{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:35:59Z","timestamp":1773858959102,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1998,7,1]],"date-time":"1998-07-01T00:00:00Z","timestamp":899251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinica Chimica Acta"],"published-print":{"date-parts":[[1998,7]]},"DOI":"10.1016\/s0009-8981(98)00082-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T12:06:05Z","timestamp":1027598765000},"page":"185-196","source":"Crossref","is-referenced-by-count":17,"title":["Erythrocyte membrane band 3 profile imposed by cellular aging, by activated neutrophils and by neutrophilic elastase"],"prefix":"10.1016","volume":"275","author":[{"given":"Alice","family":"Santos-Silva","sequence":"first","affiliation":[]},{"given":"Elisabeth M.B","family":"Castro","sequence":"additional","affiliation":[]},{"given":"Nat\u00e9rcia A","family":"Teixeira","sequence":"additional","affiliation":[]},{"given":"Francisco Carvalho","family":"Guerra","sequence":"additional","affiliation":[]},{"given":"Alexandre","family":"Quintanilha","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0009-8981(98)00082-5_BIB1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0021-9150(95)05543-6","article-title":"Altered erythrocyte membrane band 3 profile as a marker in patients at risk for cardiovascular disease","volume":"116","author":"Santos-Silva","year":"1995","journal-title":"Atherosclerosis"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1097\/00041433-199308000-00004","article-title":"Blood viscosity and cardiovascular risk","volume":"4","author":"Lowe","year":"1993","journal-title":"Curr Opin Lipidol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB3","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1177\/030098588802500608","article-title":"Neutrophil-induced erythrocyte injury: a potential cause of erythrocyte destruction in the anaemia associated with inflammatory disease","volume":"25","author":"Weiss","year":"1988","journal-title":"Vet Pathol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB4","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/BF00599241","article-title":"Do invading leukocytes contribute to the decreases in glutathione concentrations indicating oxidative stress in exercised muscle, or are they important for its recovery?","volume":"68","author":"Duarte","year":"1994","journal-title":"Eur J Appl Physiol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB5","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0301-2115(95)02203-J","article-title":"Lactoferrin as a sensitive blood marker of neutrophil activation in normal pregnancies","volume":"62","author":"Rebelo","year":"1995","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB6","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1016\/S0021-9258(19)81056-6","article-title":"Neutrophil-mediated methemoglobin formation in the erythrocyte. The role of superoxide and hydrogen peroxide","volume":"257","author":"Weiss","year":"1982","journal-title":"J Biol Chem"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB7","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1182\/blood.V64.5.1079.1079","article-title":"Neutrophils mediate lipid peroxidation in human red cells","volume":"64","author":"Claster","year":"1984","journal-title":"Blood"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB8","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1172\/JCI112095","article-title":"Oxygen radical-induced erythrocyte hemolysis by neutrophils. Critical role of iron and lactoferrin","volume":"76","author":"Vercellotti","year":"1985","journal-title":"J Clin Invest"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB9","first-page":"92a","article-title":"Human neutrophil elastase mediate red cell membrane damage","volume":"68","author":"Claster","year":"1986","journal-title":"Blood"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB10","first-page":"201","article-title":"Neutrophil-induced K+ leak in human red cells: a potential mechanism for infection-mediated hemolysis","volume":"109","author":"Claster","year":"1987","journal-title":"J Lab Clin Med"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB11","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3233\/BIR-1992-292-303","article-title":"Effects of superoxide anions on red cell deformability and membrane proteins","volume":"29","author":"Uyesaka","year":"1992","journal-title":"Biorheology"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB12","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/jlb.51.1.19","article-title":"Neutrophil-mediated immunoglobulin binding to erythrocytes involves proteolytic and oxidative injury","volume":"51","author":"Weiss","year":"1992","journal-title":"J Leukocyte Biol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB13","first-page":"49","article-title":"Activated granulocyte induced alterations in red blood cells and protection by antioxidant enzymes","volume":"16","author":"Baskurt","year":"1996","journal-title":"Clin Hemorheol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB14","doi-asserted-by":"crossref","unstructured":"Lutz HU. Erythrocyte clearance blood cell biochemistry. In: Harris JR, editor. Erythroid cells. New York: Plenum, 1990:81\u2013120.","DOI":"10.1007\/978-1-4757-9528-8_4"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB15","doi-asserted-by":"crossref","unstructured":"Brovelli A, Castellana MA, Minetti G, Piccinini G, Seppi C, Renzis MR, Balduini C. Conformational changes and oxidation of membrane proteins in senescent human erythrocytes. In: Magnani M, De Flora A, editors. Red blood cell aging. New York: Plenum, 1991:59\u201373.","DOI":"10.1007\/978-1-4684-5985-2_6"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB16","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1600-0609.1994.tb01282.x","article-title":"Determinants of red blood cell deformability in relation to cell age","volume":"52","author":"Bosch","year":"1994","journal-title":"Eur J Haematol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB17","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/jss.400090409","article-title":"Role of physiologic autoantibody in the removal of senescent human red cells","volume":"9","author":"Kay","year":"1978","journal-title":"J Supramol Struct"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB18","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1073\/pnas.80.6.1631","article-title":"Senescent cell antigen is immunologically related to band 3","volume":"80","author":"Kay","year":"1983","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB19","doi-asserted-by":"crossref","first-page":"5753","DOI":"10.1073\/pnas.81.18.5753","article-title":"Localization of senescent cell antigen on band 