{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:15:51Z","timestamp":1785417351844,"version":"3.56.0"},"reference-count":23,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"unspecified","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ASHE"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S2732494X25102696_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Surgical site infections (SSIs) pose a significant healthcare challenge, raising patient morbidity, mortality, and costs. Various intrinsic, patient-specific, and perioperative factors contribute to SSIs. This study aims to identify SSI-associated risk factors, microorganism types, and antibiotic susceptibility patterns in surgical patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X25102696_as2\">\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>This is a matched-case control study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X25102696_as3\">\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>The Lebanese American University Medical Center \u2013 Rizk Hospital, Beirut Lebanon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X25102696_as4\">\n                    <jats:title>Patients:<\/jats:title>\n                    <jats:p>The study included surgical patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X25102696_as5\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective case-control study analyzed data from surgical patients over a five-year period, matching 113 SSI cases with controls in a 1:3 ratio by gender and surgery type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X25102696_as6\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 324 patients (81 cases vs 243 controls), hypoalbuminemia (&lt;3.5 g\/dL) and age \u226565 years were significantly associated with SSIs (\n                      <jats:italic>P<\/jats:italic>\n                      = .025 and\n                      <jats:italic>P<\/jats:italic>\n                      = .039), respectively. Antibiotic redosing was associated with lower odds of SSIs (OR = 0.19,\n                      <jats:italic>P<\/jats:italic>\n                      = .042), indicating a potential protective effect.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X25102696_as7\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      Our findings were consistent with similar studies. Elderly patients and those with hypoalbuminemia were found to be at significantly higher risk of SSIs. Also, antibiotic redosing during prolonged surgeries was associated with reduced SSI risk. In terms of SSI rates, gastrointestinal surgeries (GIs) were the highest with 42.3% of GI cases followed appropriate antibiotic protocols. Like other studies, predominant microorganisms at wound site included\n                      <jats:italic>E. coli<\/jats:italic>\n                      and\n                      <jats:italic>coagulase-negative staphylococci<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ash.2025.10269","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T05:20:41Z","timestamp":1768195241000},"source":"Crossref","is-referenced-by-count":2,"title":["Surgical site infections occurrence and associated risk factors: a matched case-control study"],"prefix":"10.1017","volume":"6","author":[{"given":"Nassab","family":"Fakhreddine","sequence":"first","affiliation":[{"name":"Lebanese American University School of Pharmacy"},{"id":[{"id":"https:\/\/ror.org\/00hqkan37","id-type":"ROR","asserted-by":"publisher"}],"name":"Lebanese American University Medical Center \u2013 Rizk Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1827-2453","authenticated-orcid":false,"given":"Hani","family":"Dimassi","sequence":"additional","affiliation":[{"name":"Lebanese American University School of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7310-9192","authenticated-orcid":false,"given":"Wissam","family":"Kabbara","sequence":"additional","affiliation":[{"name":"Lebanese American University School of Pharmacy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rola","family":"Husni","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00hqkan37","id-type":"ROR","asserted-by":"publisher"}],"name":"Lebanese American University Medical Center \u2013 Rizk Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanaa","family":"Zoghbi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00hqkan37","id-type":"ROR","asserted-by":"publisher"}],"name":"Lebanese American University Medical Center \u2013 Rizk Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanine","family":"Mansour","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00hqkan37","id-type":"ROR","asserted-by":"publisher"}],"name":"Lebanese American University Medical Center \u2013 Rizk Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"S2732494X25102696_ref7","first-page":"004695802311625","article-title":"Global incidence of surgical site infection among patients: systematic review and meta-analysis","volume":"60","author":"Mengistu","year":"2023","journal-title":"J Health Care Org Prov Financ"},{"key":"S2732494X25102696_ref9","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_1838_21"},{"key":"S2732494X25102696_ref11","doi-asserted-by":"publisher","DOI":"10.1080\/21548331.2018.1450605"},{"key":"S2732494X25102696_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2013.01.032"},{"key":"S2732494X25102696_ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.02053.x"},{"key":"S2732494X25102696_ref19","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200608000-00003"},{"key":"S2732494X25102696_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2014.08.008"},{"key":"S2732494X25102696_ref3","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-059018"},{"key":"S2732494X25102696_ref12","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2023.67"},{"key":"S2732494X25102696_ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2017.0904"},{"key":"S2732494X25102696_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2018.01.018"},{"key":"S2732494X25102696_ref10","doi-asserted-by":"publisher","DOI":"10.1177\/155989771214018"},{"key":"S2732494X25102696_ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-021-01392-z"},{"key":"S2732494X25102696_ref16","unstructured":"16. National healthcare Safety Network. Surgical Site Infection Event (SSI). 2023. https:\/\/www.cdc.gov>nhsn>pdfs>pscmanual."},{"key":"S2732494X25102696_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2019.09.015"},{"key":"S2732494X25102696_ref17","first-page":"e42493","article-title":"Healthcare cost and outcomes associated with surgical site infection and patient outcomes in low- and middle-income countries","volume":"15","author":"Costabella","year":"2023","journal-title":"Cureus"},{"key":"S2732494X25102696_ref22","first-page":"e39465","article-title":"Prevalence and risk factors of surgical site infections in a Teaching Medical College in the Trichy District of India","volume":"15","author":"Mohan","year":"2023","journal-title":"Cureus"},{"key":"S2732494X25102696_ref23","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2023.2234082"},{"key":"S2732494X25102696_ref14","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001390"},{"key":"S2732494X25102696_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2016.12.016"},{"key":"S2732494X25102696_ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-016-3519-9"},{"key":"S2732494X25102696_ref5","unstructured":"5. Centers for Disease Control and Prevention. 2009. https:\/\/www.cdc.gov\/hai\/pdfs\/hai\/scott_costpaper.pdf. Accessed July 20, 2023."},{"key":"S2732494X25102696_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.01.015"}],"container-title":["Antimicrobial Stewardship &amp; Healthcare Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2732494X25102696","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T05:20:43Z","timestamp":1768195243000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2732494X25102696\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":23,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026]]}},"alternative-id":["S2732494X25102696"],"URL":"https:\/\/doi.org\/10.1017\/ash.2025.10269","relation":{},"ISSN":["2732-494X"],"issn-type":[{"value":"2732-494X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e17"}}