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Eighty per cent of the sample were examined, using the Hierarchic Dementia Scale to test cognitive functioning and the CAMDEX criteria to assess global clinical severity. Repeat assessment after a mean interval of 27 months showed that all new cases of clinical dementia had arisen in persons with mild deficits initially and represented one-fifth of this group. The first-assessment ratings of cognitive function proved to be strongly predictive of risks for age-corrected mortality, admission to long-term care and dependency at follow-up, as well as of further progressive cognitive decline.<\/jats:p>","DOI":"10.1017\/s0033291700034802","type":"journal-article","created":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T13:40:37Z","timestamp":1247146837000},"page":"411-419","source":"Crossref","is-referenced-by-count":33,"title":["Early development and progression of dementing illness in the elderly: a general-practice based study"],"prefix":"10.1017","volume":"26","author":[{"given":"B.","family":"Cooper","sequence":"first","affiliation":[]},{"given":"H.","family":"Bickel","sequence":"additional","affiliation":[]},{"given":"M.","family":"Sch\u00e4ufele","sequence":"additional","affiliation":[]}],"member":"56","published-online":{"date-parts":[[2009,7,9]]},"reference":[{"volume-title":"Wechsler Memory Scale \u2013 Revised","year":"1987","author":"Wechsler","key":"S0033291700034802_ref026"},{"key":"S0033291700034802_ref017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1991.tb05509.x"},{"key":"S0033291700034802_ref008","doi-asserted-by":"publisher","DOI":"10.1002\/gps.930070809"},{"key":"S0033291700034802_ref019","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.5.867"},{"key":"S0033291700034802_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(87)72519-5"},{"key":"S0033291700034802_ref015","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.8.1427"},{"key":"S0033291700034802_ref012","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.7.1006"},{"key":"S0033291700034802_ref016","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.153.3.328"},{"key":"S0033291700034802_ref003","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.114.512.797"},{"key":"S0033291700034802_ref010","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables","volume":"34","author":"Cox","year":"1972","journal-title":"Journal of the Royal Statistical Society"},{"key":"S0033291700034802_ref020","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113963"},{"key":"S0033291700034802_ref001","doi-asserted-by":"publisher","DOI":"10.1002\/gps.930060506"},{"key":"S0033291700034802_ref002","first-page":"253","volume-title":"Primary Health Care and Psychiatric Epidemiology","author":"Bickel","year":"1992"},{"volume-title":"International Classification of Impairments, Disabilities and Handicaps (ICIDH)","year":"1980","key":"S0033291700034802_ref028"},{"key":"S0033291700034802_ref018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1991.tb01645.x"},{"key":"S0033291700034802_ref007","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700003093"},{"key":"S0033291700034802_ref024","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610292001157"},{"key":"S0033291700034802_ref004","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1991.tb05904.x"},{"key":"S0033291700034802_ref005","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.3.2.147"},{"key":"S0033291700034802_ref009","first-page":"551","article-title":"Demenzerkrankungen und leichtere kognitive Beeintr\u00e4chtigung bei \u00e4lteren Patienten in der \u00e4rztlichen Allgemeinpraxis. 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