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Rigid tools used in traditional approaches limit the surgeons' ability to comprehensively treat the osteolysis due to the complex geometries of the lesion. The surgical scenario, testing, kinematic modeling, and image-based inverse kinematics are described. Testing shows 94% coverage of a lesion wall; the kinematic model describes manipulator notch positions within 0.15 mm, while the image-based inverse kinematics has 0.36 mm error. This manipulator is potentially useful in treating osteolytic lesions through (1) effective lesion exploration compared to conventional techniques, and (2) rapidly performing inverse kinematics from visual feedback.<\/jats:p>","DOI":"10.1017\/s0263574713001082","type":"journal-article","created":{"date-parts":[[2013,12,3]],"date-time":"2013-12-03T15:13:19Z","timestamp":1386083599000},"page":"835-850","source":"Crossref","is-referenced-by-count":60,"title":["Design and kinematic characterization of a surgical manipulator with a focus on treating osteolysis"],"prefix":"10.1017","volume":"32","author":[{"given":"Ryan J.","family":"Murphy","sequence":"first","affiliation":[]},{"given":"Michael D. 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