{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:21:13Z","timestamp":1779344473101,"version":"3.51.4"},"reference-count":38,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1995,9,1]],"date-time":"1995-09-01T00:00:00Z","timestamp":809913600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":6529,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell"],"published-print":{"date-parts":[[1995,9]]},"DOI":"10.1016\/0092-8674(95)90468-9","type":"journal-article","created":{"date-parts":[[2004,7,21]],"date-time":"2004-07-21T17:57:43Z","timestamp":1090432663000},"page":"709-719","source":"Crossref","is-referenced-by-count":290,"title":["High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA"],"prefix":"10.1016","volume":"82","author":[{"given":"David S","family":"Wilson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Guenther","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claude","family":"Desplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Kuriyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0092-8674(95)90468-9_BIB1","doi-asserted-by":"crossref","first-page":"9187","DOI":"10.1021\/bi00197a022","article-title":"Differential DNA-binding specificity of the engrailed homeodomain: the role of residue 50","volume":"33","author":"Ades","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/0092-8674(95)90468-9_BIB2","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1006\/jmbi.1993.1661","article-title":"Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex","volume":"234","author":"Billeter","year":"1993","journal-title":"J. Mol. Biol."},{"key":"10.1016\/0092-8674(95)90468-9_BIB3","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/0092-8674(86)90818-4","article-title":"Conservation of a large protein domain in the segmentation gene paired and in functionally related genes in Drosophila","volume":"47","author":"Bopp","year":"1986","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB4","first-page":"24","article-title":"Assessment of phase accuracy by cross validation: the free R value","volume":"D49","author":"Br\u00fcnger","year":"1993","journal-title":"Acta Crystallogr."},{"key":"10.1016\/0092-8674(95)90468-9_BIB5","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1107\/S0108767390002355","article-title":"Slow-cooling protocols far crystallographic refinement by simulated annealing","volume":"A46","author":"Br\u00fcnger","year":"1990","journal-title":"Acta Crystallogr."},{"key":"10.1016\/0092-8674(95)90468-9_BIB6","article-title":"The evolution of homeobox genes","volume":"10","author":"B\u00fcrglin","year":"1995"},{"key":"10.1016\/0092-8674(95)90468-9_BIB7","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1128\/MCB.15.5.2858","article-title":"DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5)","volume":"15","author":"Czerny","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/0092-8674(95)90468-9_BIB8","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1107\/S0108767391001071","article-title":"Accurate bond and angle parameters for X-ray protein structure refinement","volume":"A47","author":"Engh","year":"1991","journal-title":"Acta Crystallogr."},{"key":"10.1016\/0092-8674(95)90468-9_BIB9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/363038a0","article-title":"Recognition by Max of its cognate DNA through a dimeric b\/HLH\/Z domain","volume":"363","author":"Ferr\u00e9-D'Amar\u00e9","year":"1993","journal-title":"Nature"},{"key":"10.1016\/0092-8674(95)90468-9_BIB10","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1101\/gad.4.3.444","article-title":"Analysis of cis-acting requirements of the Rh3 and Rh4 genes reveals a bipartite organization to rhodopsin promoters in Drosophila melanogaster","volume":"4","author":"Fortini","year":"1990","journal-title":"Genes Dev."},{"key":"10.1016\/0092-8674(95)90468-9_BIB11","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0092-8674(94)90292-5","article-title":"Homeodomain-DNA recognition","volume":"78","author":"Gehring","year":"1994","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB12","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1126\/science.7892602","article-title":"Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila","volume":"267","author":"Halder","year":"1995","journal-title":"Science"},{"key":"10.1016\/0092-8674(95)90468-9_BIB13","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/0092-8674(90)90492-W","article-title":"What determines the specificity of action of Drosophila homeodomain proteins?","volume":"63","author":"Hayashi","year":"1990","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB14","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1107\/S0108767392006044","article-title":"Model bias in macromolecular structures","volume":"A48","author":"Hodel","year":"1992","journal-title":"Acta Crystallogr."},{"key":"10.1016\/0092-8674(95)90468-9_BIB15","first-page":"1008","article-title":"Twenty Drosophila visual system cDNA clones: one is a homolog of human arrestin","volume":"87","author":"Hyde","year":"1990"},{"key":"10.1016\/0092-8674(95)90468-9_BIB16","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1107\/S0108767390010224","article-title":"Improved methods for building protein models in electron density maps and the location of errors in these models","volume":"A47","author":"Jones","year":"1991","journal-title":"Acta Crystallogr"},{"key":"10.1016\/0092-8674(95)90468-9_BIB17","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0092-8674(90)90453-L","article-title":"Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions","volume":"63","author":"Kissinger","year":"1990","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB18","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0092-8674(94)90231-3","article-title":"Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules","volume":"77","author":"Klemm","year":"1994","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/367083a0","article-title":"Evolution of distinct developmental functions of three Drosophila genes by acquisition