{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T15:34:17Z","timestamp":1759073657851,"version":"3.44.0"},"reference-count":129,"publisher":"Elsevier","isbn-type":[{"type":"print","value":"9780323851602"}],"license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022]]},"DOI":"10.1016\/b978-0-323-85160-2.00006-8","type":"book-chapter","created":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T06:19:21Z","timestamp":1642745961000},"page":"55-86","source":"Crossref","is-referenced-by-count":2,"title":["Anticancer drugs in the environment: environmental levels and technological challenges"],"prefix":"10.1016","author":[{"given":"Jo\u00e3o Vasco","family":"Valente","sequence":"first","affiliation":[]},{"given":"Susana","family":"Coelho","sequence":"additional","affiliation":[]},{"given":"M. Ramiro","family":"Pastorinho","sequence":"additional","affiliation":[]},{"given":"Ana Catarina","family":"A. Sousa","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib1","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.scitotenv.2019.07.247","article-title":"Photocatalytic degradation of cyclophosphamide and ifosfamide: Effects of wastewater matrix, transformation products and in silico toxicity prediction","volume":"692","author":"Osawa","year":"2019","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib2","first-page":"1","article-title":"Persulphate activation under UV radiation for cyclophosphamide degradation and mineralisation in aqueous solution","author":"Akbari","year":"2020","journal-title":"International Journal of Environmental Analytical Chemistry"},{"issue":"16","key":"10.1016\/B978-0-323-85160-2.00006-8_bib3","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1080\/10643389.2011.569872","article-title":"Aerobic biodegradation of phenols: A comprehensive review","volume":"42","author":"Al-Khalid","year":"2012","journal-title":"Critical Reviews in Environmental Science and Technology"},{"issue":"11","key":"10.1016\/B978-0-323-85160-2.00006-8_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/app8112043","article-title":"Distribution of anticancer drugs in river waters and sediments of the Yodo river basin, Japan","volume":"8","author":"Azuma","year":"2018","journal-title":"Applied Sciences"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib5","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.scitotenv.2018.11.433","article-title":"Environmental fate of pharmaceutical compounds and antimicrobial-resistant bacteria in hospital effluents, and contributions to pollutant loads in the surface waters in Japan","volume":"657","author":"Azuma","year":"2019","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib6","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1016\/j.cej.2017.11.105","article-title":"Electro-oxidation of cytostatic drugs: Experimental and theoretical identification of by-products and evaluation of ecotoxicological effects","volume":"334","author":"Bar\u0131\u015f\u00e7\u0131","year":"2018","journal-title":"Chemical Engineering Journal"},{"issue":"12","key":"10.1016\/B978-0-323-85160-2.00006-8_bib7","first-page":"4129","article-title":"Cyclophosphamide neutralization in wastewaters using an asymmetric current density electrochemical microreactor","volume":"70","author":"Barzan","year":"2019","journal-title":"Revista de Chimie"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib8","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.scitotenv.2017.08.279","article-title":"Occurrence, distribution and environmental risk of pharmaceutically active compounds (PhACs) in coastal and ocean waters from the Gulf of Cadiz (SW Spain)","volume":"612","author":"Biel-Maeso","year":"2018","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib33","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.seppur.2016.06.012","article-title":"Bi-B-TiO2-based photocatalytic decomposition of cytostatic drugs under simulated sunlight treatments","volume":"169","author":"Borzyszkowska","year":"2016","journal-title":"Separation and Purification Technology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib9","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.scitotenv.2014.05.143","article-title":"The SOLUTIONS project: Challenges and responses for present and future emerging pollutants in land and water resources management","volume":"503\u2013504","author":"Brack","year":"2015","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib131","doi-asserted-by":"crossref","unstructured":"Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R.L., Torre, L.A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394\u2013424.","DOI":"10.3322\/caac.21492"},{"issue":"23","key":"10.1016\/B978-0-323-85160-2.00006-8_bib10","doi-asserted-by":"crossref","first-page":"7242","DOI":"10.1021\/es0609405","article-title":"Occurrence and fate of the cytostatic drugs cyclophosphamide and ifosfamide in wastewater and surface waters","volume":"40","author":"Buerge","year":"2006","journal-title":"Environmental Science & Technology"},{"issue":"7","key":"10.1016\/B978-0-323-85160-2.00006-8_bib11","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1021\/es020158e","article-title":"Strategic survey of therapeutic drugs in the rivers Po and Lambro in Northern Italy","volume":"37","author":"Calamari","year":"2003","journal-title":"Environmental Science & Technology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib12","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.jenvman.2017.07.052","article-title":"Stropharia rugosoannulata and Gymnopilus luteofolius: Promising fungal species for pharmaceutical biodegradation in contaminated water","volume":"207","author":"Castellet-Rovira","year":"2018","journal-title":"Journal of Environmental Management"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib13","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.scitotenv.2015.04.109","article-title":"Occurrence