{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T14:50:29Z","timestamp":1770475829835,"version":"3.49.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"1-2","license":[{"start":{"date-parts":[[2002,3,1]],"date-time":"2002-03-01T00:00:00Z","timestamp":1014940800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4156,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mechanisms of Development"],"published-print":{"date-parts":[[2002,3]]},"DOI":"10.1016\/s0925-4773(01)00640-2","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T10:34:40Z","timestamp":1027593280000},"page":"69-77","source":"Crossref","is-referenced-by-count":89,"title":["Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia"],"prefix":"10.1016","volume":"112","author":[{"given":"Albert","family":"Gr\u00fcnder","sequence":"first","affiliation":[]},{"given":"Thorsten T.","family":"Ebel","sequence":"additional","affiliation":[]},{"given":"Mois\u00e9s","family":"Mallo","sequence":"additional","affiliation":[]},{"given":"Georg","family":"Schwarzkopf","sequence":"additional","affiliation":[]},{"given":"Takehiko","family":"Shimizu","sequence":"additional","affiliation":[]},{"given":"Albrecht E.","family":"Sippel","sequence":"additional","affiliation":[]},{"given":"Heinrich","family":"Schrewe","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0925-4773(01)00640-2_BIB1","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0092-8674(94)90522-3","article-title":"HNF-3 beta is essential for node and notochord formation in mouse development","volume":"78","author":"Ang","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB2","doi-asserted-by":"crossref","first-page":"32759","DOI":"10.1074\/jbc.272.52.32759","article-title":"Nuclear factor I family members regulate the transcription of surfactant protein-C","volume":"272","author":"Bachurski","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1242\/dev.124.1.53","article-title":"Involvement of sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis","volume":"124","author":"Bellusci","year":"1997","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB4","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/8792","article-title":"Sox9 is required for cartilage formation","volume":"22","author":"Bi","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB5","doi-asserted-by":"crossref","first-page":"6698","DOI":"10.1073\/pnas.111092198","article-title":"Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization","volume":"98","author":"Bi","year":"2001","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB6","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1203\/00006450-199309000-00019","article-title":"The formation of alveoli in rat lung during the third and fourth postnatal weeks: effect of hyperoxia, dexamethasone, and deferoxamine","volume":"34","author":"Blanco","year":"1993","journal-title":"Pediatr. Res."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB7","doi-asserted-by":"crossref","first-page":"4295","DOI":"10.1093\/nar\/12.10.4295","article-title":"The TGGA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double-stranded linear DNA","volume":"12","author":"Borgmeyer","year":"1984","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB8","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1093\/emboj\/19.4.655","article-title":"Transcription factor Sp3 is essential for post-natal survival and late tooth development","volume":"19","author":"Bouwman","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB9","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/(SICI)1097-0177(199703)208:3<313::AID-AJA3>3.0.CO;2-L","article-title":"Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development","volume":"208","author":"Chaudhry","year":"1997","journal-title":"Dev. Dyn."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB10","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1242\/dev.128.11.2095","article-title":"Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme","volume":"128","author":"Colvin","year":"2001","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB11","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/0092-8674(93)90627-3","article-title":"Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity","volume":"75","author":"Echelard","year":"1993","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB12","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1242\/dev.126.2.281","article-title":"Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms","volume":"126","author":"Epstein","year":"1999","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0378-1119(00)00140-2","article-title":"Roles of the NFI\/CTF gene family in transcription and development","volume":"249","author":"Gronostajski","year":"2000","journal-title":"Gene"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB14","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0378-1119(95)00460-N","article-title":"Molecular organization of the gene encoding murine transforming growth factor \u03b21","volume":"165","author":"Guron","year":"1995","journal-title":"Gene"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB15","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1242\/dev.109.1.29","article-title":"Colocalization of TGF-\u03b2 1 and collagen I and III, fibronectin and glycosaminoglycans during lung branching morphogenesis","volume":"109","author":"Heine","year":"1990","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/ng1295-415","article-title":"Abnormal lung development and cleft palate in mice lacking TGF-\u03b23 