{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:26:05Z","timestamp":1760783165388,"version":"3.32.0"},"reference-count":33,"publisher":"Maximum Academic Press","issue":"3-4","license":[{"start":{"date-parts":[[2009,6,2]],"date-time":"2009-06-02T00:00:00Z","timestamp":1243900800000},"content-version":"unspecified","delay-in-days":6088,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Vis Neurosci"],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intracellular injections of Neurobiotin were used to determine whether the major ganglion cell classes of the macaque monkey retina, the magnocellular-projecting parasol, and the parvocellular-projecting midget cells showed evidence of cellular coupling similar to that recently described for cat retinal ganglion cells. Ganglion cells were labeled with the fluorescent dye acridine orange in an <jats:italic>in vitro<\/jats:italic>, isolated retina preparation and were selectively targeted for intracellular injection under direct microscopic control. The macaque midget cells, like the beta cells of the cat's retina, showed no evidence of tracer coupling when injected with Neurobiotin. By contrast, Neurobiotin-filled parasol cells, like cat alpha cells, showed a distinct pattern of tracer coupling to each other (homotypic coupling) and to amacrine cells (heterotypic coupling).<\/jats:p><jats:p>In instances of homotypic coupling, the injected parasol cell was surrounded by a regular array of 3\u20136 neighboring parasol cells. The somata and proximal dendrites of these tracer-coupled cells were lightly labeled and appeared to costratify with the injected cell. Analysis of the nearest-neighbor distances for the parasol cell clusters showed that dendritic-field overlap remained constant as dendritic-field size increased from 100\u2013400 \u03bcm in diameter.<\/jats:p><jats:p>At least two amacrine cell types showed tracer coupling to parasol cells. One amacrine type had a small soma and thin, sparsely branching dendrites that extended for 1\u20132 mm in the inner plexiform layer. A second amacrine type had a relatively large soma, thick main dendrites, and distinct, axon-like processes that extended for at least 2\u20133 mm in the inner plexiform layer. The main dendrites of the large amacrine cells were closely apposed to the dendrites of parasol cells and may be the site of Neurobiotin transfer between the two cell types. We suggest that the tracer coupling between neighboring parasol cells takes place indirectly <jats:italic>via<\/jats:italic> the dendrites of the large amacrine cells and provides a mechanism, absent in midget cells, for increasing parasol cell receptive-field size and luminance contrast sensitivity.<\/jats:p>","DOI":"10.1017\/s0952523800010695","type":"journal-article","created":{"date-parts":[[2009,6,2]],"date-time":"2009-06-02T12:01:33Z","timestamp":1243944093000},"page":"279-290","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":129,"title":["A coupled network for parasol but not midget ganglion cells in the primate retina"],"prefix":"10.48130","volume":"9","author":[{"given":"Dennis M.","family":"Dacey","sequence":"first","affiliation":[]},{"given":"Sarah","family":"Brace","sequence":"additional","affiliation":[]}],"member":"27968","published-online":{"date-parts":[[2009,6,2]]},"reference":[{"doi-asserted-by":"publisher","key":"S0952523800010695_ref031","DOI":"10.1523\/JNEUROSCI.07-05-01574.1987"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref026","DOI":"10.1016\/0304-3940(91)90024-N"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref022","DOI":"10.1002\/cne.902660212"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref020","DOI":"10.1002\/cne.902330107"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref018","DOI":"10.1073\/pnas.85.12.4534"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref017","DOI":"10.1113\/jphysiol.1983.sp014807"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref013","DOI":"10.1002\/cne.903030408"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref009","DOI":"10.1113\/jphysiol.1975.sp011086"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref007","DOI":"10.1002\/cne.903010310"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref005","DOI":"10.1002\/cne.902880106"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref003","DOI":"10.1126\/science.3375811"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref016","DOI":"10.1152\/jn.1983.49.2.350"},{"key":"S0952523800010695_ref021","first-page":"1375","article-title":"Parasol retinal ganglion cells in macaques connect intracellularly to other parasol cells, and to amacrine cells found in the ganglion cell layer","volume":"17","author":"Rodieck","year":"1991","journal-title":"Neuroscience Abstracts"},{"key":"S0952523800010695_ref006","first-page":"535","article-title":"The dopaminergic amacrine cell of the cat's retina","volume":"31","author":"Dacey","year":"1990","journal-title":"Investigative Ophthalmology and Visual Science"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref008","DOI":"10.1523\/JNEUROSCI.06-02-00331.1986"},{"key":"S0952523800010695_ref011","first-page":"273","volume-title":"Progress in Retinal Research","author":"Kaplan","year":"1990"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref029","DOI":"10.1523\/JNEUROSCI.08-09-03383.1988"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref010","DOI":"10.1016\/0006-8993(75)90983-X"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref033","DOI":"10.1002\/cne.902930111"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref015","DOI":"10.1002\/cne.903010305"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref025","DOI":"10.1016\/0306-4522(91)90186-R"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref023","DOI":"10.1016\/0306-4522(88)90284-9"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref032","DOI":"10.1002\/cne.902890308"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref030","DOI":"10.1038\/292344a0"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref012","DOI":"10.1073\/pnas.83.8.2755"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref002","DOI":"10.1113\/jphysiol.1988.sp016959"},{"key":"S0952523800010695_ref019","first-page":"203","volume-title":"Comparative Primate Biology. Neurosciences","author":"Rodieck","year":"1988"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref027","DOI":"10.1098\/rspb.1988.0072"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref004","DOI":"10.1002\/cne.902840210"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref024","DOI":"10.1016\/0166-2236(86)90064-0"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref001","DOI":"10.1111\/j.1460-9568.1991.tb00043.x"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref014","DOI":"10.1126\/science.7268423"},{"doi-asserted-by":"publisher","key":"S0952523800010695_ref028","DOI":"10.1152\/physrev.1991.71.2.447"}],"container-title":["Visual Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0952523800010695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T19:59:51Z","timestamp":1735847991000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0952523800010695\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,10]]},"references-count":33,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[1992,10]]}},"alternative-id":["S0952523800010695"],"URL":"https:\/\/doi.org\/10.1017\/s0952523800010695","relation":{},"ISSN":["0952-5238","1469-8714"],"issn-type":[{"type":"print","value":"0952-5238"},{"type":"electronic","value":"1469-8714"}],"subject":[],"published":{"date-parts":[[1992,10]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 1992","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}