{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T19:36:40Z","timestamp":1788291400503,"version":"build-2803163510"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"unspecified","delay-in-days":175,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ASHE"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S2732494X26107438_as1\">\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Antibiotics are frequently prescribed for acute sinusitis despite national guidelines recommending antibiotics only if specific symptom criteria are met. We aimed to define the proportion of acute sinusitis encounters meeting criteria for antibiotic prescribing, characterize prescribing practices, and identify factors associated with guideline-discordant prescribing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X26107438_as2\">\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>This retrospective cohort study included 1,000 randomly selected adult ambulatory encounters with a primary diagnosis of acute sinusitis between January 1, 2024 and March 31, 2024. Encounter notes were reviewed for appropriate antibiotic prescribing criteria as per national guidelines. Encounters were evaluated for drug selection and duration concordance based on local guidelines. A multivariable logistic regression analysis was performed to identify predictors of inappropriate antibiotic prescribing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X26107438_as3\">\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Emergency departments, urgent care centers, and primary care clinics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X26107438_as4\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Antibiotic prescribing criteria were met for 67.6% of included encounters. Antibiotics were prescribed in 93.5% of encounters that met prescribing criteria, and 80.2% of encounters that did not. Both drug selection and duration were guideline-concordant in 49.2% of total encounters. On multivariable analysis, predictors of inappropriate antibiotic prescribing included cough (OR 2.15, 95% CI 1.08\u20134.29;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.03) and symptom duration between 7 and 9 days (compared to &lt;6 days; OR 7.70, 95% CI 3.24\u201318.31;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001). Electronic encounters were associated with lower odds of prescribing compared to in-person encounters (OR 0.03, 95% CI 0.01\u20130.09;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S2732494X26107438_as5\">\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Most encounters for acute sinusitis result in an antibiotic prescription, despite prescribing criteria not being met. These findings may aid antimicrobial stewardship programs in benchmarking and optimizing antibiotic prescribing for acute sinusitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/ash.2026.10743","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T07:42:16Z","timestamp":1782373336000},"source":"Crossref","is-referenced-by-count":1,"title":["Ambulatory antibiotic prescribing for acute sinusitis: a multicenter, retrospective cohort study evaluating appropriateness"],"prefix":"10.1017","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0200-1782","authenticated-orcid":false,"given":"Kellie","family":"Arensman Hannan","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02qp3tb03","id-type":"ROR","asserted-by":"publisher"}],"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0778-3901","authenticated-orcid":false,"given":"Dan","family":"Ilges","sequence":"additional","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4040-2755","authenticated-orcid":false,"given":"Kimberly T.","family":"Le","sequence":"additional","affiliation":[{"name":"R. Ken Coit College of Pharmacy, The University of Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8783-0191","authenticated-orcid":false,"given":"Kristin","family":"Cole","sequence":"additional","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan W.","family":"Stevens","sequence":"additional","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8372-3316","authenticated-orcid":false,"given":"Kelsey","family":"Jensen","sequence":"additional","affiliation":[{"name":"Mayo Clinic Health System"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"key":"S2732494X26107438_ref22","doi-asserted-by":"publisher","DOI":"10.1177\/00034894241230365"},{"key":"S2732494X26107438_ref23","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.7.748"},{"key":"S2732494X26107438_ref24","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.13011"},{"key":"S2732494X26107438_ref2","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino12.000"},{"key":"S2732494X26107438_ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.4151"},{"key":"S2732494X26107438_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofae420"},{"key":"S2732494X26107438_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa736"},{"key":"S2732494X26107438_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2012.09.003"},{"key":"S2732494X26107438_ref13","doi-asserted-by":"publisher","DOI":"10.1089\/tmj.2020.0047"},{"key":"S2732494X26107438_ref19","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_446_23"},{"key":"S2732494X26107438_ref7","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis370"},{"key":"S2732494X26107438_ref20","first-page":"S1","article-title":"Clinical practice guideline (Update): adult sinusitis","volume":"152","author":"Rosenfeld","year":"2015","journal-title":"Otolaryngol Head Neck Surg"},{"key":"S2732494X26107438_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.12.002"},{"key":"S2732494X26107438_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofad585"},{"key":"S2732494X26107438_ref3","doi-asserted-by":"publisher","DOI":"10.1086\/591126"},{"key":"S2732494X26107438_ref14","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2022.19"},{"key":"S2732494X26107438_ref5","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz910"},{"key":"S2732494X26107438_ref8","first-page":"S1","article-title":"Clinical practice guideline: adult sinusitis update","volume":"173","author":"Payne","year":"2025","journal-title":"Otolaryngol--head neck surg"},{"key":"S2732494X26107438_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2021.10.039"},{"key":"S2732494X26107438_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocaf122"},{"key":"S2732494X26107438_ref12","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofz393"},{"key":"S2732494X26107438_ref16","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1601705"},{"key":"S2732494X26107438_ref21","first-page":"CD006089","article-title":"Antibiotics for acute rhinosinusitis in adults","volume":"9","author":"Lemiengre","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"S2732494X26107438_ref17","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.6.1209"}],"container-title":["Antimicrobial Stewardship &amp; Healthcare Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2732494X26107438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T07:42:18Z","timestamp":1782373338000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2732494X26107438\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026]]}},"alternative-id":["S2732494X26107438"],"URL":"https:\/\/doi.org\/10.1017\/ash.2026.10743","relation":{},"ISSN":["2732-494X"],"issn-type":[{"value":"2732-494X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e193"}}