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Our approach to biomimetic design takes advantage of the large amount of biological knowledge already available in books, journals, and so forth, by performing keyword searches on these existing natural-language sources. Because of the ambiguity and imprecision of natural language, challenges inherent to natural language processing were encountered. One challenge of retrieving relevant cross-domain information involves differences in domain vocabularies, or lexicons. A keyword meaningful to biologists may not occur to engineers. For an example problem that involved cleaning, that is, removing dirt, a biochemist suggested the keyword \u201cdefend.\u201d Defend is not an obvious keyword to most engineers for this problem, nor are the words defend and \u201cclean\/remove\u201d directly related within lexical references. However, previous work showed that biological phenomena retrieved by the keyword defend provided useful stimuli and produced successful concepts for the clean\/remove problem. In this paper, we describe a method to systematically bridge the disparate biology and engineering domains using natural language analysis. For the clean\/remove example, we were able to algorithmically generate several biologically meaningful keywords, including defend, that are not obviously related to the engineering problem. We developed a method to organize and rank the set of biologically meaningful keywords identified, and confirmed that we could achieve similar results for two other examples in encapsulation and microassembly. Although we specifically address cross-domain information retrieval from biology, the bridging process presented in this paper is not limited to biology, and can be used for any other domain given the availability of appropriate domain-specific knowledge sources and references.<\/jats:p>","DOI":"10.1017\/s0890060407070138","type":"journal-article","created":{"date-parts":[[2007,1,22]],"date-time":"2007-01-22T23:24:27Z","timestamp":1169508267000},"page":"45-59","source":"Crossref","is-referenced-by-count":94,"title":["Biomimetic design through natural language analysis to facilitate cross-domain information retrieval"],"prefix":"10.1017","volume":"21","author":[{"given":"IVEY","family":"CHIU","sequence":"first","affiliation":[]},{"given":"L.H.","family":"SHU","sequence":"additional","affiliation":[]}],"member":"56","published-online":{"date-parts":[[2007,1,22]]},"reference":[{"key":"S0890060407070138_ref041","doi-asserted-by":"publisher","DOI":"10.1162\/089120100561683"},{"key":"S0890060407070138_ref016","doi-asserted-by":"publisher","DOI":"10.1016\/S1532-0464(03)00012-1"},{"key":"S0890060407070138_ref055","unstructured":"Ullman, D. 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