{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T04:57:54Z","timestamp":1779339474398,"version":"3.51.4"},"reference-count":47,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1992,1,1]],"date-time":"1992-01-01T00:00:00Z","timestamp":694224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1992,1,1]],"date-time":"1992-01-01T00:00:00Z","timestamp":694224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[1992,1]]},"DOI":"10.1016\/0012-1606(92)90270-q","type":"journal-article","created":{"date-parts":[[2004,12,16]],"date-time":"2004-12-16T08:07:07Z","timestamp":1103184427000},"page":"134-148","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":435,"title":["Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster"],"prefix":"10.1016","volume":"149","author":[{"given":"Kei","family":"Ito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Hotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0012-1606(92)90270-Q_BIB1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1432-0436.1986.tb00392.x","article-title":"Differentiation of TERA-2 human embryonal carcinoma cells into neurons and HCMV permissive cells","volume":"31","author":"Andrews","year":"1986","journal-title":"Differentiation"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB2","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1093\/nar\/16.6.2411","article-title":"The promoter of the chicken cardiac myosin light chain 2 gene shows cell-specific expression in transfected primary cultures of chicken muscle","volume":"16","author":"Arnold","year":"1988","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB3","first-page":"57","article-title":"Staging the metamorphosis of Drosophila melanogaster","volume":"66","author":"Bainbridge","year":"1981","journal-title":"J. Embryol. Exp. Morphol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/01677068709167218","article-title":"Are the structural changes in adult Drosophila mushroom bodies memory traces?","volume":"4","author":"Balling","year":"1987","journal-title":"J. Neurogenetics"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0165-3806(87)90020-4","article-title":"Autoradiographic analysis of effects of 5-bromodeoxyuridine on neurogenesis in the chick embryo spinal cord","volume":"433","author":"Bannigan","year":"1987","journal-title":"Brain. Res"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB6","first-page":"107","article-title":"Embryogenesis of an insect nervous system. I. A map of the thoracic and abdominal neuroblasts in Locusta migratoria","volume":"35","author":"Bate","year":"1976","journal-title":"J. Embryol. Exp. Morphol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB7","first-page":"123","article-title":"Zur inneren Metamorphose des Zentralnervensystems der Insekten","volume":"20","author":"Bauer","year":"1904","journal-title":"Zool. Jhb. Anat. Ontog. Tiere"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB8","first-page":"413","article-title":"Some modifications of Holmes's silver method for insect central nervous system","volume":"102","author":"Blest","year":"1961","journal-title":"Q. J. Microscop. Sci"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB9","series-title":"Biology of Drosophila","first-page":"420","article-title":"The postembryonic development of Drosophila","author":"Bodenstein","year":"1950"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB10","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0896-6273(89)90112-8","article-title":"Neurogenesis of the peripheral nervous system in Drosophila embryos: DNA replication patterns and cell lineages","volume":"3","author":"Bodmer","year":"1989","journal-title":"Neuron"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB11","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1182\/blood.V68.5.1036.1036","article-title":"Bromodeoxyuridine treatment of normal adult erythroid colonies: An in vitro model for reactivation of human fetal globin genes","volume":"68","author":"Comi","year":"1986","journal-title":"Blood"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1432-0436.1987.tb00147.x","article-title":"The mouse Hox2.3 homeobox-containing gene: Regulation in differentiating pluripotent stem cells and expression pattern in embryos","volume":"35","author":"Deschamps","year":"1987","journal-title":"Differentiation"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB13","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/0092-8674(90)90012-4","article-title":"The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string","volume":"62","author":"Edgar","year":"1990","journal-title":"Cell"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB14","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0065-2806(08)60111-3","article-title":"Postembryonic development and regeneration of the insect nervous system","volume":"6","author":"Edwards","year":"1969","journal-title":"Adv. Insect Physiol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB15","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0012-1606(85)90419-1","article-title":"Cell division cycle of cultured neural precursor cells from