{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:49:01Z","timestamp":1775472541429,"version":"3.50.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T00:00:00Z","timestamp":1764892800000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["NMBP-21-2020"],"award-info":[{"award-number":["NMBP-21-2020"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["UID\/50011\/2025"],"award-info":[{"award-number":["UID\/50011\/2025"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Foundation for Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018693","name":"H2020","doi-asserted-by":"publisher","award":["953169"],"award-info":[{"award-number":["953169"]}],"id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Acta Biomaterialia"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.actbio.2025.12.014","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T16:26:16Z","timestamp":1764951976000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Enhancing bioactivity of calcium-phosphate cement-based 3D printed scaffolds with human platelet lysates: in vitro and in vivo validation"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7136-984X","authenticated-orcid":false,"given":"Paula M.C.","family":"Torres","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8912-5851","authenticated-orcid":false,"given":"Denise","family":"Jahn","sequence":"additional","affiliation":[]},{"given":"Nilza","family":"Ribeiro","sequence":"additional","affiliation":[]},{"given":"Tiago R.","family":"Correia","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3388-6042","authenticated-orcid":false,"given":"Miguel","family":"Coelho","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1981-6646","authenticated-orcid":false,"given":"T\u00e2nia S.S.","family":"Carvalho","sequence":"additional","affiliation":[]},{"given":"Agnes","family":"Ellinghaus","sequence":"additional","affiliation":[]},{"given":"Ana Prates","family":"Soares","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9565-7640","authenticated-orcid":false,"given":"Carsten","family":"Rendenbach","sequence":"additional","affiliation":[]},{"given":"Jo\u00e3o F.","family":"Mano","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5719-0867","authenticated-orcid":false,"given":"Katharina","family":"Schmidt-Bleek","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1269-8683","authenticated-orcid":false,"given":"Susana M.","family":"Olhero","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/j.actbio.2025.12.014_bib0001","doi-asserted-by":"crossref","unstructured":"Bone grafting - recent advances with special references to cranio-maxillofacial surgery, 2018. https:\/\/doi.org\/10.5772\/intechopen.73956.","DOI":"10.5772\/intechopen.73956"},{"key":"10.1016\/j.actbio.2025.12.014_bib0002","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s40001-021-00593-9","article-title":"Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature","volume":"26","author":"Migliorini","year":"2021","journal-title":"Eur. J. Med. Res."},{"key":"10.1016\/j.actbio.2025.12.014_bib0003","article-title":"Bone grafts and biomaterials substitutes for bone defect repair: A review","author":"Wang","year":"2017","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0004","first-page":"1379","article-title":"Improvement of the strength of calcium phosphate cements: systematic and meta-analysis","volume":"14","author":"Kiakojoori","year":"2020","journal-title":"Eurasian J. Biosci."},{"key":"10.1016\/j.actbio.2025.12.014_bib0005","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1021\/acsomega.0c03927","article-title":"Characterization and in vitro evaluations of injectable calcium phosphate cement doped with magnesium and strontium","volume":"6","author":"Arkin","year":"2021","journal-title":"ACS. Omega"},{"key":"10.1016\/j.actbio.2025.12.014_bib0006","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bsecv.2017.05.001","article-title":"Calcium phosphates for biomedical applications","volume":"56","author":"Canillas","year":"2017","journal-title":"Bol. Soc. Esp. Ceram. Vidr."},{"key":"10.1016\/j.actbio.2025.12.014_bib0007","series-title":"Biomaterials for bone tissue engineering scaffolds: A review","author":"Qu","year":"2019"},{"key":"10.1016\/j.actbio.2025.12.014_bib0008","doi-asserted-by":"crossref","first-page":"5939","DOI":"10.1016\/j.ceramint.2021.11.268","article-title":"A deep insight into the preparation of ceramic bone scaffolds utilizing robocasting technique","volume":"48","author":"Monfared","year":"2022","journal-title":"Ceram. Int."},{"key":"10.1016\/j.actbio.2025.12.014_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2022.e10651","article-title":"Robocasting of advanced ceramics: ink optimization and protocol to predict the printing parameters - A review","author":"Lamnini","year":"2022","journal-title":"Heliyon"},{"key":"10.1016\/j.actbio.2025.12.014_bib0010","doi-asserted-by":"crossref","DOI":"10.1039\/D2BM00035K","article-title":"Engineering biomaterials to 3D-print scaffolds for bone regeneration: practical and theoretical consideration","author":"Ansari","year":"2022","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.actbio.2025.12.014_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2018.09.050","article-title":"Novel sintering-free scaffolds obtained by additive manufacturing for concurrent bone regeneration and drug delivery: proof of concept","author":"Marques","year":"2019","journal-title":"Mater. Sci. Eng."