{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T09:02:38Z","timestamp":1771664558159,"version":"3.50.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["New Biotechnology"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.nbt.2020.01.007","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T02:43:39Z","timestamp":1580265819000},"page":"4-10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":58,"special_numbering":"C","title":["Valorization of raw brewers\u2019 spent grain through the production of volatile fatty acids"],"prefix":"10.1016","volume":"57","author":[{"given":"Margarida","family":"Ribau Teixeira","sequence":"first","affiliation":[]},{"given":"Eliana C.","family":"Guarda","sequence":"additional","affiliation":[]},{"given":"Elisabete B.","family":"Freitas","sequence":"additional","affiliation":[]},{"given":"Claudia F.","family":"Galinha","sequence":"additional","affiliation":[]},{"given":"Anouk F.","family":"Duque","sequence":"additional","affiliation":[]},{"given":"Maria A.M.","family":"Reis","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/j.nbt.2020.01.007_bib0005","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1002\/jsfa.6486","article-title":"Brewer\u2019s spent grain: a valuable feedstock for industrial applications","volume":"94","author":"Mussatto","year":"2014","journal-title":"J Sci Food Agric"},{"key":"10.1016\/j.nbt.2020.01.007_bib0010","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s12649-012-9108-8","article-title":"Biotechnological potential of brewers spent grain and its recent applications","volume":"2","author":"Xiros","year":"2012","journal-title":"Waste Biomass Valorization"},{"key":"10.1016\/j.nbt.2020.01.007_bib0015","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00217-015-2461-7","article-title":"Brewer\u2019s spent grain: source of value\u2011added polysaccharides for the food industry in reference to the health claims","volume":"241","author":"Steiner","year":"2015","journal-title":"Eur Food Res Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0020","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.enconman.2017.12.088","article-title":"Overall evaluation of microwave-assisted alkali pretreatment for enhancement of biomethane production from brewers\u2019 spent grain","volume":"158","author":"Kan","year":"2018","journal-title":"Energy Convers Manage"},{"key":"10.1016\/j.nbt.2020.01.007_bib0025","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jclepro.2017.07.197","article-title":"Biogas production from brewery spent grain as a mono-substrate in a two-stage process composed of solid-state anaerobic digestion and granular biomass reactors","volume":"166","author":"Panjicko","year":"2017","journal-title":"J Clean Prod"},{"key":"10.1016\/j.nbt.2020.01.007_bib0030","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.biortech.2015.04.073","article-title":"Biomethanation from enzymatically hydrolyzed brewer\u2019s spent grain: impact of rapid increase in loadings","volume":"190","author":"Wang","year":"2015","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0035","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.biortech.2015.03.029","article-title":"Biogas production from brewery spent grain enhanced by bioaugmentation with hydrolytic anaerobic bacteria","volume":"186","author":"\u010cater","year":"2015","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0040","doi-asserted-by":"crossref","first-page":"6112","DOI":"10.1016\/j.biortech.2011.02.059","article-title":"Manufacture and prebiotic potential of oligosaccharides derived from industrial solid wastes","volume":"101","author":"Gull\u00f3n","year":"2011","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0045","doi-asserted-by":"crossref","first-page":"13859","DOI":"10.1016\/j.ijhydene.2012.04.090","article-title":"Hydrogen generation in microbial electrolysis cell feeding with fermentation liquid of waste activated sludge","volume":"37","author":"Liu","year":"2012","journal-title":"Int J Hydrogen Energy"},{"key":"10.1016\/j.nbt.2020.01.007_bib0050","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.rser.2013.11.024","article-title":"Energy and hydraulic efficiency inconventional water supply systems","volume":"30","author":"Vilanova","year":"2014","journal-title":"Renewable Sustainable Energy Rev"},{"key":"10.1016\/j.nbt.2020.01.007_bib0055","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1021\/es1031882","article-title":"Pilot-scale waste activated sludge alkaline fermentation, fermentation liquid separation, and application of fermentation liquid to improve biological nutrient removal","volume":"45","author":"Li","year":"2011","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbt.2013.10.010","article-title":"Response of a three-stage process for PHA production by mixed microbial cultures to feedstock shift: impact on polymer composition","volume":"31","author":"Duque","year":"2014","journal-title":"N Biotechnol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0065","series-title":"Mixed culture processes for polyhydroxyalkanoate production from agro-industrial Surplus\/Wastes as feedstocks. Wastes from agriculture, forestry and food processing","first-page":"669","author":"Reis","year":"2011"},{"key":"10.1016\/j.nbt.2020.01.007_bib0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.cej.2013.09.002","article-title":"A review of the production and applications of waste-derived volatile fatty acids","volume":"235","author":"Lee","year":"2014","journal-title":"Chem Eng J"},{"key":"10.1016\/j.nbt.2020.01.007_bib0075","doi-asserted-by":"crossref","first-page":"818","DOI":"10.17344\/acsi.2015.1534","article-title":"Anaerobic