{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T08:07:48Z","timestamp":1775117268025,"version":"3.50.1"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"unspecified","delay-in-days":14658,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. j. neurol. sci."],"published-print":{"date-parts":[[1975,8]]},"abstract":"<jats:title>SUMMARY:<\/jats:title><jats:p>Central feedback pathways for motor control were studied by recording EMG responses to sudden upper limb displacements in humans and monkeys using a precision torque motor to generate step load changes. Normal human subjects showed three short-latency EMG responses (Ml, M2 and M3) which appear to correspond to those recorded from trained monkeys. The M2 and M3 components, thought to represent feedback in supraspinal pathways, were significantly increased when the subjects were instructed to actively compensate for the load changes.<\/jats:p><jats:p>Parkinsonian patients with rigidity showed evidence of markedly increased feedback over the interval for the M2 and M3 responses and appeared to have lost the ability to modulate feedback according to the motor task being performed. The results are discussed with reference to recent research on motor control mechanisms in primates and a tentative model for the basis of Parkinsonian rigidity is proposed.<\/jats:p>","DOI":"10.1017\/s0317167100020382","type":"journal-article","created":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T11:31:29Z","timestamp":1469705489000},"page":"285-293","source":"Crossref","is-referenced-by-count":337,"title":["Motor Responses to Sudden Limb Displacements in Primates with Specific CNS Lesions and in Human Patients with Motor System Disorders"],"prefix":"10.1017","volume":"2","author":[{"given":"R.G.","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.G.","family":"Tatton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,9,18]]},"reference":[{"key":"S0317167100020382_ref037","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.34.6.699"},{"key":"S0317167100020382_ref036","first-page":"537","article-title":"Discharge of cerebellar neurons related to two maintained postures and two prompt movements. 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