{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T19:47:56Z","timestamp":1762112876375},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1992,5,1]],"date-time":"1992-05-01T00:00:00Z","timestamp":704678400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuron"],"published-print":{"date-parts":[[1992,5]]},"DOI":"10.1016\/0896-6273(92)90212-v","type":"journal-article","created":{"date-parts":[[2004,5,4]],"date-time":"2004-05-04T12:29:33Z","timestamp":1083673773000},"page":"975-982","source":"Crossref","is-referenced-by-count":31,"title":["Repulsion between tetraethylammonium ions in cloned voltage-gated potassium channels"],"prefix":"10.1016","volume":"8","author":[{"given":"C.F.","family":"Newland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.P.","family":"Adelman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.L.","family":"Tempel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Almers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0896-6273(92)90212-V_BIB1","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1113\/jphysiol.1984.sp015352","article-title":"Non-selective conductance in calcium channels of frog muscle: calcium selectivity in a single-file pore","volume":"353","author":"Almers","year":"1984","journal-title":"J. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB2","first-page":"61","article-title":"The mechanism of ion selectivity in calcium channels of skeletal muscle membrane","volume":"33","author":"Almers","year":"1986","journal-title":"Prog. Zool."},{"key":"10.1016\/0896-6273(92)90212-V_BIB3","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1085\/jgp.54.5.553","article-title":"Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons","volume":"54","author":"Armstrong","year":"1969","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB4","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1085\/jgp.58.4.413","article-title":"Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons","volume":"58","author":"Armstrong","year":"1971","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB5","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1085\/jgp.80.5.663","article-title":"Block of squid axon K+ channels by internally and externally applied barium ions","volume":"80","author":"Armstrong","year":"1982","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1085\/jgp.84.1.1","article-title":"Ion conductance and selectivity of single calcium-activated potassium channels in cultured rat muscle","volume":"84","author":"Blatz","year":"1984","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB7","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/352026b0","article-title":"Simplified gene nomenclature","volume":"352","author":"Chandy","year":"1991","journal-title":"Nature"},{"key":"10.1016\/0896-6273(92)90212-V_BIB8","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1126\/science.2539643","article-title":"Expression of a cloned rat brain potassium channel in Xenopus oocytes","volume":"244","author":"Christie","year":"1989","journal-title":"Science"},{"key":"10.1016\/0896-6273(92)90212-V_BIB9","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0896-6273(90)90052-H","article-title":"Heteropolymeric potassium channels expressed in Xenopus oocytes from cloned subunits","volume":"2","author":"Christie","year":"1990","journal-title":"Neuron"},{"key":"10.1016\/0896-6273(92)90212-V_BIB10","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0166-2236(90)90160-C","article-title":"Pursuing the structure and function of voltage-gated channels","volume":"13","author":"Guy","year":"1990","journal-title":"Trends Neurosci."},{"key":"10.1016\/0896-6273(92)90212-V_BIB11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF00656997","article-title":"Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches","volume":"391","author":"Hamill","year":"1981","journal-title":"Pfl\u00fcgers Arch."},{"key":"10.1016\/0896-6273(92)90212-V_BIB12","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1126\/science.2000495","article-title":"Exchange of conduction pathways between two related K+ channels","volume":"251","author":"Hartmann","year":"1991","journal-title":"Science"},{"key":"10.1016\/0896-6273(92)90212-V_BIB13","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/309453a0","article-title":"Mechanism of ion permeation through calcium channels","volume":"309","author":"Hess","year":"1984","journal-title":"Nature"},{"key":"10.1016\/0896-6273(92)90212-V_BIB14","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1085\/jgp.50.5.1287","article-title":"The selective inhibition of delayed potassium currents in nerve by tetraethylammonium ion","volume":"50","author":"Hille","year":"1967","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB15","series-title":"Ion Channels of Excitable Membranes","first-page":"280","article-title":"Mechanisms of block","author":"Hille","year":"1984"},{"key":"10.1016\/0896-6273(92)90212-V_BIB16","first-page":"89","article-title":"Ion movements in pores formed by gramicidin A","volume":"Vol. 3","author":"Hladky","year":"1979"},{"key":"10.1016\/0896-6273(92)90212-V_BIB17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1113\/jphysiol.1955.sp005291","article-title":"The potassium permeability of a giant nerve fibre","volume":"128","author":"Hodgkin","year":"1955","journal-title":"J. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB18","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0166-2236(90)90123-R","article-title":"How might the diversity of potassium channels be generated?","volume":"13","author":"Jan","year":"1990","journal-title":"Trends Neurosci."},{"key":"10.1016\/0896-6273(92)90212-V_BIB19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF01869197","article-title":"The total electrostatic potential in a gramicidin channel","volume":"78","author":"Jordan","year":"1984","journal-title":"J. Membr. Biol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB20","doi-asserted-by":"crossref","first-page":"7583","DOI":"10.1016\/S0021-9258(20)89487-3","article-title":"Interaction between tetraethylammonium and amino acid residues in the pore of cloned voltage-dependent potassium channels","volume":"266","author":"Kavanaugh","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/0896-6273(92)90212-V_BIB21","doi-asserted-by":"crossref","first-page":"c583","DOI":"10.1152\/ajpcell.1991.261.4.C583","article-title":"Internal and external TEA block in single cloned K+ channels","volume":"261","author":"Kirsch","year":"1991","journal-title":"Am. J. