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Haemagglutination-inhibition tests revealed a high prevalence of antibodies to Zika and three other flaviviruses used. The percentages of positive sera were as follows: Zika (31%), Yellow fever (50%), West Nile (46%), and Wesselsbron (59%). Neutralization tests showed that 40% of Nigerians had Zika virus neutralizing antibody. Fifty per cent of Zika virus immune persons had neutralizing antibody to Zika alone or to Zika and one other flavivirus. A total of 121 sera had antibody to Zika virus; of these 48 (40%) also showed antibody to two other flaviviruses, and 12 (10%) had antibodies to three or more other viruses. The percentage of neutralizing antibodies to other flaviviruses in Zika virus immune sera was 81% to Dengue type 1, 58% to Yellow fever, 7% to Wesselsbron, 6% to West Nile and 3% to Uganda S.<\/jats:p>","DOI":"10.1017\/s0022172400025997","type":"journal-article","created":{"date-parts":[[2009,5,15]],"date-time":"2009-05-15T09:40:32Z","timestamp":1242380432000},"page":"213-219","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":248,"title":["Zika virus infections in Nigeria: virological and seroepidemiological investigations in Oyo State"],"prefix":"10.1017","volume":"83","author":[{"given":"A. 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