of cyclophosphamide and ifosfamide in aqueous environment and their removal by biological and abiotic wastewater treatment processes","volume":"527\u2013528","author":"\u010cesen","year":"2015","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib14","doi-asserted-by":"crossref","first-page":"126866","DOI":"10.1016\/j.cej.2020.126866","article-title":"Photolytic and photocatalytic degradation of antineoplastic drug irinotecan. Kinetic study, identification of transformation products and toxicity evaluation","volume":"405","author":"Chatzimpaloglou","year":"2021","journal-title":"Chemical Engineering Journal"},{"issue":"4","key":"10.1016\/B978-0-323-85160-2.00006-8_bib15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s11783-019-1143-2","article-title":"Ozonation of the 5-fluorouracil anticancer drug and its prodrug capecitabine: Reaction kinetics, oxidation mechanisms, and residual toxicity","volume":"13","author":"Chen","year":"2019","journal-title":"Frontiers of Environmental Science & Engineering"},{"issue":"3","key":"10.1016\/B978-0-323-85160-2.00006-8_bib16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.37358\/RC.20.3.7984","article-title":"Doxorubicin depuration in oncological wastewaters using an electrochemical method","volume":"71","author":"Crisnic","year":"2020","journal-title":"Revista de Chimie"},{"issue":"4","key":"10.1016\/B978-0-323-85160-2.00006-8_bib17","doi-asserted-by":"crossref","first-page":"347","DOI":"10.37358\/RC.20.4.8074","article-title":"Ag-TiO2 assisted photocatalytic degradation of cytostatic drug cyclophosphamide under UV-VIS light","volume":"71","author":"Cristea Ionut","year":"2020","journal-title":"Revista de Chimie"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib18","doi-asserted-by":"crossref","first-page":"122330","DOI":"10.1016\/j.jhazmat.2020.122330","article-title":"Predicted concentrations of anticancer drugs in the aquatic environment: What should we monitor and where should we treat?","volume":"392","author":"Crist\u00f3v\u00e3o","year":"2020","journal-title":"Journal of Hazardous Materials"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib19","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.seppur.2019.05.016","article-title":"Treatment of anticancer drugs in hospital and wastewater effluents using nanofiltration","volume":"224","author":"Crist\u00f3v\u00e3o","year":"2019","journal-title":"Separation and Purification Technology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib20","series-title":"Water supply and wastewater disposal designing, construction, operation and monitoring","first-page":"53","article-title":"Occurrence of cytostatic drugs in hospital wastewater","author":"Czerwi\u0144ski","year":"2020"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib21","doi-asserted-by":"crossref","first-page":"135568","DOI":"10.1016\/j.scitotenv.2019.135568","article-title":"Pharmaceuticals residues and xenobiotics contaminants: Occurrence, analytical techniques and sustainable alternatives for wastewater treatment","volume":"705","author":"de Oliveira","year":"2020","journal-title":"The Science of the Total Environment"},{"issue":"6","key":"10.1016\/B978-0-323-85160-2.00006-8_bib22","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.ijheh.2011.08.002","article-title":"Emerging pollutants in wastewater: A review of the literature","volume":"214","author":"Deblonde","year":"2011","journal-title":"International Journal of Hygiene and Environmental Health"},{"issue":"6","key":"10.1016\/B978-0-323-85160-2.00006-8_bib23","doi-asserted-by":"crossref","first-page":"4395","DOI":"10.1016\/j.biortech.2010.12.107","article-title":"Cytotoxicity micropollutant removal in a crossflow membrane bioreactor","volume":"102","author":"Delgado","year":"2011","journal-title":"Bioresource Technology"},{"issue":"8","key":"10.1016\/B978-0-323-85160-2.00006-8_bib24","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1080\/07388551.2017.1303804","article-title":"Biotherapeutic potential and mechanisms of action of colchicine","volume":"37","author":"Dubey","year":"2017","journal-title":"Critical Reviews in Biotechnology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib25","doi-asserted-by":"crossref","first-page":"124990","DOI":"10.1016\/j.chemosphere.2019.124990","article-title":"Simultaneous degradation of the anticancer drugs 5-fluorouracil and cyclophosphamide using a heterogeneous photo-Fenton process based on copper-containing magnetites (Fe3-xCuxO4)","volume":"241","author":"Em\u00eddio","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib26","unstructured":"European Commission. (2016). Communication from the commission to the European parliament, the council, the European economic and social committee and the committee of the regions. A European agenda for the collaborative economy."},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib27","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.cej.2015.04.071","article-title":"Electrodegradation of ifosfamide and cyclophosphamide at BDD electrode: Decomposition pathway and its kinetics","volume":"276","author":"Fabia\u0144ska","year":"2015","journal-title":"Chemical Engineering Journal"},{"issue":"3","key":"10.1016\/B978-0-323-85160-2.00006-8_bib28","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1747-6593.2009.00169.x","article-title":"Cyclophosphamide degradation by advanced oxidation processes","volume":"24","author":"Fern\u00e1ndez","year":"2010","journal-title":"Water and Environment Journal"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib29","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.chemosphere.2015.03.051","article-title":"Non conventional biological treatment based on Trametes versicolor for the elimination of recalcitrant