{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:05:41Z","timestamp":1787501141131,"version":"build-2736575974"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"unspecified","delay-in-days":139,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ASHE"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S2732494X2610401X_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To assess the feasibility of implementing C-reactive protein point-of-care testing (CRP-PoCT) for patients presenting with respiratory tract infections (RTIs) in primary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X2610401X_as2\">\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Feasibility study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X2610401X_as3\">\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>General practice (GP) and community pharmacy in rural Victoria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X2610401X_as4\">\n                    <jats:title>Patients (or Participants):<\/jats:title>\n                    <jats:p>Five GPs and a community pharmacist used CRP-PoCT for RTI patients aged 12\u201365 years for two months between August and December 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X2610401X_as5\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Data on testing, prescribing, and implementation barriers and facilitators were collected from patient records and surveys of GPs and pharmacists. Feasibility outcomes were analyzed using descriptive statistics and content analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X2610401X_as6\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifty-five patients were screened, with recruitment rates of 87.5% (35\/40) in GP clinics and 67% (10\/15) in community pharmacies, and a retention rate of 100%. Adherence to the testing protocol was 100% in both settings; however, adherence to the prescribing protocol was 76% in GP practices and 100% in pharmacies. Common RTI symptoms were cough (70%, n = 30), fever (58%, n = 25), and sore throat (44%, n = 19). Antibiotics were prescribed to 36.4% (12\/33) of GP patients and 10% (1\/10) of pharmacy patients. Pharmacists managed patients with OTC medicines (80%, 8\/10) or immediate GP referral (10%, 1\/10). CRP-PoCT feasibility was rated highly by GPs [median 6\/7 (IQR 4\u20136)] and moderately by the pharmacist (4\/7). Key implementation facilitators identified were nurse\/technician support, medicare funding, clear workflows, and GP\u2013pharmacy collaborative practice agreement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X2610401X_as7\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>With mitigation of practical challenges, CRP-PoCT can be feasibly implemented in rural GP\u2013pharmacy settings to enhance antibiotic stewardship for acute respiratory infections in primary care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ash.2026.10401","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T12:44:50Z","timestamp":1779281090000},"source":"Crossref","is-referenced-by-count":1,"title":["Feasibility of C-reactive protein point-of-care testing for antibiotic stewardship in rural GP\u2013pharmacy settings"],"prefix":"10.1017","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2359-721X","authenticated-orcid":false,"given":"Sajal Kumar","family":"Saha","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02czsnj07","id-type":"ROR","asserted-by":"publisher"}],"name":"Deakin University"},{"name":"Barwon Southwest Public Health Unit"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Muleme","sequence":"additional","affiliation":[{"name":"Barwon Southwest Public Health Unit"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6229-5057","authenticated-orcid":false,"given":"Oliver Van","family":"Hecke","sequence":"additional","affiliation":[{"name":"Ghent University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4902-9448","authenticated-orcid":false,"given":"Mary Lou","family":"Chatterton","sequence":"additional","affiliation":[{"name":"Monash University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Athan","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02czsnj07","id-type":"ROR","asserted-by":"publisher"}],"name":"Deakin University"},{"name":"Barwon Southwest Public Health Unit"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"S2732494X2610401X_ref18","doi-asserted-by":"publisher","DOI":"10.3399\/bjgpopen20X101136"},{"key":"S2732494X2610401X_ref22","unstructured":"22. Folkh\u00e4lsomyndigheten, L\u00e4kemedelsverket och Nationell arbetsgrupp Strama. Behandlingsrekommendationer f\u00f6r vanliga infektioner i \u00f6ppenv\u00e5rd 2023. https:\/\/www.folkhalsomyndigheten.se\/contentassets\/246aa17721b44c5380a0117f6d0aba40\/behandlingsrekommendationer-oppenvard.pdf. Accessed December 25, 2025."},{"key":"S2732494X2610401X_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2022.115493"},{"key":"S2732494X2610401X_ref8","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11091158"},{"key":"S2732494X2610401X_ref30","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-025-21894-2"},{"key":"S2732494X2610401X_ref7","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkae349"},{"key":"S2732494X2610401X_ref10","unstructured":"10. Australian Commission on Safety and Quality in Health Care. Antimicrobial use in the community: 2023. Sydney: ACSQHC; 2024."},{"key":"S2732494X2610401X_ref11","unstructured":"11. Australian Commission on Safety and Quality in Health Care. AURA 2023: fifth Australian report on antimicrobial use and resistance in human health. Sydney: ACSQHC; 2023."},{"key":"S2732494X2610401X_ref25","unstructured":"25. De Bont, EGPM , Greving, JP , Kurver, MJ , et\u00a0al. NHG-standaard Acuut hoesten (M78). 2024; 3.0.\u00a0https:\/\/richtlijnen.nhg.org\/standaarden\/acuut-hoesten. 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