Drosophila","volume":"112","author":"Furst","year":"1985","journal-title":"Dev. Biol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB16","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1126\/science.7123245","article-title":"Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication","volume":"218","author":"Gratzner","year":"1982","journal-title":"Science"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB17","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/BF00848159","article-title":"Early neurogenesis in wild-type Drosophila melanogaster","volume":"193","author":"Hartenstein","year":"1984","journal-title":"Roux's Arch. Dev. Biol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB18","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/BF00399871","article-title":"The pattern of proliferation of the neuroblasts in the wild-type embryo of Drosophila melanogaster","volume":"196","author":"Hartenstein","year":"1987","journal-title":"Roux's Arch. Dev. Biol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB19","series-title":"Development and Neurobiology of Drosophila","first-page":"373","article-title":"Mutants of brain structure and function: what is the significance of the mushroom bodies for behavior?","author":"Heisenberg","year":"1980"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB20","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00407351","article-title":"Das relative postembryonale Wachstum der Hirnteile von Culex pipiens, Drosophila melanogaster und Drosophila-mutanten","volume":"50","author":"Hinke","year":"1961","journal-title":"Z. Morph. \u00d6kol. Tiere"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB21","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/BF00377393","article-title":"Proliferation pattern and early differentiation of the optic lobes in Drosophila melanogaster","volume":"198","author":"Hofbauer","year":"1990","journal-title":"Roux's Arch. Dev. Biol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB22","first-page":"295","article-title":"The structure and development of the nervous system","volume":"Vol. 2d","author":"Kankel","year":"1980"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB23","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1523\/JNEUROSCI.10-02-00403.1990","article-title":"Postmetamorphic cell death in the nervous and muscular systems of Drosophila melanogaster","volume":"10","author":"Kimura","year":"1990","journal-title":"J. Neurosci"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB24","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/0014-4827(90)90274-E","article-title":"Effect of thymidine analogs on tyrosinase activity and mRNA accumulation in mouse melanoma cells","volume":"188","author":"Kidson","year":"1990","journal-title":"Exp. Cell Res"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB25","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1101\/gad.3.7.986","article-title":"An avian muscle factor related to MyoD1 activates muscle-specific promoters in nonmuscle cells of different germ-layer origin and in BrdU-treated myoblasts","volume":"3","author":"Lin","year":"1989","journal-title":"Genes Dev"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB26","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/0006-8993(88)90055-8","article-title":"Use of bromodeoxyuridine immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system","volume":"457","author":"Miller","year":"1988","journal-title":"Brain. Res"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB27_1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/BF00576929","article-title":"Postembryonic brain development in the monarch butterfly Danaus plexippus plexippus, L. I and II","volume":"162","author":"Nordlander","year":"1969","journal-title":"Wilhelm Roux' Archiv. Dev. Biol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB27_2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/BF00573531","article-title":"Postembryonic brain development in the monarch butterfly Danaus plexippus plexippus, L. I and II","volume":"163","author":"Nordlander","year":"1969","journal-title":"Wilhelm Roux' Archiv. Dev. Biol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB28","first-page":"269","article-title":"The structure of the brain in insects in successive stages of postembryonic development","volume":"36","author":"Panov","year":"1957","journal-title":"Entomol. Obozrenie"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB29","first-page":"179","article-title":"Correlations in the ontogenetic development of the central nervous system in the house cricket Gryllus domestics L., and the mole cricket Gryllotalpa gryllotalpa (Orthoptera, Grylloidea)","volume":"45","author":"Panov","year":"1966","journal-title":"Entomol. Obozrenie"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB30","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1242\/dev.103.4.791","article-title":"Proliferation kinetics and cell lineages can be studied in whole mounts and macerates by means of BrdU\/anti-BrdU technique","volume":"103","author":"Plickert","year":"1988","journal-title":"Development"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB31","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/jmor.1050910302","article-title":"A quantitative study of the growth of the central nervous system of a holometabolous insect, Drosophila