anticancer drugs in hospital wastewater","volume":"136","author":"Ferrando-Climent","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib30","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.chemosphere.2016.10.057","article-title":"Elimination study of the chemotherapy drug tamoxifen by different advanced oxidation processes: Transformation products and toxicity assessment","volume":"168","author":"Ferrando-Climent","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib31","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.scitotenv.2016.02.202","article-title":"Ozonation of hospital raw wastewaters for cytostatic compounds removal. Kinetic modelling and economic assessment of the process","volume":"556","author":"Ferre-Aracil","year":"2016","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib32","doi-asserted-by":"crossref","first-page":"114252","DOI":"10.1016\/j.jelechem.2020.114252","article-title":"Effective degradation of the antineoplastic doxorubicin by electrochemical oxidation on boron doped diamond","volume":"870","author":"Ferreira Garcia","year":"2020","journal-title":"Journal of Electroanalytical Chemistry"},{"issue":"7","key":"10.1016\/B978-0-323-85160-2.00006-8_bib34","doi-asserted-by":"crossref","first-page":"6492","DOI":"10.1007\/s11356-016-8337-y","article-title":"Determination of cytostatic drugs in Bes\u00f2s River (NE Spain) and comparison with predicted environmental concentrations","volume":"24","author":"Franquet-Griell","year":"2017","journal-title":"Environmental Science and Pollution Research International"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib35","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.jhazmat.2016.06.057","article-title":"Biological and photochemical degradation of cytostatic drugs under laboratory conditions","volume":"323","author":"Franquet-Griell","year":"2017","journal-title":"Journal of Hazardous Materials"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib36","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.chemosphere.2017.05.051","article-title":"Development of a macroporous ceramic passive sampler for the monitoring of cytostatic drugs in water","volume":"182","author":"Franquet-Griell","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib128","article-title":"Effective degradation of the antineoplastic doxorubicin by electrochemical oxidation on boron doped diamond","volume":"870","author":"Garcia","year":"2020","journal-title":"Journal of Electroanalytical Chemistry"},{"issue":"11","key":"10.1016\/B978-0-323-85160-2.00006-8_bib37","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.chemosphere.2010.03.032","article-title":"Oxidation kinetics of cyclophosphamide and methotrexate by ozone in drinking water","volume":"79","author":"Garcia-Ac","year":"2010","journal-title":"Chemosphere"},{"issue":"48","key":"10.1016\/B978-0-323-85160-2.00006-8_bib38","doi-asserted-by":"crossref","first-page":"8518","DOI":"10.1016\/j.chroma.2009.10.015","article-title":"On-line solid-phase extraction of large-volume injections coupled to liquid chromatography-tandem mass spectrometry for the quantitation and confirmation of 14 selected trace organic contaminants in drinking and surface water","volume":"1216","author":"Garcia-Ac","year":"2009","journal-title":"Journal of Chromatography. A"},{"issue":"3","key":"10.1016\/B978-0-323-85160-2.00006-8_bib39","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1080\/10807039.2017.1400372","article-title":"Platinum cytotoxic drugs in the municipal wastewater and drinking water, a validation method and health risk assessment","volume":"24","author":"Ghafuri","year":"2018","journal-title":"Human and Ecological Risk Assessment: An International Journal"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib40","doi-asserted-by":"crossref","first-page":"471","DOI":"10.18178\/ijesd.2020.11.10.1292","article-title":"Methotrexate degradation by UV-C and UV-C\/TiO2 processes with and without H2O2 addition on pilot reactors","volume":"11","author":"Gonz\u00e1lez-Burciaga","year":"2020","journal-title":"International Journal of Environmental Science and Development"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib41","doi-asserted-by":"crossref","first-page":"105236","DOI":"10.1016\/j.envint.2019.105236","article-title":"New insights on cytostatic drug risk assessment in aquatic environments based on measured concentrations in surface waters","volume":"133","author":"Gouveia","year":"2019","journal-title":"Environment International"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib42","doi-asserted-by":"crossref","first-page":"139995","DOI":"10.1016\/j.scitotenv.2020.139995","article-title":"Liquid-liquid extraction as a simple tool to quickly quantify fourteen cytostatics in urban wastewaters and access their impact in aquatic biota","volume":"740","author":"Gouveia","year":"2020","journal-title":"The Science of the Total Environment"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib43","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1007\/s11356-016-7827-2","article-title":"Degradation of the cytostatic 5-fluorouracil in water by Fenton and photo-assisted oxidation processes","volume":"24","author":"Governo","year":"2017","journal-title":"Environmental Science and Pollution Research"},{"issue":"94","key":"10.1016\/B978-0-323-85160-2.00006-8_bib44","doi-asserted-by":"crossref","first-page":"76772","DOI":"10.1039\/C5RA17315A","article-title":"Evaluation of the aquatic toxic effect varied during the degradation of capecitabine under the environmental abiotic and biotic processes","volume":"5","author":"Guo","year":"2015","journal-title":"RSC Advances"},{"issue":"2","key":"10.1016\/B978-0-323-85160-2.00006-8_bib45","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s004200050124","article-title":"Chemical degradation