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB22","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/BF01871455","article-title":"Two ion-selecting filters in the calcium channel of the somatic membrane of mollusc neurons","volume":"76","author":"Kostyuk","year":"1983","journal-title":"J. Membr. Biol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB23","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1126\/science.2455345","article-title":"Three-dimensional structure at 0.83 \u00c5 of the uncomplexed form of the transmembrane ion channel peptide gramicidin A","volume":"241","author":"Langs","year":"1988","journal-title":"Science"},{"key":"10.1016\/0896-6273(92)90212-V_BIB24","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0006-3495(78)85486-1","article-title":"Electrostatic calculations for an ion channel. II. Kinetic behavior of the gramicidin A channel","volume":"22","author":"Levitt","year":"1978","journal-title":"Biophys. J."},{"key":"10.1016\/0896-6273(92)90212-V_BIB25","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1126\/science.2218530","article-title":"Mutations affecting TEA blockade and ion permeation in voltage-activated K+ channels","volume":"250","author":"MacKinnon","year":"1990","journal-title":"Science"},{"key":"10.1016\/0896-6273(92)90212-V_BIB26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/BF00582635","article-title":"Patch clamp measurements on Xenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels","volume":"407","author":"Methfessel","year":"1986","journal-title":"Pfl\u00fcgers Arch."},{"key":"10.1016\/0896-6273(92)90212-V_BIB27","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1085\/jgp.92.5.549","article-title":"Potassium blocks barium permeation through a calcium activated potassium channel","volume":"92","author":"Neyton","year":"1988","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB28","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1085\/jgp.92.5.569","article-title":"Discrete Ba2+ block as a probe of ion occupancy and pore structure in the high conductance Ca2+ activated K+ channel","volume":"92","author":"Neyton","year":"1988","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB29","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1113\/jphysiol.1987.sp016833","article-title":"The action of external tetraethylammonium ions on unitary delayed rectifier potassium channels of frog skeletal muscle","volume":"393","author":"Spruce","year":"1987","journal-title":"J. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BFb0035345","article-title":"Tetraethylammonium ions and the potassium permeability of excitable cells","volume":"97","author":"Stanfield","year":"1983","journal-title":"Rev. Physiol. Biochem. Pharmacol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB31","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1146\/annurev.bb.20.060191.000433","article-title":"Structure-function studies of voltage-gated ion channels","volume":"20","author":"St\u00fchmer","year":"1991","journal-title":"Annu. Rev. Biophys. Biophys. Chem."},{"key":"10.1016\/0896-6273(92)90212-V_BIB32","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/331143a0","article-title":"Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes","volume":"331","author":"Timpe","year":"1988","journal-title":"Nature"},{"key":"10.1016\/0896-6273(92)90212-V_BIB33","first-page":"390","article-title":"Location of monovalent cation binding sites in the gramicidin channel","volume":"79","author":"Urry","year":"1982"},{"key":"10.1016\/0896-6273(92)90212-V_BIB34","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1126\/science.221.4615.1064","article-title":"Is the gramicidin A transmembrane channel single-stranded or double-stranded helix?","volume":"221","author":"Urry","year":"1983","journal-title":"Science"},{"key":"10.1016\/0896-6273(92)90212-V_BIB35","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0022-2836(80)90220-X","article-title":"Binding of thallium and other cations to the gramicidin A channel: equilibrium dialysis study of gramicidin in phosphatidylcholine vesicles","volume":"143","author":"Veatch","year":"1980","journal-title":"J. Mol. Biol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB36","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/bip.360220152","article-title":"Gramicidin A adopts distinctly different conformations in membranes and in organic solvents","volume":"22","author":"Wallace","year":"1983","journal-title":"Biopolymers"},{"key":"10.1016\/0896-6273(92)90212-V_BIB37","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1126\/science.2455344","article-title":"The gramicidin pore: crystal structure of a cesium complex","volume":"241","author":"Wallace","year":"1988","journal-title":"Science"},{"key":"10.1016\/0896-6273(92)90212-V_BIB38","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1085\/jgp.84.2.157","article-title":"Ionic permeation and blockade of Ca2+activated K+ channels of bovine chroamffin cells","volume":"84","author":"Yellen","year":"1984","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/0896-6273(92)90212-V_BIB39","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1126\/science.2000494","article-title":"Mutations affecting internal TEA blockade identify the pore-forming region of a K+ channel","volume":"251","author":"Yellen","year":"1991","journal-title":"Science"},{"key":"10.1016\/0896-6273(92)90212-V_BIB40","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/349700a0","article-title":"Alteration of ionic selectivity of a K+ channel by mutation of the H5 region","volume":"349","author":"Yool","year":"1991","journal-title":"Nature"}],"container-title":["Neuron"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:089662739290212V?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:089662739290212V?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T08:46:10Z","timestamp":1623919570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/089662739290212V"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1992,5]]}},"alternative-id":["089662739290212V"],"URL":"https:\/\/doi.org\/10.1016\/0896-6273(92)90212-v","relation":{},"ISSN":["0896-6273"],"issn-type":[{"value":"0896-6273","type":"print"}],"subject":[],"published":{"date-parts":[[1992,5]]}}}