Anat. Rec."},{"key":"10.1016\/0006-8993(70)90345-8_bib69","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1111\/j.1471-4159.1969.tb08974.x","article-title":"Synthesis of RNA in neurons of the hypoglossal nucleus after section of the axon in mice","volume":"16","author":"Haddad","year":"1969","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib70","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/cne.901080206","article-title":"Behaviour of the accessory body of Cajal during axon reaction","volume":"108","author":"Haggar","year":"1957","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib71","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/cne.900730307","article-title":"Reactions of dorsal root ganglion cells to section of peripheral and central processes","volume":"73","author":"Hare","year":"1940","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib72","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/cne.900670203","article-title":"Reaction of spinal ganglion cells to section of dorsal roots","volume":"67","author":"Hinsey","year":"1937","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib73","first-page":"92","article-title":"Refractoriness of nerve cells to poliomyelitis virus after interruption of their axones","volume":"69","author":"Howe","year":"1941","journal-title":"John Hopk. Hosp. Bull."},{"key":"10.1016\/0006-8993(70)90345-8_bib74","first-page":"39","article-title":"An electron microscopic study of the early changes proximal to a constriction in sympathetic nerves","volume":"172","author":"Kapeller","year":"1969"},{"key":"10.1016\/0006-8993(70)90345-8_bib75","first-page":"53","article-title":"An electron microscopic study of the early changes distal to a constriction in sympathetic nerves","volume":"172","author":"Kapeller","year":"1969"},{"key":"10.1016\/0006-8993(70)90345-8_bib76","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0006-8993(68)90035-8","article-title":"Transport of labelled proteins in the optic nerve and tract of the rabbit","volume":"11","author":"Karlsson","year":"1968","journal-title":"Brain Research"},{"key":"10.1016\/0006-8993(70)90345-8_bib77","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/0006-8993(69)90274-1","article-title":"The effect of colchicine on the axonal transport of protein in the optic nerve and tract of the rabbit","volume":"13","author":"Karlsson","year":"1969","journal-title":"Brain Research"},{"key":"10.1016\/0006-8993(70)90345-8_bib78","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/0010-406X(67)90337-4","article-title":"The transport of labelled material between CNS and muscles along a nerve trunk","volume":"23","author":"Kerkut","year":"1967","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/0006-8993(70)90345-8_bib79","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/cne.901320110","article-title":"Chromatolysis in the hypoglossal nucleus of the rat: an electron microscopic analysis","volume":"132","author":"Kirkpatrick","year":"1968","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib80","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1126\/science.155.3760.342","article-title":"Axonal delivery of neuroplasmic components to muscle","volume":"155","author":"Korr","year":"1967","journal-title":"Science"},{"key":"10.1016\/0006-8993(70)90345-8_bib81","first-page":"722","article-title":"Neuronal dynamics and axonal flow. IV. Blockage of intra-axonal enzyme transport by colchicine","volume":"62","author":"Kreutzberg","year":"1969"},{"key":"10.1016\/0006-8993(70)90345-8_bib82","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1471-4159.1967.tb09522.x","article-title":"Ribonucleic acid content and metabolic activity of lateral geniculate nucleus in monkey following afferent denervation","volume":"14","author":"Kupfer","year":"1967","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib83","first-page":"825","article-title":"Axonal regeneration in the dorsal columns of the spinal cord of adult rats. An electron microscopic study","volume":"13","author":"Lampert","year":"1964","journal-title":"Lab. Invest."},{"key":"10.1016\/0006-8993(70)90345-8_bib84","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/0006-8993(68)90003-6","article-title":"Axoplasmic transport in cat dorsal root ganglion cells as studied withL-[3H]leucine","volume":"7","author":"Lasek","year":"1968","journal-title":"Brain Research"},{"key":"10.1016\/0006-8993(70)90345-8_bib85","first-page":"49","article-title":"Absence of ultrastructural changes in ganglionic neurones after supranodose vagotomy","volume":"104","author":"Lieberman","year":"1969","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib86","first-page":"309","article-title":"Light- and electron-microscope observations on the Golgi apparatus of normal and axotomized primary sensory neurones","volume":"104","author":"Lieberman","year":"1969","journal-title":"J. Anat. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib87","unstructured":"Lieberman, A. R., Axon reaction in vertebrate neurons, a review of some perikaryal responses and associated glial reactions induced by axonal injuries,Int. Rev. Neurobiol., in press."