{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T15:33:01Z","timestamp":1762270381561},"reference-count":36,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1983,12,1]],"date-time":"1983-12-01T00:00:00Z","timestamp":439084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gene"],"published-print":{"date-parts":[[1983,12]]},"DOI":"10.1016\/0378-1119(83)90037-9","type":"journal-article","created":{"date-parts":[[2003,2,12]],"date-time":"2003-02-12T03:07:18Z","timestamp":1045019238000},"page":"67-78","source":"Crossref","is-referenced-by-count":112,"title":["Mutational cloning in Streptomyces and the isolation of antibiotic production genes"],"prefix":"10.1016","volume":"26","author":[{"given":"Keith F.","family":"Chater","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia J.","family":"Bruton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0378-1119(83)90037-9_BIB1","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1128\/AEM.30.2.324-326.1975","article-title":"Estimate of the genome size by renaturation studies in Streptomyces","volume":"30","author":"Benigni","year":"1975","journal-title":"Appl. Microbiol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/BF00331128","article-title":"Gene expression in Streptomyces: Construction and application of promoter-probe plasmids in Streptomyces lividans","volume":"187","author":"Bibb","year":"1982","journal-title":"Mol. Gen. Genet."},{"key":"10.1016\/0378-1119(83)90037-9_BIB3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF00330831","article-title":"Physical and genetical characterization of a second sex factor, SCP2, for Streptomyces coelicolor","volume":"154","author":"Bibb","year":"1977","journal-title":"Mol. Gen. Genet."},{"key":"10.1016\/0378-1119(83)90037-9_BIB4","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/284526a0","article-title":"A DNA cloning system for interspecies gene transfer in antibiotic-producing Streptomyces","volume":"284","author":"Bibb","year":"1980","journal-title":"Nature"},{"key":"10.1016\/0378-1119(83)90037-9_BIB5","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0022-2836(80)90283-1","article-title":"Analysis of gene control systems by DNA fusion and cloning in Escherichia coli","volume":"138","author":"Casadaban","year":"1980","journal-title":"J. Mol. Biol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB6","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0378-1119(81)90114-1","article-title":"Restriction mapping of the DNA of the Streptomyces temperate phage \u03c6C31 and its derivatives","volume":"14","author":"Chater","year":"1981","journal-title":"Gene"},{"key":"10.1016\/0378-1119(83)90037-9_BIB7","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0378-1119(82)90185-8","article-title":"The expression of Streptomyces and Escherichia coli drug-resistance determinants cloned into the Streptomyces phage \u03c6C31","volume":"19","author":"Chater","year":"1982","journal-title":"Gene"},{"key":"10.1016\/0378-1119(83)90037-9_BIB8","first-page":"69","article-title":"Gene cloning in Streptomyces","volume":"97","author":"Chater","year":"1982","journal-title":"Curr. Topics Microbiol. Immunol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB9","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1128\/JB.128.2.644-650.1976","article-title":"Restriction of a bacteriophage of Streptomyces albus G involving endonuclease SalI","volume":"128","author":"Chater","year":"1976","journal-title":"J. Bacteriol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB10","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/BF00331065","article-title":"Cloning of a Streptomyces gene for an O-methyltransferase involved in antibiotic biosynthesis","volume":"190","author":"Feitelson","year":"1983","journal-title":"Mol. Gen. Genet."},{"key":"10.1016\/0378-1119(83)90037-9_BIB11","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/0003-2697(80)90553-9","article-title":"A rapid and efficient procedure for the isolation of DNA from agarose gels","volume":"106","author":"Girvitz","year":"1980","journal-title":"Anal. Biochem."},{"key":"10.1016\/0378-1119(83)90037-9_BIB12","doi-asserted-by":"crossref","first-page":"386","DOI":"10.7164\/antibiotics.27.386","article-title":"New antibiotics, methylenomycin A and B, I. Producing organism, fermentation and isolation, biological activities and physical and chemical properties","volume":"27","author":"Haneishi","year":"1974","journal-title":"J. Antibiot."},{"key":"10.1016\/0378-1119(83)90037-9_BIB13","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0378-1119(83)90100-2","article-title":"The restriction mapping of c gene deletions in Streptomyces bacteriophage \u03c6C31 and their use in cloning vector development","volume":"22","author":"Harris","year":"1983","journal-title":"Gene"},{"key":"10.1016\/0378-1119(83)90037-9_BIB14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0165-022X(79)90004-6","article-title":"Small-scale techniques for the analysis of recombinant plasmids","volume":"1","author":"Hepburn","year":"1979","journal-title":"J. Biochem. Biophys. Methods"},{"key":"10.1016\/0378-1119(83)90037-9_BIB15","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1128\/MMBR.31.4.373-403.1967","article-title":"Genetic analysis and genome structure in Streptomyces coelicolor","volume":"31","author":"Hopwood","year":"1967","journal-title":"Bacteriol. Rev."},{"key":"10.1016\/0378-1119(83)90037-9_BIB16","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1128\/MMBR.37.3.371-405.1973","article-title":"Recent advances in Streptomyces coelicolor genetics","volume":"37","author":"Hopwood","year":"1973","journal-title":"Bacteriol. Rev."