{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T16:43:04Z","timestamp":1648572184671},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2009,12,4]],"date-time":"2009-12-04T00:00:00Z","timestamp":1259884800000},"content-version":"unspecified","delay-in-days":3,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Math. Struct. Comp. Sci."],"published-print":{"date-parts":[[2009,12]]},"abstract":"<jats:p>We consider the structure of the intestinal epithelial tissue and of cell\u2013cell junctions as the biological model inspiring a new class of P systems. First we define the concept of cell polarity, a formal property derived from epithelial cells, which present morphologically and functionally distinct regions of the plasma membrane. Then we show two preliminary results for this new model of computation: on the theoretical side, we show that P systems with cell polarity are computationally (Turing) complete; on the modelling side, we show that the transepithelial movement of glucose from the intestinal lumen into the blood can be described by such a formal system. Finally, we define tissue P systems with cell polarity, where each cell has fixed connections to the neighbouring cells and to the environment, according to both the cell polarity and specific cell\u2013cell junctions.<\/jats:p>","DOI":"10.1017\/s0960129509990156","type":"journal-article","created":{"date-parts":[[2009,12,4]],"date-time":"2009-12-04T08:54:26Z","timestamp":1259916866000},"page":"1141-1160","source":"Crossref","is-referenced-by-count":2,"title":["(Tissue) P systems with cell polarity"],"prefix":"10.1017","volume":"19","author":[{"given":"DANIELA","family":"BESOZZI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NADIA","family":"BUSI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PAOLO","family":"CAZZANIGA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CLAUDIO","family":"FERRETTI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALBERTO","family":"LEPORATI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GIANCARLO","family":"MAURI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DARIO","family":"PESCINI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CLAUDIO","family":"ZANDRON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,12,4]]},"reference":[{"key":"S0960129509990156_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3975(02)00136-6"},{"key":"S0960129509990156_ref20","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-56196-2"},{"key":"S0960129509990156_ref22","first-page":"635","article-title":"P systems on graphs of restricted forms","volume":"60","author":"P\u0103un","year":"2002","journal-title":"Publicationes Mathematicae Debrecen"},{"key":"S0960129509990156_ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s10015-007-0424-1"},{"key":"S0960129509990156_ref25","doi-asserted-by":"publisher","DOI":"10.1145\/321160.321170"},{"key":"S0960129509990156_ref14","volume-title":"Lehninger Principles of Biochemistry","author":"Nelson","year":"2004"},{"key":"S0960129509990156_ref13","volume-title":"Computation: Finite and Infinite Machines","author":"Minsky","year":"1967"},{"key":"S0960129509990156_ref18","doi-asserted-by":"publisher","DOI":"10.1006\/jcss.1999.1693"},{"key":"S0960129509990156_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcs.2004.09.013"},{"key":"S0960129509990156_ref24","volume-title":"Histology: A Text and Atlas with Correlated Cell and Molecular Biology","author":"Ross","year":"2006"},{"key":"S0960129509990156_ref7","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-36490-0_10"},{"key":"S0960129509990156_ref3","first-page":"37","volume-title":"Proc. of the ESF Exploratory Workshop on Cellular Computing (Complexity Aspects)","author":"Alhazov","year":"2005"},{"key":"S0960129509990156_ref19","first-page":"139","article-title":"Computing with membranes. An introduction","volume":"67","author":"P\u0103un","year":"1999","journal-title":"Bulletin of the EATCS"},{"key":"S0960129509990156_ref2","doi-asserted-by":"publisher","DOI":"10.1142\/S012905410600367X"},{"key":"S0960129509990156_ref1","volume-title":"Molecular Biology of the Cell","author":"Alberts","year":"2002"},{"key":"S0960129509990156_ref23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/11603047_1","article-title":"Computational power of symport\/antiport: history, advances and open problems","volume":"3850","author":"Rogozhin","year":"2006","journal-title":"Springer-Verlag Lecture Notes in Computer Science"},{"key":"S0960129509990156_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-36490-0_17"},{"key":"S0960129509990156_ref10","volume-title":"Molecular Cell Biology","author":"Lodish","year":"2000"},{"key":"S0960129509990156_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3975(02)00659-X"},{"key":"S0960129509990156_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00500-004-0393-4"},{"key":"S0960129509990156_ref26","doi-asserted-by":"publisher","DOI":"10.1007\/11963516_33"},{"key":"S0960129509990156_ref16","doi-asserted-by":"publisher","DOI":"10.1007\/BF03037362"},{"key":"S0960129509990156_ref5","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-31837-8_12"},{"key":"S0960129509990156_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/11963516_2"},{"key":"S0960129509990156_ref17","doi-asserted-by":"publisher","DOI":"10.1142\/S012905410200145X"},{"key":"S0960129509990156_ref12","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-45655-4_32"}],"container-title":["Mathematical Structures in Computer Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0960129509990156","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,29]],"date-time":"2019-04-29T18:19:57Z","timestamp":1556561997000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0960129509990156\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0960129509990156"],"URL":"https:\/\/doi.org\/10.1017\/s0960129509990156","relation":{},"ISSN":["0960-1295","1469-8072"],"issn-type":[{"value":"0960-1295","type":"print"},{"value":"1469-8072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}