of wastes of antineoplastic agents: Cyclophosphamide, ifosfamide and melphalan","volume":"69","author":"Hansel","year":"1996","journal-title":"International Archives of Occupational and Environmental Health"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib46","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.biortech.2014.08.036","article-title":"Evaluation of the efficiency of Trametes hirsuta for the removal of multiple pharmaceutical compounds under low concentrations relevant to the environment","volume":"171","author":"Haroune","year":"2014","journal-title":"Bioresource Technology"},{"issue":"3","key":"10.1016\/B978-0-323-85160-2.00006-8_bib47","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/01919510801907722","article-title":"Ozonation of cisplatin in aqueous solution at pH 9","volume":"30","author":"Hern\u00e1ndez","year":"2008","journal-title":"Ozone: Science & Engineering"},{"issue":"8","key":"10.1016\/B978-0-323-85160-2.00006-8_bib48","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/j.chemosphere.2005.01.024","article-title":"Inactivation of antineoplastics in clinical wastewater by electrolysis","volume":"60","author":"Hirose","year":"2005","journal-title":"Chemosphere"},{"issue":"17","key":"10.1016\/B978-0-323-85160-2.00006-8_bib49","doi-asserted-by":"crossref","first-page":"20807","DOI":"10.1007\/s11356-020-08500-1","article-title":"Radiolytic degradation of anticancer drug capecitabine in aqueous solution: Kinetics, reaction mechanism, and toxicity evaluation","volume":"27","author":"Huo","year":"2020","journal-title":"Environmental Science and Pollution Research"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib50","unstructured":"IRODaT. (2019). Worldwide actual deceased organ donors. <https:\/\/www.irodat.org\/?p=database&c=0#data>. Accessed 22.02.21."},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib51","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.envpol.2016.10.039","article-title":"Chemical and toxicological characterisation of anticancer drugs in hospital and municipal wastewaters from Slovenia and Spain","volume":"219","author":"Isidori","year":"2016","journal-title":"Environmental Pollution"},{"issue":"5","key":"10.1016\/B978-0-323-85160-2.00006-8_bib52","doi-asserted-by":"crossref","first-page":"103351","DOI":"10.1016\/j.jece.2019.103351","article-title":"Coupling of nanofiltration and UV, UV\/TiO2 and UV\/H2O2 processes for the removal of anti-cancer drugs from real secondary wastewater effluent","volume":"7","author":"Janssens","year":"2019","journal-title":"Journal of Environmental Chemical Engineering"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib53","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jhydrol.2007.09.054","article-title":"Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study","volume":"348","author":"Johnson","year":"2008","journal-title":"Journal of Hydrology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib54","doi-asserted-by":"crossref","first-page":"124520","DOI":"10.1016\/j.jhazmat.2020.124520","article-title":"Laccase as an efficacious approach to remove anticancer drugs: A study of doxorubicin degradation, kinetic parameters, and toxicity assessment","volume":"409","author":"Kelbert","year":"2020","journal-title":"Journal of Hazardous Materials"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib55","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ecoenv.2011.11.028","article-title":"Application of electrolysis for detoxification of an antineoplastic in urine","volume":"78","author":"Kobayashi","year":"2012","journal-title":"Ecotoxicology and Environmental Safety"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib56","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.scitotenv.2016.08.208","article-title":"Photocatalytical removal of fluorouracil using TiO2-P25 and N\/S doped TiO2 catalysts: A kinetic and mechanistic study","volume":"578","author":"Koltsakidou","year":"2017","journal-title":"Science of the Total Environment"},{"issue":"7","key":"10.1016\/B978-0-323-85160-2.00006-8_bib57","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.trac.2011.04.007","article-title":"Occurrence, fate and determination of cytostatic pharmaceuticals in the environment","volume":"30","author":"Kosjek","year":"2011","journal-title":"TrAC Trends in Analytical Chemistry"},{"issue":"14","key":"10.1016\/B978-0-323-85160-2.00006-8_bib58","doi-asserted-by":"crossref","first-page":"7899","DOI":"10.1021\/es400708w","article-title":"Elimination of micropollutants during post-treatment of hospital wastewater with powdered activated carbon, ozone, and UV","volume":"47","author":"Kovalova","year":"2013","journal-title":"Environmental Science & Technology"},{"issue":"4","key":"10.1016\/B978-0-323-85160-2.00006-8_bib59","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/s12291-016-0557-x","article-title":"Liquid\u2013liquid extraction and solid phase extraction for urinary organic acids: A comparative study from a resource constraint setting","volume":"31","author":"Kumari","year":"2016","journal-title":"Indian Journal of Clinical Biochemistry"},{"issue":"15","key":"10.1016\/B978-0-323-85160-2.00006-8_bib60","doi-asserted-by":"crossref","first-page":"14791","DOI":"10.1007\/s11356-014-3902-8","article-title":"Antineoplastic compounds in the environment\u2014Substances of special concern","volume":"23","author":"K\u00fcmmerer","year":"2016","journal-title":"Environmental Science and Pollution Research"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib61","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.jhazmat.2015.01.045","article-title":"TiO2 photocatalytic degradation and transformation of oxazaphosphorine drugs in an aqueous environment","volume":"287","author":"Lai","year":"2015","journal-title":"Journal of Hazardous