{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T19:28:56Z","timestamp":1774034936720,"version":"3.50.1"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T00:00:00Z","timestamp":1731542400000},"content-version":"unspecified","delay-in-days":318,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ASHE"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:sec id=\"S2732494X24004194_as1\">\n\t    <jats:title>Background:<\/jats:title>\n\t    <jats:p>During the past several decades, enterococci are emerging as an important cause of healthcare-associated infections. They have developed resistance to various antimicrobials previously used for the treatment of urinary tract infections (UTIs). This study was aimed to determine the prevalence of <jats:italic>Enterococcus species<\/jats:italic> among urinary tract-infected patients in a tertiary care hospital, in Karnataka, India.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2732494X24004194_as2\">\n\t    <jats:title>Material and Methods:<\/jats:title>\n\t    <jats:p>We have analyzed 4341 culture-positive urine samples received by microbiology laboratory during the year 2021. The bacterial identification was done by matrix-assisted laser desorption ionization-time of flight mass spectrometry. The antibiotic sensitivity was tested by automated VITEK-2\u00ae COMPACT (bioM\u00e9rieux) system.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2732494X24004194_as3\">\n\t    <jats:title>Results:<\/jats:title>\n\t    <jats:p>Among 4341 culture-positive samples, Enterococcal species were isolated from 159 samples. A total of 64.7% of the isolates were identified as <jats:italic>Enterococcus faecalis<\/jats:italic> and 28.3% of the strains as <jats:italic>Enterococcus faecium<\/jats:italic>. All the enterococci were sensitive to linezolid, teicoplanin, and vancomycin, whereas 59.1%, 30.9%, and 23.3% of the strains exhibited resistance to high-level gentamicin, benzylpenicillin, and nitrofurantoin, respectively. 33.67 % of the isolates were identified as multidrug-resistant (MDR) strains as they exhibited resistance to high-level gentamicin, benzylpenicillin, and nitrofurantoin.<\/jats:p>\n\t  <\/jats:sec>\n\t  <jats:sec id=\"S2732494X24004194_as4\">\n\t    <jats:title>Conclusion:<\/jats:title>\n\t    <jats:p>Our study shows the prevalence of <jats:italic>Enterococcus faecalis<\/jats:italic> and high-level gentamicin-resistant enterococcal strains. The MDR pattern of enterococci requires careful consideration of antimicrobial therapy to treat UTIs. The reserved drugs such as linezolid, vancomycin, and teicoplanin should be cautiously used for the treatment of enterococcal UTI.<\/jats:p>\n\t  <\/jats:sec>","DOI":"10.1017\/ash.2024.419","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T06:57:44Z","timestamp":1731567464000},"source":"Crossref","is-referenced-by-count":2,"title":["Antibiogram pattern of Enterococcus species among urinary tract-infected patients visiting tertiary care hospital in Karnataka, India"],"prefix":"10.1017","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0194-5404","authenticated-orcid":false,"given":"Sujatha","family":"Bhat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dushan Uvindu","family":"Gunawardana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delisha Kaur","family":"Boparai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tharinya Kasundie","family":"Bamunusinghe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavin","family":"Krishanth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aarabi","family":"Premakrishna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0495-3194","authenticated-orcid":false,"given":"Nagalakshmi","family":"Narasimhaswamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2024,11,14]]},"reference":[{"key":"S2732494X24004194_ref3","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3432"},{"key":"S2732494X24004194_ref21","doi-asserted-by":"publisher","DOI":"10.1086\/313949"},{"key":"S2732494X24004194_ref4","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2761"},{"key":"S2732494X24004194_ref13","first-page":"1768","article-title":"Impact of enterococcal urinary tract infections in immunocompromised - neoplastic patients","volume":"24","author":"Giannakopoulos","year":"2019","journal-title":"J Buon"},{"key":"S2732494X24004194_ref19","volume-title":"Enterococci: From Commensals to Leading Causes of Drug Resistant Infection","author":"Agudelo Higuita","year":"2014"},{"key":"S2732494X24004194_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.106227"},{"key":"S2732494X24004194_ref17","first-page":"38","article-title":"Prevalence of drug resistance among Enterococcus species isolated from a tertiary care hospital","volume":"1","author":"Bose","year":"2012","journal-title":"Int J Med Heal Sci"},{"key":"S2732494X24004194_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-6553(88)80002-6"},{"key":"S2732494X24004194_ref22","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-023-01287-z"},{"key":"S2732494X24004194_ref2","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v21i2.69055"},{"key":"S2732494X24004194_ref10","first-page":"111","article-title":"Enterococcal infections and antimicrobial resistance","volume":"128","author":"Sood","year":"2008","journal-title":"Indian J. Med. Res."},{"key":"S2732494X24004194_ref14","first-page":"18","article-title":"Prevalence of various enterococcus species and their antibiotic resistance pattern among urinary isolates in tertiary care center in southeastern Rajasthan. IP","volume":"5","author":"Naruka","year":"2019","journal-title":"Int J Med Microbiol Trop Dis"},{"key":"S2732494X24004194_ref8","volume-title":"StatPearls [Internet]","author":"Said","year":"2022"},{"key":"S2732494X24004194_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/ipc.0b013e31815f6586"},{"key":"S2732494X24004194_ref9","volume-title":"StatPearls","author":"Levitus","year":"2023"},{"key":"S2732494X24004194_ref1","first-page":"106","volume-title":"Gram Positive Cocci. 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