3","volume":"81","author":"Kay","year":"1984","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB20","doi-asserted-by":"crossref","first-page":"7368","DOI":"10.1073\/pnas.84.21.7368","article-title":"Naturally occurring anti-band 3 antibodies and complement together mediate phagocytosis of oxidatively stressed human erythrocytes","volume":"84","author":"Lutz","year":"1987","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB21","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0887-7963(92)70170-9","article-title":"Naturally occurring anti-band 3 antibodies","volume":"6","author":"Lutz","year":"1992","journal-title":"Transfus Med Rev"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB22","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0887-7963(91)70207-1","article-title":"Human erythrocyte aging: cellular and molecular biology","volume":"3","author":"Kay","year":"1991","journal-title":"Transfus Med Rev"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB23","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.1432-1033.1988.tb14147.x","article-title":"Degradation of the human erythrocyte membrane band 3 studied with monoclonal antibody directed against an epitope on the cytoplasmic fragment of band 3","volume":"174","author":"Czerwinki","year":"1988","journal-title":"Eur J Biochem"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB24","doi-asserted-by":"crossref","unstructured":"Low PS. Role of hemoglobin denaturation and band 3 clustering in initiating red cell removal. In: Magnani M, De Flora A, editors. Red blood cell aging. New York: Plenum, 1991:173\u2013183.","DOI":"10.1007\/978-1-4684-5985-2_16"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB25","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0022-1759(74)90109-4","article-title":"Single-step separation of red blood cells. Granulocytes and mononuclear leucocytes on discontinuous density gradient of Ficoll-hypaque","volume":"5","author":"English","year":"1974","journal-title":"J Immunol Methods"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB26","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0009-8981(79)90172-4","article-title":"Human erythrocyte fractionation in Percoll density gradients","volume":"98","author":"Rennie","year":"1979","journal-title":"Clin Chim Acta"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB27","first-page":"84","article-title":"Defici\u00eancia em glucose-6-fosfato desidrogenase (G6PD). Estabelecimento de valores de refer\u00eancia da sua actividade no eritr\u00f3cito. Estudo de dois hemizigotos","volume":"39","author":"Santos-Silva","year":"1989","journal-title":"Rev Port Farm"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB28","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0003-9861(63)90042-0","article-title":"The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes","volume":"100","author":"Dodge","year":"1963","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB29","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB30","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB31","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications","volume":"76","author":"Towbin","year":"1979","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB32","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1042\/bst0200774","article-title":"Interaction of the red cell membrane skeleton with the membrane","volume":"20","author":"Pinder","year":"1992","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB33","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0950-3536(05)80149-0","article-title":"The major integral proteins of the human red cell","volume":"6","author":"Tanner","year":"1993","journal-title":"Bailli\u00e8res Clin Hematol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB34","first-page":"1","article-title":"Structures, m\u00e9tabolisme et physiologie des globules rouges humains","volume":"13-000-R-10","author":"Boivin","year":"1994","journal-title":"H\u00e9matologie Ed T\u00e9ch Encyclop M\u00e9d Chir Paris"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB35","first-page":"5","article-title":"Fisiopatologia da membrana eritrocit\u00e1ria","volume":"47","author":"Santos-Silva","year":"1997","journal-title":"Rev Port Farm"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB36","doi-asserted-by":"crossref","first-page":"6133","DOI":"10.1021\/bi00368a045","article-title":"Restriction of the lateral motion of band 3 in the erythrocyte membrane by the cytoskeletal network: dependence on spectrin association state","volume":"25","author":"Tsuji","year":"1986","journal-title":"Biochemistry"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB37","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1126\/science.2020854","article-title":"Uncoupling of the spectrin-based skeleton from lipid bilayer in sickled red cells","volume":"252","author":"Liu","year":"1991","journal-title":"Science"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB38","first-page":"59","article-title":"Hereditary hemolytic anemias due to defects in membrane proteins","volume":"12","author":"Delaunay","year":"1993","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj2190001","article-title":"Oxygen toxicity, oxygen radicals, transition metals and disease","volume":"219","author":"Halliwell","year":"1984","journal-title":"Biochem J"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB40","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0021-9150(94)90121-X","article-title":"The effect of short-term myocardial ischemia on the expression of adhesion molecules and the oxidative burst of coronary sinus blood neutrophils","volume":"106","author":"Baj","year":"1994","journal-title":"Atherosclerosis"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB41","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0021-9150(94)05558-Z","article-title":"Evaluation of oxidative stress in patients with hyperlipidemia","volume":"117","author":"Ara\u00fajo","year":"1995","journal-title":"Atherosclerosis"},{"key":"10.1016\/S0009-8981(98)00082-5_BIB42","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0006-355X(96)00004-2","article-title":"Neutrophil activation in smokers","volume":"33","author":"Pitzer","year":"1996","journal-title":"Biorheology"}],"container-title":["Clinica Chimica Acta"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898198000825?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0009898198000825?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T12:05:48Z","timestamp":1620216348000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0009898198000825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,7]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1998,7]]}},"alternative-id":["S0009898198000825"],"URL":"https:\/\/doi.org\/10.1016\/s0009-8981(98)00082-5","relation":{},"ISSN":["0009-8981"],"issn-type":[{"value":"0009-8981","type":"print"}],"subject":[],"published":{"date-parts":[[1998,7]]}}}