{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T09:47:28Z","timestamp":1772272048545,"version":"3.50.1"},"reference-count":51,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1998,5,1]],"date-time":"1998-05-01T00:00:00Z","timestamp":893980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":5556,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mechanisms of Development"],"published-print":{"date-parts":[[1998,5]]},"DOI":"10.1016\/s0925-4773(98)00047-1","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T22:45:51Z","timestamp":1027637151000},"page":"159-168","source":"Crossref","is-referenced-by-count":107,"title":["Xpat, a gene expressed specifically in germ plasm and primordial germ cells of Xenopus laevis"],"prefix":"10.1016","volume":"73","author":[{"given":"Clare","family":"Hudson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugh R","family":"Woodland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0925-4773(98)00047-1_BIB1","first-page":"251","article-title":"Cytological analyses of factors which determine the number of primordial germ cells (PGCs) in Xenopus laevis","volume":"90","author":"Akita","year":"1985","journal-title":"J. Embryol. Exp. Morphol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB2","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1242\/dev.110.3.955","article-title":"Posttranscriptional regulation of ornithine decarboxylase in Xenopus laevis oocytes","volume":"110","author":"Bassez","year":"1990","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB3","first-page":"79","article-title":"The effect of egg rotation on the differentiation of primordial germ cells in Xenopus laevis","volume":"90","author":"Cleine","year":"1985","journal-title":"J. Embryol. Exp. Morphol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB4","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1021\/bc00024a005","article-title":"Biologically-active interleukin 2-ricin A-chain fusion proteins may require intracellular proteolytic cleavage to exhibit a cytotoxic effect","volume":"4","author":"Cook","year":"1993","journal-title":"Bioconj. Chem."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB5","doi-asserted-by":"crossref","first-page":"4471","DOI":"10.1002\/j.1460-2075.1993.tb06136.x","article-title":"Secretion and mesoderm-inducing activity of the TGF-\u03b2-related domain of Xenopus Vg1","volume":"12","author":"Dale","year":"1993","journal-title":"EMBO J."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB6","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1126\/science.276.5315.1128","article-title":"Localisation of Xenopus Vg1 mRNA by VERA protein and the endoplasmic recticulum","volume":"279","author":"Deshler","year":"1997","journal-title":"Science"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB7","doi-asserted-by":"crossref","first-page":"6025","DOI":"10.1073\/pnas.93.12.6025","article-title":"Suppression subtractive hybridization \u2013 a method for generating differentially regulated or tissue-specific cDNA probes and libraries","volume":"93","author":"Diatchenko","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/jmor.1051360203","article-title":"Oogenesis in Xenopus laevis (Daudin): Stages of oocytes in laboratory maintained animals","volume":"136","author":"Dumont","year":"1972","journal-title":"J. Morphol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB9","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/358387a0","article-title":"Induction of germ cell formation by Oskar","volume":"358","author":"Ephrussi","year":"1992","journal-title":"Nature"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB10","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/0092-8674(94)90013-2","article-title":"Staufen protein associates with the 3\u2032-UTR of bicoid messenger-RNA to form particles that move in a microtubule-dependent manner","volume":"79","author":"Ferrandon","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB11","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1093\/emboj\/16.7.1751","article-title":"RNA\u2013RNA interaction is required for the formation of specific bicoid mRNA 3\u2032-UTR Staufen ribonucleoprotein particles","volume":"16","author":"Ferrandon","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB12","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1242\/dev.121.1.201","article-title":"Patterns of localization and cytoskeletal association of 2 vegetally localized RNAs, Vg1 and Xcat-2","volume":"121","author":"Forristall","year":"1995","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB13","doi-asserted-by":"crossref","first-page":"7164","DOI":"10.1073\/pnas.89.15.7164","article-title":"The 3\u2032 untranslated region of localised maternal messages contains a conserved motif involved in mRNA localization","volume":"89","author":"Gottlieb","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB14","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0959-437X(96)80059-1","article-title":"RNA localization and the development of asymmetry during Drosophila oogenesis","volume":"6","author":"Grunert","year":"1996","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB15","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0091-679X(08)60307-6","article-title":"In situ hybridization \u2013 an improved whole-mount method for Xenopus embryos","volume":"36","author":"Harland","year":"1991","journal-title":"Methods Cell Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB16","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/0012-1606(84)90303-8","article-title":"The mitochondrial cloud of Xenopus oocytes \u2013 the source of germinal granule material","volume":"105","author":"Heasman","year":"1984","journal-title":"Dev. Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB17","unstructured":"Heasman, J., Wylie, C.C., 1983. Amphibian primordial germ cells \u2013 what can they tell us about directed cell migration? In: McLaren, A., Wylie, C.C. (Eds.), Current Problems in Germ Cell Differentiation. British Society for Developmental Biology. Symposium 7, Cambridge University Press, Cambridge, New York, Melbourne, pp. 73\u201390."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB18","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1242\/dev.124.9.1689","article-title":"A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation","volume":"124","author":"Horb","year":"1997","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB19","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0092-8674(00)80423-7","article-title":"Xsox17-\u03b1 and -\u03b2 mediate endoderm formation in Xenopus","volume":"91","author":"Hudson","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB20","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1440-169X.1986.00563.x","article-title":"Direct evidence for the presence of germ cell determinant in vegetal pole cytoplasm of Xenopus laevis and in a subcellular fraction of it","volume":"28","author":"Ikenishi","year":"1986","journal-title":"Dev. Growth Diff."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB21","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1242\/dev.102.3.527","article-title":"The positional effect of presumptive primordial germ cells (PGCs) on their differentiation into PGCs in Xenopus","volume":"102","author":"Ikenishi","year":"1988","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB22","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/0168-9525(96)99990-4","article-title":"Enzymatic removal of vitelline membrane and other protocol modifications for whole-mount in-situ hybridization of embryos","volume":"12","author":"Islam","year":"1996","journal-title":"Trends Genet."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB23","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1126\/science.7939714","article-title":"Vertebrate embryonic induction \u2013 mesodermal and neural patterning","volume":"266","author":"Kessler","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB24","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1126\/science.7520603","article-title":"Delocalisation of Vg1 messenger RNA from the vegetal cortex in Xenopus oocytes after destruction of Xlsirt RNA","volume":"265","author":"Kloc","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB25","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1242\/dev.121.2.287","article-title":"Two distinct pathways for the localization of RNAs at the vegetal cortex in Xenopus oocytes","volume":"121","author":"Kloc","year":"1995","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB26","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1126\/science.7505061","article-title":"Translocation of repetitive RNA sequences with the germ plasm in Xenopus oocytes","volume":"262","author":"Kloc","year":"1993","journal-title":"Science"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB27","first-page":"193","article-title":"Localization of mitochondrial large ribosomal RNA in germinal granules and the consequent segregation of germ line","volume":"38","author":"Kobayashi","year":"1994","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB28","first-page":"701","article-title":"Highly efficient subtractive hybridisation of cDNA","volume":"20","author":"Lukyanov","year":"1994","journal-title":"Bioorg. Chem."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB29","doi-asserted-by":"crossref","first-page":"4001","DOI":"10.1242\/dev.122.12.4001","article-title":"Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation","volume":"122","author":"Lustig","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB30","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/328080a0","article-title":"Translocation of a localized maternal messenger-RNA to the vegetal pole of Xenopus oocytes","volume":"328","author":"Melton","year":"1987","journal-title":"Nature"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB31","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1006\/dbio.1995.8048","article-title":"Messenger-RNA localization during development","volume":"172","author":"Micklem","year":"1995","journal-title":"Dev. Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB32","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1242\/dev.117.1.377","article-title":"A mRNA localized to the vegetal cortex of Xenopus oocytes encodes a protein with a nanos-like zinc finger domain","volume":"117","author":"Mosquera","year":"1993","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB33","doi-asserted-by":"crossref","first-page":"14608","DOI":"10.1073\/pnas.93.25.14608","article-title":"Complex formation between stage specific oocyte factors and a Xenopus messenger RNA localization element","volume":"93","author":"Mowry","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB34","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1126\/science.1546297","article-title":"Vegetal messenger-RNA localization directed by a 340-NT RNA sequence element in Xenopus oocytes","volume":"255","author":"Mowry","year":"1992","journal-title":"Science"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB35","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1002\/pro.5560051005","article-title":"Construction and analysis of a profile library characterising groups of structurally known proteins","volume":"5","author":"Ogiwara","year":"1996","journal-title":"Protein Sci."