{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T13:48:48Z","timestamp":1772804928965,"version":"3.50.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1981,10,1]],"date-time":"1981-10-01T00:00:00Z","timestamp":370742400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[1981,10]]},"DOI":"10.1016\/0090-8258(81)90076-7","type":"journal-article","created":{"date-parts":[[2004,4,18]],"date-time":"2004-04-18T10:05:08Z","timestamp":1082282708000},"page":"S220-S231","source":"Crossref","is-referenced-by-count":135,"special_numbering":"P2","title":["Definition of precursors"],"prefix":"10.1016","volume":"12","author":[{"given":"Yao S.","family":"Fu","sequence":"first","affiliation":[]},{"given":"James W.","family":"Reagan","sequence":"additional","affiliation":[]},{"given":"Ralph M.","family":"Richart","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/0090-8258(81)90076-7_BIB1","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/j.1749-6632.1962.tb34677.x","article-title":"Dysplasia: A basic reaction to injury in the uterine cervix","volume":"97","author":"Reagan","year":"1962","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/0090-8258(81)90076-7_BIB2_1","first-page":"138","author":"Patten","year":"1978"},{"key":"10.1016\/0090-8258(81)90076-7_BIB2_2","first-page":"184","author":"Patten","year":"1978"},{"key":"10.1016\/0090-8258(81)90076-7_BIB3","series-title":"Pathology annual","first-page":"301","article-title":"Cervical intraepithelial neoplasia","author":"Richart","year":"1973"},{"key":"10.1016\/0090-8258(81)90076-7_BIB4","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1002\/1097-0142(196611)19:11<1635::AID-CNCR2820191130>3.0.CO;2-1","article-title":"Influence of diagnostic and therapeutic procedures in the distribution of cervical intraepithelial neoplasia","volume":"19","author":"Richart","year":"1967","journal-title":"Cancer"},{"key":"10.1016\/0090-8258(81)90076-7_BIB5","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1097\/00006254-196907001-00014","article-title":"Concepts of genesis and development in early cervical neoplasia","volume":"24","author":"Christopherson","year":"1969","journal-title":"Obstet. Gynecol. Surv."},{"key":"10.1016\/0090-8258(81)90076-7_BIB6","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/0002-9378(68)90377-3","article-title":"The value of the assay of chromosomes in the diagnosis of cervical neoplasia","volume":"102","author":"Jones","year":"1968","journal-title":"Amer. J. Obstet. Gynecol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB7","series-title":"Chromosomesand cancer","first-page":"423","article-title":"Cytogenetics of cancer and precancerous states of the cervix uteri","author":"Sprigg","year":"1974"},{"key":"10.1016\/0090-8258(81)90076-7_BIB8","first-page":"129","article-title":"Nuclear DNA study of vaginal and cervical squamous cell abnormalities in DES-exposed progeny","volume":"52","author":"Fu","year":"1978","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB9","first-page":"502","article-title":"Nuclear DNA and histologic studies of genital lesions in DES-exposed progeny. I. Intraepithelial squamous abnormalities","volume":"72","author":"Fu","year":"1979","journal-title":"Amer. J. Clin. Pathol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB10","first-page":"233","article-title":"Nuclear DNA characteristics of microinvasive squamous carcinoma of the uterine cervix","volume":"Vol. 1","author":"Fu","year":"1980"},{"key":"10.1016\/0090-8258(81)90076-7_BIB11","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1093\/jnci\/60.6.1251","article-title":"Correction of the modal DNA values obtained by microspectrophotometry and tests for their shifts","volume":"60","author":"Okagaki","year":"1978","journal-title":"J. Nat. Cancer Inst."},{"key":"10.1016\/0090-8258(81)90076-7_BIB12","series-title":"Chromosomes and cancer","first-page":"239","article-title":"Mitotic abnormalities and cancer","author":"Oksala","year":"1974"},{"key":"10.1016\/0090-8258(81)90076-7_BIB13","first-page":"475","article-title":"Polyploidy in the human endometrium with the Arias-Stella reaction","volume":"85","author":"Wagner","year":"1968","journal-title":"Arch. Pathol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB14","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/0002-9378(70)90229-2","article-title":"Nuclear DNA content of lutenized cells of the human ovary","volume":"108","author":"Stangel","year":"1970","journal-title":"Amer. J. Obstet. Gynecol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB15","first-page":"151","article-title":"DNA in human tumors: A cytophotometric study","volume":"60","author":"B\u00f6hm","year":"1975","journal-title":"Curr. Top. Pathol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB16","first-page":"53","article-title":"Electron microscope detection of papilloma virus particles in selected koilocytotic cells in a routine cervical smear","volume":"23","author":"Hills","year":"1979","journal-title":"Acta Cytol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB17","first-page":"476","article-title":"Noncondylomatous cervical wart virus infection","volume":"55","author":"Reid","year":"1980","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB18","first-page":"7","article-title":"Human papilloma virus infection of the cervix","volume":"25","author":"Meisels","year":"1981","journal-title":"Acta Cytol."},{"key":"10.1016\/0090-8258(81)90076-7_BIB19","series-title":"The cervix","first-page":"385","article-title":"Chromosomal changes in cervical neoplasia","author":"Atkin","year":"1976"},{"key":"10.1016\/0090-8258(81)90076-7_BIB20","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1097\/00006254-196907001-00010","article-title":"The study of chromosomes in cervical neoplasia","volume":"24","author":"Kirkland","year":"1969","journal-title":"Obstet. Gynecol. Surv."},{"key":"10.1016\/0090-8258(81)90076-7_BIB21","first-page":"125","article-title":"The evolution of chromosomal aneuploidy in cervical atypia, carcinoma in situ and invasive carcinoma of the uterine cervix","volume":"127","author":"Jones","year":"1970","journal-title":"Johns Hopkins Med. J."}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0090825881900767?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0090825881900767?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T20:28:14Z","timestamp":1550003294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0090825881900767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,10]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1981,10]]}},"alternative-id":["0090825881900767"],"URL":"https:\/\/doi.org\/10.1016\/0090-8258(81)90076-7","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[1981,10]]}}}