{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T11:47:07Z","timestamp":1761392827014},"reference-count":21,"publisher":"Elsevier BV","issue":"8-9","license":[{"start":{"date-parts":[[1999,6,1]],"date-time":"1999-06-01T00:00:00Z","timestamp":928195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enzyme and Microbial Technology"],"published-print":{"date-parts":[[1999,6]]},"DOI":"10.1016\/s0141-0229(98)00141-0","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T19:10:36Z","timestamp":1027624236000},"page":"507-513","source":"Crossref","is-referenced-by-count":15,"title":["Continuous production and simultaneous precipitation of a dipeptide in a reversed micellar membrane reactor"],"prefix":"10.1016","volume":"24","author":[{"given":"M.L.M","family":"Serralheiro","sequence":"first","affiliation":[]},{"given":"D.M.F","family":"Prazeres and","sequence":"additional","affiliation":[]},{"given":"J.M.S","family":"Cabral","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0141-0229(98)00141-0_BIB1","unstructured":"Oyama, K. and Kihara, K. A new horizon for enzyme technology. Chemtech 1984, 2, 100\u2013105"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB2","doi-asserted-by":"crossref","unstructured":"Luthi, P. and Luisi, P. L. Enzymatic synthesis of hydrocarbon soluble peptides with reverse micelles. J. Am. Chem. Soc. 1984, 106, 7285\u20137286","DOI":"10.1021\/ja00335a092"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB3","doi-asserted-by":"crossref","unstructured":"Shield, J. W., Ferguson, H. D., Gleason, K. K., and Hatton, T. A. Enzymatic reactions in reversed micelles at low solubilized water concentrations. In: Biocatalysis and Biomimetics (Burrington, J. D. and Clark, D. S., Eds.). ACS Symposium Series 392, ACS, Washington DC, 1989, 90\u2013103","DOI":"10.1021\/bk-1989-0392.ch007"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB4","doi-asserted-by":"crossref","unstructured":"Jorba, X., Clap\u00e9s, P., Xaus, N., Calvet, S., Torres, J. L., Valencia, G., and Mata, J. Optimization and kinetic studies of the enzymatic synthesis of AcPheLeuNH2 in reversed micelles. Enzyme Microb. Technol. 1992, 14, 117\u2013124","DOI":"10.1016\/0141-0229(92)90168-N"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB5","doi-asserted-by":"crossref","unstructured":"Chang, P. S., Rhee, J. S., and Kim, J. J. Continuous glycerolysis of olive oil by Chromobacterium viscosum lipase immobilized on liposome in reversed micelles. Biotechnol. Bioeng. 1991, 38, 1159\u20131165","DOI":"10.1002\/bit.260381007"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB6","doi-asserted-by":"crossref","unstructured":"Chiang, C.-L. and Tsai, S.-W. Application of a recycle dialysis system in a reversed micellar reactor. J. Chem. Technol. Biotechnol. 1992, 54, 27\u201332","DOI":"10.1002\/jctb.280540106"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB7","doi-asserted-by":"crossref","unstructured":"Prazeres, D. M. F., Garcia, F. A. P., and Cabral, J. M. S. An ultrafiltration membrane bioreactor for the lipolysis of olive oil in reversed micellar media. Biotechnol. Bioeng. 1993, 41, 761\u2013770","DOI":"10.1002\/bit.260410802"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB8","doi-asserted-by":"crossref","unstructured":"Prazeres, D. M. F., Garcia, F. A. P., and Cabral, J. M. S. Continuous lipolysis in a reversed micellar membrane bioreactor. Bioprocess Eng. 1994, 10, 21\u201327","DOI":"10.1007\/BF00373531"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB9","doi-asserted-by":"crossref","unstructured":"Serralheiro, M. L. M., Prazeres, D. M. F., and Cabral, J. M. S. Dipeptide synthesis and separation in a reversed micellar membrane reactor. Enzyme Microb. Technol. 1994, 16, 1064\u20131073","DOI":"10.1016\/0141-0229(94)90144-9"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB10","doi-asserted-by":"crossref","unstructured":"Prazeres, D. M. F. and Cabral, J. M. S. Enzymatic membrane reactors and their applications. Enzyme Microb. Technol. 