},{"key":"10.1016\/0378-1119(83)90037-9_BIB17","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1099\/00221287-77-1-187","article-title":"Transfer of a plasmid between Streptomyces species","volume":"77","author":"Hopwood","year":"1973","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB18","series-title":"Plasmid of medical, Environmental and Commercial Importance","first-page":"245","article-title":"Plasmids in Streptomyces coelicolor and related species","author":"Hopwood","year":"1979"},{"key":"10.1016\/0378-1119(83)90037-9_BIB19","first-page":"119","article-title":"DNA cloning in Streptomyces: systems and strategies","volume":"Vol. 4","author":"Hopwood","year":"1982"},{"key":"10.1016\/0378-1119(83)90037-9_BIB20","first-page":"123","article-title":"Biosynthesis of methylenomycin A: a plasmid determined antibiotic","volume":"Vol. IV","author":"Hornemann","year":"1981"},{"key":"10.1016\/0378-1119(83)90037-9_BIB21","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/BF00330791","article-title":"p1J101, a multi-copy broad host-range Streptomyces plasmid: functional analysis and development of DNA cloning vectors","volume":"185","author":"Kieser","year":"1982","journal-title":"Mol. Gen. Genet."},{"key":"10.1016\/0378-1119(83)90037-9_BIB22","article-title":"Genetic studies on Streptomyces coelicolor plasmid one","author":"Kirby","year":"1976"},{"key":"10.1016\/0378-1119(83)90037-9_BIB23","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/254265a0","article-title":"Plasmid-determined antibiotic synthesis and resistance in Streptomyces coelicolor","volume":"254","author":"Kirby","year":"1975","journal-title":"Nature"},{"key":"10.1016\/0378-1119(83)90037-9_BIB24","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1099\/00221287-98-1-239","article-title":"Genetic determination of methylenomycin synthesis by the SCP1 plasmid of Streptomyces coelicolor A3(2)","volume":"98","author":"Kirby","year":"1977","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB25","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1128\/JVI.9.2.258-262.1972","article-title":"Characterization of temperate actinophage \u03c6C31 isolated from Streptomyces coelicolor A3(2)","volume":"9","author":"Lomovskaya","year":"1972","journal-title":"J. Virol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB26","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1128\/mr.44.2.206-229.1980","article-title":"Genetics and molecular biology of Streptomyces bacteriophages","volume":"44","author":"Lomovskaya","year":"1980","journal-title":"Microbiol. Rev."},{"key":"10.1016\/0378-1119(83)90037-9_BIB27","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/0022-2836(79)90271-7","article-title":"Molecular cloning of the T4 ligase gene from bacteriophage T4, II. Amplification and preparation of the gene product","volume":"132","author":"Murray","year":"1979","journal-title":"J. Mol. Biol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB28","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1128\/JB.151.3.1078-1085.1982","article-title":"Small DNA-free liposomes stimulate transfection of Streptomyces protoplasts","volume":"151","author":"Rodicio","year":"1982","journal-title":"J. Bacteriol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB29","article-title":"The glycerol utilization operon of Streptomyces coelicolor: genetic mapping of gyl mutations and the analysis of cloned gyl DNA","author":"Seno","year":"1983","journal-title":"Mol. Gen. Genet."},{"key":"10.1016\/0378-1119(83)90037-9_BIB30","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1126\/science.7046050","article-title":"Lethal disruption of the yeast actin gene by integrative DNA transformation","volume":"217","author":"Shortle","year":"1982","journal-title":"Science"},{"key":"10.1016\/0378-1119(83)90037-9_BIB31","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0022-2836(75)80083-0","article-title":"Detection of specific sequences among DNA fragments separated by gel electrophoresis","volume":"98","author":"Southern","year":"1975","journal-title":"J. Mol. Biol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB32","first-page":"99","article-title":"Development of a DNA cloning system in Streptomyces using phage cloning vectors","volume":"6","author":"Suarez","year":"1981","journal-title":"Ci. Biol. Mol. Cel. Biol. (Portugal)"},{"key":"10.1016\/0378-1119(83)90037-9_BIB33","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/286525a0","article-title":"DNA cloning in Streptomyces: resistance genes from antibiotic producing species","volume":"286","author":"Thompson","year":"1980","journal-title":"Nature"},{"key":"10.1016\/0378-1119(83)90037-9_BIB34","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0378-1119(82)90086-5","article-title":"Physical analysis of antibiotic-resistance genes from Streptomyces and their use in vector construction","volume":"20","author":"Thompson","year":"1982","journal-title":"Gene"},{"key":"10.1016\/0378-1119(83)90037-9_BIB35","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1128\/JB.151.2.668-677.1982","article-title":"Cloning of antibiotic resistance and nutritional genes in Streptomyces","volume":"151","author":"Thompson","year":"1982","journal-title":"J. Bacteriol."},{"key":"10.1016\/0378-1119(83)90037-9_BIB36","article-title":"Physical studies of Streptomyces plasmids","author":"Westpheling","year":"1980"}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0378111983900379?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0378111983900379?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T07:22:17Z","timestamp":1622791337000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0378111983900379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,12]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983,12]]}},"alternative-id":["0378111983900379"],"URL":"https:\/\/doi.org\/10.1016\/0378-1119(83)90037-9","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[1983,12]]}}}