{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T05:46:57Z","timestamp":1785908817254,"version":"3.56.0"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"unspecified","delay-in-days":216,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ASHE"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>When a suspected viral hemorrhagic fever (VHF) case presents to a healthcare facility, healthcare personnel must be able to safely provide initial stabilizing care, which may involve performing basic routine laboratory testing. Current gaps exist in the ability of frontline acute care hospitals to safely perform routine laboratory tests on patients with suspected VHFs that generate category A waste. This review outlines a potential solution for frontline acute care hospitals to perform electrolytes, hemoglobin\/hematocrit, and malaria testing, in accordance with National Special Pathogens System guidelines, in the patient\u2019s isolation room. We discuss guidance on laboratory risk assessment, equipment considerations, space requirements, staffing solutions, waste management, cost estimates, and remaining challenges. Our manuscript provides frontline acute care hospitals with a potential solution to safely provide a minimum set of routine laboratory tests for patients with suspected VHF.<\/jats:p>","DOI":"10.1017\/ash.2026.10817","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T04:58:55Z","timestamp":1785905935000},"source":"Crossref","is-referenced-by-count":0,"title":["Point-of-care routine laboratory testing for patients with suspected viral hemorrhagic fevers"],"prefix":"10.1017","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-6220-3897","authenticated-orcid":false,"given":"Anne Liston","family":"Sullivan","sequence":"first","affiliation":[{"name":"Greater New York Hospital Association"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8847-2763","authenticated-orcid":false,"given":"Jessica L.","family":"Jacobson","sequence":"additional","affiliation":[{"name":"NYC Health + Hospitals\/Bellevue"},{"name":"NYU Grossman School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Dhagat","sequence":"additional","affiliation":[{"name":"NYC Health + Hospitals\/Bellevue"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1284-6428","authenticated-orcid":false,"given":"Madeline","family":"DiLorenzo","sequence":"additional","affiliation":[{"name":"NYC Health + Hospitals\/Bellevue"},{"id":[{"id":"https:\/\/ror.org\/0190ak572","id-type":"ROR","asserted-by":"publisher"}],"name":"NYU Grossman School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Douyon","sequence":"additional","affiliation":[{"name":"NYC Health + Hospitals\/Bellevue"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6488-9703","authenticated-orcid":false,"given":"Jamie","family":"Figueredo","sequence":"additional","affiliation":[{"name":"NYC Health + Hospitals\/Woodhull"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Harris","sequence":"additional","affiliation":[{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9304-6563","authenticated-orcid":false,"given":"Dana","family":"Mazo","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0190ak572","id-type":"ROR","asserted-by":"publisher"}],"name":"NYU Grossman School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2922-3121","authenticated-orcid":false,"given":"Jeffrey","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Lenox Hill Hospital-Northwell Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1801-6628","authenticated-orcid":false,"given":"Gregory","family":"Weston","sequence":"additional","affiliation":[{"name":"Montefiore Medical Center"},{"name":"Albert Einstein College of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0056-8224","authenticated-orcid":false,"given":"Justin","family":"Chan","sequence":"additional","affiliation":[{"name":"NYC Health + Hospitals\/Bellevue"},{"id":[{"id":"https:\/\/ror.org\/0190ak572","id-type":"ROR","asserted-by":"publisher"}],"name":"NYU Grossman School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,8,5]]},"reference":[{"key":"S2732494X26108171_ref5","unstructured":"5. New and Revised Requirements for Infection Prevention and Control for Critical Access Hospitals and Hospitals. The Joint Commission website; 2023. https:\/\/digitalassets.jointcommission.org\/api\/public\/content\/01f83448fbb54ba7b9225048834e7247?v=4e3fcba2. Accessed June 26, 2026."},{"key":"S2732494X26108171_ref10","doi-asserted-by":"publisher","DOI":"10.1086\/518173"},{"key":"S2732494X26108171_ref4","doi-asserted-by":"publisher","DOI":"10.1017\/ash.2026.10319"},{"key":"S2732494X26108171_ref1","first-page":"1507","article-title":"Basic and translational state of the science working group of the national emerging special pathogens training and education center\u2019s special pathogens research network preparedness and response considerations for high-consequence infectious disease","volume":"31","author":"Chan","year":"2025","journal-title":"Emerg Infect Dis"},{"key":"S2732494X26108171_ref12","unstructured":"12. National Special Pathogen System (NSPS). National Emerging Special Pathogens Training and Education Center (NETEC) website; 2026. https:\/\/netec.org\/nsps\/. Accessed June 16, 2026."