},{"key":"10.1016\/0006-8993(70)90345-8_bib88","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1038\/196837a0","article-title":"Changes in the protein content of the spinal motor neurones of the mouse after severance of the axon","volume":"196","author":"Lison","year":"1962","journal-title":"Nature (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib89","series-title":"Regeneration in the Central Nervous System","first-page":"84","article-title":"Time pattern in retrograde degeneration after trauma of central nervous system of mammals","author":"Liu","year":"1955"},{"key":"10.1016\/0006-8993(70)90345-8_bib90","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/cne.900920204","article-title":"An attempt to produce structural changes in nerve cells by intense functional excitation induced electrically","volume":"92","author":"Liu","year":"1950","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib91","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1111\/j.1471-4159.1968.tb11635.x","article-title":"Proximo-distal transport of [14C]nor-adrenaline and protein in sympathetic nerves","volume":"15","author":"Livett","year":"1968","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib92","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0014-4827(56)90068-4","article-title":"Outflow from cut ends of nerve fibres","volume":"10","author":"Lubinska","year":"1956","journal-title":"Exp. Cell Res."},{"key":"10.1016\/0006-8993(70)90345-8_bib93","first-page":"1","article-title":"Axoplasmic streaming in regenerated and in normal fibres","volume":"Vol. 13","author":"Lubinska","year":"1964"},{"key":"10.1016\/0006-8993(70)90345-8_bib94","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1093\/brain\/86.3.443","article-title":"A quantitative evaluation of hypothalamic degeneration and its relation to diabetes insipidus following interruption of the human hypophyseal stalk","volume":"86","author":"Maccubbin","year":"1963","journal-title":"Brain"},{"key":"10.1016\/0006-8993(70)90345-8_bib95","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1083\/jcb.38.3.494","article-title":"Fast and slow components in axonal transport of protein","volume":"38","author":"McEwen","year":"1968","journal-title":"J. Cell Biol."},{"key":"10.1016\/0006-8993(70)90345-8_bib96","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1085\/jgp.42.5.931","article-title":"Responses of motoneurons undergoing chromatolysis","volume":"42","author":"McIntyre","year":"1959","journal-title":"J. gen. Physiol."},{"key":"10.1016\/0006-8993(70)90345-8_bib97","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1471-4159.1961.tb13500.x","article-title":"Metabolic and chemical changes in regenerating neurones","volume":"7","author":"Miani","year":"1961","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib98","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1960.sp006416","article-title":"The acetylcholine sensitivity of frog muscle fibres after complete or partial denervation","volume":"151","author":"Miledi","year":"1960","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib99","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1002\/cne.900980205","article-title":"Regeneration of sensory spinal nerve roots in young and in senile rats","volume":"98","author":"Moyer","year":"1953","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib100","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/0014-4886(69)90124-1","article-title":"Changes in the morphology and amino acid incorporation of regenerating goldfish optic neurones","volume":"23","author":"Murray","year":"1969","journal-title":"Exp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib101","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1111\/j.1471-4159.1967.tb10310.x","article-title":"Two fractions of axonal acetylcholin-esterase exhibiting different behaviour in severed nerves","volume":"14","author":"Niemierko","year":"1967","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib102","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/cne.900350202","article-title":"On bilateral effects from the unilateral section of branches of the nervus trigeminus in the albino rat","volume":"35","author":"Nittono","year":"1923","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib103","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/0014-4886(61)90070-X","article-title":"Note on the signal for chromatolysis after nerve interruption","volume":"3","author":"Ochs","year":"1961","journal-title":"Exp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib104","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00686605","article-title":"Studies on vascular permeability in peripheral nerves. 1. Distribution of circulating fluorescent serum albumin in normal, crushed and sectioned rat sciatic nerve","volume":"7","author":"Olsson","year":"1966","journal-title":"Acta neuropath. (Berl.