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Referring to hand opening disabilities, the authors have developed a methodology which, by starting from the geometrical characteristics of the patient's hand, defines the novel kinematic mechanism that better fits to the finger trajectories. The authors have validated the proposed novel mechanism by carrying out a Hand Exoskeleton System (HES) prototype, based on a single-phalanx mechanism, cable driven. The testing phase of the real prototype with a patient is currently on going.<\/jats:p>","DOI":"10.1017\/s0263574715000879","type":"journal-article","created":{"date-parts":[[2015,11,3]],"date-time":"2015-11-03T09:16:27Z","timestamp":1446542187000},"page":"892-906","source":"Crossref","is-referenced-by-count":16,"title":["Development, design and validation of an assistive device for hand disabilities based on an innovative mechanism"],"prefix":"10.1017","volume":"35","author":[{"given":"Roberto","family":"Conti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedetto","family":"Allotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Meli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Ridolfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,11,3]]},"reference":[{"key":"S0263574715000879_ref15","doi-asserted-by":"publisher","DOI":"10.1017\/S0263574714002288"},{"key":"S0263574715000879_ref5","doi-asserted-by":"crossref","unstructured":"B. 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Sankai , \u201cFive-Fingered Assistive Hand with Mechanical Compliance of Human Finger,\u201d IEEE International Conference on Robotics and Automation ICRA (2008) pp. 718\u2013724."},{"key":"S0263574715000879_ref8","doi-asserted-by":"crossref","unstructured":"A. Wege , K. Kondak and G. Hommel , \u201cMechanical Design and Motion Control of a Hand Exoskeleton for Rehabilitation,\u201d IEEE International Conference Mechatronics and Automation, vol. 1 (2005) pp. 155\u2013159.","DOI":"10.1109\/ICMA.2005.1626539"},{"key":"S0263574715000879_ref17","doi-asserted-by":"publisher","DOI":"10.1109\/TRO.2012.2226381"},{"key":"S0263574715000879_ref4","doi-asserted-by":"crossref","unstructured":"Y. Yihun , R. Miklos , A. Perez-Gracia , D. Reinkensmeyer , K. Denney and E. Wolbrecht , \u201cSingle Degree-of-Freedom Exoskeleton Mechanism Design for Thumb Rehabilitation,\u201d Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBC2012 (2012) pp. 1916\u20131920.","DOI":"10.1109\/EMBC.2012.6346328"},{"key":"S0263574715000879_ref13","doi-asserted-by":"crossref","unstructured":"M. Cempini , S. De Rossi , T. Lenzi , M. Cortese , F. Giovacchini , N. Vitiello and M. 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