Materials"},{"issue":"6","key":"10.1016\/B978-0-323-85160-2.00006-8_bib62","first-page":"189","article-title":"Degradation of toxic dyes: A review","volume":"3","author":"Lavanya","year":"2014","journal-title":"International Journal of Current Microbiology and Applied Sciences"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib63","doi-asserted-by":"crossref","first-page":"128817","DOI":"10.1016\/j.chemosphere.2020.128817","article-title":"Degradation of cyclophosphamide during UV\/chlorine reaction: Kinetics, byproducts, and their toxicity","volume":"268","author":"Lee","year":"2021","journal-title":"Chemosphere"},{"issue":"11","key":"10.1016\/B978-0-323-85160-2.00006-8_bib64","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.2166\/wst.2011.079","article-title":"Removal of pharmaceuticals using combination of UV\/H2O2\/O3 advanced oxidation process","volume":"64","author":"Lester","year":"2011","journal-title":"Water Science and Technology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib65","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.jhazmat.2015.10.035","article-title":"Removal of polycyclic synthetic musks and antineoplastic drugs in ozonated wastewater: Quantitation based on the data of differential spectroscopy","volume":"304","author":"Li","year":"2016","journal-title":"Journal of Hazardous Materials"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib66","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.mee.2014.03.045","article-title":"Optical properties of ordered dot-on-plate nano-sandwich arrays","volume":"127","author":"Li","year":"2014","journal-title":"Microelectronic Engineering"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib67","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1007\/s11356-014-3288-7","article-title":"Removal of antineoplastic drugs cyclophosphamide, ifosfamide, and 5-fluorouracil and a vasodilator drug pentoxifylline from wastewaters by ozonation","volume":"22","author":"Lin","year":"2015","journal-title":"Environmental Science and Pollution Research"},{"issue":"9","key":"10.1016\/B978-0-323-85160-2.00006-8_bib68","doi-asserted-by":"crossref","first-page":"4104","DOI":"10.1021\/es304976q","article-title":"Phototransformation determines the fate of 5-fluorouracil and cyclophosphamide in natural surface waters","volume":"47","author":"Lin","year":"2013","journal-title":"Environmental Science & Technology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib69","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.watres.2013.10.011","article-title":"Photocatalytic oxidation of 5-fluorouracil and cyclophosphamide via UV\/TiO2 in an aqueous environment","volume":"48","author":"Lin","year":"2014","journal-title":"Water Research"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib70","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.envpol.2012.11.022","article-title":"Occurrence of 95 pharmaceuticals and transformation products in urban groundwaters underlying the metropolis of Barcelona, Spain","volume":"174","author":"L\u00f3pez-Serna","year":"2013","journal-title":"Environmental Pollution"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib71","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.chemosphere.2015.07.069","article-title":"Removal of the anti-cancer drug methotrexate from water by advanced oxidation processes: Aerobic biodegradation and toxicity studies after treatment","volume":"141","author":"Lutterbeck","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib72","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.chemosphere.2014.08.076","article-title":"Photodegradation of the antineoplastic cyclophosphamide: A comparative study of the efficiencies of UV\/H2O2, UV\/Fe2+\/H2O2 and UV\/TiO2 processes","volume":"120","author":"Lutterbeck","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib73","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.scitotenv.2015.04.111","article-title":"Degradation of 5-FU by means of advanced (photo)oxidation processes: UV\/H2O2, UV\/Fe2+\/H2O2 and UV\/TiO2\u2014Comparison of transformation products, ready biodegradability and toxicity","volume":"527\u2013528","author":"Lutterbeck","year":"2015","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib74","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.envpol.2015.10.016","article-title":"Degradation of cyclophosphamide and 5-fluorouracil by UV and simulated sunlight treatments: Assessment of the enhancement of the biodegradability and toxicity","volume":"208","author":"Lutterbeck","year":"2016","journal-title":"Environmental Pollution"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib75","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.chemosphere.2006.05.051","article-title":"Fate of 5-fluorouracil, doxorubicin, epirubicin, and daunorubicin in hospital wastewater and their elimination by activated sludge and treatment in a membrane-bio-reactor system","volume":"66","author":"Mahnik","year":"2007","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib76","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.watres.2019.04.010","article-title":"Removal of 5-fluorouracil by solar-driven photoelectrocatalytic oxidation using Ti\/TiO2(NT) photoelectrodes","volume":"157","author":"Mazierski","year":"2019","journal-title":"Water Research"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib77","unstructured":"Ministry of Health Labour and Welfare Japan. (2013). Pharmaceutical industry vision (in Japanese). (pp. 1\u201376)."