{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:45:42Z","timestamp":1761763542549},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2001,11,2]],"date-time":"2001-11-02T00:00:00Z","timestamp":1004659200000},"content-version":"vor","delay-in-days":6416,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[1984,4,9]]},"abstract":"<jats:p>Heparin inhibited the dephosphorylation of rabbit skeletal muscle or liver phosphorylase <jats:italic>a<\/jats:italic> by protein phosphatase\u20101. Other glycosaminoglycans (chondroitin sulfates) and their constituents were found to be without effect. The chromatography of a partially purified phosphatase preparation on heparin\u2014Sepharose CL\u20106B resulted in a fraction that did not bind to the matrix and its activity was not inhibited by heparin or inhibitor\u20101. The phosphatase bound to heparin\u2014Sepharose was eluted by 0.2 M NaCl and was inhibited by heparin or inhibitor\u20101.<\/jats:p>","DOI":"10.1016\/0014-5793(84)80286-0","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T07:59:22Z","timestamp":1027583962000},"page":"45-48","source":"Crossref","is-referenced-by-count":54,"title":["Heparin inhibits the activity of protein phosphatase\u20101"],"prefix":"10.1002","volume":"169","author":[{"given":"P\u00e1l","family":"Gergely","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Erd\u0151di","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Bot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,11,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/296613a0"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6306765"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.48.070179.004423"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.49.070180.004121"},{"key":"e_1_2_1_6_1","first-page":"163","volume":"16","author":"Gergely P.","year":"1981","journal-title":"Acta Biochim. Biophys. Acad. Sci. Hung."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(83)91073-2"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1978.tb12384.x"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1983.tb07485.x"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1983.tb07363.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-152821-8.50009-8"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(82)90506-9"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00896a003"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)42993-6"},{"key":"e_1_2_1_15_1","author":"Erd\u0151di F.","year":"1984","journal-title":"Int. J. Biochem."},{"key":"e_1_2_1_16_1","first-page":"425","volume":"8","author":"Lee E.Y.C.","year":"1981","journal-title":"Cold Spring Harbor Conf. Cell Proliferation"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)40812-0"},{"key":"e_1_2_1_18_1","first-page":"183","volume":"17","author":"Bot G.","year":"1982","journal-title":"Biochim. Biophys. Acad. Sci. Hung."},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1982.tb05904.x"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(82)81010-7"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793%2884%2980286-0","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793(84)80286-0","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/0014-5793%2884%2980286-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T08:17:55Z","timestamp":1694852275000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1016\/0014-5793%2884%2980286-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,4,9]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1984,4,9]]}},"alternative-id":["10.1016\/0014-5793(84)80286-0"],"URL":"https:\/\/doi.org\/10.1016\/0014-5793(84)80286-0","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,4,9]]}}}