},{"key":"S2732494X26108171_ref20","doi-asserted-by":"publisher","DOI":"10.1089\/hs.2024.0013"},{"key":"S2732494X26108171_ref8","first-page":"1","article-title":"Assessing current capabilities and barriers to performing routine laboratory tests on patients with suspected high consequence infectious disease at frontline acute care hospitals","volume":"28","author":"DiLorenzo","year":"2026","journal-title":"Infect Control Hosp Epidemiol"},{"key":"S2732494X26108171_ref23","unstructured":"23. Infection Prevention and Control Recommendations for Patients in U.S. Hospitals Who are Suspected or Confirmed to have Selected Viral Hemorrhagic Fevers (VHF). Centers for Disease Control and Prevention website; 2026. https:\/\/www.cdc.gov\/viral-hemorrhagic-fevers\/hcp\/infection-control\/index.html. Accessed June 28, 2026."},{"key":"S2732494X26108171_ref2","unstructured":"2. High Consequence Infectious Diseases (HCID). UK Health Security Agency website; 2018. https:\/\/www.gov.uk\/guidance\/high-consequence-infectious-diseases-hcid. Accessed June 24, 2026."},{"key":"S2732494X26108171_ref18","unstructured":"18. Clinical Laboratory Evaluation Program Guide. New York State Department of Health, Wadsworth Center website; 2026. https:\/\/www.wadsworth.org\/sites\/default\/files\/2026-03\/CLEPGUIDE_March%202026%20FINAL.pdf. Accessed June 24, 2026."},{"key":"S2732494X26108171_ref24","unstructured":"24. Interim Guidance for Environmental Infection Control in Hospitals; 2024. https:\/\/www.cdc.gov\/viral-hemorrhagic-fevers\/hcp\/infection-control\/environmental-infection-control-hospitals.html. Accessed June 28, 2026."},{"key":"S2732494X26108171_ref21","unstructured":"21. Space Recommendations for Donning and Doffing Personal Protective Equipment (PPE) in Biocontainment Areas. National Emerging Special Pathogens Training & Education Center (NETEC) website; 2022. https:\/\/repository.netecweb.org\/items\/show\/1708. Accessed June 26, 2026."},{"key":"S2732494X26108171_ref22","unstructured":"22. Guidelines for Design and Construction of Hospitals. Facility Guidelines Institute website; 2022. https:\/\/fgiguidelines.org. Accessed June 26, 2026."},{"key":"S2732494X26108171_ref14","unstructured":"14. Laboratory Minimum Testing Capabilities for Evaluation of Patients with Suspected Viral hemorrhagic Fever (VHF). New York State Department of Health website; 2025. https:\/\/www.health.ny.gov\/diseases\/communicable\/ebola\/providers\/docs\/laboratory_minimum_testing_capabilities.pdf. Accessed June 5, 2026."},{"key":"S2732494X26108171_ref15","unstructured":"15. Title 10, Part 405\u2014Hospitals: Minimum Standards. New York Codes, Rules and Regulations website; 2025. https:\/\/regs.health.ny.gov\/content\/part-405-hospitals-minimum-standards. Accessed June 5, 2026."},{"key":"S2732494X26108171_ref25","unstructured":"25. NETEC Announces $37.5M Initiative to Strengthen National Health Security and Expand Special Pathogen Preparedness. National Emerging Special Pathogens Training & Education Center (NETEC) website; 2025. https:\/\/netec.org\/2025\/10\/15\/netec-announces-37-5m-initiative-to-strengthen-national-health-security-and-expand-special-pathogen-preparedness\/. Accessed June 26, 2026."},{"key":"S2732494X26108171_ref19","unstructured":"19. Handling VHF-Associated Waste. Centers for Disease Control and Prevention website; 2024. https:\/\/www.cdc.gov\/viral-hemorrhagic-fevers\/hcp\/infection-control\/handling-vhf-associated-waste.html. Accessed June 26, 2026."},{"key":"S2732494X26108171_ref6","unstructured":"6. Planning Guidance for Handling Category A Solid Waste. US Department of Transportation website; 2024. https:\/\/www.phmsa.dot.gov\/transporting-infectious-substances\/planning-guidance-handling-category-solid-waste. Accessed June 26, 2026."},{"key":"S2732494X26108171_ref9","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.00903-26"},{"key":"S2732494X26108171_ref17","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01096-19"},{"key":"S2732494X26108171_ref11","unstructured":"11. WHO Guidelines for the Clinical Management of Filovirus Disease. World Health Organization website; 2026. https:\/\/www.who.int\/publications\/i\/item\/B09774. Accessed July 27, 2026."},{"key":"S2732494X26108171_ref3","unstructured":"3. Disease Outbreak News, Bundibugyo Virus Disease, Democratic Republic of the Congo and Uganda. World Health Organization website; 2026. https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2026-DON605. Accessed June 26, 2026."},{"key":"S2732494X26108171_ref13","unstructured":"13. Guidance on Performing Routine Diagnostic Testing for Patients with Suspected VHFs or Other High-Consequence Disease. Centers for Disease Control and Prevention website; 2026. https:\/\/www.cdc.gov\/viral-hemorrhagic-fevers\/php\/laboratories\/guidance-on-performing-routine-diagnostic-testing-for-patients-with-suspected-vhfs-or-other.html. Accessed June 30, 2026."},{"key":"S2732494X26108171_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2024.143"},{"key":"S2732494X26108171_ref16","unstructured":"16. Ebola Disease Outbreak in the Democratic Republic of the Congo and Uganda Update. California Department of Public Health website; 2026. https:\/\/www.cdph.ca.gov\/Programs\/OPA\/Pages\/CAHAN\/Ebola-Disease-Outbreak-in-the-Democratic-Republic-of-the-Congo-and-Uganda-Update.aspx#. Accessed June 30, 2026."}],"container-title":["Antimicrobial Stewardship &amp; Healthcare Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S2732494X26108171","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T04:58:59Z","timestamp":1785905939000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S2732494X26108171\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026]]}},"alternative-id":["S2732494X26108171"],"URL":"https:\/\/doi.org\/10.1017\/ash.2026.10817","relation":{},"ISSN":["2732-494X"],"issn-type":[{"value":"2732-494X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"e237"}}