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Persistent infection of the gastric mucosa with <jats:italic>H. pylori<\/jats:italic> and concurrent chronic gastritis are risk factors for ulcer disease and gastric carcinoma. Therefore, interactions at the <jats:italic>H. pylori<\/jats:italic>\u2013epithelial interface are important to understand the pathogenesis of these bacteria and the host responses that contribute to disease development. 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