},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib78","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.scitotenv.2014.07.101","article-title":"Cytostatic drugs and metabolites in municipal and hospital wastewaters in Spain: Filtration, occurrence, and environmental risk","volume":"497\u2013498","author":"Negreira","year":"2014","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib79","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.scitotenv.2017.05.115","article-title":"Cytotoxicity and genotoxicity of anticancer drug residues and their mixtures in experimental model with zebrafish liver cells","volume":"601\u2013602","author":"Novak","year":"2017","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib80","series-title":"Advances in chemistry research","article-title":"Understanding the efficiency of electrochemical oxidation in toxicity removal","author":"Nunes","year":"2019"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib81","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.chemosphere.2018.03.050","article-title":"Electrochemical degradation of 5-FU using a flow reactor with BDD electrode: Comparison of two electrochemical systems","volume":"201","author":"Ochoa-Chavez","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib82","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.cej.2015.09.109","article-title":"Pt\u2013TiO2-assisted photocatalytic degradation of the cytostatic drugs ifosfamide and cyclophosphamide under artificial sunlight","volume":"285","author":"Ofiarska","year":"2016","journal-title":"Chemical Engineering Journal"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib83","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.chemosphere.2017.09.129","article-title":"A case study to identify priority cytostatic contaminants in hospital effluents","volume":"190","author":"Olalla","year":"2018","journal-title":"Chemosphere"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib84","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s00253-019-10229-y","article-title":"Potential of enzymatic process as an innovative technology to remove anticancer drugs in wastewater","volume":"104","author":"Pereira","year":"2020","journal-title":"Applied Microbiology and Biotechnology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib85","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1590\/S0100-40422012000500019","article-title":"Desenvolvimento de metodologia para avaliar remo\u00e7\u00e3o de estrog\u00eanios em esta\u00e7\u00f5es de tratamento de esgotos","volume":"35","author":"Pessoa","year":"2012","journal-title":"Qu\u00edmica Nova"},{"issue":"14","key":"10.1016\/B978-0-323-85160-2.00006-8_bib86","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1080\/10643389.2017.1370990","article-title":"Removal of cytostatic drugs by AOPs: A review of applied processes in the context of green technology","volume":"47","author":"Pieczy\u0144ska","year":"2017","journal-title":"Critical Reviews in Environmental Science and Technology"},{"issue":"23","key":"10.1016\/B978-0-323-85160-2.00006-8_bib87","doi-asserted-by":"crossref","first-page":"4356","DOI":"10.3390\/molecules24234356","article-title":"Insights into mechanisms of electrochemical drug degradation in their mixtures in the split-flow reactor","volume":"24","author":"Pieczy\u0144ska","year":"2019","journal-title":"Molecules (Basel, Switzerland)"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib88","unstructured":"Pruijn, F., DeWitte, R. (2004). A practical approach to improving drug transport in tumors. Current Drug Discovery. (pp. 29\u201332)."},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib89","doi-asserted-by":"crossref","first-page":"128371","DOI":"10.1016\/j.chemosphere.2020.128371","article-title":"Synthesis and catalytic utilization of bimetallic systems for wastewater remediation: A review","volume":"262","author":"Quiton","year":"2021","journal-title":"Chemosphere"},{"issue":"11","key":"10.1016\/B978-0-323-85160-2.00006-8_bib90","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1080\/00032710600755793","article-title":"Sources of errors associated with the determination of PAH and PCB analytes in water samples","volume":"39","author":"Rawa-Adkonis","year":"2006","journal-title":"Analytical Letters"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib91","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.scitotenv.2005.04.031","article-title":"The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment","volume":"356","author":"Roberts","year":"2006","journal-title":"Science of the Total Environment"},{"issue":"5","key":"10.1016\/B978-0-323-85160-2.00006-8_bib92","doi-asserted-by":"crossref","first-page":"478","DOI":"10.3390\/catal9050478","article-title":"Wastewater treatment by catalytic wet peroxidation using nano gold-based catalysts: A review","volume":"9","author":"Rodrigues","year":"2019","journal-title":"Catalysts"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib93","doi-asserted-by":"crossref","first-page":"141990","DOI":"10.1016\/j.scitotenv.2020.141990","article-title":"Treatment technologies for emerging contaminants in wastewater treatment plants: A review","volume":"753","author":"Rout","year":"2021","journal-title":"The Science of the Total Environment"},{"issue":"2","key":"10.1016\/B978-0-323-85160-2.00006-8_bib94","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s00216-008-2498-6","article-title":"Comparison of extraction efficiencies and LC\u2013MS\u2013MS matrix effects using LLE and SPE methods for 19 antipsychotics in human blood","volume":"393","author":"Saar","year":"2009","journal-title":"Analytical and Bioanalytical Chemistry"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib95","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jchromb.2019.02.018","article-title":"Simultaneous and systematic analysis of cytostatic drugs in wastewater samples by ultra-high performance liquid chromatography tandem mass spectrometry","volume":"1110\u20131111","author":"Santana-Viera","year":"2019","journal-title":"Journal of Chromatography