melanogaster","volume":"91","author":"Power","year":"1952","journal-title":"J. Morphol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB32","series-title":"Synapse, Transmission, Modulation; Proceedings of the 19th G\u00f6ttingen Neurobiology Conference","article-title":"The mushroom body defect gene affects proliferation behavior of postembryonic neuroblasts","author":"Prokop","year":"1991"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1242\/dev.111.1.79","article-title":"The origin of postembryonic neuroblasts in the ventral nerve cord of Drosophila melanogaster","volume":"111","author":"Prokop","year":"1991","journal-title":"Development"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB34","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1139\/g87-028","article-title":"Analysis of low concentrations of 5-bromo-2-deoxyuridine on sister chromatid exchanges in human lymphocytes","volume":"29","author":"Richer","year":"1987","journal-title":"Genome"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB35","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1242\/dev.108.1.83","article-title":"Spatial and temporal patterns of neurogenesis in the embryo of the locust (Schistocerca gregaria)","volume":"108","author":"Shepherd","year":"1990","journal-title":"Development"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB36","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF00327741","article-title":"Neuronal architecture of the antennal lobe in Drosophila melanogaster","volume":"262","author":"Stocker","year":"1990","journal-title":"Cell Tissue Res"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB37","series-title":"Atlas of an Insect Brain","author":"Strausfeld","year":"1976"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB38","first-page":"2531","article-title":"Schwannian cell differentiation of human neuroblastoma cell lines in vitro induced by bromodeoxyuridine","volume":"48","author":"Sugimoto","year":"1988","journal-title":"Cancer Res"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB39","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1126\/science.2547249","article-title":"5-bromo-2\u2032-deoxyuridine blocks myogenesis by extinguishing expression of MyoD1","volume":"245","author":"Tapscott","year":"1989","journal-title":"Science"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB40","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3109\/01677068409107077","article-title":"Fiber number in the mushroom bodies of adult Drosophila melanogaster depends on age, sex, and experience","volume":"1","author":"Technau","year":"1984","journal-title":"J. Neurogenet"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB41","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/295405a0","article-title":"Neural reorganization during metamorphosis of the corpora pedunculata in Drosophila melanogaster","volume":"295","author":"Technau","year":"1982","journal-title":"Nature"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB42","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1440-169X.1988.00261.x","article-title":"The cell cycle and cell population kinetics in the programmed cell death in the limb-buds of normal and 5-bromodeoxyuridine-treated chick embryos","volume":"30","author":"Ton\u00e9","year":"1988","journal-title":"Dev. Growth Differ"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB43","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1002\/neu.480210711","article-title":"Metamorphosis of the central nervous system of Drosophila","volume":"21","author":"Truman","year":"1990","journal-title":"J. Neurobiol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB44","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0012-1606(88)90067-X","article-title":"Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogaster","volume":"125","author":"Truman","year":"1988","journal-title":"Dev. Biol"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB45","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0165-7992(88)90114-5","article-title":"Cytotoxic and genotoxic effects of bromodeoxyuridine during in vitro labelling for sister-chromatid differentiation in preimplantation mouse embryos","volume":"209","author":"Vogel","year":"1988","journal-title":"Mutat. Res"},{"key":"10.1016\/0012-1606(92)90270-Q_BIB46","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/0012-1606(78)90029-5","article-title":"Patterns of cell division and cell movement in the formation of the imaginal nervous system in Drosophila melanogaster","volume":"65","author":"White","year":"1978","journal-title":"Dev. Biol"}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:001216069290270Q?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:001216069290270Q?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T06:59:46Z","timestamp":1762066786000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/001216069290270Q"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,1]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1992,1]]}},"alternative-id":["001216069290270Q"],"URL":"https:\/\/doi.org\/10.1016\/0012-1606(92)90270-q","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[1992,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/0012-1606(92)90270-Q","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1992 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}