{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:49:35Z","timestamp":1770976175174,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1992,5,1]],"date-time":"1992-05-01T00:00:00Z","timestamp":704678400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuroscience Letters"],"published-print":{"date-parts":[[1992,5]]},"DOI":"10.1016\/0304-3940(92)90569-s","type":"journal-article","created":{"date-parts":[[2003,4,25]],"date-time":"2003-04-25T06:26:26Z","timestamp":1051251986000},"page":"269-274","source":"Crossref","is-referenced-by-count":176,"title":["Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia"],"prefix":"10.1016","volume":"139","author":[{"given":"G.","family":"Wightman","sequence":"first","affiliation":[]},{"given":"V.E.R.","family":"Anderson","sequence":"additional","affiliation":[]},{"given":"J.","family":"Martin","sequence":"additional","affiliation":[]},{"given":"M.","family":"Swash","sequence":"additional","affiliation":[]},{"given":"B.H.","family":"Anderton","sequence":"additional","affiliation":[]},{"given":"D.","family":"Neary","sequence":"additional","affiliation":[]},{"given":"D.","family":"Mann","sequence":"additional","affiliation":[]},{"given":"P.","family":"Luthert","sequence":"additional","affiliation":[]},{"given":"P.N.","family":"Leigh","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/0304-3940(92)90569-S_BIB1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/298084a0","article-title":"Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants","volume":"298","author":"Anderton","year":"1982","journal-title":"Nature"},{"key":"10.1016\/0304-3940(92)90569-S_BIB2","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0167-4943(87)90021-5","article-title":"Frontal lobe degeneration of non-Alzheimer type: I. Neuropathology","volume":"6","author":"Brun","year":"1987","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/0304-3940(92)90569-S_BIB3","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0033-3182(86)72673-X","article-title":"A Neuropsychological study of motor neurone disease","volume":"27","author":"David","year":"1986","journal-title":"Psychosomatics"},{"key":"10.1016\/0304-3940(92)90569-S_BIB4","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1007\/BF00686799","article-title":"Motor neuron disease, parkinsonism and dementia","volume":"75","author":"Delisle","year":"1987","journal-title":"Acta Neuropathol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1159\/000116391","article-title":"Neuropsychological, electroencephalogram and brain computed tomography findings in motor neuron disease","volume":"29","author":"Gallassi","year":"1989","journal-title":"Eur. Neurol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB6","doi-asserted-by":"crossref","unstructured":"Gallo, J.-M., Hanger, D.P., Twist, E.C., Kosik, K.S. and Anderton, B.H., Expression and phosphorylation of a three-repeat isoform of tau in transfected non-neuronal cells, Biochem. J., in press.","DOI":"10.1042\/bj2860399"},{"key":"10.1016\/0304-3940(92)90569-S_BIB7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1136\/jnnp.52.2.185","article-title":"Cortical Lewy body dementia: clinical features and classification","volume":"52","author":"Gibb","year":"1989","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/0304-3940(92)90569-S_BIB8","doi-asserted-by":"crossref","unstructured":"Gunnarsson, L.-G., Dahlbom, K. and Strandman, E., Motor neuron disease and dementia reported among 13 members of a single family, Acta Neurol. Scand., in press.","DOI":"10.1111\/j.1600-0404.1991.tb04983.x"},{"key":"10.1016\/0304-3940(92)90569-S_BIB9","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0167-4943(87)90022-7","article-title":"Frontal lobe degeneration of non-Alzheimer type. II. Clinical picture and differential diagnosis","author":"Gustafson","year":"1987","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/0304-3940(92)90569-S_BIB10","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1136\/jnnp.49.11.1213","article-title":"Alzheimer neurofibrillary tangles contain phosphorylated and hidden neurofilament epitopes","volume":"49","author":"Haugh","year":"1986","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/0304-3940(92)90569-S_BIB11","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0022-510X(89)90158-5","article-title":"Total manifestations of amyotrophic lateral sclerosis","volume":"93","author":"Hayashi","year":"1989","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/0304-3940(92)90569-S_BIB12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/ana.410160306","article-title":"Dementia and motor neuron disease: morphometric, biochemical, and Golgi studies","volume":"16","author":"Horoupian","year":"1984","journal-title":"Ann. Neurol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/brain\/104.2.217","article-title":"Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review","volume":"104","author":"Hudson","year":"1981","journal-title":"Brain"},{"key":"10.1016\/0304-3940(92)90569-S_BIB14","series-title":"Advances in Neurology, Vol. 36, Human Motor Neuron Diseases","first-page":"61","article-title":"Pathology of amyotrophic lateral sclerosis","author":"Hughes","year":"1982"},{"key":"10.1016\/0304-3940(92)90569-S_BIB15","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1600-0404.1990.tb00950.x","article-title":"Cognitive impairment in amyotrophic lateral sclerosis and its relation to motor disabilities","volume":"81","author":"Iwasaki","year":"1990","journal-title":"Acta Neurol. Scand."},{"key":"10.1016\/0304-3940(92)90569-S_BIB16","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF00334500","article-title":"Presence of two different fibril subtypes in the Pick body: an immunoelectron microscopic study","volume":"81","author":"Kato","year":"1990","journal-title":"Acta Neuropathol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/brain\/104.1.61","article-title":"Familial dementia of adult onset with pathological findings of a \u2018non-speeific\u2019 nature","volume":"104","author":"Kim","year":"1981","journal-title":"Brain"},{"key":"10.1016\/0304-3940(92)90569-S_BIB18","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0304-3940(88)90081-X","article-title":"Ubiquitin deposits in anterior horn cells in motor neurone disease","volume":"93","author":"Leigh","year":"1988","journal-title":"Neurosci. Lett."