B"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib96","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.trac.2015.08.016","article-title":"Cytostatic drugs in environmental samples: an update on the extraction and determination procedures","volume":"80","author":"Santana-Viera","year":"2016","journal-title":"TrAC Trends in Analytical Chemistry"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib97","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.scitotenv.2018.07.232","article-title":"Development of an analytical methodology for the analysis of priority cytostatics in water","volume":"645","author":"Santos","year":"2018","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib98","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1016\/j.chemosphere.2017.06.102","article-title":"Anticancer drugs in Portuguese surface waters \u2013 Estimation of concentrations and identification of potentially priority drugs","volume":"184","author":"Santos","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib99","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.bej.2016.07.001","article-title":"Elimination of an anticancer drug (cyclophosphamide) by a membrane bioreactor: Comprehensive study of mechanisms","volume":"114","author":"Seira","year":"2016","journal-title":"Biochemical Engineering Journal"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib100","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.watres.2018.07.035","article-title":"Cytostatic drug removal using electrochemical oxidation with BDD electrode: Degradation pathway and toxicity","volume":"144","author":"Siedlecka","year":"2018","journal-title":"Water Research"},{"issue":"5","key":"10.1016\/B978-0-323-85160-2.00006-8_bib101","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1016\/j.envpol.2009.10.036","article-title":"Occurrence and fate of pharmaceuticals in wastewater treatment plants and rivers in Korea","volume":"158","author":"Sim","year":"2010","journal-title":"Environmental Pollution"},{"issue":"6","key":"10.1016\/B978-0-323-85160-2.00006-8_bib102","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1080\/07388551.2017.1417234","article-title":"Laccase grafted membranes for advanced water filtration systems: A green approach to water purification technology","volume":"38","author":"Singh","year":"2018","journal-title":"Critical Reviews in Biotechnology"},{"issue":"11","key":"10.1016\/B978-0-323-85160-2.00006-8_bib103","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1080\/10934529.2012.680414","article-title":"A comparison between ozonolysis and sonolysis\/ozonolysis treatments for the degradation of the cytostatic drugs methotrexate and doxorubicin: Kinetic and efficiency approaches","volume":"47","author":"Somensi","year":"2012","journal-title":"Journal of Environmental Science and Health, Part A"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib126","doi-asserted-by":"crossref","unstructured":"Souza, D.M., Reichert, J.F., & Martins, A.F. (2018). A simultaneous determination of anti-cancer drugs in hospital effluent by DLLME HPLC-FLD, together with a risk assessment. Chemosphere, 201, 178\u2013188.","DOI":"10.1016\/j.chemosphere.2018.02.164"},{"issue":"5","key":"10.1016\/B978-0-323-85160-2.00006-8_bib104","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12918-017-0464-7","article-title":"A systematic analysis of FDA-approved anticancer drugs","volume":"11","author":"Sun","year":"2017","journal-title":"BMC Systems Biology"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib105","doi-asserted-by":"crossref","first-page":"127489","DOI":"10.1016\/j.cej.2020.127489","article-title":"Degradation of anticancer drug capecitabine in aquatic media by three advanced oxidation processes: Mechanisms, toxicity changes and energy cost evaluation","volume":"413","author":"Tang","year":"2020","journal-title":"Chemical Engineering Journal"},{"issue":"7","key":"10.1016\/B978-0-323-85160-2.00006-8_bib106","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1080\/03067310500291502","article-title":"Trace determination of tamoxifen and 5-fluorouracil in hospital and urban wastewaters","volume":"86","author":"Tauxe-Wuersch","year":"2006","journal-title":"International Journal of Environmental Analytical Chemistry"},{"year":"2017","series-title":"The United Nations world water development report, 2017: Wastewater: the untapped resource","author":"United Nations World Water Assessment Programme","key":"10.1016\/B978-0-323-85160-2.00006-8_bib130"},{"issue":"10","key":"10.1016\/B978-0-323-85160-2.00006-8_bib107","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/j.chemosphere.2011.05.014","article-title":"Detection of pharmaceutically active compounds in the rivers and tap water of the Madrid Region (Spain) and potential ecotoxicological risk","volume":"84","author":"Valc\u00e1rcel","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib108","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.scitotenv.2015.02.020","article-title":"What have we learned from worldwide experiences on the management and treatment of hospital effluent?