{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T10:21:58Z","timestamp":1772533318267,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2003,8,1]],"date-time":"2003-08-01T00:00:00Z","timestamp":1059696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fish & Shellfish Immunology"],"published-print":{"date-parts":[[2003,8]]},"DOI":"10.1016\/s1050-4648(02)00144-4","type":"journal-article","created":{"date-parts":[[2003,4,23]],"date-time":"2003-04-23T20:36:00Z","timestamp":1051130160000},"page":"129-144","source":"Crossref","is-referenced-by-count":68,"title":["Apoptosis of sea bass (Dicentrarchus labrax L.) neutrophils and macrophages induced by experimental infection with Photobacterium damselae subsp. piscicida"],"prefix":"10.1016","volume":"15","author":[{"given":"Ana","family":"do Vale","sequence":"first","affiliation":[]},{"given":"Fernanda","family":"Marques","sequence":"additional","affiliation":[]},{"given":"Manuel T","family":"Silva","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S1050-4648(02)00144-4_BIB1","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/35037728","article-title":"CD95's deadly mission in the immune system","volume":"407","author":"Krammer","year":"2000","journal-title":"Nature"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB2","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/35037734","article-title":"Apoptosis in development","volume":"407","author":"Meier","year":"2000","journal-title":"Nature"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0092-8674(00)81873-5","article-title":"Programmed cell death in animal development","volume":"88","author":"Jacobson","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s004410000193","article-title":"The morphology of apoptosis","volume":"301","author":"Hacker","year":"2000","journal-title":"Cell Tissue Res"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0074-7696(08)62312-8","article-title":"Cell death: the significance of apoptosis","volume":"68","author":"Wyllie","year":"1980","journal-title":"Int Rev Cytol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB6","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1146\/annurev.iy.10.040192.001411","article-title":"Apoptosis and programmed cell death in immunity","volume":"10","author":"Cohen","year":"1992","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB7","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0074-7696(08)62419-5","article-title":"The regulation of apoptosis by microbial pathogens","volume":"187","author":"Moss","year":"1999","journal-title":"Int Rev Cytol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB8","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1128\/IAI.68.1.342-351.2000","article-title":"In vitro Brucella suis infection prevents the programmed cell death of human monocytic cells","volume":"68","author":"Gross","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB9","doi-asserted-by":"crossref","first-page":"4646","DOI":"10.1073\/pnas.95.8.4646","article-title":"NF-kappa B-dependent inhibition of apoptosis is essential for host cell survival during Rickettsia rickettsii infection","volume":"95","author":"Clifton","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB10","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1084\/jem.187.4.487","article-title":"Inhibition of apoptosis in chlamydia-infected cells: blockade of mitochondrial cytochrome c release and caspase activation","volume":"187","author":"Fan","year":"1998","journal-title":"J Exp Med"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.micro.53.1.155","article-title":"The induction of apoptosis by bacterial pathogens","volume":"53","author":"Weinrauch","year":"1999","journal-title":"Annu Rev Microbiol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0959-8030(93)90028-A","article-title":"Pathogenesis of Gram-negative bacterial infections in warmwater fish","author":"Thune","year":"1993","journal-title":"Annu Rev Fish Dis"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB13","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0959-8030(96)00004-X","article-title":"Phenotypic and pathobiological characteristics of Pasteurella piscicida","volume":"6","author":"Magari\u00f1os","year":"1996","journal-title":"Annu Rev Fish Dis"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB14","unstructured":"Romalde JL, Magari\u00f1os B. Immunization with bacterial antigens: pasteurellosis. In: Gudding R, Lillehaug A, Midtlyng PJ, Brown F, editors. Karger, Basel. Fish Vaccinology. 1997. p. 167\u201377."},{"key":"10.1016\/S1050-4648(02)00144-4_BIB15","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1099\/00221287-138-12-2491","article-title":"Pathogenic activities of live cells and extracellular products of the fish pathogen Pasteurella piscicida","volume":"138","author":"Magari\u00f1os","year":"1992","journal-title":"J Gen Microbiol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB16","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1006\/fsim.1997.0089","article-title":"The leukocyte population of the unstimulated peritoneal cavity of rainbow trout (Oncorhynchus mykiss)","volume":"7","author":"Afonso","year":"1997","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB17","article-title":"The professional phagocytes of sea bass (Dicentrarchus labrax L.): cytochemical characterisation of neutrophils and macrophages in the normal and inflamed peritoneal cavity","volume":"12","author":"do Vale","year":"2002","journal-title":"Fish Shellfish Immunol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB18","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3354\/dao034027","article-title":"Neutrophil and macrophage responses to inflammation in the peritoneal cavity of rainbow trout Oncorhynchus mykiss. A light and electron microscopic cytochemical study","volume":"34","author":"Afonso","year":"1998","journal-title":"Dis Aquat Organ"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB19","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1128\/IAI.55.9.2006-2016.1987","article-title":"In vivo killing and degradation of Mycobacterium aurum within mouse peritoneal macrophages","volume":"55","author":"Silva","year":"1987","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB20","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1006\/excr.2000.4834","article-title":"Apoptotic DNA fragmentation","volume":"256","author":"Nagata","year":"2000","journal-title":"Exp Cell Res"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB21","series-title":"Molecular cloning. A laboratory manual","author":"Sambrook","year":"2001"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB22","series-title":"Techniques in fish immunology","first-page":"137","article-title":"Isolation of salmonid macrophages and analysis of their killing activity","author":"Secombes","year":"1990"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB23","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/358167a0","article-title":"Shigella