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib105","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1093\/brain\/43.3.290","article-title":"Alterations of the Golgi apparatus in nerve cells","volume":"43","author":"Penfield","year":"1920","journal-title":"Brain"},{"key":"10.1016\/0006-8993(70)90345-8_bib106","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/cne.901320206","article-title":"Dorsal root projections to dorsal horn neurones in the cat spinal cord","volume":"132","author":"Ralston","year":"1968","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib107","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/cne.900940209","article-title":"The motor cell columns of the lumbo-sacral spinal cord of the cat","volume":"94","author":"Romanes","year":"1951","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib108","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/cne.900910306","article-title":"The relations of thalamic connections, cellular structure and evocable electrical activity in the auditory region of the cat","volume":"91","author":"Rose","year":"1949","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib109","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1152\/ajplegacy.1939.126.1.39","article-title":"A study of denervated mammalian skeletal muscle","volume":"126","author":"Rosenblueth","year":"1937","journal-title":"Amer. J. Physiol."},{"key":"10.1016\/0006-8993(70)90345-8_bib110","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1126\/science.152.3723.787","article-title":"Regeneration in spinal neurons: proteosynthesis following nerve growth factor administration","volume":"152","author":"Scott","year":"1966","journal-title":"Science"},{"key":"10.1016\/0006-8993(70)90345-8_bib111","first-page":"259","article-title":"Neurofibrillar changes in motor neurons undergoing diffuse versus central chromatolysis: a light and electron microscopic study","volume":"163","author":"Sechrist","year":"1969","journal-title":"Anat. Rec."},{"issue":"Suppl. 270","key":"10.1016\/0006-8993(70)90345-8_bib112","first-page":"1","article-title":"Studies on glial cells in the hypoglossal nucleus of the rabbit during nerve regeneration, and morphological changes in glial cells during nerve regeneration","volume":"67","author":"Sj\u00f6strand","year":"1966","journal-title":"Acta physiol. scand."},{"key":"10.1016\/0006-8993(70)90345-8_bib113","series-title":"Neurosecretion","article-title":"Pathological aspects of the concept of neurosecretion with special reference to the pathogenesis of diabetes insipidus","author":"Sloper","year":"1967"},{"key":"10.1016\/0006-8993(70)90345-8_bib114","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1159\/000142874","article-title":"Spinal ganglion cytological responses to axon and to dendrite sectioning","volume":"65","author":"Sosa","year":"1966","journal-title":"Acta anat. (Basel)"},{"key":"10.1016\/0006-8993(70)90345-8_bib115","first-page":"585","article-title":"The naso-temporal division of the cat's retina","volume":"126","author":"Stone","year":"1966","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib116","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1113\/jphysiol.1960.sp006463","article-title":"Supersensitivity of skeletal muscle produced by botulinum toxin","volume":"151","author":"Thesleff","year":"1960","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib117","first-page":"69P","article-title":"The influence of repeated crush injuries on the nuclear population of peripheral nerve","volume":"201","author":"Thomas","year":"1969","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib118","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/cne.900590203","article-title":"The relation of taste buds to their nerve fibres","volume":"59","author":"Torrey","year":"1934","journal-title":"J. comp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib119","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/BF00691440","article-title":"Histological studies on the effect of actinomycin D on retrograde nerve cell reaction in the facial nucleus of mice","volume":"9","author":"Torvik","year":"1967","journal-title":"Acta neuropath. (Berl.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib120","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/brain\/54.1.99","article-title":"A search for a trophic influence of posterior spinal roots on skeletal muscle, with a note on the nerve fibres found in the proximal stump of the roots after excision of the root ganglion","volume":"54","author":"Tower","year":"1931","journal-title":"Brain"},{"key":"10.1016\/0006-8993(70)90345-8_bib121","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1001\/archneurpsyc.1940.02280120084008","article-title":"Gef\u00e4ssver\u00e4nderungen in den Thalamuskernen bei retrograder Degeneration","volume":"44","author":"Tsang","year":"1940","journal-title":"Arch. Neurol. Psychiat. (Chic.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib122","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/00005072-196101000-00003","article-title":"Experimental study of diphtheritic polyneuritis in the rabbit and guinea pig. III. The blood-nerve barrier in the rabbit","volume":"20","author":"Waksman","year":"1961","journal-title":"J. Neuropath. exp. Neurol."