biodegradation of raw and pre-treated brewery spent grain utilizing solid state anaerobic digestion","volume":"62","author":"Panjicko","year":"2015","journal-title":"Acta Chim Slov"},{"key":"10.1016\/j.nbt.2020.01.007_bib0080","first-page":"158","article-title":"Marin\u0161ek-Logar R. Anaerobic digestion of brewery spent grain in a semi-continuous bioreactor: inhibition by phenolic degradation products","volume":"58","author":"Se\u017eun","year":"2011","journal-title":"Acta Chim Slov"},{"key":"10.1016\/j.nbt.2020.01.007_bib0085","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.biortech.2014.09.103","article-title":"Anaerobic digestion of lignocellulosic biomass: challenges and opportunities","volume":"178","author":"Sawatdeenarunat","year":"2015","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0090","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.wasman.2017.06.010","article-title":"Anaerobic digestion of tuna waste for the production of volatile fatty acids","volume":"68","author":"Berm\u00fadez-Penabad","year":"2017","journal-title":"Waste Manag"},{"key":"10.1016\/j.nbt.2020.01.007_bib0095","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.biortech.2013.06.025","article-title":"Volatile fatty acids production from food waste: effects of pH, temperature, and organic loading rate","volume":"143","author":"Jiang","year":"2013","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0100","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.wasman.2019.05.010","article-title":"Optimization of urban waste fermentation for volatile fatty acids production","volume":"92","author":"Moretto","year":"2019","journal-title":"Waste Manag"},{"key":"10.1016\/j.nbt.2020.01.007_bib0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbt.2016.07.001","article-title":"Dynamic change of pH in acidogenic fermentation of cheese whey towards polyhydroxyalkanoates production: impact on performance and microbial population","volume":"37","author":"Gouveia","year":"2017","journal-title":"N Biotechnol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0110","series-title":"Standard methods for the examination of water and wastewater","author":"APHA","year":"2005"},{"key":"10.1016\/j.nbt.2020.01.007_bib0115","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/j.wasman.2012.03.020","article-title":"Evaluation of the biomethane potential of solid fish waste","volume":"32","author":"Eiroa","year":"2012","journal-title":"Waste Manag"},{"key":"10.1016\/j.nbt.2020.01.007_bib0120","series-title":"Molecular microbial ecology manual","first-page":"1","article-title":"In situ identification of microorganisms by whole cell hybridization with rRNA-targeted nucleic acid probes","author":"Amann","year":"1995"},{"key":"10.1016\/j.nbt.2020.01.007_bib0125","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1128\/aem.56.6.1919-1925.1990","article-title":"Combination of 16S rRNA-targeted oligonucleotide probes with flow cytometry for analyzing mixed microbial populations","volume":"56","author":"Amann","year":"1990","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0130","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0723-2020(99)80053-8","article-title":"The domainspecific probe EUB338 is insufficient for the detection of all Bacteria: development and evaluation of a more comprehensive probe set","volume":"22","author":"Daims","year":"1999","journal-title":"Syst Appl Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0135","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.mimet.2005.07.007","article-title":"An update and optimisation of oligonucleotide probes targeting methanogenic Archaea for use in fluorescence in situ hybridisation (FISH)","volume":"65","author":"Crocetti","year":"2006","journal-title":"J Microbiol Methods"},{"key":"10.1016\/j.nbt.2020.01.007_bib0140","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1099\/mic.0.28065-0","article-title":"Anaerobic and aerobic metabolism of glycogen-accumulating organisms selected with propionate as the sole carbon source","volume":"152","author":"Oehmen","year":"2006","journal-title":"Microbiology"},{"key":"10.1016\/j.nbt.2020.01.007_bib0145","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0723-2020(11)80121-9","article-title":"Phylogenetic oligodeoxynucleotide probes for the major subclasses of Proteobacteria: problems and solutions","volume":"15","author":"Manz","year":"1992","journal-title":"Syst Appl Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0150","doi-asserted-by":"crossref","first-page":"5064","DOI":"10.1128\/AEM.68.10.5064-5081.2002","article-title":"Oligonucleotide microarray for 16S rRNA gene-based detection of all recognized lineages of sulfate-reducing prokaryotes in the environment","volume":"68","author":"Loy","year":"2002","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0155","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1099\/13500872-142-5-1097","article-title":"Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum cytophaga-flavobacter-bacteroides in the natural environment","volume":"142","author":"Manz","year":"1996","journal-title":"Microbiology"},{"key":"10.1016\/j.nbt.2020.01.007_bib0160","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1128\/AEM.72.3.2022-2030.2006","article-title":"Macroscopic streamer growths in acidic, metal-rich mine waters in north wales consist of novel and remarkably simple bacterial communities","volume":"72","author":"Hallberg","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0165","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1099\/00221287-140-10-2849","article-title":"In situ probing of Gram-positive bacteria