\u2014An overview and a discussion on perspectives","volume":"514","author":"Verlicchi","year":"2015","journal-title":"Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib109","series-title":"Fate and effects of anticancer drugs in the environment","first-page":"221","article-title":"Occurrence of cytostatics in different water compartments","author":"Verlicchi","year":"2020"},{"issue":"15","key":"10.1016\/B978-0-323-85160-2.00006-8_bib110","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1016\/j.watres.2007.05.022","article-title":"Influence of electrostatic interactions on the rejection with NF and assessment of the removal efficiency during NF\/GAC treatment of pharmaceutically active compounds in surface water","volume":"41","author":"Verliefde","year":"2007","journal-title":"Water Research"},{"issue":"17","key":"10.1016\/B978-0-323-85160-2.00006-8_bib111","doi-asserted-by":"crossref","first-page":"4115","DOI":"10.1016\/j.watres.2009.06.007","article-title":"Cyclophosphamide removal from water by nanofiltration and reverse osmosis membrane","volume":"43","author":"Wang","year":"2009","journal-title":"Water Research"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib112","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.cej.2018.01.125","article-title":"Removal of cytostatic drugs from wastewater by an anaerobic osmotic membrane bioreactor","volume":"339","author":"Wang","year":"2018","journal-title":"Chemical Engineering Journal"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib113","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.cej.2018.07.162","article-title":"Removal of doxorubicin hydrochloride using Fe3O4 nanoparticles synthesized by Euphorbia cochinchinensis extract","volume":"353","author":"Weng","year":"2018","journal-title":"Chemical Engineering Journal"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib114","series-title":"Guidelines for ATC classification and DDD assignment","first-page":"20","author":"WHO Collaborating Centre for Drug Statistics Methodology","year":"2021"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib115","doi-asserted-by":"crossref","first-page":"111932","DOI":"10.1016\/j.jphotochem.2019.111932","article-title":"Photocatalytic activity of solvothermal prepared BiOClBr with imidazolium ionic liquids as a halogen sources in cytostatic drugs removal","volume":"382","author":"Wilczewska","year":"2019","journal-title":"Journal of Photochemistry and Photobiology A: Chemistry"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib116","doi-asserted-by":"crossref","first-page":"117601","DOI":"10.1016\/j.seppur.2020.117601","article-title":"Application of BiOClnBrm photocatalyst to cytostatic drugs removal from water; mechanism and toxicity assessment","volume":"254","author":"Wilczewska","year":"2021","journal-title":"Separation and Purification Technology"},{"issue":"5","key":"10.1016\/B978-0-323-85160-2.00006-8_bib117","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1002\/etc.4687","article-title":"Antineoplastic agents: Environmental prevalence and adverse outcomes in aquatic organisms","volume":"39","author":"Wormington","year":"2020","journal-title":"Environmental Toxicology and Chemistry"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib118","doi-asserted-by":"crossref","first-page":"125058","DOI":"10.1016\/j.chemosphere.2019.125058","article-title":"Insights into the degradation and detoxication mechanisms of aqueous capecitabine in electrochemical oxidation process","volume":"241","author":"Xu","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib119","doi-asserted-by":"crossref","first-page":"128285","DOI":"10.1016\/j.chemosphere.2020.128285","article-title":"Threat and sustainable technological solution for antineoplastic drugs pollution: Review on a persisting global issue","volume":"263","author":"Yadav","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib120","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.scitotenv.2012.12.061","article-title":"Removal of cytostatic drugs from aquatic environment: A review","volume":"445\u2013446","author":"Zhang","year":"2013","journal-title":"The Science of the Total Environment"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib121","series-title":"Fate and effects of anticancer drugs in the environment","first-page":"245","article-title":"Photodegradation of cytostatic drugs in low-pressure UV photoreactor through direct and indirect pathways","author":"Zhang","year":"2020"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib122","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.jece.2017.01.013","article-title":"Degradation of cyclophosphamide and 5-fluorouracil in water using UV and UV\/H2O2: Kinetics investigation, pathways and energetic analysis","volume":"5","author":"Zhang","year":"2017","journal-title":"Journal of Environmental Chemical Engineering"},{"key":"10.1016\/B978-0-323-85160-2.00006-8_bib123","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jhazmat.2016.11.016","article-title":"Direct and indirect photodegradation pathways of cytostatic drugs under UV germicidal irradiation: Process kinetics and influences of water matrix species and oxidant dosing","volume":"324","author":"Zhang","year":"2017","journal-title":"Journal of Hazardous Materials"},{"issue":"1","key":"10.1016\/B978-0-323-85160-2.00006-8_bib124","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.chroma.2007.03.105","article-title":"Simultaneous determination of various pharmaceutical compounds in water by solid-phase extraction\u2013liquid chromatography\u2013tandem mass spectrometry","volume":"1154","author":"Zhang","year":"2007","journal-title":"Journal of Chromatography. A"},{"issue":"2","key":"10.1016\/B978-0-323-85160-2.00006-8_bib125","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.jhazmat.2008.11.070","article-title":"Pharmaceutical residues in wastewater treatment works effluents and their impact on receiving river water","volume":"166","author":"Zhou","year":"2009","journal-title":"Journal of Hazardous Materials"}],"container-title":["Emerging Contaminants in the Environment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780323851602000068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:B9780323851602000068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T05:30:04Z","timestamp":1758691804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/B9780323851602000068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"ISBN":["9780323851602"],"references-count":129,"URL":"https:\/\/doi.org\/10.1016\/b978-0-323-85160-2.00006-8","relation":{},"subject":[],"published":{"date-parts":[[2022]]}}}