},{"key":"10.1016\/0006-8993(70)90345-8_bib123","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1113\/jphysiol.1965.sp007728","article-title":"An autoradiographic study of the incorporation of nucleic acid precursors by neurones and glia during nerve regeneration","volume":"180","author":"Watson","year":"1965","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib124","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1113\/jphysiol.1965.sp007729","article-title":"An autoradiographic study of the incorporation of nucleic acid precursors by neurones and glia during nerve stimulation","volume":"180","author":"Watson","year":"1965","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib125","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/j.1471-4159.1966.tb09869.x","article-title":"Alteration of the adherence of glia to neurons following nerve injury","volume":"13","author":"Watson","year":"1966","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib126","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/j.1471-4159.1966.tb05880.x","article-title":"Some quantitative observations upon the oxidation of substrates of the tricarboxylic acid cycle in injured neurons","volume":"13","author":"Watson","year":"1966","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib127","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1111\/j.1471-4159.1966.tb04322.x","article-title":"Quantitative observations upon acetylcholine hydrolase activity of nerve cells after axotomy","volume":"13","author":"Watson","year":"1966","journal-title":"J. Neurochem."},{"key":"10.1016\/0006-8993(70)90345-8_bib128","first-page":"122","article-title":"Centripetal passage of labelled molecules along mammalian motor axons","volume":"196","author":"Watson","year":"1968","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib129","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1113\/jphysiol.1968.sp008528","article-title":"Observations on the nucleolar and total cell body nucleic acid of injured nerve cells","volume":"196","author":"Watson","year":"1968","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib130","first-page":"77","article-title":"Anaerobic glycolytic capacity of nerve cells after axotomy","volume":"198","author":"Watson","year":"1968","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib131","first-page":"80","article-title":"The change in dry mass of hypoglossal neurones induced by puromycin, and the effects of nerve injury","volume":"201","author":"Watson","year":"1969","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib132","doi-asserted-by":"crossref","first-page":"101P","DOI":"10.1113\/jphysiol.1969.sp008830","article-title":"The response of rat hypoglossal neurones to injection of botulinum toxin into the tongue","volume":"202","author":"Watson","year":"1969","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib133","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1113\/jphysiol.1969.sp008830","article-title":"The response of motor neurones to intramuscular injection of botulinum toxin","volume":"202","author":"Watson","year":"1969","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib134","first-page":"138P","article-title":"Some metabolic responses of motor neurones to axotomy and to botulinum toxin after nerve transplantation","volume":"204","author":"Watson","year":"1969","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1016\/0006-8993(70)90345-8_bib135","first-page":"1239","article-title":"Neuronal dynamics and axonal flow. III. Cellulifugal transport of labelled neuroplasm in isolated nerve preparations","volume":"57","author":"Weiss","year":"1967"},{"key":"10.1016\/0006-8993(70)90345-8_bib136","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/ar.1090920304","article-title":"The effect of terminal connections on the caliber of nerve fibers","volume":"92","author":"Weiss","year":"1945","journal-title":"Anat. Rec."},{"key":"10.1016\/0006-8993(70)90345-8_bib137","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1126\/science.136.3513.330","article-title":"The nerve fiber as a system in continuous flow: microcinematographic and electron microscopic demonstrations","volume":"136","author":"Weiss","year":"1962","journal-title":"Science"},{"key":"10.1016\/0006-8993(70)90345-8_bib138","first-page":"48","article-title":"Convection and fate of mitochondria in nerve fibers: axonal flow as a vehicle","volume":"54","author":"Weiss","year":"1965"},{"key":"10.1016\/0006-8993(70)90345-8_bib139","series-title":"Growth of the Nervous System, CIBA Foundation Symposium","first-page":"245","year":"1968"}],"container-title":["Brain Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0006899370903458?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0006899370903458?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T13:00:26Z","timestamp":1734008426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0006899370903458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,9]]},"references-count":139,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1970,9]]}},"alternative-id":["0006899370903458"],"URL":"https:\/\/doi.org\/10.1016\/0006-8993(70)90345-8","relation":{},"ISSN":["0006-8993"],"issn-type":[{"value":"0006-8993","type":"print"}],"subject":[],"published":{"date-parts":[[1970,9]]}}}