},{"key":"10.1016\/j.actbio.2025.12.014_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2022.112690","article-title":"Toughening robocast chitosan\/biphasic calcium phosphate composite scaffolds with silk fibroin: tuning printable inks and scaffold structure for bone regeneration","author":"Torres","year":"2022","journal-title":"Biomater. Adv."},{"key":"10.1016\/j.actbio.2025.12.014_bib0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/biomedicines10123242","article-title":"Alternative geometries for 3D bioprinting of calcium phosphate cement as bone substitute","volume":"10","author":"Blankenburg","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.actbio.2025.12.014_bib0014","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/jcm10122654","article-title":"Adapting the pore size of individual, 3d-printed cpc scaffolds in maxillofacial surgery","volume":"10","author":"Muallah","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.actbio.2025.12.014_bib0015","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/acc903","article-title":"Support-less ceramic 3D printing of bioceramic structures using a hydrogel bath","volume":"15","author":"Raja","year":"2023","journal-title":"Biofabrication"},{"key":"10.1016\/j.actbio.2025.12.014_bib0016","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.actbio.2022.01.034","article-title":"Composites consisting of calcium phosphate cements and mesoporous bioactive glasses as a 3D plottable drug delivery system","volume":"156","author":"Richter","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0017","doi-asserted-by":"crossref","unstructured":"Y. Wu, L. Woodbine, A.M. Carr, A.R. Pillai, A. Nokhodchi, M. Maniruzzaman, 3D Printed calcium phosphate cement (CPC) sca ff olds for anti-cancer drug delivery, (2020).","DOI":"10.3390\/pharmaceutics12111077"},{"key":"10.1016\/j.actbio.2025.12.014_bib0018","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.actbio.2024.02.012","article-title":"Toughening 3D printed biomimetic hydroxyapatite scaffolds: polycaprolactone-based self-hardening inks","volume":"177","author":"del-Mazo-Barbara","year":"2024","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0019","doi-asserted-by":"crossref","DOI":"10.1002\/adem.202300789","article-title":"Aqueous calcium phosphate cement inks for 3D printing","volume":"25","author":"Weichhold","year":"2023","journal-title":"Adv. Eng. Mater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0020","doi-asserted-by":"crossref","DOI":"10.1002\/adem.202201559","article-title":"Preparation and properties of self-setting calcium phosphate scaffolds: effect of pore architecture","author":"Qian","year":"2023","journal-title":"Adv. Eng. Mater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0021","article-title":"About the mechanical strength of calcium phosphate cement scaffolds","author":"Bertrand","year":"2023","journal-title":"Des"},{"key":"10.1016\/j.actbio.2025.12.014_bib0022","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.actbio.2022.12.038","article-title":"3D extrusion printing of density gradients by variation of sinusoidal printing paths for tissue engineering and beyond","volume":"158","author":"Kilian","year":"2023","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.actbio.2008.03.004","article-title":"Mechanisms underlying the limited injectability of hydraulic calcium phosphate paste","author":"Habib","year":"2008","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.actbio.2012.11.028","article-title":"Relevance of the setting reaction to the injectability of tricalcium phosphate pastes","author":"Montufar","year":"2013","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0025","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.actbio.2015.04.006","article-title":"Injectability of calcium phosphate pastes: effects of particle size and state of aggregation of \u03b2-tricalcium phosphate powders","volume":"21","author":"Torres","year":"2015","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0026","article-title":"Photopolymerizable platelet lysate hydrogels for customizable 3D cell culture platforms","volume":"7","author":"Santos","year":"2018","journal-title":"Adv. Heal. Mater"},{"key":"10.1016\/j.actbio.2025.12.014_bib0027","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1515\/med-2016-0048","article-title":"Platelet Rich Plasma: A short overview of certain bioactive components","volume":"11","author":"Pavlovic","year":"2016","journal-title":"Open Med."