of different cis-regulatory regions","volume":"367","author":"Li","year":"1994","journal-title":"Nature"},{"key":"10.1016\/0092-8674(95)90468-9_BIB20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/genetics\/121.1.77","article-title":"Definition of cis-acting elements regulating expression of the Drosophila melanogaster ninaE opsin gene by oligonucleotide-directed mutagenesis","volume":"121","author":"Mismer","year":"1989","journal-title":"Genetics"},{"key":"10.1016\/0092-8674(95)90468-9_BIB21","first-page":"6948","article-title":"Distinctive DNA conformation with enlarged major groove is found in Zn-finger-DNA and other protein-DNA complexes","volume":"91","author":"Nekludova","year":"1994"},{"key":"10.1016\/0092-8674(95)90468-9_BIB22","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/335321a0","article-title":"Crystal structure of TRP repressor\/operator complex at atomic resolution","volume":"335","author":"Otwinowski","year":"1988","journal-title":"Nature"},{"key":"10.1016\/0092-8674(95)90468-9_BIB23","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/0092-8674(89)90040-8","article-title":"The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors","volume":"59","author":"Qian","year":"1989","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB24","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1021\/ja00056a077","article-title":"NMR detection of hydration water in the intermolecular interface of a protein-DNA complex","volume":"115","author":"Qian","year":"1993","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/0092-8674(95)90468-9_BIB25","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0022-2836(92)90928-D","article-title":"Structure of a B-DNA decamer with a central T-A step: C-G-A-TT-A-A-C-G","volume":"225","author":"Quintana","year":"1992","journal-title":"J. Mol. Biol."},{"key":"10.1016\/0092-8674(95)90468-9_BIB26","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1126\/science.7914031","article-title":"Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans","volume":"265","author":"Quiring","year":"1994","journal-title":"Science"},{"key":"10.1016\/0092-8674(95)90468-9_BIB27","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.1093\/nar\/22.22.4574","article-title":"Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes","volume":"22","author":"Schafer","year":"1994","journal-title":"Nucl. Acids Res."},{"key":"10.1016\/0092-8674(95)90468-9_BIB28","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1107\/S0108767383001592","article-title":"Unbiased threedimensional refinement of hevy-atom parameters by correlation of origin-removed Patterson functions","volume":"A39","author":"Terwilliger","year":"1983","journal-title":"Acta Crystallogr."},{"key":"10.1016\/0092-8674(95)90468-9_BIB29","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0092-8674(89)90038-X","article-title":"A single amino acid can determine the DNA binding specificity of homeodomain proteins","volume":"59","author":"Treisman","year":"1989","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB30","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1101\/gad.5.4.594","article-title":"The Paired Box encodes a second DNA-binding domain in the Paired homeo domain protein","volume":"5","author":"Treisman","year":"1991","journal-title":"Genes Dev"},{"key":"10.1016\/0092-8674(95)90468-9_BIB31","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/bies.950140302","article-title":"The homeodomain: a new face for the helix-turn-helix?","volume":"14","author":"Treisman","year":"1992","journal-title":"Bioessays"},{"key":"10.1016\/0092-8674(95)90468-9_BIB32","first-page":"3692","article-title":"Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activity","volume":"92","author":"Underhill","year":"1995"},{"key":"10.1016\/0092-8674(95)90468-9_BIB33","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0960-9822(00)00010-5","article-title":"Homeotic genes seek partners","volume":"4","author":"White","year":"1994","journal-title":"Curr. Biol."},{"key":"10.1016\/0092-8674(95)90468-9_BIB34","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1101\/gad.7.11.2120","article-title":"Cooperative dimerization of Paired class homeo domains on DNA","volume":"7","author":"Wilson","year":"1993","journal-title":"Genes Dev."},{"key":"10.1016\/0092-8674(95)90468-9_BIB35","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0960-9822(95)00010-8","article-title":"Homeodomain proteins: cooperating to be different","volume":"5","author":"Wilson","year":"1995","journal-title":"Curr. Biol."},{"key":"10.1016\/0092-8674(95)90468-9_BIB36","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/0092-8674(91)90526-5","article-title":"Crystal structure of a MAT \u03b12 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions","volume":"67","author":"Wolberger","year":"1991","journal-title":"Cell"},{"key":"10.1016\/0092-8674(95)90468-9_BIB37","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0896-6273(91)90355-4","article-title":"Unusual topography of bovine rhodopsin promoter-lacZ fusion gene expression in transgenic mouse retinas","volume":"6","author":"Zack","year":"1991","journal-title":"Neuron"},{"key":"10.1016\/0092-8674(95)90468-9_BIB38","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1107\/S0108767389012158","article-title":"The use of Sayre's equation with solvent flatteing and histogram matching for phase extension and refinement of protein structures","volume":"A46","author":"Zhang","year":"1990","journal-title":"Acta Crystallogr"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0092867495904689?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0092867495904689?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T10:13:19Z","timestamp":1624529599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0092867495904689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1995,9]]}},"alternative-id":["0092867495904689"],"URL":"https:\/\/doi.org\/10.1016\/0092-8674(95)90468-9","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[1995,9]]}}}