{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T01:54:55Z","timestamp":1772762095708,"version":"3.50.1"},"reference-count":26,"publisher":"Hindawi Limited","issue":"1","license":[{"start":{"date-parts":[[2009,4,14]],"date-time":"2009-04-14T00:00:00Z","timestamp":1239667200000},"content-version":"unspecified","delay-in-days":7377,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genet. Res."],"published-print":{"date-parts":[[1989,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Little information exists about the mechanisms that determine the fate of mobile elements in natural populations. In this study we catalogue the distribution of 638 P-elements across 114<jats:italic>X<\/jats:italic>chromosomes in samples drawn from three natural populations of<jats:italic>Drosophila melanogaster<\/jats:italic>. There is an extremely high occurrence of elements at the tip relative to the rest of the euchromatic chromosome. We demonstrate that the distribution of<jats:italic>de novo<\/jats:italic>insertions of the P-element on a specific laboratory chromosome is markedly different; no P-elements were recovered at the tip in the 243 insertion events recorded. In contrast, insertion data for the \u03c0<jats:sup>2<\/jats:sup>chromosome suggests an elevated rate associated with the tip site although it does not appear sufficient to explain the large differential accumulation on wild chromosomes. This raises the issue of inter chromosome (or tip) variation in relative rates, as well as the possibility that rates of elimination are lower at the tip.<\/jats:p>","DOI":"10.1017\/s0016672300027798","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T07:34:22Z","timestamp":1253172862000},"page":"1-6","source":"Crossref","is-referenced-by-count":39,"title":["The accumulation of P-elements on the tip of the<i>X<\/i>chromosome in populations of<i>Drosophila melanogaster<\/i>"],"prefix":"10.1155","volume":"53","author":[{"given":"James W.","family":"Ajioka","sequence":"first","affiliation":[]},{"given":"Walter F.","family":"Eanes","sequence":"additional","affiliation":[]}],"member":"98","published-online":{"date-parts":[[2009,4,14]]},"reference":[{"key":"S0016672300027798_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(82)90463-9"},{"key":"S0016672300027798_ref003","doi-asserted-by":"crossref","first-page":"4125","DOI":"10.1002\/j.1460-2075.1987.tb02758.x","article-title":"KP elements repress P-induced hybrid dysgenesis in Drosophila melanogaster","volume":"6","author":"Black","year":"1987","journal-title":"EMBO Journal"},{"key":"S0016672300027798_ref014","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.6.1655"},{"key":"S0016672300027798_ref012","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.16.5017"},{"key":"S0016672300027798_ref009","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ge.17.120183.001531"},{"key":"S0016672300027798_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300027269"},{"key":"S0016672300027798_ref020","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300026707"},{"key":"S0016672300027798_ref001","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.16.5418"},{"key":"S0016672300027798_ref004","doi-asserted-by":"publisher","DOI":"10.1126\/science.6766221"},{"key":"S0016672300027798_ref021","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/genetics\/104.3.473","article-title":"Transposable elements in Mendelian popluations. II. Distribution of three copia-like elements in a natural population of Drosophila melanogaster","volume":"104","author":"Montgomery","year":"1983","journal-title":"Genetics"},{"key":"S0016672300027798_ref013","doi-asserted-by":"publisher","DOI":"10.1016\/0040-5809(83)90018-7"},{"key":"S0016672300027798_ref019","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.7.2051"},{"key":"S0016672300027798_ref007","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.1.174"},{"key":"S0016672300027798_ref006","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300021455"},{"key":"S0016672300027798_ref016","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300027695"},{"key":"S0016672300027798_ref022","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.21.7605"},{"key":"S0016672300027798_ref015","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.14.4381"},{"key":"S0016672300027798_ref023","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(83)90133-2"},{"key":"S0016672300027798_ref026","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(82)90462-7"},{"key":"S0016672300027798_ref011","first-page":"1","article-title":"Transposable elements in Drosophila melanogaster","volume":"3","author":"Finnegan","year":"1986","journal-title":"Oxford Surveys on Eukaryotic Genes"},{"key":"S0016672300027798_ref018","volume-title":"Genetic variations of Drosophila melanogaster","author":"Lindsley","year":"1968"},{"key":"S0016672300027798_ref024","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1093\/genetics\/92.3.861","article-title":"Rapid change of chromomeric and pairing patterns of polytene chromosome tips in D. melanogaster: Migration of Polytene\u2013non-polytene transition zone?","volume":"92","author":"Roberts","year":"1979","journal-title":"Genetics"},{"key":"S0016672300027798_ref025","doi-asserted-by":"publisher","DOI":"10.1007\/BF00292752"},{"key":"S0016672300027798_ref005","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.jhered.a104399"},{"key":"S0016672300027798_ref010","volume-title":"Mobile DNA","author":"Engels","year":"1988"},{"key":"S0016672300027798_ref017","doi-asserted-by":"publisher","DOI":"10.1017\/S0016672300026914"}],"container-title":["Genetical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0016672300027798","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T22:44:57Z","timestamp":1633905897000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0016672300027798\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,2]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1989,2]]}},"alternative-id":["S0016672300027798"],"URL":"https:\/\/doi.org\/10.1017\/s0016672300027798","relation":{},"ISSN":["0016-6723","1469-5073"],"issn-type":[{"value":"0016-6723","type":"print"},{"value":"1469-5073","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,2]]}}}