},{"key":"10.1016\/j.actbio.2025.12.014_bib0028","first-page":"1","article-title":"A review on the enhancement of calcium phosphate cement with biological materials in bone defect healing","volume":"13","author":"Wong","year":"2021","journal-title":"Polym"},{"key":"10.1016\/j.actbio.2025.12.014_bib0029","article-title":"Human protein-based porous scaffolds as platforms for xeno-free 3D cell culture","volume":"11","author":"Santos","year":"2022","journal-title":"Adv. Heal. Mater"},{"key":"10.1016\/j.actbio.2025.12.014_bib0030","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.1002\/jbm.b.34036","article-title":"Effects of platelet-rich plasma on biological activity and bone regeneration of brushite-based calcium phosphate cement","volume":"106","author":"Hasan","year":"2018","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0031","first-page":"E737","article-title":"The incorporation of platelet-rich plasma into calcium phosphate cement enhances bone regeneration in osteoporosis","volume":"17","author":"Cho","year":"2014","journal-title":"Pain. Physician"},{"key":"10.1016\/j.actbio.2025.12.014_bib0032","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jdent.2011.11.003","article-title":"Calcium phosphate bone cement with 10 wt % platelet-rich plasma in vitro and in vivo","volume":"40","author":"Chen","year":"2012","journal-title":"J. Dent."},{"key":"10.1016\/j.actbio.2025.12.014_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.129086","article-title":"Lyophilized platelet rich fibrin and gelatin incorporated bioadhesive bone cement composite for repair of mandibular continuity defects","volume":"258","author":"Anthraper","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.actbio.2025.12.014_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2023.104690","article-title":"Calvaria defect regeneration via human periodontal ligament stem cells and prevascularized scaffolds in athymic rats","volume":"138","author":"Zhao","year":"2023","journal-title":"J. Dent."},{"key":"10.1016\/j.actbio.2025.12.014_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmats.2022.977853","article-title":"Novel injectable calcium phosphate scaffold with human periodontal ligament stem cell encapsulation in microbeads for bone regeneration","volume":"9","author":"Qiu","year":"2022","journal-title":"Front. Mater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0036","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1021\/acsbiomaterials.7b00640","article-title":"Calcium-deficient hydroxyapatite \/collagen \/ platelet-rich plasma scaffold with controlled release function for hard tissue regeneration","author":"Lee","year":"2018","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.actbio.2025.12.014_bib0037","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.jeurceramsoc.2015.09.037","article-title":"Influence of Mg-doping, calcium pyrophosphate impurities and cooling rate on the allotropic \u03b1\u2194\u03b2-tricalcium phosphate phase transformations","volume":"36","author":"Torres","year":"2016","journal-title":"J. Eur. Ceram. Soc."},{"key":"10.1016\/j.actbio.2025.12.014_bib0038","series-title":"The Rheology Handbook: For users of rotational and oscillatory rheometers","author":"Mezger","year":"2020"},{"key":"10.1016\/j.actbio.2025.12.014_bib0039","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.mattod.2015.10.008","article-title":"Calcium phosphates in biomedical applications: materials for the future?","volume":"19","author":"Habraken","year":"2016","journal-title":"Mater. Today"},{"key":"10.1016\/j.actbio.2025.12.014_bib0040","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.msec.2018.12.071","article-title":"Synthesis of calcium-deficient hydroxyapatite nanowires and nanotubes performed by template-assisted electrodeposition","volume":"98","author":"Beaufils","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.actbio.2025.12.014_bib0041","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.actbio.2022.08.040","article-title":"\u03b1-TCP-based calcium phosphate cements: A critical review","volume":"151","author":"Tronco","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0042","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actbio.2016.11.019","article-title":"Critical review: injectability of calcium phosphate pastes and cements","volume":"50","author":"O\u2019Neill","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.actbio.2025.12.014_bib0043","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1177\/00220345970760041201","article-title":"Setting reaction and hardening of an apatitic calcium phosphate cement","volume":"76","author":"Ginebra","year":"1997","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.actbio.2025.12.014_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.jeurceramsoc.2021.08.031","article-title":"Rheological characterisation of ceramic inks for 3D direct ink writing: A review","author":"del-Mazo-Barbara","year":"2021","journal-title":"J. Eur. Ceram. Soc."},{"key":"10.1016\/j.actbio.2025.12.014_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfa.2023.131426","article-title":"Direct ink writing of ATZ composites based on inks prepared by colloidal or hydrogel route: linking inks rheology with mechanical properties","volume":"668","author":"L\u00e9varo","year":"2023","journal-title":"Colloids Surf. Physicochem. Eng. Asp."