},{"key":"10.1016\/0304-3940(92)90569-S_BIB19","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1093\/brain\/114.2.775","article-title":"Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis","volume":"114","author":"Leigh","year":"1991","journal-title":"Brain"},{"key":"10.1016\/0304-3940(92)90569-S_BIB20","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00005072-198807000-00001","article-title":"Alz-50, ubiquitin, and tau reactivity of neurofibrillary tangles, Pick bodies and Lewy bodies","volume":"47","author":"Love","year":"1988","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB21","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0304-3940(89)90003-7","article-title":"Inclusion bodies in motor cortex and brainstem of patients with motor neurone disease are detected by immunocytochemical localisation of ubiquitin","volume":"105","author":"Lowe","year":"1989","journal-title":"Neurosci. Lett."},{"key":"10.1016\/0304-3940(92)90569-S_BIB22","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0304-3940(88)90296-0","article-title":"A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localization of ubiquitin-protein conjugates","volume":"94","author":"Lowe","year":"1988","journal-title":"Neurosci. Lett."},{"key":"10.1016\/0304-3940(92)90569-S_BIB23","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/BF00307702","article-title":"Lobar atrophy with dense-core (brain stem type) Lewy bodies in a patient with dementia","volume":"80","author":"Masliah","year":"1990","journal-title":"Acta Neuropathol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB24","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0304-3940(90)90419-A","article-title":"Ubiquitinated filamentous inclusions in spinal cord of patients with motor neuron disease","volume":"114","author":"Migheli","year":"1990","journal-title":"Neurosci. Lett."},{"key":"10.1016\/0304-3940(92)90569-S_BIB25","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1136\/jnnp.47.9.953","article-title":"Presenile dementia with motor neuron disease in Japan: clinico-pathological review of 26 cases","volume":"47","author":"Mitsuyama","year":"1984","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/0304-3940(92)90569-S_BIB26","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0167-4943(87)90026-4","article-title":"Presenile dementia combined with amyotrophy: a review of 34 Japanese cases","volume":"6","author":"Morita","year":"1987","journal-title":"Arch. Gerontol. Geriatr."},{"key":"10.1016\/0304-3940(92)90569-S_BIB27","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/ana.410160408","article-title":"Classic and generalized variants of Pick's disease: a clinicopathological, ultrastructural, and immunocytochemical comparative study","volume":"16","author":"Munoz-Garcia","year":"1984","journal-title":"Ann. Neurol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB28","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/ana.410270407","article-title":"Immunocytochemical and ultrastructural studies of Pick's disease","volume":"27","author":"Murayama","year":"1990","journal-title":"Ann. Neurol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB29","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/ana.410270208","article-title":"Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis","volume":"27","author":"Murayama","year":"1990","journal-title":"Ann. Neurol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB30","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/BF00695603","article-title":"Immunohistochemical localisation of neurofilament protein in neuronal degenerations","volume":"64","author":"Nakazato","year":"1984","journal-title":"Acta Neuropathol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB31","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1136\/jnnp.53.11.929","article-title":"Non Alzheimer's disease forms of cerebral atrophy","volume":"53","author":"Neary","year":"1990","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/0304-3940(92)90569-S_BIB32","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1136\/jnnp.53.1.23","article-title":"Frontal lobe dementia and motor neuron disease","volume":"53","author":"Neary","year":"1990","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/0304-3940(92)90569-S_BIB33","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/jnnp.51.3.353","article-title":"Dementia of frontal lobe type","volume":"51","author":"Neary","year":"1988","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/0304-3940(92)90569-S_BIB34","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0304-3940(91)90469-A","article-title":"New ubiquitin-positive intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis","volume":"129","author":"Okamoto","year":"1991","journal-title":"Neurosci. Lett."},{"key":"10.1016\/0304-3940(92)90569-S_BIB35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.cb.03.110187.000245","article-title":"Ubiquitin-mediated pathways for intracellular proteolysis","volume":"3","author":"Rechsteiner","year":"1987","journal-title":"Ann. Rev. Cell Biol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB36","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0304-3940(90)90480-W","article-title":"Antibodies raised against different portions of A4 protein identify a subset of plaques in Down's syndrome","volume":"115","author":"Spargoe","year":"1990","journal-title":"Neurosci. Lett."},{"key":"10.1016\/0304-3940(92)90569-S_BIB37","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/00005072-198809000-00004","article-title":"Parkinson's disease and dementia with neuronal inclusions in the cerebral cortex: Lewy bodies or Pick bodies","volume":"47","author":"Teller-Boreich","year":"1988","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB38","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1007\/BF00686617","article-title":"Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes","volume":"73","author":"Ulrich","year":"1987","journal-title":"Acta Neuropathol."},{"key":"10.1016\/0304-3940(92)90569-S_BIB39","first-page":"4840","article-title":"ATP-induced loss of Alz-50 immunoreactivity with the A68 proteins from Alzheimer brain is mediated by ubiquitin","volume":"87","author":"Vincent","year":"1990"},{"key":"10.1016\/0304-3940(92)90569-S_BIB40","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/BF00296119","article-title":"Distinctive, rapid, and easy labelling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain","volume":"79","author":"Yamaguchi","year":"1990","journal-title":"Acta Neuropathol."}],"container-title":["Neuroscience Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:030439409290569S?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:030439409290569S?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T00:26:22Z","timestamp":1553214382000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/030439409290569S"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,5]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,5]]}},"alternative-id":["030439409290569S"],"URL":"https:\/\/doi.org\/10.1016\/0304-3940(92)90569-s","relation":{},"ISSN":["0304-3940"],"issn-type":[{"value":"0304-3940","type":"print"}],"subject":[],"published":{"date-parts":[[1992,5]]}}}