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB36","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1242\/dev.103.3.507","article-title":"Relocation and reorganization of germ plasm in Xenopus embryos after fertilization","volume":"103","author":"Ressom","year":"1988","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB37","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0925-4773(95)00388-H","article-title":"Developmental effects of over-expression of normal and mutated forms of a Xenopus NF-\u03baB homolog","volume":"52","author":"Richardson","year":"1995","journal-title":"Mech. Dev."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB38","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1006\/dbio.1993.1142","article-title":"Dynamics of germ plasm localization and its inhibition by ultraviolet irradiation in early cleavage Xenopus embryos","volume":"157","author":"Savage","year":"1993","journal-title":"Dev. Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB39","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/0960-9822(93)90079-4","article-title":"RNA zipcodes for cytoplasmic addresses","volume":"3","author":"Singer","year":"1993","journal-title":"Curr. Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB40","doi-asserted-by":"crossref","unstructured":"Smith, L.D., Williams, M.A., 1975. Germinal cytoplasm and determination of the primordial germ cells. In: Markert, C.L., Papaconstantinou, J. (Eds.), The Developmental Biology of Reproduction. Academic Press, New York, San Francisco, London, pp. 3\u201324.","DOI":"10.1016\/B978-0-12-612979-3.50008-X"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB41","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0092-8674(95)90324-0","article-title":"The intracellular localization of messenger RNAs","volume":"81","author":"St Johnston","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB42","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0092-8674(92)90466-P","article-title":"The origin of pattern and polarity in the Drosophila embryo","volume":"68","author":"St Johnston","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB43","doi-asserted-by":"crossref","first-page":"4179","DOI":"10.1242\/dev.122.12.4179","article-title":"The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation","volume":"122","author":"Stennard","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB44","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0168-9525(94)90134-1","article-title":"Vg1 and regional specification in vertebrates \u2013 a new role for an old molecule","volume":"10","author":"Vize","year":"1994","journal-title":"Trends Genet."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB45","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1146\/annurev.cellbio.12.1.365","article-title":"Germ cell development in Drosophila","volume":"12","author":"Williamson","year":"1996","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB46","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/0092-8674(86)90623-9","article-title":"Tissue-specific expression of actin genes injected into Xenopus embryos","volume":"47","author":"Wilson","year":"1986","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB47","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0012-1606(85)90119-8","article-title":"Primordial germ cells of Xenopus laevis are not irreversibly determined early in development","volume":"112","author":"Wylie","year":"1985","journal-title":"Dev. Biol."},{"key":"10.1016\/S0925-4773(98)00047-1_BIB48","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1038\/336592a0","article-title":"The maternal messenger RNA Vg1 is correctly localized following injection into Xenopus oocytes","volume":"336","author":"Yisraeli","year":"1988","journal-title":"Nature"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB49","doi-asserted-by":"crossref","first-page":"4119","DOI":"10.1242\/dev.122.12.4119","article-title":"Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning","volume":"122","author":"Zhang","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB50","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1242\/dev.122.9.2947","article-title":"Localization of Xcat-2 RNA, a putative germ plasm component, to the mitochondrial cloud in Xenopus Stage I oocytes","volume":"122","author":"Zhou","year":"1996","journal-title":"Development"},{"key":"10.1016\/S0925-4773(98)00047-1_BIB51","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1006\/dbio.1996.0249","article-title":"RNA transport to the vegetal cortex of Xenopus oocytes","volume":"179","author":"Zhou","year":"1996","journal-title":"Dev. Biol."}],"container-title":["Mechanisms of Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925477398000471?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925477398000471?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T19:14:51Z","timestamp":1620846891000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925477398000471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,5]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1998,5]]}},"alternative-id":["S0925477398000471"],"URL":"https:\/\/doi.org\/10.1016\/s0925-4773(98)00047-1","relation":{},"ISSN":["0925-4773"],"issn-type":[{"value":"0925-4773","type":"print"}],"subject":[],"published":{"date-parts":[[1998,5]]}}}