},{"key":"10.1016\/j.actbio.2025.12.014_bib0046","doi-asserted-by":"crossref","DOI":"10.1016\/j.mser.2024.100841","article-title":"Ceramics and ceramic composites for biomedical engineering applications via Direct Ink Writing: overall scenario, advances in the improvement of mechanical and biological properties and innovations","volume":"161","author":"dos Santos","year":"2024","journal-title":"Mater. Sci. Eng.: R: Rep."},{"key":"10.1016\/j.actbio.2025.12.014_bib0047","doi-asserted-by":"crossref","first-page":"8249","DOI":"10.1016\/j.ceramint.2018.02.005","article-title":"Influence of the Ca\/P ratio and cooling rate on the allotropic \u03b1\u2194\u03b2-tricalcium phosphate phase transformations","volume":"44","author":"Brazete","year":"2018","journal-title":"Ceram. Int."},{"key":"10.1016\/j.actbio.2025.12.014_bib0048","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1016\/j.jeurceramsoc.2022.12.008","article-title":"Optimization of mechanical properties of robocast alumina parts through control of the paste rheology","volume":"43","author":"Maillard","year":"2023","journal-title":"J. Eur. Ceram. Soc."},{"key":"10.1016\/j.actbio.2025.12.014_bib0049","doi-asserted-by":"crossref","DOI":"10.1002\/mame.202500154","article-title":"Development of bioactive 3D printed MC\/Al\/gel\/HA scaffolds with enhanced printability, flexibility and mechanical strength","volume":"310","author":"Karaca","year":"2025","journal-title":"Macromol. Mater. Eng."},{"key":"10.1016\/j.actbio.2025.12.014_bib0050","article-title":"3D printing of multi-scale porous \u03b2-tricalcium phosphate scaffolds: mechanical properties and degradation","volume":"19","author":"Chan","year":"2024","journal-title":"Open Ceram."},{"key":"10.1016\/j.actbio.2025.12.014_bib0051","doi-asserted-by":"crossref","DOI":"10.1186\/s41038-018-0121-4","article-title":"Review of additive manufactured tissue engineering scaffolds: relationship between geometry and performance","volume":"6","author":"Gleadall","year":"2018","journal-title":"Burns. Trauma"},{"key":"10.1016\/j.actbio.2025.12.014_bib0052","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s12929-023-00972-w","article-title":"Expanding applications of allogeneic platelets, platelet lysates, and platelet extracellular vesicles in cell therapy, regenerative medicine, and targeted drug delivery","volume":"30","author":"Burnouf","year":"2023","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.actbio.2025.12.014_bib0053","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1111\/j.1537-2995.2007.01220.x","article-title":"Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells","volume":"47","author":"Schallmoser","year":"2007","journal-title":"Transfus"},{"key":"10.1016\/j.actbio.2025.12.014_bib0054","doi-asserted-by":"crossref","DOI":"10.1039\/D3BM01933K","article-title":"Photocrosslinkable microgels derived from human platelet lysates: injectable biomaterials for cardiac cell culture","author":"Santos","year":"2024","journal-title":"Biomater. Sci."},{"key":"10.1016\/j.actbio.2025.12.014_bib0055","doi-asserted-by":"crossref","first-page":"9318","DOI":"10.1016\/j.biomaterials.2013.08.018","article-title":"The effect of platelet lysate on osteoblast proliferation associated with a transient increase of the inflammatory response in bone regeneration","volume":"34","author":"Ruggiu","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.actbio.2025.12.014_bib0056","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4252\/wjsc.v8.i2.47","article-title":"Use of platelet lysate for bone regeneration-are we ready for clinical translation?","volume":"8","author":"Altaie","year":"2016","journal-title":"World J. Stem Cells"},{"key":"10.1016\/j.actbio.2025.12.014_bib0057","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bone.2016.06.013","article-title":"The roles of vascular endothelial growth factor in bone repair and regeneration","volume":"91","author":"Hu","year":"2016","journal-title":"Bone"}],"container-title":["Acta Biomaterialia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706125009080?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1742706125009080?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T15:27:52Z","timestamp":1773934072000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1742706125009080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":57,"alternative-id":["S1742706125009080"],"URL":"https:\/\/doi.org\/10.1016\/j.actbio.2025.12.014","relation":{},"ISSN":["1742-7061"],"issn-type":[{"value":"1742-7061","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhancing bioactivity of calcium-phosphate cement-based 3D printed scaffolds with human platelet lysates: in vitro and in vivo validation","name":"articletitle","label":"Article Title"},{"value":"Acta Biomaterialia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.actbio.2025.12.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of Acta Materialia Inc.","name":"copyright","label":"Copyright"}]}}