indicates defects of epithelial\u2013mesenchymal interaction","volume":"11","author":"Kaartinen","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB17","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1242\/dev.125.14.2587","article-title":"Hoxa2 restricts the chondrogenic domain and inhibits bone formation during development of the branchial arches","volume":"125","author":"Kanzler","year":"1998","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB18","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1242\/dev.127.5.1095","article-title":"BMP signaling is essential for development of skeletogenic and neurogenic cranial neural crest","volume":"127","author":"Kanzler","year":"2000","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB19","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/S0022-3476(96)70355-4","article-title":"Increase in the concentration of transforming growth factor beta-1 in bronchoalveolar lavage fluid before development of chronic lung disease of prematurity","volume":"128","author":"Kotecha","year":"1996","journal-title":"J. Pediatr."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB20","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0014-5793(94)00585-0","article-title":"Transcription factor nuclear factor I proteins form stable homo- and heterodimers","volume":"348","author":"Kruse","year":"1994","journal-title":"FEBS Lett."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB21","doi-asserted-by":"crossref","first-page":"6641","DOI":"10.1093\/nar\/19.23.6641","article-title":"Identification of a fourth nuclear factor I gene in chicken by cDNA cloning: NFI-X","volume":"19","author":"Kruse","year":"1991","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB22","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1002\/j.1460-2075.1986.tb04223.x","article-title":"Functional homology between the sequence-specific DNA-binding proteins nuclear factor I from HeLa cells and the TGGCA protein from chicken liver","volume":"5","author":"Leegwater","year":"1986","journal-title":"EMBO J."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB23","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1242\/dev.124.20.3943","article-title":"Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development","volume":"124","author":"Lindahl","year":"1997","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB24","series-title":"Genetic Variants and Strains of the Laboratory Mouse","author":"Lyon","year":"1989"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB25","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1242\/dev.128.2.155","article-title":"The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm","volume":"128","author":"Mahlapuu","year":"2001","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB26","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/0076-6879(93)25050-C","article-title":"Surgical techniques in production of transgenic mice","volume":"255","author":"Mann","year":"1993","journal-title":"Methods Enzymol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB27","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1006\/dbio.1997.8593","article-title":"Impaired lung branching morphogenesis in the absence of functional EGF receptor","volume":"186","author":"Miettinen","year":"1997","journal-title":"Dev. Biol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB28","doi-asserted-by":"crossref","first-page":"6438","DOI":"10.1073\/pnas.79.21.6438","article-title":"Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex","volume":"79","author":"Nagata","year":"1982","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB29","doi-asserted-by":"crossref","first-page":"6177","DOI":"10.1073\/pnas.80.20.6177","article-title":"Specific binding of cellular DNA replication protein to the origin of repliction of adenovirus DNA","volume":"80","author":"Nagata","year":"1983","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB30","first-page":"770","article-title":"Two large insert vectors, \u03bbPS and lambda \u03bbKO, facilitate rapid mapping and targeted disruption of mammalian genes","volume":"17","author":"Nehls","year":"1994","journal-title":"Biotechniques"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB31","doi-asserted-by":"crossref","first-page":"11946","DOI":"10.1073\/pnas.96.21.11946","article-title":"Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of the corpus callosum","volume":"96","author":"das Neves","year":"1999","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB32","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/0092-8674(82)90257-4","article-title":"Specific protein-DNA interaction at four sites flanking the chicken lysozyme gene","volume":"30","author":"Nowock","year":"1982","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB33","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1093\/nar\/13.6.2045","article-title":"The TGGCA protein binds to the MMTV-LTR, the adenovirus origin of replication, and the BK virus enhancer","volume":"13","author":"Nowock","year":"1985","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB34","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1515\/BC.1999.077","article-title":"Monoallelic expression of Pax5: a paradigm for the haploinsufficiency of mammalian Pax genes?","volume":"380","author":"Nutt","year":"1999","journal-title":"Biol. Chem."