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Cell Sci."},{"key":"10.1016\/j.cell.2026.07.022_bib84","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1182\/blood-2005-01-0425","article-title":"Dendritic cells regulate T-cell deattachment through the integrin-interacting protein CYTIP","volume":"107","author":"Hofer","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.cell.2026.07.022_bib85","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-018-04686-8","article-title":"Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells","volume":"9","author":"Oberkampf","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cell.2026.07.022_bib86","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/s41421-020-00198-2","article-title":"Atomic structure of human TOM core complex","volume":"6","author":"Wang","year":"2020","journal-title":"Cell Discov."},{"key":"10.1016\/j.cell.2026.07.022_bib87","unstructured":"World Health Organization. (2023). 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