flexneri induces apoptosis in infected macrophages","volume":"358","author":"Zychlinsky","year":"1992","journal-title":"Nature"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB24","doi-asserted-by":"crossref","first-page":"5357","DOI":"10.1128\/IAI.64.12.5357-5365.1996","article-title":"In vivo apoptosis in Shigella flexneri infections","volume":"64","author":"Zychlinsky","year":"1996","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB25","doi-asserted-by":"crossref","first-page":"9833","DOI":"10.1073\/pnas.93.18.9833","article-title":"Salmonella typhimurium invasion induces apoptosis in infected macrophages","volume":"93","author":"Monack","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB26","doi-asserted-by":"crossref","first-page":"4813","DOI":"10.1128\/IAI.65.11.4813-4821.1997","article-title":"Interaction of Yersinia enterocolitica with macrophages leads to macrophage cell death through apoptosis","volume":"65","author":"Ruckdeschel","year":"1997","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB27","doi-asserted-by":"crossref","first-page":"4900","DOI":"10.1128\/IAI.64.12.4900-4906.1996","article-title":"Evidence for apoptosis of human macrophage-like HL-60 cells by Legionella pneumophila infection","volume":"64","author":"Muller","year":"1996","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB28","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1099\/00221287-146-10-2521","article-title":"Secreted products of a nonmucoid Pseudomonas aeruginosa strain induce two modes of macrophage killing: external-ATP-dependent, P2Z-receptor-mediated necrosis and ATP-independent, caspase-mediated apoptosis","volume":"146","author":"Zaborina","year":"2000","journal-title":"Microbiology"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB29","doi-asserted-by":"crossref","first-page":"5530","DOI":"10.1128\/IAI.67.10.5530-5537.1999","article-title":"Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells","volume":"67","author":"Hauser","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB30","doi-asserted-by":"crossref","first-page":"3914","DOI":"10.1128\/IAI.63.10.3914-3919.1995","article-title":"Evidence for apoptosis of murine macrophages by Actinobacillus actinomycetemcomitans infection","volume":"63","author":"Kato","year":"1995","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB31","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1128\/IAI.68.4.1893-1898.2000","article-title":"Induction of apoptotic cell death in peripheral blood mononuclear and polymorphonuclear cells by an oral bacterium, Fusobacterium nucleatum","volume":"68","author":"Jewett","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB32","doi-asserted-by":"crossref","first-page":"4064","DOI":"10.1128\/IAI.61.10.4064-4071.1993","article-title":"Bordetella pertussis induces apoptosis in macrophages: role of adenylate cyclase-hemolysin","volume":"61","author":"Khelef","year":"1993","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB33","doi-asserted-by":"crossref","first-page":"3923","DOI":"10.4049\/jimmunol.165.7.3923","article-title":"Group B Streptococcus induces apoptosis in macrophages","volume":"165","author":"Fettucciari","year":"2000","journal-title":"J Immunol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB34","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1128\/IAI.69.3.1287-1297.2001","article-title":"Fas (CD95)-Fas ligand interactions are responsible for monocyte apoptosis occurring as a result of phagocytosis and killing of Staphylococcus aureus","volume":"69","author":"Baran","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB35","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1006\/mpat.1998.0205","article-title":"Apoptosis: a possible tactic of Haemophilus somnus for evasion of killing by bovine neutrophils?","volume":"24","author":"Yang","year":"1998","journal-title":"Microb Pathog"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB36","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.4049\/jimmunol.168.4.1861","article-title":"Induction of neutrophil apoptosis by the Pseudomonas aeruginosa exotoxin pyocyanin: a potential mechanism of persistent infection","volume":"168","author":"Usher","year":"2002","journal-title":"J Immunol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB37","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1099\/00221287-146-1-21","article-title":"Invasion of fish epithelial cells by Photobacterium damselae subsp. piscicida: evidence for receptor specificity, and effect of capsule and serum","volume":"146","author":"Lopez-Doriga","year":"2000","journal-title":"Microbiology"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB38","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3354\/dao023051","article-title":"In vitro killing of Pasteurella piscicida by fish macrophages","volume":"23","author":"Skarmeta","year":"1995","journal-title":"Dis Aquat Organ"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB39","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1099\/13500872-145-2-483","article-title":"Superoxide dismutase and catalase in Photobacterium damselae subsp. piscicida and their roles in resistance to reactive oxygen species","volume":"145","author":"Barnes","year":"1999","journal-title":"Microbiology"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB40","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1172\/JCI113970","article-title":"Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages","volume":"83","author":"Savill","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB41","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.4049\/jimmunol.157.7.3105","article-title":"Sequential morphologic events during apoptosis of human neutrophils. Modulation by lipoxygenase-derived eicosanoids","volume":"157","author":"Hebert","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB42","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1172\/JCI112869","article-title":"Tissue injury in inflammation. Oxidants, proteases and cationic proteins","volume":"79","author":"Henson","year":"1987","journal-title":"J Clin Invest"},{"key":"10.1016\/S1050-4648(02)00144-4_BIB43","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/jlb.66.1.10","article-title":"Neutrophil migration during endotoxemia","volume":"66","author":"Wagner","year":"1999","journal-title":"J Leukoc Biol"}],"container-title":["Fish & Shellfish Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464802001444?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1050464802001444?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T06:18:26Z","timestamp":1682489906000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1050464802001444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["S1050464802001444"],"URL":"https:\/\/doi.org\/10.1016\/s1050-4648(02)00144-4","relation":{},"ISSN":["1050-4648"],"issn-type":[{"value":"1050-4648","type":"print"}],"subject":[],"published":{"date-parts":[[2003,8]]}}}