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB35","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1242\/dev.110.2.609","article-title":"In situ hybridization analysis of TGF\u03b23 RNA expression during mouse development: comparative studies with TGF\u03b21 and TGF\u03b22","volume":"110","author":"Pelton","year":"1990","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB36","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1165\/ajrcmb\/5.6.522","article-title":"Expression of transforming growth factor-\u03b21, -\u03b22, and -\u03b23 mRNA and protein in the murine lung","volume":"5","author":"Pelton","year":"1991","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB37","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0960-9822(98)70446-4","article-title":"Sonic hedgehog regulates branching morphogenesis in the mammalian lung","volume":"8","author":"Pepicelli","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB38","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1002\/j.1460-2075.1994.tb06631.x","article-title":"Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung","volume":"13","author":"Peters","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB39","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0076-6879(93)25054-6","article-title":"Gene targeting in embryonic stem cells","volume":"255","author":"Ram\u0131&#x0301;rez-Solis","year":"1993","journal-title":"Methods Enzymol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB40","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1093\/nar\/18.9.2607","article-title":"Chicken NFI\/TGGCA proteins are encoded by at least three independent genes: NFI-A, NFI-B and NFI-C with homologues in mammalian genomes","volume":"18","author":"Rupp","year":"1990","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB41","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0925-4773(94)90094-9","article-title":"Mice homozygous for a null mutation of activin \u03b2B are viable and fertile","volume":"47","author":"Schrewe","year":"1994","journal-title":"Mech. Dev."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB42","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/0092-8674(91)90012-N","article-title":"Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations","volume":"65","author":"Schwartzberg","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB43","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1242\/dev.120.8.2153","article-title":"TGF\u03b21 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures","volume":"120","author":"Serra","year":"1994","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB44","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1101\/gad.7.11.2071","article-title":"Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20","volume":"7","author":"Swiatek","year":"1993","journal-title":"Genes Dev."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB45","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3109\/01902149109064406","article-title":"Lung development in the mouse embryo","volume":"17","author":"Ten Have-Opbroek","year":"1991","journal-title":"Exp. Lung Res."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB46","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0095-5108(18)30443-3","article-title":"Prematurity and the developing lung","volume":"19","author":"Thurlbeck","year":"1992","journal-title":"Clin. Perinatol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB47","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1006\/dbio.1996.0266","article-title":"Local delivery of TGF\u03b22 can substitute for the placode epithelium to induce mesenchymal condensation during skin appendage morphogenesis","volume":"179","author":"Ting-Berreth","year":"1996","journal-title":"Dev. Biol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB48","doi-asserted-by":"crossref","first-page":"3615","DOI":"10.1242\/dev.125.18.3615","article-title":"FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung","volume":"125","author":"Weinstein","year":"1998","journal-title":"Development"},{"key":"10.1016\/S0925-4773(01)00640-2_BIB49","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/dvdy.1140","article-title":"TGF-\u03b21 perturbs vascular development and inhibits epithelial differentiation in fetal lung in vivo","volume":"221","author":"Zeng","year":"2001","journal-title":"Dev. Dyn."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB50","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1006\/dbio.1996.0298","article-title":"Abrogation of transforming growth factor-\u03b2 type II receptor stimulates embryonic mouse lung branching morphogenesis in culture","volume":"180","author":"Zhao","year":"1996","journal-title":"Dev. Biol."},{"key":"10.1016\/S0925-4773(01)00640-2_BIB51","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1006\/dbio.1996.0110","article-title":"Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-\u03b21 chimeric gene","volume":"175","author":"Zhou","year":"1996","journal-title":"Dev. Biol."}],"container-title":["Mechanisms of Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925477301006402?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925477301006402?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T14:23:07Z","timestamp":1620138187000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925477301006402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,3]]},"references-count":51,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2002,3]]}},"alternative-id":["S0925477301006402"],"URL":"https:\/\/doi.org\/10.1016\/s0925-4773(01)00640-2","relation":{},"ISSN":["0925-4773"],"issn-type":[{"value":"0925-4773","type":"print"}],"subject":[],"published":{"date-parts":[[2002,3]]}}}