with high DNA G + C content using 23S rRNA-targeted oligonucleotides","volume":"10","author":"Roller","year":"1994","journal-title":"Microbiology"},{"key":"10.1016\/j.nbt.2020.01.007_bib0170","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1128\/AEM.67.1.411-419.2001","article-title":"Investigation of Candidate Division TM7, a recently recognized major lineage of the domain Bacteria with no known pure-culture representatives","volume":"67","author":"Hugenholtz","year":"2001","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0175","doi-asserted-by":"crossref","first-page":"D586","DOI":"10.1093\/nar\/gkv1232","article-title":"Rattei T. probeBase \u2014an online resource for rRNAtargeted oligonucleotide probes and primers: new features","volume":"44","author":"Greuter","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.nbt.2020.01.007_bib0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0169-7439(00)00071-X","article-title":"The N-way toolbox for MATLAB","volume":"52","author":"Andersson CA","year":"2000","journal-title":"Chemometr Intell Lab Syst"},{"key":"10.1016\/j.nbt.2020.01.007_bib0185","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.biortech.2015.09.095","article-title":"Anaerobic digestion of microalgal biomass: challenges, opportunities and research needs","volume":"198","author":"Gonzalez-Fernandez","year":"2015","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0190","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.biortech.2018.07.042","article-title":"Bio-based volatile fatty acid production and recovery from waste streams: current status and future challenges","volume":"268","author":"Atasoy","year":"2018","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0195","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1061\/(ASCE)0733-9372(2000)126:12(1145)","article-title":"Effect of HRT on mesophilic acidogenesis of dairy wastewater","volume":"126","author":"Fang","year":"2000","journal-title":"J Environ Eng (New York)"},{"key":"10.1016\/j.nbt.2020.01.007_bib0200","doi-asserted-by":"crossref","first-page":"7866","DOI":"10.1016\/j.biortech.2007.06.028","article-title":"Anaerobic organic acid production of food waste in once-a-day feeding and drawing-off bioreactor","volume":"99","author":"Lim","year":"2008","journal-title":"Bioresour Technol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0205","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1016\/j.procbio.2015.04.007","article-title":"Synthetic soft drink wastewater suitability for the production of volatile fatty acids","volume":"50","author":"Vergine","year":"2015","journal-title":"Process Biochem"},{"key":"10.1016\/j.nbt.2020.01.007_bib0210","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1007\/s11274-014-1664-6","article-title":"Illumina sequencing-based analyses of bacterial communities during short-chain fatty-acid production from food waste and sewage sludge fermentation at different pH values","volume":"30","author":"Cheng","year":"2014","journal-title":"World J Microbiol Biotechnol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0215","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s00203-004-0722-0","article-title":"Alkaliflexus imshenetskii gen. Nov. Sp. nov., a new alkaliphilic gliding carbohydrate-fermenting bacterium with propionate formation from a soda lake","volume":"182","author":"Zhilina","year":"2004","journal-title":"Arch Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0220","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/BF00244257","article-title":"Cytophaga xylanolytica sp. nov., a xylan-degrading, anaerobic gliding bacterium","volume":"159","author":"Haack","year":"1993","journal-title":"Arch Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0225","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1099\/00207713-52-1-173","article-title":"Anaerophaga thermohalophila gen. nov., sp. nov., a moderately thermohalophilic, strictly anaerobic fermentative bacterium","volume":"52","author":"Denger","year":"2002","journal-title":"Int J Syst Evol Microbiol"},{"key":"10.1016\/j.nbt.2020.01.007_bib0230","series-title":"Biological Treatment of Solid Waste Enhancing Sustainability","first-page":"23","article-title":"Effect of increasing total solids contents on anaerobic digestion of food waste under mesophilic conditions: performance and microbial characteristics analysis","author":"Yi","year":"2015"},{"key":"10.1016\/j.nbt.2020.01.007_bib0235","doi-asserted-by":"crossref","first-page":"6661","DOI":"10.1128\/JB.186.19.6661-6666.2004","article-title":"Major role of NAD-dependent lactate dehydrogenases in aerobic lactate utilization in Lactobacillus plantarum during early stationary phase","volume":"186","author":"Goffin","year":"2004","journal-title":"J Bacteriol"}],"container-title":["New Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871678419304042?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871678419304042?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T10:03:30Z","timestamp":1761732210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1871678419304042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":47,"alternative-id":["S1871678419304042"],"URL":"https:\/\/doi.org\/10.1016\/j.nbt.2020.01.007","relation":{},"ISSN":["1871-6784"],"issn-type":[{"value":"1871-6784","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Valorization of raw brewers\u2019 spent grain through the production of volatile fatty acids","name":"articletitle","label":"Article Title"},{"value":"New Biotechnology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nbt.2020.01.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}