{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T20:52:40Z","timestamp":1771015960513,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1993,9,1]],"date-time":"1993-09-01T00:00:00Z","timestamp":746841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1993,9,1]],"date-time":"1993-09-01T00:00:00Z","timestamp":746841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000406","name":"Motor Neurone Disease Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000406","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jns-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Neurological Sciences"],"published-print":{"date-parts":[[1993,9]]},"DOI":"10.1016\/0022-510x(93)90111-b","type":"journal-article","created":{"date-parts":[[2003,4,24]],"date-time":"2003-04-24T22:41:48Z","timestamp":1051224108000},"page":"202-206","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Expression of the human groEL stress-protein homologue in the brain and spinal cord"],"prefix":"10.1016","volume":"118","author":[{"given":"J.E.","family":"Martin","sequence":"first","affiliation":[]},{"given":"M.","family":"Swash","sequence":"additional","affiliation":[]},{"given":"K.","family":"Mather","sequence":"additional","affiliation":[]},{"given":"P.N.","family":"Leigh","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/0022-510X(93)90111-B_BIB1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0092-8674(79)90150-8","article-title":"The induction of gene activity in Drosophila by heat shock","volume":"17","author":"Ashburner","year":"1979","journal-title":"Cell"},{"key":"10.1016\/0022-510X(93)90111-B_BIB2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/349205a0","article-title":"Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria","volume":"349","author":"Baker","year":"1991","journal-title":"Nature"},{"key":"10.1016\/0022-510X(93)90111-B_BIB3","first-page":"848","article-title":"Major heat shock gene of Drosophila and the Escherichia coli inducible dnaK gene are homologous","volume":"81","author":"Bardwell","year":"1984"},{"key":"10.1016\/0022-510X(93)90111-B_BIB4","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1750-3639.1992.tb00679.x","article-title":"New morphological approaches to the study of mitochondrial encephalomyopathies","volume":"2","author":"Bonilla","year":"1992","journal-title":"Brain Pathol."},{"key":"10.1016\/0022-510X(93)90111-B_BIB5","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/337620a0","article-title":"Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria","volume":"337","author":"Cheng","year":"1989","journal-title":"Nature"},{"key":"10.1016\/0022-510X(93)90111-B_BIB6","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1038\/332800a0","article-title":"A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides","volume":"332","author":"Deshaies","year":"1988","journal-title":"Nature"},{"key":"10.1016\/0022-510X(93)90111-B_BIB7","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1699-0463.1990.tb01055.x","article-title":"Distribution in tissue sections of the human groEL stress-protein homologue","volume":"98","author":"Evans","year":"1990","journal-title":"APMIS"},{"key":"10.1016\/0022-510X(93)90111-B_BIB8","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0968-0004(85)90108-2","article-title":"The ubiquitin system: functions and mechanisms","author":"Finley","year":"1985","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/0022-510X(93)90111-B_BIB9","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/333330a0","article-title":"Homologous plant and bacterial proteins chaparone oligomeric protein assembly","volume":"333","author":"Hemmingsen","year":"1988","journal-title":"Nature"},{"key":"10.1016\/0022-510X(93)90111-B_BIB10","first-page":"528","article-title":"Definition of species specific and cross-reactive antigenic determinants of Mycobacterium leprae using monoclonal antibodies","volume":"52","author":"Ivanyi","year":"1983","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/0022-510X(93)90111-B_BIB11","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0167-5699(90)90050-J","article-title":"Heat shock proteins and the immune response","volume":"11","author":"Kaufmann","year":"1990","journal-title":"Immunol. Today"},{"key":"10.1016\/0022-510X(93)90111-B_BIB12","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0304-3940(88)90081-X","article-title":"Ubiquitin deposits in anterior horn cells in motor neuron disease","volume":"93","author":"Leigh","year":"1988","journal-title":"Neurosci. Lett."},{"key":"10.1016\/0022-510X(93)90111-B_BIB13","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1146\/annurev.ge.22.120188.003215","article-title":"The heat shock proteins","volume":"22","author":"Lindquist","year":"1988","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/0022-510X(93)90111-B_BIB14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/path.1711550105","volume":"155","author":"Lowe","year":"1988","journal-title":"J. Pathol."},{"key":"10.1016\/0022-510X(93)90111-B_BIB15","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1365-2990.1991.tb00702.x","article-title":"Heat shock protein expression in corpora amylacea in the central nervous system: clues to their origin","volume":"17","author":"Martin","year":"1991","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/0022-510X(93)90111-B_BIB16","first-page":"4414","article-title":"A normal mitochondrial protein is selectively synthesised and accumulated during heat shock in Tetrahymena thermophila","volume":"7","author":"McMullin","year":"1987","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/0022-510X(93)90111-B_BIB17","first-page":"371","article-title":"A highly evolutionarily conserved mitochondrial protein is structurally related to the protein encoded by the Escherichia coil groEL gene","volume":"8","author":"McMullin","year":"1988","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/0022-510X(93)90111-B_BIB18","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1038\/332776a0","article-title":"Heat shock proteins","volume":"332","author":"Pelham","year":"1988","journal-title":"Nature"},{"key":"10.1016\/0022-510X(93)90111-B_BIB19","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/0092-8674(86)90693-8","article-title":"Speculations on the functions of the major heat shock and glucose-regulated proteins","volume":"46","author":"Pelham","year":"1986","journal-title":"Cell"},{"key":"10.1016\/0022-510X(93)90111-B_BIB20","first-page":"478","article-title":"Synovial fluid T cell reactivity against 65 kDa heat shock protein of mycobacteria in early chronic arthritis","volume":"ii","author":"Rase","year":"1988","journal-title":"Lancet"},{"key":"10.1016\/0022-510X(93)90111-B_BIB21","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1128\/iai.56.2.446-451.1988","article-title":"The Mycobacterium tuberculosIs 65-kilodalton antigen is a heat shock protein which corresponds to common antigen and to the Escherichia coli Gro EL protein","volume":"56","author":"Shinnick","year":"1988","journal-title":"Infect. Immunol."},{"key":"10.1016\/0022-510X(93)90111-B_BIB22","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1136\/ard.48.2.118","article-title":"Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis","volume":"48","author":"Tsoulfa","year":"1989","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/0022-510X(93)90111-B_BIB23","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/331171a0","article-title":"Cloning of the mycobacterial epitope recognised by T cells in adjuvant arthritis","volume":"331","author":"Van Eden","year":"1988","journal-title":"Nature"},{"key":"10.1016\/0022-510X(93)90111-B_BIB24","series-title":"Immunocytochemistry","first-page":"45","author":"Van Noorden","year":"1986"},{"key":"10.1016\/0022-510X(93)90111-B_BIB25","first-page":"4267","article-title":"Stress proteins are immune targets in leprosy and tuberculosis","volume":"85","author":"Young","year":"1988"}],"container-title":["Journal of the Neurological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0022510X9390111B?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0022510X9390111B?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T10:26:40Z","timestamp":1757327200000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0022510X9390111B"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,9]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1993,9]]}},"alternative-id":["0022510X9390111B"],"URL":"https:\/\/doi.org\/10.1016\/0022-510x(93)90111-b","relation":{},"ISSN":["0022-510X"],"issn-type":[{"value":"0022-510X","type":"print"}],"subject":[],"published":{"date-parts":[[1993,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression of the human groEL stress-protein homologue in the brain and spinal cord","name":"articletitle","label":"Article Title"},{"value":"Journal of the Neurological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/0022-510X(93)90111-B","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1993 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}