1994, 16, 1\u201313","DOI":"10.1016\/0141-0229(94)90030-2"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB11","unstructured":"Kullmann, W. Enzymatic Peptide Synthesis. CRC Press, Inc. Boca Raton, FL 1987"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB12","doi-asserted-by":"crossref","unstructured":"Serralheiro, M. L. M., and Cabral, J. M. S. Application of fractional factorial design to the study of enzymatic dipeptide synthesis in reverse micelles. In: Biocatalysis in Non-Conventional Media (Tramper, J., Vermue, M. H., Beeftnik, H. H., and von Stockar, U., Eds.). Elsevier, Amsterdam, 1992, 725\u2013732","DOI":"10.1016\/B978-0-444-89046-7.50104-1"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB13","unstructured":"Cheryan, M. Ultrafiltration Handbook. Technomic Publishing Company, Inc. Lancaster, PA"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB14","doi-asserted-by":"crossref","unstructured":"Serralheiro, M. L. M., and Cabral, J. M. S. Influence of long chain alcohol and chemical modification on the microencapsulated \u03b1-chymotrypsin stability. In: Stability and Stabilization of Enzymes (van den Tweel, W. J. J., Harder, A., and Buitelaar, R. M., Eds.). Elsevier, Amsterdam, 1993, 481\u2013488","DOI":"10.1016\/B978-0-444-89372-7.50063-4"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB15","doi-asserted-by":"crossref","unstructured":"Florsheimer, A., Kula, M.-R., Schutz, H.-J., and Wandrey, C. Continuous production of kyotorphin. Biotechnol. Bioeng. 1989, 33, 1400\u20131405","DOI":"10.1002\/bit.260331106"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB16","doi-asserted-by":"crossref","unstructured":"Fischer, A., Bommarius, A. S., Drauz, K., and Wandrey, C. A novel approach to enzymatic peptide synthesis using highly solubilizing N\u03b1-protecting groups of amino acids. Biocatalysis 1994, 8, 289\u2013307","DOI":"10.3109\/10242429408998213"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB17","doi-asserted-by":"crossref","unstructured":"Schwarz, A., Wandrey, C., Steinke, D., and Kula, M. R. A two-step enzymatic synthesis of dipeptide. Biotechnol. Bioeng. 1992, 39, 132\u2013140","DOI":"10.1002\/bit.260390203"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB18","unstructured":"Herrmann, G., Schwarz, A., Wandrey, C., Kula, M.-R., Knaup, G., Dreuz, K. H., and Berndt, A. A scale-up of enzymatic peptide synthesis in an enzyme membrane reactor. Biotechnol. Appl. Biochem. 1991, 13, 346\u2013353"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB19","doi-asserted-by":"crossref","unstructured":"Nagayasu, T., Miyanaga, M., Tanaka, T., Sakiyama, T., and Nakanishi, K. Synthesis of aspartame precursor with an immobilized thermolysin in tert-amyl alcohol. Biotechnol. Bioeng. 1994, 43, 1118\u20131123","DOI":"10.1002\/bit.260431116"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB20","doi-asserted-by":"crossref","unstructured":"Richards, A. O., Gill, I. S., and Vulfson, E. N. Continuous enzymatic production of oligopeptides: synthesis of an enkephalin pentapeptide in a multistage bioreactor. Enzyme Microb. Technol. 1993, 15, 928\u2013935","DOI":"10.1016\/0141-0229(93)90168-2"},{"key":"10.1016\/S0141-0229(98)00141-0_BIB21","unstructured":"Wiseman, A. Stabilization of enzymes. In: Topics in Enzyme and Fermentation Technology Vol. 2 (Wiseman, A., Ed.). Ellis-Horwiid Publishers, 1978, 280\u2013303"}],"container-title":["Enzyme and Microbial Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141022998001410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141022998001410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T00:01:07Z","timestamp":1555977667000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141022998001410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,6]]},"references-count":21,"journal-issue":{"issue":"8-9","published-print":{"date-parts":[[1999,6]]}},"alternative-id":["S0141022998001410"],"URL":"https:\/\/doi.org\/10.1016\/s0141-0229(98)00141-0","relation":{},"ISSN":["0141-0229"],"issn-type":[{"value":"0141-0229","type":"print"}],"subject":[],"published":{"date-parts":[[1999,6]]}}}