{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T08:20:40Z","timestamp":1788337240335,"version":"build-2803163510"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"unspecified","delay-in-days":78,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ASHE"],"published-print":{"date-parts":[[2023]]},"abstract":"Abstract<\/jats:title>\n \n Objective:<\/jats:title>\n To investigate clinically relevant microbiological characteristics of uropathogens and to compare patients with catheter-associated urinary tract infections (CAUTIs) to those with non-CAUTIs.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n All urine cultures from the calendar year 2019 of the Swiss Centre for Antibiotic Resistance database were analyzed. Group differences in the proportions of bacterial species and antibiotic-resistant isolates from CAUTI and non-CAUTI samples were investigated.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Data from 27,158 urine cultures met the inclusion criteria.\n Escherichia coli<\/jats:italic>\n ,\n Klebsiella pneumoniae<\/jats:italic>\n ,\n Pseudomonas aeruginosa<\/jats:italic>\n , and\n Proteus mirabilis<\/jats:italic>\n together represented 70% and 85% of pathogens identified in CAUTI and non-CAUTI samples, respectively.\n Pseudomonas aeruginosa<\/jats:italic>\n was significantly more often detected in CAUTI samples. The overall resistance rate for the empirically often-prescribed antibiotics ciprofloxacin (CIP), norfloxacin (NOR), and trimethoprim-sulfamethoxazole (TMP-SMX) was between 13% and 31%. Except for nitrofurantoin,\n E. coli<\/jats:italic>\n from CAUTI samples were more often resistant (\n P<\/jats:italic>\n \u2264 .048) to all classes of antibiotics analyzed, including third-generation cephalosporines used as surrogate for extended-spectrum \u03b2-lactamase (ESBL). Significanty higher resistance proportions in CAUTI samples versus non-CAUTI samples were observed for CIP (\n P<\/jats:italic>\n = .001) and NOR (\n P<\/jats:italic>\n = .033) in\n K. pneumoniae<\/jats:italic>\n , for NOR (\n P<\/jats:italic>\n = .011) in\n P. mirabilis<\/jats:italic>\n , and for cefepime (\n P<\/jats:italic>\n = .015), and piperacillin-tazobactam (\n P<\/jats:italic>\n = .043) in\n P. aeruginosa.<\/jats:italic>\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n CAUTI pathogens were more often resistant to recommended empirical antibiotics than non-CAUTI pathogens. This finding emphasizes the need for urine sampling for culturing before initiating therapy for CAUTI and the importance of considering therapeutic alternatives.<\/jats:p>\n <\/jats:sec>","DOI":"10.1017\/ash.2022.340","type":"journal-article","created":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T23:52:00Z","timestamp":1679269920000},"source":"Crossref","is-referenced-by-count":30,"title":["Bacterial species and antimicrobial resistance differ between catheter and non\u2013catheter-associated urinary tract infections: Data from a national surveillance network"],"prefix":"10.1017","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0491-1587","authenticated-orcid":false,"given":"St\u00e9phanie","family":"D\u2019Incau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5834-8315","authenticated-orcid":false,"given":"Andrew","family":"Atkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5764-3494","authenticated-orcid":false,"given":"Lorenz","family":"Leitner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0006-7833","authenticated-orcid":false,"given":"Andreas","family":"Kronenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1991-5919","authenticated-orcid":false,"given":"Thomas M.","family":"Kessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0052-3210","authenticated-orcid":false,"given":"Jonas","family":"Marschall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"S2732494X22003400_ref2","doi-asserted-by":"publisher","DOI":"10.2807\/ese.17.46.20316-en"},{"key":"S2732494X22003400_ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-009-8457-0"},{"key":"S2732494X22003400_ref8","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2019.20110"},{"key":"S2732494X22003400_ref7","doi-asserted-by":"publisher","DOI":"10.2807\/ese.18.21.20484-en"},{"key":"S2732494X22003400_ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1306801"},{"key":"S2732494X22003400_ref11","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.174"},{"key":"S2732494X22003400_ref13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1302186"},{"key":"S2732494X22003400_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt208"},{"key":"S2732494X22003400_ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-019-0656-6"},{"key":"S2732494X22003400_ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.3627"},{"key":"S2732494X22003400_ref12","unstructured":"12. Breakpoint tables for interpretation of mics and zone diameters. The European Committee on Antimicrobial Susceptibility Testing website. http:\/\/www.eucast.org\/clinical_breakpoints\/. Accessed January 13, 2023."},{"key":"S2732494X22003400_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2018.07.012"},{"key":"S2732494X22003400_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2020.10.019"},{"key":"S2732494X22003400_ref14","doi-asserted-by":"publisher","DOI":"10.1086\/650482"},{"key":"S2732494X22003400_ref3","doi-asserted-by":"publisher","DOI":"10.1186\/2047-2994-3-23"}],"container-title":["Antimicrobial Stewardship & Healthcare Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2732494X22003400","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T23:52:04Z","timestamp":1679269924000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2732494X22003400\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":15,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023]]}},"alternative-id":["S2732494X22003400"],"URL":"https:\/\/doi.org\/10.1017\/ash.2022.340","relation":{"is-referenced-by":[{"id-type":"doi","id":"10.1186\/s12879-025-12028-5","asserted-by":"object"}]},"ISSN":["2732-494X"],"issn-type":[{"value":"2732-494X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]},"article-number":"e55"}}