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Most components of the mitochondrial respiratory chain contain transition metals, and these elements and their chemical environment can often be studied by modern spectroscopic methods, such as electron-paramagnetic resonance (EPR). The relation between spectroscopic properties and chemical structure of metallo-proteins, e.g. haem proteins, represents one of the few branches of present-day biochemistry to which quantum mechanical calculations can profitably be applied (see, for example, Zerner, Gouterman &amp; Kobayashi, 1966).<\/jats:p>","DOI":"10.1017\/s0033583500001578","type":"journal-article","created":{"date-parts":[[2009,3,17]],"date-time":"2009-03-17T16:23:13Z","timestamp":1237306993000},"page":"389-431","source":"Crossref","is-referenced-by-count":140,"title":["Cytochrome<i>c<\/i>oxidase: some current biochemical and biophysical problems"],"prefix":"10.1017","volume":"6","author":[{"given":"Bo G.","family":"Malmstr\u00f6m","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,3,17]]},"reference":[{"key":"S0033583500001578_ref023","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0021-9258(18)96936-X","article-title":"Isolation of sperm whale myoglobin by low temperature fractionation with ethanol and metallic ions","volume":"241","author":"Hardman","year":"1966","journal-title":"J. biol. 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